ATE384954T1 - Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe - Google Patents
Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probeInfo
- Publication number
- ATE384954T1 ATE384954T1 AT01993160T AT01993160T ATE384954T1 AT E384954 T1 ATE384954 T1 AT E384954T1 AT 01993160 T AT01993160 T AT 01993160T AT 01993160 T AT01993160 T AT 01993160T AT E384954 T1 ATE384954 T1 AT E384954T1
- Authority
- AT
- Austria
- Prior art keywords
- gene induction
- biological sample
- blocking agent
- sample
- collecting
- Prior art date
Links
- 239000012472 biological sample Substances 0.000 title abstract 4
- 230000000087 stabilizing effect Effects 0.000 title 1
- 230000006698 induction Effects 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 239000002981 blocking agent Substances 0.000 abstract 3
- 239000003599 detergent Substances 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000001767 cationic compounds Chemical class 0.000 abstract 1
- -1 cationic detergents Chemical class 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 230000003196 chaotropic effect Effects 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000003161 ribonuclease inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2525—Stabilizing or preserving
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/707,745 US6602718B1 (en) | 2000-11-08 | 2000-11-08 | Method and device for collecting and stabilizing a biological sample |
| US09/984,658 US6617170B2 (en) | 2000-11-08 | 2001-10-30 | Method and device for collecting and stabilizing a biological sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE384954T1 true ATE384954T1 (de) | 2008-02-15 |
Family
ID=27107945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01993160T ATE384954T1 (de) | 2000-11-08 | 2001-11-07 | Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6821789B2 (de) |
| EP (1) | EP1356302B1 (de) |
| JP (1) | JP5192631B2 (de) |
| CN (1) | CN100386441C (de) |
| AT (1) | ATE384954T1 (de) |
| CA (1) | CA2428864C (de) |
| DK (1) | DK1356302T3 (de) |
| WO (1) | WO2002056030A2 (de) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6391550B1 (en) | 1996-09-19 | 2002-05-21 | Affymetrix, Inc. | Identification of molecular sequence signatures and methods involving the same |
| US20080064108A1 (en) * | 1997-12-10 | 2008-03-13 | Tony Baker | Urine Preservation System |
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| DE10006662A1 (de) * | 2000-02-15 | 2001-08-23 | Antigen Produktions Gmbh | Gefäß zur Nukleinsäureanalytik |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| CA2445204C (en) | 2002-10-16 | 2014-08-12 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
| US7534621B2 (en) * | 2003-02-07 | 2009-05-19 | Canon Kabuhsiki Kashia | Method of producing probe medium and method of immobilizing probe using probe medium |
| US20040248106A1 (en) * | 2003-06-06 | 2004-12-09 | Leonard Leslie A. | Clinical array assays that include a sample quality evaluation step and compositions for use in practicing the same |
| JP2007524844A (ja) * | 2003-09-22 | 2007-08-30 | ベクトン・ディキンソン・アンド・カンパニー | デンドリマー内部標準を使用する質量分析による生体分子検体の定量化 |
| US20080176209A1 (en) * | 2004-04-08 | 2008-07-24 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| WO2005113147A2 (en) | 2004-04-08 | 2005-12-01 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| AU2005277527A1 (en) * | 2004-08-18 | 2006-03-02 | Preanalytix Gmbh | Additive, method, and article for DNA collection, stabilization, and purification |
| US7803523B2 (en) * | 2004-08-27 | 2010-09-28 | University Health Network | Whole blood preparation for cytometric analysis of cell signaling pathways |
| WO2006037124A2 (en) * | 2004-09-28 | 2006-04-06 | Mallinckrodt Inc. | Container with constrained quality maintenance agent |
| TWI294460B (en) * | 2004-12-23 | 2008-03-11 | Ind Tech Res Inst | Method for stabilizing nucleic acids |
