ATE281649T1 - Nachweis und bestimmung von stufen der coronaren arterienerkrankung - Google Patents
Nachweis und bestimmung von stufen der coronaren arterienerkrankungInfo
- Publication number
- ATE281649T1 ATE281649T1 AT99944731T AT99944731T ATE281649T1 AT E281649 T1 ATE281649 T1 AT E281649T1 AT 99944731 T AT99944731 T AT 99944731T AT 99944731 T AT99944731 T AT 99944731T AT E281649 T1 ATE281649 T1 AT E281649T1
- Authority
- AT
- Austria
- Prior art keywords
- sample
- clinically significant
- patient
- marker
- testing
- Prior art date
Links
- 208000029078 coronary artery disease Diseases 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 239000003550 marker Substances 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 230000000923 atherogenic effect Effects 0.000 abstract 2
- 210000002540 macrophage Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000014452 scavenger receptors Human genes 0.000 abstract 2
- 108010078070 scavenger receptors Proteins 0.000 abstract 2
- 102000000853 LDL receptors Human genes 0.000 abstract 1
- 108010001831 LDL receptors Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/323—Arteriosclerosis, Stenosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/809—Multifield plates or multicontainer arrays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/819—Multifunctional antigen or antibody
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/148,158 US6309888B1 (en) | 1998-09-04 | 1998-09-04 | Detection and determination of the stages of coronary artery disease |
| PCT/IB1999/001596 WO2000014548A1 (en) | 1998-09-04 | 1999-08-31 | Detection and determination of the stages of coronary artery disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE281649T1 true ATE281649T1 (de) | 2004-11-15 |
Family
ID=22524551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99944731T ATE281649T1 (de) | 1998-09-04 | 1999-08-31 | Nachweis und bestimmung von stufen der coronaren arterienerkrankung |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US6309888B1 (de) |
| EP (2) | EP1110092B1 (de) |
| AT (1) | ATE281649T1 (de) |
| AU (1) | AU5754699A (de) |
| CA (1) | CA2342365C (de) |
| DE (1) | DE69921668T2 (de) |
| ES (1) | ES2228098T3 (de) |
| WO (1) | WO2000014548A1 (de) |
Families Citing this family (81)
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|---|---|---|---|---|
| US6727102B1 (en) | 1997-06-20 | 2004-04-27 | Leuven Research & Development Vzw | Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins |
| US6309888B1 (en) * | 1998-09-04 | 2001-10-30 | Leuven Research & Development Vzw | Detection and determination of the stages of coronary artery disease |
| US20050197283A1 (en) * | 1998-10-04 | 2005-09-08 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease |
| IL126447A (en) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| US20030077668A1 (en) * | 1999-07-22 | 2003-04-24 | Ikagaku Co., Ltd. | Method for arteriosclerosis diagnosis |
| GB0001089D0 (en) * | 2000-01-18 | 2000-03-08 | Council Cent Lab Res Councils | Lipoprotein assay |
| NZ521534A (en) * | 2000-02-23 | 2004-10-29 | Besst Test Aps | Method for correlating blood coagulation activity with markers in urine |
| US6596544B1 (en) * | 2000-03-31 | 2003-07-22 | The Regents Of The University Of California | Functional assay of high-density lipoprotein |
| US7250304B2 (en) * | 2000-03-31 | 2007-07-31 | The Regents Of The University Of California | Functional assay of high-density lipoprotein |
| GB0027309D0 (en) * | 2000-11-08 | 2000-12-27 | Barts And The London Nat Healt | Method of measuring measuring platlet activation |
| WO2002041827A2 (en) | 2000-11-24 | 2002-05-30 | Vascular Biogenics Ltd. | Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis |
| BE1013881A6 (fr) * | 2000-12-21 | 2002-11-05 | Univ Bruxelles | Fractions de ldl oxydees, procede d'obtention et utilisation a but diagnostique ou therapeutique. |
| US20040126767A1 (en) * | 2002-12-27 | 2004-07-01 | Biosite Incorporated | Method and system for disease detection using marker combinations |
| US20040253637A1 (en) * | 2001-04-13 | 2004-12-16 | Biosite Incorporated | Markers for differential diagnosis and methods of use thereof |
