ATE286064T1 - Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten - Google Patents

Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten

Info

Publication number
ATE286064T1
ATE286064T1 AT00938427T AT00938427T ATE286064T1 AT E286064 T1 ATE286064 T1 AT E286064T1 AT 00938427 T AT00938427 T AT 00938427T AT 00938427 T AT00938427 T AT 00938427T AT E286064 T1 ATE286064 T1 AT E286064T1
Authority
AT
Austria
Prior art keywords
aromatic
phytostanols
phytosterols
treatment
vascular diseases
Prior art date
Application number
AT00938427T
Other languages
English (en)
Inventor
James P Kutney
Radka K Milanova
Yangbing Ding
Honming Chen
Original Assignee
Forbes Medi Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forbes Medi Tech Inc filed Critical Forbes Medi Tech Inc
Application granted granted Critical
Publication of ATE286064T1 publication Critical patent/ATE286064T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00938427T 1999-06-21 2000-06-20 Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten ATE286064T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33781099A 1999-06-21 1999-06-21
PCT/CA2000/000731 WO2000078789A1 (en) 1999-06-21 2000-06-20 Aromatic and heterocyclic derivatives of phytosterols and/or phytostanols for use in treating or preventing cardiovascular disease

Publications (1)

Publication Number Publication Date
ATE286064T1 true ATE286064T1 (de) 2005-01-15

Family

ID=23322129

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00938427T ATE286064T1 (de) 1999-06-21 2000-06-20 Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten

Country Status (12)

Country Link
EP (1) EP1189923B1 (de)
JP (1) JP2003502437A (de)
CN (1) CN1370179A (de)
AT (1) ATE286064T1 (de)
AU (1) AU5383800A (de)
BR (1) BR0011865A (de)
CA (1) CA2376733A1 (de)
DE (1) DE60017128T2 (de)
ES (1) ES2235893T3 (de)
HK (1) HK1049487A1 (de)
PT (1) PT1189923E (de)
WO (1) WO2000078789A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1391506B1 (de) 2001-05-22 2011-02-02 Takeda Pharmaceutical Company Limited Tier mit gen-hypoexpression
US7306819B2 (en) 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
BR0311689A (pt) 2002-06-12 2008-01-15 Coca Cola Co processo para a produção de uma dispersão substancialmente estável, produto, e, composição
AU2003266885A1 (en) * 2002-09-25 2004-04-19 Forbes Medi-Tech Inc. Derivatives comprising sterols and/or stanols and specific classes of anti-inflammatory agents and use thereof in treating or preventing cardiovascular disease
US20080182801A1 (en) 2003-12-22 2008-07-31 Btg International Limited Core 2 glcnac-t inhibitors
GB0513881D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors III
GB0329667D0 (en) 2003-12-22 2004-01-28 King S College London Core 2 GlcNAc-T inhibitor
GB0513883D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Diagnosis of Atherosclerosis
GB0513888D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
JP5657902B2 (ja) * 2010-03-17 2015-01-21 株式会社コスモステクニカルセンター ポリオキシアルキレンステロールエーテル誘導体及び／又はポリオキシアルキレンスタノールエーテル誘導体、及びそれを含有する外用剤組成物
CN103450310A (zh) * 2013-08-19 2013-12-18 南昌大学 豆甾醇衍生物及其在制备抗癌药物中的应用
CN104434927A (zh) * 2014-12-16 2015-03-25 吉林农业大学 丙二酸双环戊烷并多氢菲酯b在制备降血压药物中的应用
CN104402961B (zh) * 2014-12-16 2016-01-13 吉林农业大学 四氢糠酸环戊烷并多氢菲酯a及其提取方法和药物用途
CN104402960B (zh) * 2014-12-16 2016-01-13 吉林农业大学 糠酸环戊烷并多氢菲酯a及其提取方法和药物用途
CN104402962B (zh) * 2014-12-16 2016-01-13 吉林农业大学 硫辛酸环戊烷并多氢菲酯c及其提取方法和药物用途
CN104387434B (zh) * 2014-12-16 2016-01-13 吉林农业大学 四氢糠酸环戊烷并多氢菲酯b及其提取方法和药物用途
CN104478982B (zh) * 2014-12-16 2016-04-06 吉林农业大学 糠酸环戊烷并多氢菲酯b及其提取方法和药物用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2586438A (en) * 1949-06-29 1952-02-19 Du Pont Sterol esters of nicotinic acid
CA2028759A1 (en) * 1989-11-22 1991-05-23 Jean-Marie Cassal Steroids
JPH07330611A (ja) * 1994-06-02 1995-12-19 Yakult Honsha Co Ltd ホスホリパーゼａ２阻害剤及びコレステロール吸収阻害剤

