ATE280758T1 - Mittel zum schutz von nervenzellen - Google Patents
Mittel zum schutz von nervenzellenInfo
- Publication number
- ATE280758T1 ATE280758T1 AT97924254T AT97924254T ATE280758T1 AT E280758 T1 ATE280758 T1 AT E280758T1 AT 97924254 T AT97924254 T AT 97924254T AT 97924254 T AT97924254 T AT 97924254T AT E280758 T1 ATE280758 T1 AT E280758T1
- Authority
- AT
- Austria
- Prior art keywords
- agents
- nerve cells
- protecting nerve
- agent
- protecting
- Prior art date
Links
- 210000002569 neuron Anatomy 0.000 title abstract 2
- HIYWOHBEPVGIQN-UHFFFAOYSA-N 1h-benzo[g]indole Chemical class C1=CC=CC2=C(NC=C3)C3=CC=C21 HIYWOHBEPVGIQN-UHFFFAOYSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000007850 degeneration Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000004090 neuroprotective agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15898596 | 1996-05-30 | ||
| JP33276496 | 1996-11-28 | ||
| PCT/JP1997/001828 WO1997045410A1 (en) | 1996-05-30 | 1997-05-29 | Nerve cell protective agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE280758T1 true ATE280758T1 (de) | 2004-11-15 |
Family
ID=26485930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97924254T ATE280758T1 (de) | 1996-05-30 | 1997-05-29 | Mittel zum schutz von nervenzellen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6040331A (de) |
| EP (1) | EP0858996B1 (de) |
| KR (1) | KR19990035883A (de) |
| AT (1) | ATE280758T1 (de) |
| CA (1) | CA2228268A1 (de) |
| DE (1) | DE69731368T2 (de) |
| TW (1) | TW430660B (de) |
| WO (1) | WO1997045410A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1056452B1 (de) * | 1998-02-23 | 2006-07-19 | South Alabama Medical Science Foundation | Indole-3-propionsäure, ihre salze und ester als arzneimittel |
| US8008283B2 (en) * | 1998-12-23 | 2011-08-30 | Neurotherapeutics Pharma, Inc. | Methods and compositions for the treatment of neuropsychiatric disorders |
| US20060025387A1 (en) * | 1998-12-23 | 2006-02-02 | Cytoscan Sciences Llc | Compositions and methods for the treatment of disorders of the central and peripheral nervous systems |
| US7214711B2 (en) * | 1998-12-23 | 2007-05-08 | Neurotherapeutics Pharma Llc | Method of treating migraine headache without aura |
| US8722668B2 (en) * | 1998-12-23 | 2014-05-13 | Daryl W. Hochman | Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders |
| EP1163220A1 (de) * | 1999-03-23 | 2001-12-19 | Sumitomo Pharmaceuticals Company, Limited | Tricyclische indol-2-carbonsäure verbindung als nmda rezeptor-antagonist |
| US6906096B2 (en) * | 2002-06-28 | 2005-06-14 | Irm Llc | 4,7-Disubstituted indoles and methods of making |
| US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| MX2008000462A (es) * | 2005-07-14 | 2008-03-10 | Irm Llc | Compuestos heterotetraciclicos como mimeticos de tpo. |
| WO2007030939A2 (en) | 2005-09-15 | 2007-03-22 | Painceptor Pharma Corporation | Methods of modulating neurotrophin-mediated activity |
| JP2009511629A (ja) * | 2005-10-17 | 2009-03-19 | ニューロセラピューティクス ファーマ， インコーポレイテッド | 中枢神経系疾患の調節に有用な利尿薬様化合物類似体 |
| US20100172909A1 (en) * | 2005-10-24 | 2010-07-08 | Masahiro Nishibori | Cerebral edema suppressant |
| CN105636440A (zh) | 2013-10-17 | 2016-06-01 | 美国陶氏益农公司 | 制备杀虫化合物的方法 |
| US9174962B2 (en) | 2013-10-17 | 2015-11-03 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| WO2015058028A1 (en) * | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| JP2016536295A (ja) | 2013-10-17 | 2016-11-24 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除性化合物の製造方法 |
| WO2015058022A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| WO2015058024A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| US9085564B2 (en) | 2013-10-17 | 2015-07-21 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| EP3174856A4 (de) | 2014-07-31 | 2018-01-10 | Dow AgroSciences LLC | Verfahren zur herstellung von 3(-3-chlor-1h-pyrazol-1-yl)pyridin |
| JP2017523168A (ja) | 2014-07-31 | 2017-08-17 | ダウ アグロサイエンシィズ エルエルシー | ３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの製造方法 |
| BR112017000565A2 (pt) | 2014-07-31 | 2017-11-07 | Dow Agrosciences Llc | processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina |
| EP3183238A4 (de) | 2014-08-19 | 2018-01-10 | Dow AgroSciences LLC | Verfahren zur herstellung von 3(-3-chlor-1h-pyrazol-1-yl)pyridin |
| BR112017004613A2 (pt) | 2014-09-12 | 2017-12-05 | Dow Agrosciences Llc | processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina |
| US20160332962A1 (en) * | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| WO2018125815A1 (en) | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| CN110325036B (zh) | 2016-12-29 | 2021-10-26 | 美国陶氏益农公司 | 用于制备杀虫化合物的方法 |
| EP3983340B1 (de) * | 2019-06-12 | 2023-08-02 | Nouryon Chemicals International B.V. | Verfahren zur isolierung von carbonsäure aus einem wässrigen seitenstrom |
| EP3983368B1 (de) | 2019-06-12 | 2023-08-02 | Nouryon Chemicals International B.V. | Verfahren zur herstellung von diacylperoxiden |
| EP3983369B1 (de) | 2019-06-12 | 2023-08-02 | Nouryon Chemicals International B.V. | Verfahren zur herstellung von diacylperoxiden |
| JP7335362B2 (ja) | 2019-06-12 | 2023-08-29 | ヌーリオン ケミカルズ インターナショナル ベスローテン フェノーツハップ | 過酸化ジアシルを生成するためのプロセス |
| WO2020249689A1 (en) | 2019-06-12 | 2020-12-17 | Nouryon Chemicals International B.V. | Process for the production of peroxyesters |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346573A1 (de) * | 1983-12-23 | 1985-07-04 | Troponwerke GmbH & Co KG, 5000 Köln | 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung |
| DE3525564A1 (de) * | 1985-07-15 | 1987-02-05 | Schering Ag | Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
| DE3718892A1 (de) * | 1987-06-05 | 1988-12-22 | Bayer Ag | Polyhydrobenz(c,d)indol-sulfonamide |
| DE3809155A1 (de) * | 1988-03-18 | 1989-09-28 | Bayer Ag | 1,3,4,5-tetrahydrobenz-(c,d)-indole |
| US5039820A (en) * | 1990-02-26 | 1991-08-13 | Eli Lilly And Company | 4-amino-6-iodo-hexahydrobenz(cd)indoles |
| US5244912A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof |
| WO1993022313A1 (fr) * | 1992-04-27 | 1993-11-11 | Mochida Pharmaceutical Co., Ltd. | Compose tricyclique dote d'un effet antiallergique |
| JPH07188166A (ja) * | 1993-11-17 | 1995-07-25 | Sumitomo Pharmaceut Co Ltd | 三環性インドール−２−カルボン酸誘導体 |
| TW280819B (de) * | 1993-11-17 | 1996-07-11 | Sumitomo Pharma | |
| FR2732964B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
-
1997
- 1997-05-27 TW TW086107186A patent/TW430660B/zh active
- 1997-05-29 CA CA002228268A patent/CA2228268A1/en not_active Abandoned
- 1997-05-29 AT AT97924254T patent/ATE280758T1/de not_active IP Right Cessation
- 1997-05-29 DE DE69731368T patent/DE69731368T2/de not_active Expired - Fee Related
- 1997-05-29 EP EP97924254A patent/EP0858996B1/de not_active Expired - Lifetime
- 1997-05-29 WO PCT/JP1997/001828 patent/WO1997045410A1/ja not_active Ceased
- 1997-05-29 KR KR1019980700544A patent/KR19990035883A/ko not_active Withdrawn
- 1997-05-29 US US09/011,260 patent/US6040331A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW430660B (en) | 2001-04-21 |
| EP0858996A4 (de) | 2001-03-21 |
| EP0858996A1 (de) | 1998-08-19 |
| KR19990035883A (ko) | 1999-05-25 |
| WO1997045410A1 (en) | 1997-12-04 |
| DE69731368D1 (de) | 2004-12-02 |
| US6040331A (en) | 2000-03-21 |
| CA2228268A1 (en) | 1997-12-04 |
| DE69731368T2 (de) | 2005-03-17 |
| EP0858996B1 (de) | 2004-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |