ATE384954T1 - Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe - Google Patents

Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe

Info

Publication number
ATE384954T1
ATE384954T1 AT01993160T AT01993160T ATE384954T1 AT E384954 T1 ATE384954 T1 AT E384954T1 AT 01993160 T AT01993160 T AT 01993160T AT 01993160 T AT01993160 T AT 01993160T AT E384954 T1 ATE384954 T1 AT E384954T1
Authority
AT
Austria
Prior art keywords
gene induction
biological sample
blocking agent
sample
collecting
Prior art date
Application number
AT01993160T
Other languages
English (en)
Inventor
Frank Augello
Helge Bastian
Uwe Oelmuller
Lynne Rainen
Matthew Walenciak
Ralf Wyrich
Original Assignee
Becton Dickinson Co
Qiagen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/707,745 external-priority patent/US6602718B1/en
Application filed by Becton Dickinson Co, Qiagen Gmbh filed Critical Becton Dickinson Co
Application granted granted Critical
Publication of ATE384954T1 publication Critical patent/ATE384954T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
AT01993160T 2000-11-08 2001-11-07 Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe ATE384954T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/707,745 US6602718B1 (en) 2000-11-08 2000-11-08 Method and device for collecting and stabilizing a biological sample
US09/984,658 US6617170B2 (en) 2000-11-08 2001-10-30 Method and device for collecting and stabilizing a biological sample

Publications (1)

Publication Number Publication Date
ATE384954T1 true ATE384954T1 (de) 2008-02-15

Family

ID=27107945

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01993160T ATE384954T1 (de) 2000-11-08 2001-11-07 Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe

Country Status (8)