| US20060094023A1 (en) * | 2004-11-02 | 2006-05-04 | Industrial Technology Research Institute | Method for isolating nucleic acid by using amino surfactants |
| US7419832B2 (en) * | 2005-03-10 | 2008-09-02 | Streck, Inc. | Blood collection tube with surfactant |
| US7608457B2 (en) * | 2005-03-10 | 2009-10-27 | Streck, Inc. | Blood collection and testing improvements |
| DE102005013261A1 (de) * | 2005-03-22 | 2006-09-28 | Adnagen Ag | Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen |
| DE102005015005A1 (de) * | 2005-04-01 | 2006-10-05 | Qiagen Gmbh | Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe |
| WO2007022483A2 (en) * | 2005-08-19 | 2007-02-22 | Bioventures, Inc. | Method and device for the collection and isolation of nucleic acid |
| FR2895993A1 (fr) * | 2006-01-10 | 2007-07-13 | Immunid Sarl | Composition pour la stabilisation d'echantillons biologiques et procede de stabilisation |
| US20070190526A1 (en) * | 2006-02-16 | 2007-08-16 | Nexgen Diagnostics Llc | Methods of extracting nucleic acids |
| US7748283B2 (en) * | 2007-02-16 | 2010-07-06 | Whatman, Inc. | Controlled transfer biological sample collection devices and methods of using such devices |
| WO2008116093A2 (en) | 2007-03-20 | 2008-09-25 | Becton, Dickinson And Company | Assays using surface-enhanced raman spectroscopy (sers)-active particles |
| EP2214824A4 (de) * | 2007-11-28 | 2015-08-19 | Smart Tube Inc | Vorrichtungen, systeme und verfahren zur entnahme, stimulation, stabilisierung und analyse einer biologischen probe |
| CA2717894C (en) | 2008-03-05 | 2014-05-27 | Becton, Dickinson And Company | Capillary action collection device and container assembly |
| CA2718060C (en) | 2008-03-05 | 2015-08-04 | Becton, Dickinson & Company | Co-molded pierceable stopper and method for making same |
| CN102144161B (zh) | 2008-09-04 | 2016-02-17 | 贝克曼考尔特公司 | 泛激酶活化与信号通路的评估 |
| US20100093551A1 (en) * | 2008-10-09 | 2010-04-15 | Decision Biomarkers, Inc. | Liquid Transfer and Filter System |
| WO2010043271A1 (en) * | 2008-10-17 | 2010-04-22 | Universite Libre De Bruxelles | Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed |
| DE202010018561U1 (de) | 2009-01-21 | 2017-08-28 | Streck Inc. | Blutsammelröhrchen |
| US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| NO2398912T3 (de) | 2009-02-18 | 2018-02-10 | ||
| US20110111410A1 (en) | 2009-11-09 | 2011-05-12 | Streck, Inc. | Stabilization of rna in intact cells within a blood sample |
| WO2011091013A1 (en) | 2010-01-19 | 2011-07-28 | Becton, Dickinson And Company | Container assembly and system for detection thereof |
| US20110195488A1 (en) * | 2010-02-10 | 2011-08-11 | Selinfreund Richard H | Devices for collection and stabilization of biomarkers in liquid samples |
| CN101787345B (zh) * | 2010-03-10 | 2013-04-17 | 西安交通大学 | 一种用于细胞检查的体液样本收集、分离装置和方法 |
| EP2388312A1 (de) | 2010-05-17 | 2011-11-23 | Curetis AG | Universell anwendbarer Lysepuffer und Verarbeitungsverfahren zur Lyse von Körperproben |
| US20130137586A1 (en) | 2010-06-02 | 2013-05-30 | Qiagen Gmbh | Stabilization of nucleic acids in cell material-containing biological samples |
| WO2012012527A2 (en) * | 2010-07-20 | 2012-01-26 | Becton, Dickinson And Company | Method for linking point of care rapid diagnostic testing results to laboratory-based methods |
| EP2598660B1 (de) | 2010-07-26 | 2017-03-15 | Biomatrica, INC. | Zusammensetzungen zur stabilisierung von dna, rna und proteinen in blut- und anderen biologischen proben während des transports und der lagerung bei umgebungstemperaturen |
| WO2012018639A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| US8460620B2 (en) | 2010-12-03 | 2013-06-11 | Becton, Dickinson And Company | Specimen collection container assembly |
| US9956281B2 (en) | 2011-05-04 | 2018-05-01 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| CN102250876B (zh) * | 2011-05-18 | 2014-08-13 | 李学敬 | 从生物材料中分离纯化rna的方法 |