Also Published As

Publication number Publication date
JP2003502437A (ja) 2003-01-21
ES2235893T3 (es) 2005-07-16
CN1370179A (zh) 2002-09-18
DE60017128T2 (de) 2006-01-26
BR0011865A (pt) 2006-06-06
AU5383800A (en) 2001-01-09
EP1189923A1 (de) 2002-03-27
WO2000078789A1 (en) 2000-12-28
DE60017128D1 (de) 2005-02-03
PT1189923E (pt) 2005-05-31
HK1049487A1 (zh) 2003-05-16
EP1189923B1 (de) 2004-12-29
CA2376733A1 (en) 2000-12-28

Similar Documents

Publication Publication Date Title
ATE286064T1 (de) Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten
ATE273992T1 (de) Konjugate von ascorbinsäure und phytosterolen oder phytostanolen und ihre verwendung zur behandlung von gefässkrankheiten
BRPI0314308B8 (pt) antagonistas de opióide, seus usos, e composição farmacêutica
DE59610509D1 (de) Neue 4-(oxyalkoxyphenyl)-3-oxy-piperidine zur behandlung von herz- und niereninsuffizienz
NO943877L (no) Hemming av proliferasjon av glatte muskelceller og restenose
ATE401076T1 (de) Chinolinderivate als glucokinase liganden
ATE430727T1 (de) Alpha-(n-sulfonamid)acetamidderivate als beta- amyloidinhibitoren
NO20075065L (no) Anvendelse av isoflavonforbindelser til a behandle hjertesykdom
DE60315674D1 (de) Neue imidazopyridine und ihre verwendung
RU2011138835A (ru) Применение производного рапамицина
ATE294577T1 (de) Verwendung von sulfamat derivaten zur behandlung von impulsiven störungen
ES2102154T3 (es) Inhibicion de trombina.
NO994901L (no) Behandling av sentralnerveforstyrrelser ved selektive östrogenreseptormodulatorer
WO1999046279A3 (en) INHIBITORS OF TYPE 5 AND TYPE 3 17β-HYDROXYSTEROID DEHYDROGENASE AND METHODS FOR THEIR USE
DE60305514D1 (de) Neue verwendung von benzothiazolderivaten
ATE180669T1 (de) Verwendung von pregnanderivaten zur behandlung von tumoren
BRPI0413682A (pt) compostos, composição farmacêutica e respectivos métodos de preparação, de tratamento de infecção microbiana e de extermìnio de microrganismo e usos
MXPA02011511A (es) USO DE (+)-alfa û(2,3-dimetoxifenil)etil-1-[2-(4-fluorofenil)etil] -4-piperidin metanol o sus fármacos en el tratamiento de síntomas demencia y psicosis inducida por dofamina.
NO994903L (no) Behandling eller profylakse av prostatakreft og benign prostatahyperplasi med selektive östrogenreseptormodulatorer
DE69822626D1 (de) Verwendung eines nitroxids oder seiner prodrugs zur prophylaktischen und therapeutischen behandlung von krebs
ATE297926T1 (de) Hexahydropyrazino(1'2':1,6)-pyrido(3,4-b)indole 1,4-dion-derivate zur behandlung von cardiovaskulären erkrankungen und erektionsstörungen
NO20045505L (no) Nye derivater av androstan og androsten med askorbinsyre og anvendelse derav ved behandling eller hindring av forskjellige tilstander, sykdommer og forstyrrelser
NO870423D0 (no) 5-substituert octahydroindolizin-analgetika-forbindelser og 7-keto-mellomprodukt.
TR200103704T2 (tr) Terapötik ajanlar
ATE323714T1 (de) Krystalline zusammensetzungen enthaltend phytosterole und phytostanole oder derivate davon

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1189923

Country of ref document: EP

REN Ceased due to non-payment of the annual fee