Country Link
US (1) US6821789B2 (de)
EP (1) EP1356302B1 (de)
JP (1) JP5192631B2 (de)
CN (1) CN100386441C (de)
AT (1) ATE384954T1 (de)
CA (1) CA2428864C (de)
DK (1) DK1356302T3 (de)
WO (1) WO2002056030A2 (de)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391550B1 (en) 1996-09-19 2002-05-21 Affymetrix, Inc. Identification of molecular sequence signatures and methods involving the same
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
DE10006662A1 (de) * 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
ES2784011T3 (es) 2002-10-16 2020-09-21 Streck Inc Procedimiento y dispositivo para recoger y preservar las células para su análisis
US7534621B2 (en) * 2003-02-07 2009-05-19 Canon Kabuhsiki Kashia Method of producing probe medium and method of immobilizing probe using probe medium
US20040248106A1 (en) * 2003-06-06 2004-12-09 Leonard Leslie A. Clinical array assays that include a sample quality evaluation step and compositions for use in practicing the same
JP2007524844A (ja) * 2003-09-22 2007-08-30 ベクトン・ディキンソン・アンド・カンパニー デンドリマー内部標準を使用する質量分析による生体分子検体の定量化
US20080176209A1 (en) * 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
AU2005245338B2 (en) 2004-04-08 2011-11-17 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20080146790A1 (en) * 2004-08-18 2008-06-19 Daniel Grolz Additive, Method, and Article For Dna Collection, Stabilization, and Purification
US7803523B2 (en) * 2004-08-27 2010-09-28 University Health Network Whole blood preparation for cytometric analysis of cell signaling pathways
EP1809351A2 (de) * 2004-09-28 2007-07-25 Mallinckrodt, Inc. Behälter mit eingezwängtem erhaltungsmittel
US20060094023A1 (en) * 2004-11-02 2006-05-04 Industrial Technology Research Institute Method for isolating nucleic acid by using amino surfactants
TWI294460B (en) * 2004-12-23 2008-03-11 Ind Tech Res Inst Method for stabilizing nucleic acids
US7608457B2 (en) * 2005-03-10 2009-10-27 Streck, Inc. Blood collection and testing improvements
US7419832B2 (en) * 2005-03-10 2008-09-02 Streck, Inc. Blood collection tube with surfactant
DE102005013261A1 (de) * 2005-03-22 2006-09-28 Adnagen Ag Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen
DE102005015005A1 (de) 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
EP1915447A4 (de) * 2005-08-19 2008-07-30 Bioventures Inc Verfahren und vorrichtung zum sammeln und isolieren von nukleinsäuren
FR2895993A1 (fr) * 2006-01-10 2007-07-13 Immunid Sarl Composition pour la stabilisation d'echantillons biologiques et procede de stabilisation
US20070190526A1 (en) * 2006-02-16 2007-08-16 Nexgen Diagnostics Llc Methods of extracting nucleic acids
US7748283B2 (en) * 2007-02-16 2010-07-06 Whatman, Inc. Controlled transfer biological sample collection devices and methods of using such devices
MX2009009994A (es) 2007-03-20 2009-10-19 Becton Dickinson Co Ensayos que usan particulas activas para espectroscopia raman mejorada por superficie (sers).
EP2214824A4 (de) * 2007-11-28 2015-08-19 Smart Tube Inc Vorrichtungen, systeme und verfahren zur entnahme, stimulation, stabilisierung und analyse einer biologischen probe
EP2249701B1 (de) 2008-03-05 2020-04-29 Becton, Dickinson and Company Sammelbehälteranordnung mit kapillarwirkung
MX2010009668A (es) 2008-03-05 2010-10-15 Becton Dickinson Co Tapon perforable comoldeado y metodo para hacerlo.
JP5674664B2 (ja) * 2008-09-04 2015-02-25 ベックマン コールター， インコーポレイテッド パンキナーゼ活性化およびシグナリング経路の評価
US20100093551A1 (en) * 2008-10-09 2010-04-15 Decision Biomarkers, Inc. Liquid Transfer and Filter System
CN102186590A (zh) * 2008-10-17 2011-09-14 布鲁塞尔自由大学 用于用试剂使生物样品脉动和稳定如此脉动的样品的装置、试剂盒和方法
DE202010018561U1 (de) 2009-01-21 2017-08-28 Streck Inc. Blutsammelröhrchen
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
EP3290530B1 (de) 2009-02-18 2020-09-02 Streck Inc. Konservierung von zellfreien nukleinsäuren
CA2780536C (en) 2009-11-09 2018-01-02 Streck, Inc. Stabilization of rna in and extracting from intact cells within a blood sample
US10105706B2 (en) 2010-01-19 2018-10-23 Becton, Dickinson And Company Container assembly and system for detection thereof
US20110195397A1 (en) * 2010-02-10 2011-08-11 Selinfreund Richard H Drink mixture for the stabilization of diagnostic biomarkers
CN101787345B (zh) * 2010-03-10 2013-04-17 西安交通大学 一种用于细胞检查的体液样本收集、分离装置和方法
EP2388312A1 (de) 2010-05-17 2011-11-23 Curetis AG Universell anwendbarer Lysepuffer und Verarbeitungsverfahren zur Lyse von Körperproben
