ATE284066T1 - Systeme und verfahren zur ausrichtung eines abgetasteten bildes - Google Patents

Systeme und verfahren zur ausrichtung eines abgetasteten bildes

Info

Publication number
ATE284066T1
ATE284066T1 AT98310131T AT98310131T ATE284066T1 AT E284066 T1 ATE284066 T1 AT E284066T1 AT 98310131 T AT98310131 T AT 98310131T AT 98310131 T AT98310131 T AT 98310131T AT E284066 T1 ATE284066 T1 AT E284066T1
Authority
AT
Austria
Prior art keywords
scanned image
image
systems
methods
alignment
Prior art date
Application number
AT98310131T
Other languages
English (en)
Inventor
Peter Fiekowsky
Dan M Bartell
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Application granted granted Critical
Publication of ATE284066T1 publication Critical patent/ATE284066T1/de

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T3/00—Geometric image transformations in the plane of the image
    • G06T3/60—Rotation of whole images or parts thereof
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/20—Image enhancement or restoration using local operators
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/70—Determining position or orientation of objects or cameras
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/20—Image preprocessing
    • G06V10/24—Aligning, centring, orientation detection or correction of the image
    • G06V10/245—Aligning, centring, orientation detection or correction of the image by locating a pattern; Special marks for positioning
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20068—Projection on vertical or horizontal image axis
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30072—Microarray; Biochip, DNA array; Well plate

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Quality & Reliability (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Multimedia (AREA)
  • Biophysics (AREA)
  • Evolutionary Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Image Processing (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Exposure Of Semiconductors, Excluding Electron Or Ion Beam Exposure (AREA)
  • Exposure And Positioning Against Photoresist Photosensitive Materials (AREA)
  • Image Analysis (AREA)
  • Registering Or Overturning Sheets (AREA)
AT98310131T 1997-12-11 1998-12-10 Systeme und verfahren zur ausrichtung eines abgetasteten bildes ATE284066T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6903297P 1997-12-11 1997-12-11
US08/996,737 US6090555A (en) 1997-12-11 1997-12-23 Scanned image alignment systems and methods

Publications (1)

Publication Number Publication Date
ATE284066T1 true ATE284066T1 (de) 2004-12-15

Family

ID=26749615

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98310131T ATE284066T1 (de) 1997-12-11 1998-12-10 Systeme und verfahren zur ausrichtung eines abgetasteten bildes

Country Status (6)

Country Link
US (5) US6090555A (de)
EP (1) EP0923050B1 (de)
JP (1) JP2000069998A (de)
AT (1) ATE284066T1 (de)
CA (1) CA2255384A1 (de)
DE (1) DE69827913T2 (de)

