ATE283368T1 - Für die glutamatabhängigen chloridkanäle kodierende dna - Google Patents

Für die glutamatabhängigen chloridkanäle kodierende dna

Info

Publication number
ATE283368T1
ATE283368T1 AT95920633T AT95920633T ATE283368T1 AT E283368 T1 ATE283368 T1 AT E283368T1 AT 95920633 T AT95920633 T AT 95920633T AT 95920633 T AT95920633 T AT 95920633T AT E283368 T1 ATE283368 T1 AT E283368T1
Authority
AT
Austria
Prior art keywords
host cells
glutamatate
chloride channels
recombinant host
dna coding
Prior art date
Application number
AT95920633T
Other languages
English (en)
Inventor
Doris F Cully
Joseph P Arena
Ken K Liu
Demetrios Vassilatis
Original Assignee
Merck & Co Inc
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc, Univ Columbia filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE283368T1 publication Critical patent/ATE283368T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT95920633T 1994-05-25 1995-05-19 Für die glutamatabhängigen chloridkanäle kodierende dna ATE283368T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/249,112 US5527703A (en) 1994-05-25 1994-05-25 DNA encoding glutamate gated chloride channels
PCT/US1995/006556 WO1995032302A1 (en) 1994-05-25 1995-05-19 Dna encoding glutamate gated chloride channels

Publications (1)

Publication Number Publication Date
ATE283368T1 true ATE283368T1 (de) 2004-12-15

Family

ID=22942110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95920633T ATE283368T1 (de) 1994-05-25 1995-05-19 Für die glutamatabhängigen chloridkanäle kodierende dna

Country Status (8)

Country Link
US (1) US5527703A (de)
EP (1) EP0760864B1 (de)
JP (1) JP3623798B2 (de)
AT (1) ATE283368T1 (de)
CA (1) CA2191063C (de)
DE (1) DE69533796T2 (de)
ES (1) ES2232822T3 (de)
WO (1) WO1995032302A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276662B1 (it) * 1995-04-04 1997-11-03 Uni Degli Studi Camerino Vaccini polinucleotidici
US5693492A (en) * 1995-05-05 1997-12-02 Merck & Co., Inc. DNA encoding glutamate gated chloride channels
US5854411A (en) * 1997-01-09 1998-12-29 Incyte Pharmaceuticals, Inc. Human chloride channel
US6358701B1 (en) 1997-08-11 2002-03-19 Merck & Co., Inc. DNA molecules encoding Ctenocephalides felis glutamate gated chloride channels
US6048692A (en) * 1997-10-07 2000-04-11 Motorola, Inc. Sensors for electrically sensing binding events for supported molecular receptors
US20040002079A1 (en) * 1998-02-11 2004-01-01 Gunn Robert B. Sodium-phosphate cotransporter in lithium therapy for the treatment of mental illness
US7033789B1 (en) 1999-10-22 2006-04-25 Merck & Co., Inc. DNA molecules encoding L-glutamate-gated chloride channels from Schistocerca americana
JP4769401B2 (ja) * 2000-03-02 2011-09-07 メルク・シャープ・エンド・ドーム・コーポレイション Ｄｒｏｓｏｐｈｉｌａｍｅｌａｎｏｇａｓｔｅｒ中のリガンド依存性塩素イオンチャネルをコードするＤＮＡ分子
US7267964B2 (en) * 2000-03-31 2007-09-11 Merial Limited DNA molecules encoding ligand gated ion channels from Dermacentor variabilis
JP2004500119A (ja) * 2000-03-31 2004-01-08 メルク　エンド　カムパニー　インコーポレーテッド デルマセンター・ヴァリァビリスｇａｂａ依存性塩素イオンチャンネル
US6329174B1 (en) 2000-06-13 2001-12-11 Aventis Cropscience Sa Nucleic acid encoding lepidoteran glutamate-gated chloride channel
WO2003093789A2 (en) * 2002-05-01 2003-11-13 Fmc Corporation Method for measuring ion channel activity
JP7097070B2 (ja) 2015-10-01 2022-07-07 ゴレイニ インコーポレイテッド クロライドチャネルの標的発現及びその使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ240921A (en) * 1990-12-12 1994-06-27 Zymogenetics Inc G protein coupled glutamate receptor (neurotransmitters), recombinant production
US5385831A (en) * 1990-12-12 1995-01-31 Zymogenetics, Inc. Method for producing a mammalian G protein coupled glutamate receptor
WO1992019717A1 (en) * 1991-04-02 1992-11-12 Baylor College Of Medicine A high-affinity human glutamate/aspartate uptake system
GB9112504D0 (en) * 1991-06-11 1991-07-31 Merck Sharp & Dohme Cell line
WO1993007161A1 (en) * 1991-10-04 1993-04-15 Cornell Research Foundation, Inc. Molecular cloning and transformation of cyclodiene resistance
US5693492A (en) * 1995-05-05 1997-12-02 Merck & Co., Inc. DNA encoding glutamate gated chloride channels

Also Published As

Publication number Publication date
JPH10507064A (ja) 1998-07-14
DE69533796D1 (de) 2004-12-30
EP0760864B1 (de) 2004-11-24
US5527703A (en) 1996-06-18
CA2191063A1 (en) 1995-11-30
EP0760864A4 (de) 2000-02-02
DE69533796T2 (de) 2005-11-10
WO1995032302A1 (en) 1995-11-30
ES2232822T3 (es) 2005-06-01
JP3623798B2 (ja) 2005-02-23
EP0760864A1 (de) 1997-03-12
CA2191063C (en) 2010-07-20

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Legal Events

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