EP2576820A1 (de) 2010-06-02 2013-04-10 Qiagen GmbH Stabilisierung von nukleinsäuren in zellmaterial-haltigen biologischen proben
CN103069002A (zh) * 2010-07-20 2013-04-24 贝克顿·迪金森公司 用于将及时现场护理快速诊断测试结果与基于实验室的方法相连的方法
WO2012018638A2 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
WO2012018639A2 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
US8460620B2 (en) 2010-12-03 2013-06-11 Becton, Dickinson And Company Specimen collection container assembly
WO2012151391A2 (en) 2011-05-04 2012-11-08 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
CN102250876B (zh) * 2011-05-18 2014-08-13 李学敬 从生物材料中分离纯化rna的方法
CA2779850C (en) 2011-06-17 2016-08-09 Norgen Biotek Corporation Methods, reagents and kits for preservation of nucleic acids in biological samples
EP3150702B1 (de) 2011-06-19 2021-05-19 DNA Genotek, Inc. Vorrichtungen, lösungen und verfahren zur probenentnahme
DE102011080853B4 (de) 2011-08-11 2014-03-27 Axagarius Gmbh & Co. Kg Verfahren zur Isolierung von RNA aus Volblutproben
DK2742152T3 (en) * 2011-08-12 2017-07-31 Qiagen Gmbh PROCEDURE FOR ISOLATING NUCLEIC ACIDS
CN103827301A (zh) * 2011-09-13 2014-05-28 恰根有限公司 从兽医学全血样品中分离核酸的方法
US11203000B2 (en) 2011-10-20 2021-12-21 Becton, Dickinson And Company Mixing element for container assemblies
DE102012025557A1 (de) 2012-04-11 2013-10-17 Sarstedt Ag & Co. Vorrichtung zur Ent- und/oder Aufnahme von Körperflüssigkeiten, insbesondere Blut
EP2836846B1 (de) 2012-04-13 2024-04-24 Becton, Dickinson and Company Reflexprüfung von proben unter verwendung von restmaterialien aus einem vorhergehenden test
US9427707B2 (en) 2012-08-10 2016-08-30 Jean I. Montagu Filtering blood
US20150225712A1 (en) * 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
EP3249054A1 (de) 2012-12-20 2017-11-29 Biomatrica, INC. Formulierungen und verfahren zur stabilisierung von pcr-reagenzien
GB201303666D0 (en) * 2013-03-01 2013-04-17 Goldsborough Andrew S Sample fixation and stabilisation
EP4136972A1 (de) 2013-07-24 2023-02-22 Streck, Inc. Zusammensetzungen und verfahren zur stabilisierung zirkulierender tumorzellen
CN103789202B (zh) * 2014-01-26 2017-10-24 付士明 常温保存核酸的采集容器
WO2015160595A1 (en) * 2014-04-14 2015-10-22 Abbott Molecular, Inc. Medium used for blood sample collection and transport
WO2015191632A1 (en) 2014-06-10 2015-12-17 Biomatrica, Inc. Stabilization of thrombocytes at ambient temperatures
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
CN105158455B (zh) * 2015-09-17 2018-10-16 深圳市钠科生物有限公司 一种提高样品检测精度和准确性的生物样品采集方法、装置、系统、生物样品稳定试剂及应用
JP2017099376A (ja) * 2015-11-19 2017-06-08 株式会社日吉 環境水試料の前処理方法、環境水試料の前処理剤、並びに、生物相又は生物の量の推定方法
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
KR102589056B1 (ko) 2015-12-08 2023-10-12 바이오매트리카 인코포레이티드 적혈구 침강 속도의 감소
ES2694285T3 (es) 2016-02-11 2018-12-19 Sarstedt Ag & Co. Kg Dispositivo y procedimiento para el aislamiento de ácidos nucleicos de sangre entera
KR20220139426A (ko) * 2016-03-31 2022-10-14 버클리 라잇츠, 인크. 핵산 안정화 시약, 키트들, 및 그 이용 방법들
CN109153992B (zh) 2016-05-27 2022-11-29 诺根生物科技公司 生物样本中游离核酸的保存
AU2017274602A1 (en) 2016-05-31 2018-12-20 Dna Genotek Inc. A composition, system and method for removal of detergents from aqueous solutions
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
CN108333346B (zh) * 2017-01-19 2021-07-06 深圳市新产业生物医学工程股份有限公司 dsDNA免疫磁性微球体系、其制备方法和应用以及保存液
CN110636903A (zh) * 2017-01-30 2019-12-31 保障生物系统控股有限公司 用于从微生物中提取脱氧核糖核酸和/或核糖核酸的珠粒撞击管和方法
CN110997933B (zh) * 2017-08-02 2024-01-09 萨斯特德特股份有限两合公司 用于稳定无细胞核酸和细胞的方法和组合物
US12378543B2 (en) 2017-10-19 2025-08-05 Streck Llc Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles
CN111492223B (zh) * 2017-12-29 2023-07-25 豪夫迈·罗氏有限公司 组织样品制备系统
US20210235688A1 (en) * 2018-04-19 2021-08-05 Board Of Regents, The University Of Texas System Methods for measuring and stabilizing stat3 inhibitors
CN109090104A (zh) * 2018-09-27 2018-12-28 广州新诚生物科技有限公司 保存液及其制备方法和应用
CN109486904A (zh) * 2018-12-29 2019-03-19 广州阳普医疗科技股份有限公司 一种全血rna保存液及其应用
WO2021130415A1 (en) * 2019-12-23 2021-07-01 Biopsense Oy Method, automated system and cartridge for extraction of cell-free nucleic acids from a blood sample
US20230358759A1 (en) * 2022-05-04 2023-11-09 Creative Medical Technologies, Inc. Cytokine based assessment of recipient ability to respond to stem cell therapy for cartilage regeneration
GB2623570B (en) * 2022-10-21 2025-07-23 Wobble Genomics Ltd Method and products for biomarker identification