Families Citing this family (236)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US6741344B1 (en) * 1994-02-10 2004-05-25 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US6090555A (en) * 1997-12-11 2000-07-18 Affymetrix, Inc. Scanned image alignment systems and methods
US6251691B1 (en) 1996-04-25 2001-06-26 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US20020150909A1 (en) * 1999-02-09 2002-10-17 Stuelpnagel John R. Automated information processing in randomly ordered arrays
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US6245511B1 (en) * 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US20040111219A1 (en) * 1999-02-22 2004-06-10 Sandeep Gulati Active interferometric signal analysis in software
WO2000052646A2 (en) * 1999-03-03 2000-09-08 Molecularware, Inc. A method and apparatus for automation of laboratory experimentation
US6958225B2 (en) 1999-10-27 2005-10-25 Affymetrix, Inc. Complexity management of genomic DNA
US20050069956A1 (en) * 1999-11-22 2005-03-31 Michael Seul Color-encoding and in-situ interrogation of matrix-coupled chemical compounds
EP1557793B1 (de) * 1999-12-06 2008-06-25 Xerox Corporation Verfahren und Vorrichtung zur Registrierung, Darstellung und Dekodierung von Information zur räumlichen Registrierung
US6880755B2 (en) 1999-12-06 2005-04-19 Xerox Coporation Method and apparatus for display of spatially registered information using embedded data
US6935562B2 (en) 1999-12-06 2005-08-30 Xerox Corporation Operations on images having glyph carpets
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
AU7299301A (en) 2000-06-21 2002-01-02 Bioarray Solutions Ltd Multianalyte molecular analysis using application-specific random particle arrays
US7062092B2 (en) 2000-08-22 2006-06-13 Affymetrix, Inc. System, method, and computer software product for gain adjustment in biological microarray scanner
EP2390819A1 (de) 2000-08-22 2011-11-30 Affymetrix, Inc. System, Verfahren und Computersoftwareprodukt zur Steuerung eines biologischen Microarray-Scanners
US6965704B2 (en) * 2000-08-22 2005-11-15 Affymetrix, Inc. System, method, and computer software product for grid alignment of multiple scanned images
US20030045005A1 (en) * 2000-10-17 2003-03-06 Michael Seul Light-controlled electrokinetic assembly of particles near surfaces
US6829376B2 (en) * 2000-10-24 2004-12-07 Affymetrix, Inc. Computer software system, method, and product for scanned image alignment
US7130458B2 (en) * 2000-10-24 2006-10-31 Affymetrix, Inc. Computer software system, method, and product for scanned image alignment
US7050087B2 (en) * 2000-12-06 2006-05-23 Bioview Ltd. Data acquisition and display system and method
US20020183936A1 (en) * 2001-01-24 2002-12-05 Affymetrix, Inc. Method, system, and computer software for providing a genomic web portal
GB0102357D0 (en) * 2001-01-30 2001-03-14 Randox Lab Ltd Imaging method
US20040076957A1 (en) * 2001-02-01 2004-04-22 Tetsuhiko Yoshida Hybridized array analysis aiding method and analysis aiding service
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US20030068621A1 (en) * 2001-10-04 2003-04-10 Jonathan Briggs Method and device for producing oligonucleotide arrays
US20030087289A1 (en) * 2001-10-12 2003-05-08 Harry Zuzan Image analysis of high-density synthetic DNA microarrays
US6993173B2 (en) * 2001-10-12 2006-01-31 Duke University Methods for estimating probe cell locations in high-density synthetic DNA microarrays
ES2712173T3 (es) 2001-10-15 2019-05-09 Bioarray Solutions Ltd Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas
US20030099952A1 (en) * 2001-11-26 2003-05-29 Roland Green Microarrays with visible pattern detection
WO2003053586A1 (en) * 2001-12-19 2003-07-03 Affymetrix, Inc. Array plates and method for constructing array plates
AU2003215240A1 (en) 2002-02-14 2003-09-04 Illumina, Inc. Automated information processing in randomly ordered arrays
KR20070061926A (ko) * 2002-02-14 2007-06-14 도꾸리쯔교세이호징 가가꾸 기쥬쯔 신꼬 기꼬 마우스 정자 형성 유전자와 인간 남성 불임 관련 유전자,및 이들을 사용한 진단 시스템
US20040006431A1 (en) * 2002-03-21 2004-01-08 Affymetrix, Inc., A Corporation Organized Under The Laws Of Delaware System, method and computer software product for grid placement, alignment and analysis of images of biological probe arrays
EP1502098B1 (de) * 2002-05-03 2008-09-17 ViaLogy, LLC Verfahren zur charakterisierung der ausgangssignale eines microarrays
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
WO2004029586A1 (en) * 2002-09-27 2004-04-08 Nimblegen Systems, Inc. Microarray with hydrophobic barriers
US20040110212A1 (en) * 2002-09-30 2004-06-10 Mccormick Mark Microarrays with visual alignment marks
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US20040224332A1 (en) * 2003-01-29 2004-11-11 Affymetrix, Inc. System and method for calibration and focusing a scanner instrument using elements associated with a biological probe array
FR2854240B1 (fr) * 2003-04-23 2006-08-18 Commissariat Energie Atomique Biopuce a zones de reconnaissance et format optique independants et sa lecture flottante
EP2316973A1 (de) 2003-06-10 2011-05-04 The Trustees Of Boston University Nachweismethoden für Lungenerkrankungen
US20040259100A1 (en) 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US7558419B1 (en) 2003-08-14 2009-07-07 Brion Technologies, Inc. System and method for detecting integrated circuit pattern defects
US8131475B2 (en) 2003-09-03 2012-03-06 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Methods for identifying, diagnosing, and predicting survival of lymphomas
US7711492B2 (en) 2003-09-03 2010-05-04 The United States Of America As Represented By The Department Of Health And Human Services Methods for diagnosing lymphoma types
WO2005029705A2 (en) 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
PT1664722E (pt) 2003-09-22 2011-12-28 Bioarray Solutions Ltd Polielectrólito imobilizado à superfície com grupos funcionais múltiplos capazes de se ligarem covalentemente às biomoléculas
US7003758B2 (en) * 2003-10-07 2006-02-21 Brion Technologies, Inc. System and method for lithography simulation
EP1692298A4 (de) 2003-10-28 2008-08-13 Bioarray Solutions Ltd Optimierung der genexpressionsanalyse unter verwendung immobilisierter fängersonden
WO2005045060A2 (en) 2003-10-29 2005-05-19 Bioarray Solutions, Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
US6996476B2 (en) * 2003-11-07 2006-02-07 University Of North Carolina At Charlotte Methods and systems for gene expression array analysis
WO2005054516A2 (en) 2003-11-26 2005-06-16 Advandx, Inc. Peptide nucleic acid probes for analysis of certain staphylococcus species
US8407777B1 (en) 2003-11-26 2013-03-26 Rockstar Consortium Us Lp SOCKS tunneling for firewall traversal
