ATE286064T1 - Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten - Google Patents

Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten

Info

Publication number
ATE286064T1
ATE286064T1 AT00938427T AT00938427T ATE286064T1 AT E286064 T1 ATE286064 T1 AT E286064T1 AT 00938427 T AT00938427 T AT 00938427T AT 00938427 T AT00938427 T AT 00938427T AT E286064 T1 ATE286064 T1 AT E286064T1
Authority
AT
Austria
Prior art keywords
aromatic
phytostanols
phytosterols
treatment
vascular diseases
Prior art date
Application number
AT00938427T
Other languages
English (en)
Inventor
James P Kutney
Radka K Milanova
Yangbing Ding
Honming Chen
Original Assignee
Forbes Medi Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forbes Medi Tech Inc filed Critical Forbes Medi Tech Inc
Application granted granted Critical
Publication of ATE286064T1 publication Critical patent/ATE286064T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00938427T 1999-06-21 2000-06-20 Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten ATE286064T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33781099A 1999-06-21 1999-06-21
PCT/CA2000/000731 WO2000078789A1 (en) 1999-06-21 2000-06-20 Aromatic and heterocyclic derivatives of phytosterols and/or phytostanols for use in treating or preventing cardiovascular disease

Publications (1)

Publication Number Publication Date
ATE286064T1 true ATE286064T1 (de) 2005-01-15

Family

ID=23322129

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00938427T ATE286064T1 (de) 1999-06-21 2000-06-20 Aromatische und heterozyklische derivate von phytosterolen und/oder phytostanolen zur behandlung von gefässkrankheiten

Country Status (12)

Country Link
EP (1) EP1189923B1 (de)
JP (1) JP2003502437A (de)
CN (1) CN1370179A (de)
AT (1) ATE286064T1 (de)
AU (1) AU5383800A (de)
BR (1) BR0011865A (de)
CA (1) CA2376733A1 (de)
DE (1) DE60017128T2 (de)
ES (1) ES2235893T3 (de)
HK (1) HK1049487A1 (de)
PT (1) PT1189923E (de)
WO (1) WO2000078789A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60239099D1 (de) 2001-05-22 2011-03-17 Takeda Pharmaceutical Tier mit gen-hypoexpression
US7306819B2 (en) 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
EP1549159B1 (de) 2002-06-12 2008-11-12 The Coca-Cola Company Pflanzliches sterol enthaltende getränke
JP2006503840A (ja) * 2002-09-25 2006-02-02 フォーブス メディ−テック インコーポレーテッド ステロール及び／又はスタノール及び抗炎症剤の特定の種類を含有する新規構造体及び組成物、並びに、心血管疾患、その根底にある高脂血症を含む病気、及び原因又は症状の一部として炎症を有する他の障害の治療又は予防におけるそれらの使用
US20080182801A1 (en) 2003-12-22 2008-07-31 Btg International Limited Core 2 glcnac-t inhibitors
GB0513881D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors III
GB0329667D0 (en) 2003-12-22 2004-01-28 King S College London Core 2 GlcNAc-T inhibitor
GB0513888D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
GB0513883D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Diagnosis of Atherosclerosis
JP5657902B2 (ja) * 2010-03-17 2015-01-21 株式会社コスモステクニカルセンター ポリオキシアルキレンステロールエーテル誘導体及び／又はポリオキシアルキレンスタノールエーテル誘導体、及びそれを含有する外用剤組成物
CN103450310A (zh) * 2013-08-19 2013-12-18 南昌大学 豆甾醇衍生物及其在制备抗癌药物中的应用
CN104402961B (zh) * 2014-12-16 2016-01-13 吉林农业大学 四氢糠酸环戊烷并多氢菲酯a及其提取方法和药物用途
CN104387434B (zh) * 2014-12-16 2016-01-13 吉林农业大学 四氢糠酸环戊烷并多氢菲酯b及其提取方法和药物用途
CN104402960B (zh) * 2014-12-16 2016-01-13 吉林农业大学 糠酸环戊烷并多氢菲酯a及其提取方法和药物用途
CN104434927A (zh) * 2014-12-16 2015-03-25 吉林农业大学 丙二酸双环戊烷并多氢菲酯b在制备降血压药物中的应用
CN104478982B (zh) * 2014-12-16 2016-04-06 吉林农业大学 糠酸环戊烷并多氢菲酯b及其提取方法和药物用途
CN104402962B (zh) * 2014-12-16 2016-01-13 吉林农业大学 硫辛酸环戊烷并多氢菲酯c及其提取方法和药物用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2586438A (en) * 1949-06-29 1952-02-19 Du Pont Sterol esters of nicotinic acid
CA2028759A1 (en) * 1989-11-22 1991-05-23 Jean-Marie Cassal Steroids
JPH07330611A (ja) * 1994-06-02 1995-12-19 Yakult Honsha Co Ltd ホスホリパーゼａ２阻害剤及びコレステロール吸収阻害剤

Also Published As

Publication number Publication date
CN1370179A (zh) 2002-09-18
HK1049487A1 (zh) 2003-05-16
EP1189923A1 (de) 2002-03-27
AU5383800A (en) 2001-01-09
DE60017128D1 (de) 2005-02-03
JP2003502437A (ja) 2003-01-21
DE60017128T2 (de) 2006-01-26
CA2376733A1 (en) 2000-12-28
EP1189923B1 (de) 2004-12-29
BR0011865A (pt) 2006-06-06
WO2000078789A1 (en) 2000-12-28
PT1189923E (pt) 2005-05-31
ES2235893T3 (es) 2005-07-16

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