ATE278706T1 - Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen - Google Patents

Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen

Info

Publication number
ATE278706T1
ATE278706T1 AT02704642T AT02704642T ATE278706T1 AT E278706 T1 ATE278706 T1 AT E278706T1 AT 02704642 T AT02704642 T AT 02704642T AT 02704642 T AT02704642 T AT 02704642T AT E278706 T1 ATE278706 T1 AT E278706T1
Authority
AT
Austria
Prior art keywords
insoluble protein
vibrating membranes
membranes filtration
concentrating
concentrating insoluble
Prior art date
Application number
AT02704642T
Other languages
English (en)
Inventor
Benoit Champluvier
Philippe Jean Gervais Permanne
S A Biologicals
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Application granted granted Critical
Publication of ATE278706T1 publication Critical patent/ATE278706T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/16—Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/16—Rotary, reciprocated or vibrated modules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/04—Specific process operations in the feed stream; Feed pretreatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
AT02704642T 2001-01-09 2002-01-07 Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen ATE278706T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0100513.1A GB0100513D0 (en) 2001-01-09 2001-01-09 Process
PCT/EP2002/000063 WO2002055539A1 (en) 2001-01-09 2002-01-07 Process to concentrate insoluble proteins by vibrating membrane filtration

Publications (1)

Publication Number Publication Date
ATE278706T1 true ATE278706T1 (de) 2004-10-15

Family

ID=9906486

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02704642T ATE278706T1 (de) 2001-01-09 2002-01-07 Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen

Country Status (9)

Country Link
US (1) US6939697B2 (de)
EP (1) EP1349868B1 (de)
JP (1) JP4074519B2 (de)
AT (1) ATE278706T1 (de)
CA (1) CA2433689A1 (de)
DE (1) DE60201496T2 (de)
ES (1) ES2229091T3 (de)
GB (1) GB0100513D0 (de)
WO (1) WO2002055539A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2069054A1 (de) * 2006-08-30 2009-06-17 GE Healthcare Bio-Sciences Corp. System und verfahren zur charakterisierung von membranen und membranfiltriervorrichtungen
ATE496935T1 (de) * 2007-02-22 2011-02-15 Baxter Int Verfahren zur aufreinigung hydrophober proteine
US8546127B2 (en) * 2008-06-30 2013-10-01 General Electric Company Bacteria/RNA extraction device
US8158405B2 (en) * 2008-06-30 2012-04-17 General Electric Company Process for concentrating and processing fluid samples
DE102009010484A1 (de) * 2009-02-25 2010-08-26 Gea Westfalia Separator Gmbh Filtrationsverfahren und -vorrichtung
SG10201500036WA (en) 2010-04-30 2015-02-27 Asahi Kasei Pharma Corp Highly-purified soluble thrombomodulin and method for producing same
US9475709B2 (en) 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
US9028663B2 (en) 2012-03-21 2015-05-12 Lockheed Martin Corporation Molecular separation device
US20130277305A1 (en) * 2012-04-19 2013-10-24 Lockheed Martin Corporation Selectively perforated graphene membranes for compound harvest, capture and retention
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US9844757B2 (en) 2014-03-12 2017-12-19 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US10376845B2 (en) 2016-04-14 2019-08-13 Lockheed Martin Corporation Membranes with tunable selectivity
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US9610546B2 (en) 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
TW201504140A (zh) 2013-03-12 2015-02-01 Lockheed Corp 形成具有均勻孔尺寸之多孔石墨烯之方法
US9572918B2 (en) 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
CN105940479A (zh) 2014-01-31 2016-09-14 洛克希德马丁公司 使用宽离子场穿孔二维材料
CN106029596A (zh) 2014-01-31 2016-10-12 洛克希德马丁公司 采用多孔非牺牲性支撑层的二维材料形成复合结构的方法
JP2017534311A (ja) 2014-09-02 2017-11-24 ロッキード・マーチン・コーポレーション 二次元膜材料をベースとする血液透析膜および血液濾過膜、ならびにそれを用いた方法
JP2018528144A (ja) 2015-08-05 2018-09-27 ロッキード・マーチン・コーポレーション グラフェン系材料の穿孔可能なシート
WO2017023377A1 (en) 2015-08-06 2017-02-09 Lockheed Martin Corporation Nanoparticle modification and perforation of graphene
EP3442697A4 (de) 2016-04-14 2020-03-18 Lockheed Martin Corporation Selektive grenzflächenminderung von graphendefekten
WO2017180134A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
EP3442739A4 (de) 2016-04-14 2020-03-04 Lockheed Martin Corporation Verfahren zur behandlung von graphenfolien für grossflächigen transfer mittels free-float-verfahren
KR20180133430A (ko) 2016-04-14 2018-12-14 록히드 마틴 코포레이션 결함 형성 또는 힐링의 인 시츄 모니터링 및 제어를 위한 방법
EP3442786A4 (de) 2016-04-14 2020-03-18 Lockheed Martin Corporation Zweidimensionale membranstrukturen mit strömungskanälen
US20200109388A1 (en) * 2017-04-03 2020-04-09 Novozymes A/S Recovery Process