US20050191682A1 (en) 2004-02-17 2005-09-01 Affymetrix, Inc. Methods for fragmenting DNA
US20050266432A1 (en) * 2004-02-26 2005-12-01 Illumina, Inc. Haplotype markers for diagnosing susceptibility to immunological conditions
US8065089B1 (en) 2004-03-30 2011-11-22 University Of North Carolina At Charlotte Methods and systems for analysis of dynamic biological pathways
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
EP1792263A2 (de) * 2004-09-02 2007-06-06 Vialogy Corporation Erkennung von interessensereignissen unter verwendung von quantenresonanzinterferometrie
EP1647600A3 (de) 2004-09-17 2006-06-28 Affymetrix, Inc. (A US Entity) Verfahren zur Kennzeichnung von biologischen Proben durch Hinzufügung von Nukleinsäre "bar-code" Markierungen
US20060073511A1 (en) 2004-10-05 2006-04-06 Affymetrix, Inc. Methods for amplifying and analyzing nucleic acids
CA2524964A1 (en) 2004-10-29 2006-04-29 Affymetrix, Inc. Automated method of manufacturing polymer arrays
US7682782B2 (en) 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
US7647186B2 (en) * 2004-12-07 2010-01-12 Illumina, Inc. Oligonucleotide ordering system
KR101138864B1 (ko) * 2005-03-08 2012-05-14 삼성전자주식회사 프라이머 및 프로브 세트를 설계하는 방법, 그에 의하여 설계된 프라이머 및 프로브 세트, 상기 세트를 포함하는 키트, 상기 방법을 컴퓨터가 수행할 수 있도록 하는 프로그램을기록한 컴퓨터 판독가능한 매체 및 상기 세트를 이용한 표적 서열의 동정 방법
JP2008537120A (ja) 2005-04-14 2008-09-11 ザ トラスティーズ オブ ボストン ユニバーシティ 分類予測を使用した肺障害についての診断
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
DK1907571T3 (en) 2005-06-15 2017-08-21 Complete Genomics Inc NUCLEIC ACID ANALYSIS USING INCIDENTAL MIXTURES OF NON-OVERLAPPING FRAGMENTS
EP4071458B1 (de) 2005-09-21 2025-11-05 Luminex Corporation Verfahren und systeme für die bilddatenverarbeitung
US7329860B2 (en) 2005-11-23 2008-02-12 Illumina, Inc. Confocal imaging methods and apparatus
US7849059B2 (en) * 2005-11-28 2010-12-07 Commvault Systems, Inc. Data classification systems and methods for organizing a metabase
US7634363B2 (en) 2005-12-07 2009-12-15 Affymetrix, Inc. Methods for high throughput genotyping
US20070161031A1 (en) * 2005-12-16 2007-07-12 The Board Of Trustees Of The Leland Stanford Junior University Functional arrays for high throughput characterization of gene expression regulatory elements
US8930496B2 (en) 2005-12-19 2015-01-06 Commvault Systems, Inc. Systems and methods of unified reconstruction in storage systems
US20200257596A1 (en) 2005-12-19 2020-08-13 Commvault Systems, Inc. Systems and methods of unified reconstruction in storage systems
US20070154923A1 (en) * 2005-12-29 2007-07-05 Affymetrix, Inc. Method for Gridding and Quality Control of Polymer Arrays
US9445025B2 (en) 2006-01-27 2016-09-13 Affymetrix, Inc. System, method, and product for imaging probe arrays with small feature sizes
US8055098B2 (en) * 2006-01-27 2011-11-08 Affymetrix, Inc. System, method, and product for imaging probe arrays with small feature sizes
JP2009529329A (ja) 2006-03-09 2009-08-20 トラスティーズ オブ ボストン ユニバーシティ 鼻腔上皮細胞の遺伝子発現プロファイルを用いた、肺疾患のための診断および予後診断の方法
US7914988B1 (en) 2006-03-31 2011-03-29 Illumina, Inc. Gene expression profiles to predict relapse of prostate cancer
JP4431549B2 (ja) * 2006-05-31 2010-03-17 株式会社日立ハイテクノロジーズ 蛍光分析装置
US8009889B2 (en) 2006-06-27 2011-08-30 Affymetrix, Inc. Feature intensity reconstruction of biological probe array
CA2660286A1 (en) 2006-08-09 2008-02-21 Homestead Clinical Corporation Organ-specific proteins and methods of their use
US9845494B2 (en) 2006-10-18 2017-12-19 Affymetrix, Inc. Enzymatic methods for genotyping on arrays
EP2092074A4 (de) 2006-11-02 2010-06-09 Univ Yale Beurteilung der befruchtungsfähigkeit von eizellen
US20080242560A1 (en) * 2006-11-21 2008-10-02 Gunderson Kevin L Methods for generating amplified nucleic acid arrays
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
EP1956553B1 (de) * 2007-02-09 2009-08-19 Agfa-Gevaert Visuelle Hervorhebung von Intervalländerungen mittels einer Zeitsubtraktionstechnik
EP1956552B1 (de) * 2007-02-09 2011-06-08 Agfa-Gevaert Visuelle Hervorhebung von Intervalländerungen mittels einer Zeitsubtraktionstechnik
DE602007002693D1 (de) * 2007-02-09 2009-11-19 Agfa Gevaert Visuelle Hervorhebung von Intervalländerungen mittels einer Zeitsubtraktionstechnik
EP2135080A4 (de) * 2007-03-08 2010-12-01 Switchgear Genomics Funktionelle arrays zur charakterisierung mit hohem durchsatz von regulatorischen elementen in nichttranslatierten bereichen von genen
US20080241831A1 (en) * 2007-03-28 2008-10-02 Jian-Bing Fan Methods for detecting small RNA species
CA2683559C (en) 2007-04-13 2019-09-24 Dana Farber Cancer Institute, Inc. Methods for treating cancer resistant to erbb therapeutics
US8200440B2 (en) * 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data
US7836174B2 (en) * 2008-01-30 2010-11-16 Commvault Systems, Inc. Systems and methods for grid-based data scanning
US8296301B2 (en) 2008-01-30 2012-10-23 Commvault Systems, Inc. Systems and methods for probabilistic data classification
WO2009098485A1 (en) * 2008-02-07 2009-08-13 Forensic Sciences Service Ltd Improvements in and relating to analysis
US9012370B2 (en) * 2008-03-11 2015-04-21 National Cancer Center Method for measuring chromosome, gene or specific nucleotide sequence copy numbers using SNP array
US8039817B2 (en) 2008-05-05 2011-10-18 Illumina, Inc. Compensator for multiple surface imaging
US20110105356A1 (en) * 2008-05-07 2011-05-05 Derosier Chad F Compositions and methods for providing substances to and from an array
ES2552937T3 (es) 2008-06-06 2015-12-03 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Factor de predicción de supervivencia para linfoma difuso de células B grandes
US20100087325A1 (en) * 2008-10-07 2010-04-08 Illumina, Inc. Biological sample temperature control system and method
WO2010048337A2 (en) 2008-10-22 2010-04-29 Illumina, Inc. Preservation of information related to genomic dna methylation
US20110212083A1 (en) 2008-11-06 2011-09-01 University Of Miami Office Of Technology Transfer Role of soluble upar in the pathogenesis of proteinuric kidney disease
ES2595410T3 (es) 2009-01-07 2016-12-29 Myriad Genetics, Inc. Biomarcadores de cáncer
US20100267092A1 (en) * 2009-02-09 2010-10-21 Frederic Zenhausern Components
US20100204057A1 (en) * 2009-02-10 2010-08-12 Samsung Electronics Co., Ltd. Substrate for microarray, method of manufacturing microarray using the same and method of obtaining light data from microarray
IL313131A (en) 2009-02-11 2024-07-01 Caris Mpi Inc Molecular characterization of tumors
US9767342B2 (en) 2009-05-22 2017-09-19 Affymetrix, Inc. Methods and devices for reading microarrays
CN102858995B (zh) 2009-09-10 2016-10-26 森特瑞隆技术控股公司 靶向测序方法