| CA2779850C (en) | 2011-06-17 | 2016-08-09 | Norgen Biotek Corporation | Methods, reagents and kits for preservation of nucleic acids in biological samples |
| WO2012177656A2 (en) | 2011-06-19 | 2012-12-27 | Abogen, Inc. | Devices, solutions and methods for sample collection |
| DE102011080853B4 (de) | 2011-08-11 | 2014-03-27 | Axagarius Gmbh & Co. Kg | Verfahren zur Isolierung von RNA aus Volblutproben |
| EP3789500A1 (de) * | 2011-08-12 | 2021-03-10 | QIAGEN GmbH | Verfahren zur isolierung von nukleinsäuren |
| WO2013037401A1 (en) * | 2011-09-13 | 2013-03-21 | Qiagen Gmbh | Method for isolating nucleic acids from a veterinary whole blood sample |
| JP6027125B2 (ja) | 2011-10-20 | 2016-11-16 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 容器アセンブリ用の混合要素 |
| DE102012025557A1 (de) | 2012-04-11 | 2013-10-17 | Sarstedt Ag & Co. | Vorrichtung zur Ent- und/oder Aufnahme von Körperflüssigkeiten, insbesondere Blut |
| AU2013246418B2 (en) | 2012-04-13 | 2017-02-23 | Becton, Dickinson And Company | Reflex testing of samples using residual materials from a prior test |
| US9427707B2 (en) | 2012-08-10 | 2016-08-30 | Jean I. Montagu | Filtering blood |
| EP2888363B1 (de) * | 2012-08-21 | 2018-06-06 | Qiagen GmbH | Verfahren zur isolierung von nukleinsäuren aus einer stabilisierten probe mit formaldehydfreigabe |
| US9725703B2 (en) | 2012-12-20 | 2017-08-08 | Biomatrica, Inc. | Formulations and methods for stabilizing PCR reagents |
| GB201303666D0 (en) | 2013-03-01 | 2013-04-17 | Goldsborough Andrew S | Sample fixation and stabilisation |
| US10091984B2 (en) | 2013-07-24 | 2018-10-09 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
| CN103789202B (zh) * | 2014-01-26 | 2017-10-24 | 付士明 | 常温保存核酸的采集容器 |
| CN106461514B (zh) * | 2014-04-14 | 2020-01-21 | 雅培分子公司 | 用于血液样品收集和运输的介质 |
| ES2786373T3 (es) | 2014-06-10 | 2020-10-09 | Biomatrica Inc | Estabilización de trombocitos a temperaturas ambiente |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| CN105158455B (zh) * | 2015-09-17 | 2018-10-16 | 深圳市钠科生物有限公司 | 一种提高样品检测精度和准确性的生物样品采集方法、装置、系统、生物样品稳定试剂及应用 |
| JP2017099376A (ja) * | 2015-11-19 | 2017-06-08 | 株式会社日吉 | 環境水試料の前処理方法、環境水試料の前処理剤、並びに、生物相又は生物の量の推定方法 |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| KR20250047404A (ko) | 2015-12-08 | 2025-04-03 | 바이오매트리카 인코포레이티드 | 적혈구 침강 속도의 감소 |
| ES2694285T3 (es) | 2016-02-11 | 2018-12-19 | Sarstedt Ag & Co. Kg | Dispositivo y procedimiento para el aislamiento de ácidos nucleicos de sangre entera |
| JP7019590B2 (ja) | 2016-03-31 | 2022-02-15 | バークレー ライツ,インコーポレイテッド | 核酸安定化試薬、キット、及びその使用方法 |
| CN109153992B (zh) | 2016-05-27 | 2022-11-29 | 诺根生物科技公司 | 生物样本中游离核酸的保存 |
| EP3464589A4 (de) * | 2016-05-31 | 2020-02-26 | DNA Genotek Inc. | Zusammensetzung, system und verfahren zur entfernung von detergenzien aus wässrigen lösungen |
| WO2018022991A1 (en) | 2016-07-29 | 2018-02-01 | Streck, Inc. | Suspension composition for hematology analysis control |
| CN108333346B (zh) * | 2017-01-19 | 2021-07-06 | 深圳市新产业生物医学工程股份有限公司 | dsDNA免疫磁性微球体系、其制备方法和应用以及保存液 |
| BR112019015034A2 (pt) * | 2017-01-30 | 2020-03-10 | Safeguard Biosystems Holdings Ltd. | Tubo de batimento de microesfera e método para extração de ácido desoxirribonucleico e/ou ácido ribonucleico a partir de micro-organismos |
| BR112020001091A2 (pt) | 2017-08-02 | 2020-09-15 | Sarstedt Ag & Co. Kg | processo e composição para a estabilização de ácidos nucleicos livres de células |
| CN115119829B (zh) | 2017-10-19 | 2024-07-12 | 斯特雷克股份有限公司 | 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物 |
| WO2019129646A1 (en) | 2017-12-29 | 2019-07-04 | F. Hoffmann-La Roche Ag | Tissue sample preparation system |
| WO2019204427A1 (en) * | 2018-04-19 | 2019-10-24 | Tweardy David J | Methods for measuring and stabilizing stat3 inhibitors |