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3847738A (en) 1971-11-01 1974-11-12 American Hospital Supply Corp Blood collection and preservation unit
JPS6360931A (ja) 1986-08-29 1988-03-17 Noboru Sato 血液または血液製剤保存液およびこれを用いた血液または血液製剤の保存方法
US5010183A (en) * 1989-07-07 1991-04-23 Macfarlane Donald E Process for purifying DNA and RNA using cationic detergents
DE4034036C2 (de) 1990-10-26 1994-03-03 Diagen Inst Molekularbio Vorrichtung und Verfahren zur Isolierung von Nukleinsäuren aus Zellsuspensionen
US5459253A (en) 1991-07-19 1995-10-17 Pharmacia P-L Biochemicals Inc. M-RNA purification
US5300635A (en) 1993-02-01 1994-04-05 University Of Iowa Research Foundation Quaternary amine surfactants and methods of using same in isolation of nucleic acids
AU6230594A (en) * 1993-02-01 1994-08-29 University Of Iowa Research Foundation, The Quartenary amine surfactants and methods of using same in isolation of rna
US5906744A (en) 1997-04-30 1999-05-25 Becton Dickinson And Company Tube for preparing a plasma specimen for diagnostic assays and method of making thereof
US5860937A (en) 1997-04-30 1999-01-19 Becton, Dickinson & Company Evacuated sample collection tube with aqueous additive
US5932422A (en) 1997-11-14 1999-08-03 Millennium Pharmaceuticals, Inc. Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase
DE19836559A1 (de) * 1998-08-12 2000-03-23 Antigen Gmbh Gefäß zur Entnahme von Blut
ATE302940T1 (de) 1999-03-04 2005-09-15 Retsch Kurt Gmbh & Co Kg Verfahren und vorrichtung zum aufschluss von biologischem material
US6916608B2 (en) 1999-09-10 2005-07-12 Becton, Dickinson And Company Composition for providing long term stability to cells for diagnostic testing
DE10031236A1 (de) * 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
US6602718B1 (en) * 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample

Also Published As

Publication number Publication date
EP1356302B1 (de) 2008-01-23
CN100386441C (zh) 2008-05-07
DK1356302T3 (da) 2008-06-02
CA2428864A1 (en) 2002-07-18
CN1503910A (zh) 2004-06-09
US6821789B2 (en) 2004-11-23
CA2428864C (en) 2011-04-12
JP2004534731A (ja) 2004-11-18
EP1356302A2 (de) 2003-10-29
WO2002056030A2 (en) 2002-07-18
JP5192631B2 (ja) 2013-05-08
US20040048384A1 (en) 2004-03-11
WO2002056030A3 (en) 2003-08-28

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