US10174368B2 (en) 2009-09-10 2019-01-08 Centrillion Technology Holdings Corporation Methods and systems for sequencing long nucleic acids
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
CA2779223A1 (en) 2009-10-27 2011-05-12 Caris Mpi, Inc. Molecular profiling for personalized medicine
US20110201008A1 (en) * 2009-12-01 2011-08-18 University Of Miami Assays, methods and kits for measuring response to therapy and predicting clinical outcome in patients with b-cell lymphoma
US8501122B2 (en) 2009-12-08 2013-08-06 Affymetrix, Inc. Manufacturing and processing polymer arrays
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
US9798855B2 (en) 2010-01-07 2017-10-24 Affymetrix, Inc. Differential filtering of genetic data
WO2011091435A2 (en) 2010-01-25 2011-07-28 Mount Sinai School Of Medicine Methods of treating liver disease
PL2531880T3 (pl) 2010-02-01 2017-09-29 Illumina Inc. Sposoby ogniskowania oraz układy optyczne i zespoły optyczne realizujące te sposoby
CN202281746U (zh) 2010-03-06 2012-06-20 伊鲁米那股份有限公司 检测来自样品光信号的测定设备及其光学组件和光学系统
CA2797093C (en) 2010-04-26 2019-10-29 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase
CA2797362C (en) 2010-04-27 2020-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases
WO2011139853A2 (en) 2010-04-28 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
EP2563383B1 (de) 2010-04-29 2017-03-01 Atyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von valyl-trna-synthetasen
US8986680B2 (en) 2010-04-29 2015-03-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases
CA2797977C (en) 2010-05-03 2019-08-20 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases
WO2011139986A2 (en) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases
CN103140233B (zh) 2010-05-03 2017-04-05 Atyr 医药公司 与甲硫氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
EP2566499B1 (de) 2010-05-04 2017-01-25 aTyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten aus einem p38-multi-trna-synthetase-komplex
CA2799197C (en) 2010-05-14 2019-10-29 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
AU2011258106B2 (en) 2010-05-27 2017-02-23 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases
CN103118694B (zh) 2010-06-01 2016-08-03 Atyr医药公司 与赖氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
WO2011159942A1 (en) 2010-06-18 2011-12-22 Illumina, Inc. Conformational probes and methods for sequencing nucleic acids
EP3812469A1 (de) 2010-07-07 2021-04-28 Myriad Genetics, Inc. Gensignaturen für krebsprognosen
JP6116479B2 (ja) 2010-07-12 2017-04-19 エータイアー ファーマ， インコーポレイテッド グリシルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
US20130040375A1 (en) 2011-08-08 2013-02-14 Tandem Diagnotics, Inc. Assay systems for genetic analysis
US8700338B2 (en) 2011-01-25 2014-04-15 Ariosa Diagnosis, Inc. Risk calculation for evaluation of fetal aneuploidy
US10167508B2 (en) 2010-08-06 2019-01-01 Ariosa Diagnostics, Inc. Detection of genetic abnormalities
US10533223B2 (en) 2010-08-06 2020-01-14 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US11203786B2 (en) 2010-08-06 2021-12-21 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US20140342940A1 (en) 2011-01-25 2014-11-20 Ariosa Diagnostics, Inc. Detection of Target Nucleic Acids using Hybridization
US20130261003A1 (en) 2010-08-06 2013-10-03 Ariosa Diagnostics, In. Ligation-based detection of genetic variants
US11031095B2 (en) 2010-08-06 2021-06-08 Ariosa Diagnostics, Inc. Assay systems for determination of fetal copy number variation
US20120034603A1 (en) 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
JP5964304B2 (ja) 2010-08-25 2016-08-03 エータイアー ファーマ， インコーポレイテッド チロシルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
WO2012050920A1 (en) 2010-09-29 2012-04-19 Illumina, Inc. Compositions and methods for sequencing nucleic acids
US8753816B2 (en) 2010-10-26 2014-06-17 Illumina, Inc. Sequencing methods
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
US9994897B2 (en) 2013-03-08 2018-06-12 Ariosa Diagnostics, Inc. Non-invasive fetal sex determination
US8756020B2 (en) 2011-01-25 2014-06-17 Ariosa Diagnostics, Inc. Enhanced risk probabilities using biomolecule estimations
US20120190021A1 (en) 2011-01-25 2012-07-26 Aria Diagnostics, Inc. Detection of genetic abnormalities
US11270781B2 (en) 2011-01-25 2022-03-08 Ariosa Diagnostics, Inc. Statistical analysis for non-invasive sex chromosome aneuploidy determination
US10131947B2 (en) 2011-01-25 2018-11-20 Ariosa Diagnostics, Inc. Noninvasive detection of fetal aneuploidy in egg donor pregnancies
EP2813851B1 (de) 2011-02-24 2016-06-08 Hill's Pet Nutrition, Inc. Zusammensetzungen und Verfahren zur Diagnostizierung von Nierenerkrankungen bei Katzen
WO2012118745A1 (en) 2011-02-28 2012-09-07 Arnold Oliphant Assay systems for detection of aneuploidy and sex determination
US20120252682A1 (en) 2011-04-01 2012-10-04 Maples Corporate Services Limited Methods and systems for sequencing nucleic acids
US8778848B2 (en) 2011-06-09 2014-07-15 Illumina, Inc. Patterned flow-cells useful for nucleic acid analysis
WO2012174294A1 (en) 2011-06-15 2012-12-20 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing and monitoring hyperthyroidism in a feline
US8712697B2 (en) 2011-09-07 2014-04-29 Ariosa Diagnostics, Inc. Determination of copy number variations using binomial probability calculations
EP2769198B1 (de) 2011-10-18 2016-05-25 Luminex Corporation Verfahren und systeme für die bilddatenverarbeitung
CA2856163C (en) 2011-10-28 2019-05-07 Illumina, Inc. Microarray fabrication system and method
AU2012355775B2 (en) 2011-12-19 2015-10-08 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing and treating hyperthyroidism in companion animals
EP2807271B1 (de) 2012-01-24 2018-08-22 CD Diagnostics, Inc. System zum nachweis einer infektion in der synovialflüssigkeit
EP2807272A1 (de) 2012-01-27 2014-12-03 Ventana Medical Systems, Inc. Vorrichtungen und verfahren zur erkennung von bioanalyten mit optisch enträtselbaren mustern
EP2814514B1 (de) 2012-02-16 2017-09-13 Atyr Pharma, Inc. Histidyl-trna-synthetasen zur behandlung von autoimmun- und entzündungserkrankungen
US10202628B2 (en) 2012-02-17 2019-02-12 President And Fellows Of Harvard College Assembly of nucleic acid sequences in emulsions
EP3321378B1 (de) 2012-02-27 2021-11-10 Becton, Dickinson and Company Zusammensetzungen für molekularen zählung
WO2013130512A2 (en) 2012-02-27 2013-09-06 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags
US10289800B2 (en) 2012-05-21 2019-05-14 Ariosa Diagnostics, Inc. Processes for calculating phased fetal genomic sequences
WO2013184905A1 (en) 2012-06-06 2013-12-12 Myriad Genetics, Inc. Hereditary cancer genes