| US20040203083A1 (en) * | 2001-04-13 | 2004-10-14 | Biosite, Inc. | Use of thrombus precursor protein and monocyte chemoattractant protein as diagnostic and prognostic indicators in vascular diseases |
| US7632647B2 (en) * | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
| US7713705B2 (en) * | 2002-12-24 | 2010-05-11 | Biosite, Inc. | Markers for differential diagnosis and methods of use thereof |
| US20030199000A1 (en) * | 2001-08-20 | 2003-10-23 | Valkirs Gunars E. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
| US7524635B2 (en) * | 2003-04-17 | 2009-04-28 | Biosite Incorporated | Methods and compositions for measuring natriuretic peptides and uses thereof |
| US20040176914A1 (en) * | 2001-04-13 | 2004-09-09 | Biosite Incorporated | Methods and compositions for measuring biologically active natriuretic peptides and for improving their therapeutic potential |
| US20030219734A1 (en) * | 2001-04-13 | 2003-11-27 | Biosite Incorporated | Polypeptides related to natriuretic peptides and methods of their identification and use |
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| US20040142496A1 (en) * | 2001-04-23 | 2004-07-22 | Nicholson Jeremy Kirk | Methods for analysis of spectral data and their applications: atherosclerosis/coronary heart disease |
| EP1322957B1 (de) * | 2001-05-04 | 2009-08-12 | Biosite Incorporated | Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs |
| US20040209307A1 (en) * | 2001-08-20 | 2004-10-21 | Biosite Incorporated | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
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| US7476551B2 (en) * | 2001-08-27 | 2009-01-13 | The Board Of Trustees Of The University Of Arkansas | Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels |
| DK3072978T3 (en) | 2002-05-09 | 2018-09-17 | Brigham & Womens Hospital Inc | : 1L1RL-1 AS A CARDIOVASCULAR DISEASE MARKER |
| JP5179011B2 (ja) * | 2002-10-09 | 2013-04-10 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | 胎盤虚血および多臓器不全のモニタリング |
| KR20050084845A (ko) * | 2002-10-11 | 2005-08-29 | 치엔 민 성 | 탄소질 열 확산기 및 관련 방법 |
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| US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
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| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
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| CN114533264A (zh) * | 2022-01-25 | 2022-05-27 | 中山大学孙逸仙纪念医院 | 一种无症状性冠脉疾病的预测模型训练方法、装置及系统 |
| KR20250173600A (ko) | 2023-03-17 | 2025-12-10 | 옥시토프 파마 비.브이. | 항-포스포콜린 항체 및 그 사용 방법 |
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-
1998
- 1998-09-04 US US09/148,158 patent/US6309888B1/en not_active Expired - Lifetime
-
1999
- 1999-08-31 ES ES99944731T patent/ES2228098T3/es not_active Expired - Lifetime
- 1999-08-31 AT AT99944731T patent/ATE281649T1/de not_active IP Right Cessation
- 1999-08-31 AU AU57546/99A patent/AU5754699A/en not_active Abandoned
- 1999-08-31 CA CA002342365A patent/CA2342365C/en not_active Expired - Fee Related
- 1999-08-31 DE DE69921668T patent/DE69921668T2/de not_active Expired - Lifetime
- 1999-08-31 EP EP99944731A patent/EP1110092B1/de not_active Expired - Lifetime
- 1999-08-31 WO PCT/IB1999/001596 patent/WO2000014548A1/en not_active Ceased
- 1999-08-31 EP EP04077760A patent/EP1503213A3/de not_active Withdrawn
-
2001
- 2001-07-16 US US09/906,560 patent/US20010049112A1/en not_active Abandoned
-
2002
- 2002-06-18 US US10/174,797 patent/US7166469B2/en not_active Expired - Lifetime
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2007
- 2007-01-16 US US11/654,097 patent/US7604952B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2342365A1 (en) | 2000-03-16 |
| US20030013127A1 (en) | 2003-01-16 |
| AU5754699A (en) | 2000-03-27 |
| EP1110092B1 (de) | 2004-11-03 |
| DE69921668D1 (de) | 2004-12-09 |
| US7604952B2 (en) | 2009-10-20 |
| US7166469B2 (en) | 2007-01-23 |
| EP1503213A2 (de) | 2005-02-02 |
| DE69921668T2 (de) | 2005-12-01 |
| WO2000014548A1 (en) | 2000-03-16 |
| US6309888B1 (en) | 2001-10-30 |
| EP1110092A1 (de) | 2001-06-27 |
| EP1503213A3 (de) | 2005-07-13 |
| CA2342365C (en) | 2008-05-06 |
| US20070190586A1 (en) | 2007-08-16 |
| US20010049112A1 (en) | 2001-12-06 |
| ES2228098T3 (es) | 2005-04-01 |
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