| CN109090104A (zh) * | 2018-09-27 | 2018-12-28 | 广州新诚生物科技有限公司 | 保存液及其制备方法和应用 |
| CN109486904A (zh) * | 2018-12-29 | 2019-03-19 | 广州阳普医疗科技股份有限公司 | 一种全血rna保存液及其应用 |
| US20230028621A1 (en) * | 2019-12-23 | 2023-01-26 | Biopsense Oy | Method, automated system and cartridge for extraction of cell-free nucleic acids from a blood sample |
| US20230358759A1 (en) * | 2022-05-04 | 2023-11-09 | Creative Medical Technologies, Inc. | Cytokine based assessment of recipient ability to respond to stem cell therapy for cartilage regeneration |
| GB2623570B (en) * | 2022-10-21 | 2025-07-23 | Wobble Genomics Ltd | Method and products for biomarker identification |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3847738A (en) | 1971-11-01 | 1974-11-12 | American Hospital Supply Corp | Blood collection and preservation unit |
| JPS6360931A (ja) | 1986-08-29 | 1988-03-17 | Noboru Sato | 血液または血液製剤保存液およびこれを用いた血液または血液製剤の保存方法 |
| US5010183A (en) * | 1989-07-07 | 1991-04-23 | Macfarlane Donald E | Process for purifying DNA and RNA using cationic detergents |
| DE4034036C2 (de) | 1990-10-26 | 1994-03-03 | Diagen Inst Molekularbio | Vorrichtung und Verfahren zur Isolierung von Nukleinsäuren aus Zellsuspensionen |
| US5459253A (en) | 1991-07-19 | 1995-10-17 | Pharmacia P-L Biochemicals Inc. | M-RNA purification |
| US5300635A (en) | 1993-02-01 | 1994-04-05 | University Of Iowa Research Foundation | Quaternary amine surfactants and methods of using same in isolation of nucleic acids |
| AU6230594A (en) * | 1993-02-01 | 1994-08-29 | University Of Iowa Research Foundation, The | Quartenary amine surfactants and methods of using same in isolation of rna |
| US5860937A (en) | 1997-04-30 | 1999-01-19 | Becton, Dickinson & Company | Evacuated sample collection tube with aqueous additive |
| US5906744A (en) | 1997-04-30 | 1999-05-25 | Becton Dickinson And Company | Tube for preparing a plasma specimen for diagnostic assays and method of making thereof |
| US5932422A (en) | 1997-11-14 | 1999-08-03 | Millennium Pharmaceuticals, Inc. | Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase |
| DE19836559A1 (de) * | 1998-08-12 | 2000-03-23 | Antigen Gmbh | Gefäß zur Entnahme von Blut |
| ATE302940T1 (de) | 1999-03-04 | 2005-09-15 | Retsch Kurt Gmbh & Co Kg | Verfahren und vorrichtung zum aufschluss von biologischem material |
| US6916608B2 (en) | 1999-09-10 | 2005-07-12 | Becton, Dickinson And Company | Composition for providing long term stability to cells for diagnostic testing |
| DE10031236A1 (de) * | 2000-06-27 | 2002-01-10 | Qiagen Gmbh | Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien |
| US6602718B1 (en) * | 2000-11-08 | 2003-08-05 | Becton, Dickinson And Company | Method and device for collecting and stabilizing a biological sample |
-
2001
- 2001-11-07 CN CNB018216633A patent/CN100386441C/zh not_active Expired - Lifetime
- 2001-11-07 JP JP2002556234A patent/JP5192631B2/ja not_active Expired - Lifetime
- 2001-11-07 AT AT01993160T patent/ATE384954T1/de active
- 2001-11-07 WO PCT/US2001/042998 patent/WO2002056030A2/en not_active Ceased
- 2001-11-07 EP EP01993160A patent/EP1356302B1/de not_active Expired - Lifetime
- 2001-11-07 CA CA2428864A patent/CA2428864C/en not_active Expired - Lifetime
- 2001-11-07 DK DK01993160T patent/DK1356302T3/da active
-
2003
- 2003-07-02 US US10/610,554 patent/US6821789B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6821789B2 (en) | 2004-11-23 |
| CA2428864A1 (en) | 2002-07-18 |
| JP2004534731A (ja) | 2004-11-18 |
| JP5192631B2 (ja) | 2013-05-08 |
| WO2002056030A2 (en) | 2002-07-18 |
| EP1356302A2 (de) | 2003-10-29 |
| EP1356302B1 (de) | 2008-01-23 |
| CN1503910A (zh) | 2004-06-09 |
| DK1356302T3 (da) | 2008-06-02 |
| CN100386441C (zh) | 2008-05-07 |
| WO2002056030A3 (en) | 2003-08-28 |
| CA2428864C (en) | 2011-04-12 |
| US20040048384A1 (en) | 2004-03-11 |
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