US8892523B2 (en) 2012-06-08 2014-11-18 Commvault Systems, Inc. Auto summarization of content
CN104583421A (zh) 2012-07-19 2015-04-29 阿瑞奥萨诊断公司 遗传变体的基于多重的顺序连接的检测
EP2885626B1 (de) 2012-08-20 2020-03-04 Illumina, Inc. Ein integriertes detektions-, durchflusszell- und photonik-gerät (dfp)
ES2938766T3 (es) 2012-11-16 2023-04-14 Myriad Genetics Inc Firmas génicas para el pronóstico de cáncer
CN104937111B (zh) 2012-11-27 2018-05-11 智利天主教教皇大学 用于诊断甲状腺肿瘤的组合物和方法
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US11021752B2 (en) 2013-03-15 2021-06-01 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
WO2014144495A1 (en) 2013-03-15 2014-09-18 Abvitro, Inc. Single cell bar-coding for antibody discovery
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
EP3633048B1 (de) 2013-03-27 2022-10-12 Alan Handyside Beurteilung des risikos auf aneuploidie
US9134931B2 (en) 2013-04-30 2015-09-15 Hewlett-Packard Development Company, L.P. Printing content over a network
CN105074011B (zh) 2013-06-13 2020-10-02 阿瑞奥萨诊断公司 用于非入侵性性染色体非整倍性确定的统计分析
CN105705659B (zh) 2013-08-28 2019-11-29 贝克顿迪金森公司 大规模平行单细胞分析
US9352315B2 (en) 2013-09-27 2016-05-31 Taiwan Semiconductor Manufacturing Company, Ltd. Method to produce chemical pattern in micro-fluidic structure
ES2738289T3 (es) 2013-11-06 2020-01-21 Hospital Clinic Barcelona Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión
JP6666852B2 (ja) 2014-01-16 2020-03-18 イルミナ インコーポレイテッド 前立腺がん再発の予後に関する遺伝子発現パネル
CN106460071B (zh) 2014-04-22 2021-09-10 一龙公司 增强和/或预测dna扩增的组合物和方法
CA2947624A1 (en) 2014-05-13 2015-11-19 Myriad Genetics, Inc. Gene signatures for cancer prognosis
EP3164508B1 (de) 2014-07-02 2023-06-07 Myriad myPath, LLC Gene und gensignaturen zur diagnose und behandlung von melanomen
US10590483B2 (en) 2014-09-15 2020-03-17 Abvitro Llc High-throughput nucleotide library sequencing
BR112017008082A2 (pt) 2014-10-20 2017-12-26 Envirologix Inc composições e métodos para detectar um vírus de rna
CA2975328A1 (en) 2015-01-30 2016-08-04 Envirologix Inc. Substrates for a nicking and extension reaction
WO2016130572A2 (en) 2015-02-10 2016-08-18 Dana-Farber Cancer Institute, Inc. Methods of determining levels of exposure to radiation and uses thereof
CA2979850C (en) 2015-03-24 2020-07-21 Illumina, Inc. Methods, carrier assemblies, and systems for imaging samples for biological or chemical analysis
KR102134953B1 (ko) 2015-05-29 2020-07-16 일루미나, 인코포레이티드 지정된 반응을 수행하기 위한 샘플 캐리어 및 검정 시스템
EP3331572A4 (de) 2015-08-04 2019-05-01 CD Diagnostics, Inc. Verfahren zur erkennung von unerwünschter lokaler gewebereaktionsnekrose
CN106434873B (zh) 2015-08-13 2021-08-27 生捷科技控股公司 使核酸分子同步化的方法
CN116338219A (zh) 2015-08-24 2023-06-27 亿明达股份有限公司 用于生物和化学测定的线路内蓄压器和流量控制系统
KR20180085717A (ko) 2015-09-24 2018-07-27 에이비비트로, 엘엘씨 친화성-올리고뉴클레오타이드 콘쥬게이트 및 그것의 사용
AU2016326734B2 (en) 2015-09-25 2022-07-07 Abvitro Llc High throughput process for T cell receptor target identification of natively-paired T cell receptor sequences
CN108138226B (zh) 2015-10-18 2022-02-11 阿费梅特里克斯公司 单核苷酸多态性和插入缺失的多等位基因基因分型
WO2017087819A1 (en) 2015-11-19 2017-05-26 Myriad Genetics, Inc. Signatures for predicting cancer immune therapy response
CA3010240A1 (en) 2016-01-06 2017-07-13 Alexander Gutin Genes and gene signatures for diagnosis and treatment of melanoma
ES2859423T3 (es) 2016-04-20 2021-10-04 Us Health Evaluación del linfoma de células del manto y procedimientos relacionados con el mismo
WO2017193062A1 (en) 2016-05-06 2017-11-09 Myriad Genetics, Inc. Gene signatures for renal cancer prognosis
WO2017218777A1 (en) 2016-06-17 2017-12-21 California Institute Of Technology Nucleic acid reactions and related methods and compositions
AU2017332495A1 (en) 2016-09-24 2019-04-11 Abvitro Llc Affinity-oligonucleotide conjugates and uses thereof
WO2018064116A1 (en) 2016-09-28 2018-04-05 Illumina, Inc. Methods and systems for data compression
US10540516B2 (en) 2016-10-13 2020-01-21 Commvault Systems, Inc. Data protection within an unsecured storage environment
US10922189B2 (en) 2016-11-02 2021-02-16 Commvault Systems, Inc. Historical network data-based scanning thread generation
US10389810B2 (en) 2016-11-02 2019-08-20 Commvault Systems, Inc. Multi-threaded scanning of distributed file systems
US20210003570A1 (en) 2017-05-10 2021-01-07 Rowan University Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis
WO2018213803A1 (en) 2017-05-19 2018-11-22 Neon Therapeutics, Inc. Immunogenic neoantigen identification
US12637716B1 (en) 2017-06-02 2026-05-26 Myriad Genetics, Inc. Detecting cancer risk
US12577622B2 (en) 2017-06-02 2026-03-17 Myriad Genetics, Inc. Detecting cancer risk
EP3638814B8 (de) 2017-06-14 2023-06-21 The United States of America, as Represented by The Secretary, Department of Health and Human Services Verfahren zur bestimmung des lymphomtyps
WO2019005763A1 (en) 2017-06-26 2019-01-03 Phase Genomics Inc. METHOD FOR REGROUPING DNA SEQUENCES
WO2019092269A1 (en) 2017-11-13 2019-05-16 F. Hoffmann-La Roche Ag Devices for sample analysis using epitachophoresis
US10642886B2 (en) 2018-02-14 2020-05-05 Commvault Systems, Inc. Targeted search of backup data using facial recognition
US20190251204A1 (en) 2018-02-14 2019-08-15 Commvault Systems, Inc. Targeted search of backup data using calendar event data
EP4600742A3 (de) 2018-05-29 2026-03-11 Centrillion Technologies, Inc. Erhöhung der effizienz photochemischer reaktionen auf substraten
US20210269862A1 (en) 2018-06-18 2021-09-02 Igenomix, S.L. Methods for assessing endometrial transformation
NL2021377B1 (en) 2018-07-03 2020-01-08 Illumina Inc Interposer with first and second adhesive layers
EP3864165A4 (de) 2018-10-09 2022-08-03 Genecentric Therapeutics, Inc. Nachweis von ursprungskrebszellen
EP3864403A1 (de) 2018-10-12 2021-08-18 F. Hoffmann-La Roche AG Nachweisverfahren für die automation eines epitachophoreseablaufs
KR20210111254A (ko) 2018-11-30 2021-09-10 캐리스 엠피아이, 아이엔씨. 차세대 분자 프로파일링
CN114051537A (zh) 2019-04-17 2022-02-15 艾基诺米公司 用于早期诊断子宫平滑肌瘤和平滑肌肉瘤的改进方法
JP7441243B2 (ja) 2019-05-14 2024-02-29 エフ． ホフマン－ラ ロシュ アーゲー 試料分析のための装置および方法
IL293489A (en) 2019-12-02 2022-08-01 Caris Mpi Inc predictor of pan-cancer platinum response
MX2022009999A (es) 2020-02-14 2023-01-19 Caris Mpi Inc Puntuacion de prevalencia genomica panomica.
US20230215515A1 (en) 2021-12-23 2023-07-06 Illumina Software, Inc. Facilitating secure execution of external workflows for genomic sequencing diagnostics
WO2023122363A1 (en) 2021-12-23 2023-06-29 Illumina Software, Inc. Dynamic graphical status summaries for nucelotide sequencing
AU2022425440A1 (en) 2021-12-29 2024-07-11 Illumina, Inc. Automatically switching variant analysis model versions for genomic analysis applications