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900449A (en) * 1987-05-20 1990-02-13 Gelman Sciences Filtration membranes and method of making the same
US4872988A (en) * 1988-02-02 1989-10-10 Culkin Joseph B Method and device for separation of colloidal suspensions
US4952317A (en) 1989-03-10 1990-08-28 Bradley Culkin Device and method for filtering a colloidal suspension
US5468844A (en) * 1994-01-07 1995-11-21 Protose Technologies Inc. Process for the membrane-filtering of protein solutions
US5911880A (en) 1995-12-15 1999-06-15 Research Corporation Technologies, Inc. Self-wetting membranes from engineering plastics
ATE346676T1 (de) 1996-09-06 2006-12-15 Pall Corp Scherkraft trennverfahren und vorrichtung

Also Published As

Publication number Publication date
EP1349868A1 (de) 2003-10-08
DE60201496D1 (de) 2004-11-11
DE60201496T2 (de) 2006-03-09
ES2229091T3 (es) 2005-04-16
JP4074519B2 (ja) 2008-04-09
US20040072314A1 (en) 2004-04-15
JP2004532183A (ja) 2004-10-21
EP1349868B1 (de) 2004-10-06
CA2433689A1 (en) 2002-07-18
GB0100513D0 (en) 2001-02-21
US6939697B2 (en) 2005-09-06
WO2002055539A1 (en) 2002-07-18

Similar Documents

Publication Publication Date Title
ATE278706T1 (de) Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen
ATE278785T1 (de) Neues verfahren zur gewinnung und reinigung von fusionsproteinen
DE60207848D1 (de) Verfahren zur herstellung von konzentrierten menschlichen immunoglobulinen für die therapeutische verwendung
ATE445642T1 (de) Trennung von polypeptiden mit einer racemisierten aminosäure
ATE318146T1 (de) Verfahren zur aufkonzentrierung von antikörperlösungen
DE69629042D1 (de) Polysulfon-membran zur reinigung von blut
ATE384742T1 (de) Verfahren zur reinigung von preproinsulin
DE60143325D1 (de) Verfahren zur Analyse von Proteinen durch isoelektrische Fokussierung einer Lösung
DE69829930D1 (de) Verfahren zur konzentrierung wässriger fluorpolymerdispersionen
DE602005021485D1 (de) Verfahren und zusammensetzungen mit molkeproteinisolaten
DE69834533D1 (de) Verfahren zur Protein-Herstellung
DE59601822D1 (de) Verfahren zur herstellung von weizenproteinhydrolysaten
ATE449104T1 (de) Verfahren zur reinigung von fibrinogen
DE69626917D1 (de) Verfahren zur Herstellung eines löslichen Proteins mittels Bakterien
ATE245192T1 (de) Verfahren zur herstellung von gereinigten papillomavirus proteinen
AU2001279639A1 (en) Method for electrophoretically separating membrane proteins
DE10082576D2 (de) Verfahren zur Herstellung eines Kanalbildenden Proteins
DE60003282D1 (de) Verfahren zur reinigung von hyaluronsäure mit hohem molekulargewicht
ATE416619T1 (de) Verfahren zur dearomatisierung von molkeprotein
ATE417056T1 (de) Verfahren zur proteinreinigung
DE60027932D1 (de) Verfahren zur herstellung von proteinhydrolysaten
DK1105508T3 (da) Fremgangsmåde til oprensning af biomolekyle- eller proteinkomplekser
ATE434036T1 (de) Filtrationsverfahren zur trennung von viren
DE69523271D1 (de) Verfahren zur Pufferung von konzentrierten wässerigen Aufschlämmungen
ATE291230T1 (de) Verwendung von methoden zur identifizierung von hydrophilen signal-oligopeptiden

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties