ATE281232T1 - Verfahren zur behandlung von nukleinsaüreproben mittels schwingung eines teiles einer kartuschenwandung, system und kartusche zur durchführung desselben - Google Patents

Verfahren zur behandlung von nukleinsaüreproben mittels schwingung eines teiles einer kartuschenwandung, system und kartusche zur durchführung desselben

Info

Publication number
ATE281232T1
ATE281232T1 AT00811252T AT00811252T ATE281232T1 AT E281232 T1 ATE281232 T1 AT E281232T1 AT 00811252 T AT00811252 T AT 00811252T AT 00811252 T AT00811252 T AT 00811252T AT E281232 T1 ATE281232 T1 AT E281232T1
Authority
AT
Austria
Prior art keywords
cartridge
active surface
wall
segment
swinging
Prior art date
Application number
AT00811252T
Other languages
English (en)
Inventor
Marcel Aeschlimann
Peter Vischer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE281232T1 publication Critical patent/ATE281232T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/29—Mixing by periodically deforming flexible tubular members through which the material is flowing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0436—Moving fluids with specific forces or mechanical means specific forces vibrational forces acoustic forces, e.g. surface acoustic waves [SAW]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AT00811252T 2000-12-28 2000-12-28 Verfahren zur behandlung von nukleinsaüreproben mittels schwingung eines teiles einer kartuschenwandung, system und kartusche zur durchführung desselben ATE281232T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00811252A EP1226863B1 (de) 2000-12-28 2000-12-28 Verfahren zur Behandlung von Nukleinsaüreproben mittels Schwingung eines Teiles einer Kartuschenwandung, System und Kartusche zur Durchführung desselben

Publications (1)

Publication Number Publication Date
ATE281232T1 true ATE281232T1 (de) 2004-11-15

Family

ID=8175114

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00811252T ATE281232T1 (de) 2000-12-28 2000-12-28 Verfahren zur behandlung von nukleinsaüreproben mittels schwingung eines teiles einer kartuschenwandung, system und kartusche zur durchführung desselben

Country Status (5)

Country Link
US (1) US6872566B2 (de)
EP (1) EP1226863B1 (de)
AT (1) ATE281232T1 (de)
DE (1) DE60015590T2 (de)
ES (1) ES2232407T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224976B1 (de) * 2000-12-28 2006-08-23 F. Hoffmann-La Roche Ag Verfahren, System und Patrone zur Verarbeitung einer Nukleinsäure-Probe durch Oszillation der Patrone
US20050214209A1 (en) * 2001-05-25 2005-09-29 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to TRAIL receptors
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
EP2041573B1 (de) * 2006-06-23 2019-09-04 PerkinElmer Health Sciences, Inc. Verfahren und vorrichtung für mikrofluidische point-of-care-immunoassays
WO2008012550A2 (en) 2006-07-28 2008-01-31 Diagnostics For The Real World, Ltd. Device, system and method for processing a sample
US9707556B2 (en) 2007-08-17 2017-07-18 Diagnostics For The Real World, Ltd. Device, system and method for processing a sample
US9132423B2 (en) 2010-01-29 2015-09-15 Micronics, Inc. Sample-to-answer microfluidic cartridge
JP6190822B2 (ja) 2012-01-09 2017-08-30 マイクロニクス， インコーポレイテッド マイクロ流体リアクタシステム
EP2935559B1 (de) 2012-12-21 2020-09-16 PerkinElmer Health Sciences, Inc. Fluoreszenznachweissystem
WO2014100743A2 (en) 2012-12-21 2014-06-26 Micronics, Inc. Low elasticity films for microfluidic use
EP2935908B1 (de) 2012-12-21 2019-08-14 PerkinElmer Health Sciences, Inc. Fluidkreisläufe und zugehörige herstellungsverfahren
EP2994543B1 (de) 2013-05-07 2018-08-15 Micronics, Inc. Vorrichtung zur herstellung und analyse von nukleinsäuren
EP2994532B1 (de) 2013-05-07 2017-11-15 Micronics, Inc. Verfahren zur herstellung von nukleinsäurehaltigen proben mittels tonmineralien und alkalischen lösungen
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
EP4599933A3 (de) * 2018-09-20 2025-11-12 Cepheid System, vorrichtung und verfahren zur probenverarbeitung mit halbleiterdetektionschips

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4095288A (en) * 1975-05-07 1978-06-13 Garlinghouse Leslie H Variable agitator mixer
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
EP0695941B1 (de) * 1994-06-08 2002-07-31 Affymetrix, Inc. Verfahren und Vorrichtung zum Verpacken von Chips
DE19605214A1 (de) 1995-02-23 1996-08-29 Bosch Gmbh Robert Ultraschallantriebselement
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5858671A (en) * 1996-11-01 1999-01-12 The University Of Iowa Research Foundation Iterative and regenerative DNA sequencing method
US5910288A (en) * 1997-07-10 1999-06-08 Hewlett-Packard Company Method and apparatus for mixing a thin film of fluid
US6309875B1 (en) * 2000-02-29 2001-10-30 Agilent Technologies, Inc. Apparatus for biomolecular array hybridization facilitated by agitation during centrifuging

Also Published As

Publication number Publication date
EP1226863B1 (de) 2004-11-03
DE60015590T2 (de) 2005-11-10
ES2232407T3 (es) 2005-06-01
DE60015590D1 (de) 2004-12-09
EP1226863A1 (de) 2002-07-31
US6872566B2 (en) 2005-03-29
US20020164619A1 (en) 2002-11-07

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