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2886241A (en) * 1952-08-26 1959-05-12 Rca Corp Code converter
US3216313A (en) * 1961-06-23 1965-11-09 Bausch & Lomb Monochromator of the type having a plane grating therein
GB1077501A (en) * 1964-02-04 1967-08-02 Nat Res Dev Scanning spectrophotometer
US3802966A (en) * 1969-08-22 1974-04-09 Ethyl Corp Apparatus for delivering a fluid suspension to a forming unit clear reactor power plant
US3632212A (en) * 1970-06-01 1972-01-04 Honeywell Inc Gas temperature measurement system employing a laser
AT353497B (de) * 1972-05-23 1979-11-12 Leitz Ernst Gmbh Vorrichtung an mikroskopen, zum automatischen fokussieren des geraetes auf unterschiedliche objekt-ebenen
US3984171A (en) * 1974-08-21 1976-10-05 Image Information Inc. Linear scan system
JPS6112373B2 (de) * 1974-09-04 1986-04-08 Hitachi Ltd
US4070111A (en) * 1976-06-10 1978-01-24 Nicolas James Harrick Rapid scan spectrophotometer
US4180739A (en) * 1977-12-23 1979-12-25 Varian Associates, Inc. Thermostatable flow cell for fluorescence measurements
US4448534A (en) * 1978-03-30 1984-05-15 American Hospital Corporation Antibiotic susceptibility testing
US4204929A (en) * 1978-04-18 1980-05-27 University Patents, Inc. Isoelectric focusing method
US4176925A (en) * 1978-06-07 1979-12-04 Gte Laboratories Incorporated Laser scanner for photolithography of slotted mask color cathode ray tubes
US4342905A (en) * 1979-08-31 1982-08-03 Nippon Kogaku K.K. Automatic focusing device of a microscope
JPS5817767A (ja) * 1981-07-23 1983-02-02 Fuji Photo Film Co Ltd 画像走査装置
US4708494A (en) * 1982-08-06 1987-11-24 Marcos Kleinerman Methods and devices for the optical measurement of temperature with luminescent materials
DE3245939C2 (de) * 1982-12-11 1985-12-19 Fa. Carl Zeiss, 7920 Heidenheim Vorrichtung zur Erzeugung eines Bildes des Augenhintergrundes
US4537861A (en) * 1983-02-03 1985-08-27 Elings Virgil B Apparatus and method for homogeneous immunoassay
US4626684A (en) * 1983-07-13 1986-12-02 Landa Isaac J Rapid and automatic fluorescence immunoassay analyzer for multiple micro-samples
US4580895A (en) * 1983-10-28 1986-04-08 Dynatech Laboratories, Incorporated Sample-scanning photometer
GB8429212D0 (en) * 1984-11-19 1984-12-27 Vincent Patents Ltd Exhaust systems for ic engines
JPS61290311A (ja) * 1985-06-19 1986-12-20 Hitachi Ltd はんだ付部の検査装置及びその方法
DD254998A1 (de) * 1985-07-26 1988-03-16 Zeiss Jena Veb Carl Anordnung zur bildlichen darstellung und analyse von fluoreszenzsignalen
US5164598A (en) * 1985-08-05 1992-11-17 Biotrack Capillary flow device
US4963498A (en) * 1985-08-05 1990-10-16 Biotrack Capillary flow device
EP0254644A3 (de) * 1986-07-22 1990-07-18 Schlumberger Technologies, Inc. Maskenausrichtung und Messung von kritischen Dimensionen in integrierten Schaltungen
JPS63167313A (ja) * 1986-12-27 1988-07-11 Hitachi Ltd 自動焦点制御方法
JPH0750094B2 (ja) * 1987-01-28 1995-05-31 富士写真フイルム株式会社 化学分析スライドの連続製造方法
US4844617A (en) * 1988-01-20 1989-07-04 Tencor Instruments Confocal measuring microscope with automatic focusing
US5001766A (en) * 1988-05-16 1991-03-19 At&T Bell Laboratories Apparatus and method for skew control of document images
US5382511A (en) * 1988-08-02 1995-01-17 Gene Tec Corporation Method for studying nucleic acids within immobilized specimens
US5188963A (en) * 1989-11-17 1993-02-23 Gene Tec Corporation Device for processing biological specimens for analysis of nucleic acids
US5281516A (en) * 1988-08-02 1994-01-25 Gene Tec Corporation Temperature control apparatus and method
US5320808A (en) * 1988-08-02 1994-06-14 Abbott Laboratories Reaction cartridge and carousel for biological sample analyzer
US5720928A (en) * 1988-09-15 1998-02-24 New York University Image processing and analysis of individual nucleic acid molecules
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5527681A (en) * 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5061075A (en) * 1989-08-07 1991-10-29 Alfano Robert R Optical method and apparatus for diagnosing human spermatozoa
US5346672A (en) * 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
US5091652A (en) * 1990-01-12 1992-02-25 The Regents Of The University Of California Laser excited confocal microscope fluorescence scanner and method
US5132524A (en) * 1990-05-21 1992-07-21 Lazerdata Corporation Multi directional laser scanner
JP3001612B2 (ja) * 1990-06-22 2000-01-24 ファナック株式会社 スキャナ用ガルバノメータの作動制御装置
GB9014263D0 (en) * 1990-06-27 1990-08-15 Dixon Arthur E Apparatus and method for spatially- and spectrally- resolvedmeasurements
GB9015793D0 (en) * 1990-07-18 1990-09-05 Medical Res Council Confocal scanning optical microscope
US5124102A (en) * 1990-12-11 1992-06-23 E. I. Du Pont De Nemours And Company Fabric useful as a concrete form liner
US5817462A (en) * 1995-02-21 1998-10-06 Applied Spectral Imaging Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding
US5198871A (en) * 1991-06-18 1993-03-30 Southwest Research Institute Laser-induced-fluorescence inspection of jet fuels
DE69208413T2 (de) * 1991-08-22 1996-11-14 Kla Instr Corp Gerät zur automatischen Prüfung von Photomaske
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5384261A (en) * 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US5310469A (en) * 1991-12-31 1994-05-10 Abbott Laboratories Biosensor with a membrane containing biologically active material
GB9218482D0 (en) * 1992-09-01 1992-10-14 Dixon Arthur E Apparatus and method for scanning laser imaging of macroscopic samples
US5235180A (en) * 1992-03-05 1993-08-10 General Scanning, Inc. Rotary motor having an angular position transducer and galvanometer scanning system employing such motor
US5304487A (en) * 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
US5486335A (en) * 1992-05-01 1996-01-23 Trustees Of The University Of Pennsylvania Analysis based on flow restriction
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5487115A (en) * 1992-05-14 1996-01-23 United Parcel Service Method and apparatus for determining the fine angular orientation of bar code symbols in two-dimensional CCD images
JP2851023B2 (ja) * 1992-06-29 1999-01-27 株式会社鷹山 Ｉｃの傾き検査方法
US5471248A (en) * 1992-11-13 1995-11-28 National Semiconductor Corporation System for tile coding of moving images
US5497773A (en) * 1993-03-12 1996-03-12 Kabushiki Kaisha Toshiba Nuclear magnetic resonance imaging with patient protection against nerve stimulation and image quality protection against artifacts
US5604819A (en) * 1993-03-15 1997-02-18 Schlumberger Technologies Inc. Determining offset between images of an IC
US5424841A (en) * 1993-05-28 1995-06-13 Molecular Dynamics Apparatus for measuring spatial distribution of fluorescence on a substrate
DE69418248T2 (de) * 1993-06-03 1999-10-14 Hamamatsu Photonics Kk Optisches Laser-Abtastsystem mit Axikon
US5858659A (en) * 1995-11-29 1999-01-12 Affymetrix, Inc. Polymorphism detection
US5861242A (en) * 1993-06-25 1999-01-19 Affymetrix, Inc. Array of nucleic acid probes on biological chips for diagnosis of HIV and methods of using the same
US5381224A (en) * 1993-08-30 1995-01-10 A. E. Dixon Scanning laser imaging system
US5532873A (en) * 1993-09-08 1996-07-02 Dixon; Arthur E. Scanning beam laser microscope with wide range of magnification
US5494124A (en) * 1993-10-08 1996-02-27 Vortexx Group, Inc. Negative pressure vortex nozzle
US6045996A (en) * 1993-10-26 2000-04-04 Affymetrix, Inc. Hybridization assays on oligonucleotide arrays
US6090555A (en) 1997-12-11 2000-07-18 Affymetrix, Inc. Scanned image alignment systems and methods
US6741344B1 (en) * 1994-02-10 2004-05-25 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5631734A (en) * 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5578832A (en) * 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US5571639A (en) * 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US6287850B1 (en) * 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
DE69527585T2 (de) * 1994-06-08 2003-04-03 Affymetrix, Inc. Verfahren und Vorrichtung zum Verpacken von Chips
US5459325A (en) * 1994-07-19 1995-10-17 Molecular Dynamics, Inc. High-speed fluorescence scanner
DE69530072T2 (de) * 1994-12-08 2004-03-04 Molecular Dynamics, Sunnyvale System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung
US5886353A (en) * 1995-04-21 1999-03-23 Thermotrex Corporation Imaging device
US5916747A (en) * 1995-06-30 1999-06-29 Visible Genetics Inc. Method and apparatus for alignment of signals for use in DNA based-calling
US5585639A (en) * 1995-07-27 1996-12-17 Hewlett-Packard Company Optical scanning apparatus
US5733729A (en) * 1995-09-14 1998-03-31 Affymetrix, Inc. Computer-aided probability base calling for arrays of nucleic acid probes on chips
US5801970A (en) * 1995-12-06 1998-09-01 Martin Marietta Corporation Model-based feature tracking system
US5835620A (en) * 1995-12-19 1998-11-10 Neuromedical Systems, Inc. Boundary mapping system and method
US5646411A (en) * 1996-02-01 1997-07-08 Molecular Dynamics, Inc. Fluorescence imaging system compatible with macro and micro scanning objectives
WO1997029212A1 (en) * 1996-02-08 1997-08-14 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US5721435A (en) * 1996-04-09 1998-02-24 Hewlett Packard Company Methods and apparatus for measuring optical properties of biological and chemical substances
EP0902885A4 (de) * 1996-05-16 2006-09-27 Affymetrix Inc System und verfahren zur erkennung markierter materialien
US5917588A (en) * 1996-11-04 1999-06-29 Kla-Tencor Corporation Automated specimen inspection system for and method of distinguishing features or anomalies under either bright field or dark field illumination
WO1998029736A1 (en) * 1996-12-31 1998-07-09 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
US6100030A (en) * 1997-01-10 2000-08-08 Pioneer Hi-Bred International, Inc. Use of selective DNA fragment amplification products for hybridization-based genetic fingerprinting, marker assisted selection, and high-throughput screening
US20020042048A1 (en) * 1997-01-16 2002-04-11 Radoje Drmanac Methods and compositions for detection or quantification of nucleic acid species
US5812272A (en) * 1997-01-30 1998-09-22 Hewlett-Packard Company Apparatus and method with tiled light source array for integrated assay sensing
US6122042A (en) * 1997-02-07 2000-09-19 Wunderman; Irwin Devices and methods for optically identifying characteristics of material objects
US6349144B1 (en) * 1998-02-07 2002-02-19 Biodiscovery, Inc. Automated DNA array segmentation and analysis
US6486335B1 (en) * 1998-03-31 2002-11-26 Council Of Scientific & Industrial Research (Csir) Process for the preparation of refined hard sugarcane wax having improved qualities from press mud
US6242266B1 (en) * 1999-04-30 2001-06-05 Agilent Technologies Inc. Preparation of biopolymer arrays
US6362832B1 (en) * 1999-09-01 2002-03-26 Packard Bioscience Company Method and system for overlaying at least three microarray images to obtain a multicolor composite image
US6077674A (en) * 1999-10-27 2000-06-20 Agilent Technologies Inc. Method of producing oligonucleotide arrays with features of high purity
US6406849B1 (en) * 1999-10-29 2002-06-18 Agilent Technologies, Inc. Interrogating multi-featured arrays
US7027629B2 (en) * 1999-11-05 2006-04-11 Agilent Technologies, Inc. Method of extracting locations of nucleic acid array features
EP1967595A3 (de) * 2000-02-16 2008-12-03 Illumina, Inc. Paralleles Genotypisieren von mehreren Patientenproben
US6571005B1 (en) * 2000-04-21 2003-05-27 The Regents Of The University Of California Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data
US6591196B1 (en) * 2000-06-06 2003-07-08 Agilent Technologies Inc. Method and system for extracting data from surface array deposited features
US6599693B1 (en) * 2000-07-31 2003-07-29 Agilent Technologies Inc. Array fabrication
US6829376B2 (en) * 2000-10-24 2004-12-07 Affymetrix, Inc. Computer software system, method, and product for scanned image alignment
US20050049796A1 (en) * 2003-09-03 2005-03-03 Webb Peter G. Methods for encoding non-biological information on microarrays
US20050048506A1 (en) * 2003-09-03 2005-03-03 Fredrick Joseph P. Methods for encoding non-biological information on microarrays

Also Published As

Publication number Publication date
CA2255384A1 (en) 1999-06-11
EP0923050A3 (de) 2002-07-31
EP0923050A2 (de) 1999-06-16
DE69827913T2 (de) 2005-04-07
JP2000069998A (ja) 2000-03-07
US20060258002A1 (en) 2006-11-16
US20060165313A1 (en) 2006-07-27
DE69827913D1 (de) 2005-01-05
US6611767B1 (en) 2003-08-26
EP0923050B1 (de) 2004-12-01
US20040096883A1 (en) 2004-05-20
US20050037367A9 (en) 2005-02-17
US6090555A (en) 2000-07-18

Similar Documents

Publication Publication Date Title
DE69827913D1 (de) Systeme und Verfahren zur Ausrichtung eines abgetasteten Bildes
DE69533117D1 (de) Verfahren zur Bearbeitung von Überlagerungsbildern
DE69523853D1 (de) Verfahren und Vorrichtung zur Kontrollierung von hauptsachlich runden Gegenständen
DE69939415D1 (de) System und Verfahren zur Handhabung von Gebieten innerhalb eines abgetasteten Bildes
DE69029403D1 (de) Verfahren und vorrichtung zur autoadaptiven einblendung von farbvideobildern
DE69322316D1 (de) Verfahren und Vorrichtung zum Lesen von Bildern eines Bildabtasters
DE3484644D1 (de) Vorrichtung und verfahren zur reproduktion eines originalfarbbildes.
DE69110925D1 (de) Verfahren und Vorrichtung zur Bilderfassung.
DE69426213D1 (de) Vorrichtung und Verfahren zur Ausrichtung von Bildern eines Filmelements bezüglich eines Linsenrasterelements
DE69710377D1 (de) Verfahren zur Änderung eines digitalen Bildes
DE59008311D1 (de) Verfahren und Vorrichtung zur Reduktion des Kantenflackerns eines Fernsehbildes.
DE59403478D1 (de) Verfahren zur segmentation von digitalen farbbildern
DE59509895D1 (de) Vorrichtung zur Erzeugung eines Bildes
DE69129214D1 (de) Verfahren zur Wiederherstellung von Bildern
DE69531316D1 (de) Vorrichtung zur Erzeugung eines Bildes durch Kombination von Teilbildern
DE69011535D1 (de) Verfahren und anordnung zur isolierung von signalen in echtzeit.
DE69728649D1 (de) Verfahren zur ergänzung eines digitalen bildes mit bildelementen
DE59509828D1 (de) Vorrichtung zur Erzeugung eines Bildes
DE69706802D1 (de) System und Verfahren zur Feststellung von weissen und schwarzen Punkte eines Farbbildes
AU7223191A (en) Process for removing nox emissions from combustion effluents
DE69713977D1 (de) Verfahren und Gerät zur Retuschierung eines digitalen Farbbildes
DE59402500D1 (de) Verfahren zur Kühlung eines Bauteils
DE69422353D1 (de) Verfahren zur Herstellung eines frequenzmodulierten Halbtonrasters
DE69415469D1 (de) Verfahren zur Verkleinerung des Bildes eines Dokuments
DE3750807D1 (de) Verfahren und Anordnung zur Erzeugung von Videomosaikeffekten.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties