ATE287258T1 - Verfahren zur herstellung von liposomen - Google Patents

Verfahren zur herstellung von liposomen

Info

Publication number: ATE287258T1
Authority: AT; Austria
Prior art keywords: liposomes; compositions; producing liposomes; regent; pharmaceuticals
Prior art date: 1998-06-18

Application number

AT99928051T

Other languages

English (en)

Inventor

Gregory Gregoriadis

Brahim Zadi

Pramukh Nalaka Jayasekera

Original Assignee

Secr Defence

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-18

Filing date

1999-06-16

Publication date

2005-02-15

1999-06-16 Application filed by Secr Defence filed Critical Secr Defence

2005-02-15 Application granted granted Critical

2005-02-15 Publication of ATE287258T1 publication Critical patent/ATE287258T1/de

Links

239000002502 liposome Substances 0.000 title abstract 4
238000004519 manufacturing process Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 3
238000000034 method Methods 0.000 abstract 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000001035 drying Methods 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Manufacturing Of Micro-Capsules (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT99928051T 1998-06-18 1999-06-16 Verfahren zur herstellung von liposomen ATE287258T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9813100.6A GB9813100D0 (en)	1998-06-18	1998-06-18	Method of forming liposomes
PCT/GB1999/001911 WO1999065465A1 (en)	1998-06-18	1999-06-16	Method of forming liposomes

Publications (1)

Publication Number	Publication Date
ATE287258T1 true ATE287258T1 (de)	2005-02-15

Family

ID=10833946

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99928051T ATE287258T1 (de)	1998-06-18	1999-06-16	Verfahren zur herstellung von liposomen

Country Status (15)

Country	Link
US (1)	US9675554B1 (de)
EP (1)	EP1087754B1 (de)
JP (1)	JP4567882B2 (de)
KR (1)	KR100658956B1 (de)
CN (1)	CN1312707A (de)
AT (1)	ATE287258T1 (de)
AU (1)	AU749499B2 (de)
CA (1)	CA2335183A1 (de)
DE (1)	DE69923315T2 (de)
GB (2)	GB9813100D0 (de)
NO (1)	NO20006442L (de)
NZ (1)	NZ508960A (de)
RU (1)	RU2216315C2 (de)
WO (1)	WO1999065465A1 (de)
ZA (1)	ZA200007507B (de)

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WO2002038128A1 (fr) *	2000-11-10	2002-05-16	Japan Science And Technology Corporation	Procede de preparation d'une dispersion de microsome
AU2002236526B9 (en) *	2000-11-15	2008-05-01	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Sol-fusin: use of GP64-6His to catalyze membrane fusion
BRPI0105509B8 (pt)	2001-11-05	2021-05-25	Univ Minas Gerais	formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga
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EP1530465B2 (de)	2002-06-26	2015-12-16	MediGene AG	Herstellung einer kationisch liposomalen zubereitung, einen lipophilen wirkstoff enthaltend
PT2286795T (pt) *	2002-06-26	2017-01-27	Syncore Biotechnology Co Ltd	Processo de produção de uma preparação lipossomal catiónica que compreende um composto lipófilo
US20050175683A1 (en) *	2003-10-24	2005-08-11	Yuanpeng Zhang	Preparation of lipid particles
LT3173073T (lt)	2004-05-03	2025-01-10	Ipsen Biopharm Ltd.	Liposomos, skirtos vaistų pristatymui
EP1802277B1 (de) *	2004-10-18	2010-01-13	Polymun Scientific Immunbiologische Forschung GmbH	Liposomale zusammensetzung einen wirkstoff zur relaxierung glatter muskulatur enthaltend, die herstellung dieser zusammensetzung und deren therapeutische verwendung
EP1928418B1 (de)	2005-09-30	2011-12-21	Lipoxen Technologies Limited	Liposomale impfstoff-zusammensetzung aus einem polysaccharid-antigen und einem protein-adjuvans
RU2300369C1 (ru) *	2005-12-27	2007-06-10	Наталья Ивановна Ларионова	Способ получения полиэлектролитных микрочастиц, содержащих инкапсулируемое вещество, чувствительных к изменению состава окружающей среды
JP5502480B2 (ja)	2006-09-18	2014-05-28	コンピュゲンエルティーディー．	生物活性ペプチド及びその使用方法
WO2009007848A2 (en)	2007-07-12	2009-01-15	Compugen Ltd.	Bioactive peptides and method of using same
JP5362998B2 (ja) *	2008-01-10	2013-12-11	第一ファインケミカル株式会社	乾燥リポソーム製剤
US9445975B2 (en)	2008-10-03	2016-09-20	Access Business Group International, Llc	Composition and method for preparing stable unilamellar liposomal suspension
US9713591B2 (en) *	2008-10-07	2017-07-25	Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd.	Composition of matter comprising liposomes embedded in a polymeric matrix and methods of using same
EP2184054A1 (de)	2008-11-08	2010-05-12	Lipoxen Technologies Limited	SiRNA-Abgabe
KR101795524B1 (ko)	2009-06-04	2017-11-08	고쿠리츠칸센쇼켄쿠죠	마이코플라즈마 감염증용 백신
RU2409668C1 (ru) *	2009-09-02	2011-01-20	Александр Анатольевич Ярославов	Способ получения иммобилизованных бислойных везикул
KR20110068831A (ko)	2009-12-16	2011-06-22	재단법인 전라남도생물산업진흥재단	리포좀 조성물, 그 제조방법, 및 폐렴 백신으로서의 그 용도
FR2958851B1 (fr) *	2010-04-16	2012-06-29	Xeda International	Nouvelles formulations d'ingredient(s) actif(s) d'origine vegetale ou leurs analogues synthetiques ou d'extrait(s) d'origine vegetale les contenant, et de lecithine
PL2661253T3 (pl)	2011-01-04	2017-08-31	Archivel Farma, Sl	Preparat liposomowy odpowiedni do leczenia lub zapobiegania gruźlicy
SI2768484T1 (sl)	2011-10-21	2019-12-31	Jazz Pharmaceuticals Research Llc	Liofilizirani liposomi
DK2802345T3 (en)	2012-01-12	2018-04-30	Archivel Farma Sl	MTB-C-VACCINE AGAINST ALLERGIC REACTIONS
EA023079B1 (ru) *	2012-12-24	2016-04-29	Общество С Ограниченной Ответственностью "Технология Лекарств"	Способ получения липосомальной формы иринотекана (варианты)
JP6866060B2 (ja) *	2014-10-27	2021-04-28	花王株式会社	精製茶抽出物の製造方法
WO2016108634A2 (ko) *	2014-12-30	2016-07-07	(주)셀트리온	표피성장인자와 리포좀의 하이브리드형 다중층 나노구조체 및 그 제조방법
US20180153824A1 (en) *	2015-05-27	2018-06-07	Nuvox Pharma Llc	Treatment of acute complications of sickle cell disease
US10086089B2 (en)	2015-09-18	2018-10-02	DNARx	Systems and methods for nucleic acid expression in vivo
EP4647126A3 (de)	2015-10-16	2026-02-11	Ipsen Biopharm Ltd.	Stabilisierung von pharmazeutischen camptothecinzusammensetzungen
CN116392609A (zh)	2017-03-23	2023-07-07	Dnarx公司	用于体内核酸表达的系统和方法
GB201707700D0 (en)	2017-05-12	2017-06-28	Glaxosmithkline Biologicals Sa	Dried composition
RU2697802C1 (ru) *	2018-08-23	2019-08-20	Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран)	Способ получения магнитных липосом

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US4880635B1 (en) *	1984-08-08	1996-07-02	Liposome Company	Dehydrated liposomes
US4857319A (en) *	1985-01-11	1989-08-15	The Regents Of The University Of California	Method for preserving liposomes
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JP2780755B2 (ja) *	1987-05-22	1998-07-30	ザリポソームカンパニー，インコーポレイテッド	プロスタグランジン‐脂質製剤
DE68916439T2 (de) *	1988-10-05	1994-10-20	Vestar Inc	Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.
RU2014071C1 (ru) *	1991-03-26	1994-06-15	Научно-производственный центр медицинской биотехнологии	Способ получения липосом, содержащих водорастворимые низкомолекулярные соединения
US5958881A (en) *	1991-04-25	1999-09-28	Korman; Louis Y.	Composition containing VIP for injection and a method of enhancing visualization of tissues during medical procedures
WO1993020802A1 (en) *	1992-04-09	1993-10-28	Northwestern University	Acoustically reflective liposomes and methods to make and use the same
ATE164515T1 (de) *	1993-11-05	1998-04-15	Amgen Inc	Herstellung von liposomen und verfahren zur substanzverkapselung
EP0914094A4 (de) *	1996-03-28	2000-03-01	Univ Illinois	Materialen und verfahren zur herstellung verbesserter liposomaler mittel
JP3693209B2 (ja) *	1996-04-11	2005-09-07	三菱化学株式会社	閉鎖小胞の製造方法
CA2202103C (en) *	1996-04-11	2007-01-09	Toshiaki Tagawa	Method for preparing closed vesicles
RU2123328C1 (ru) *	1996-04-19	1998-12-20	Государственный научный центр вирусологии и биотехнологии "Вектор"	Липосомальное противовирусное лекарственное средство для перорального применения
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1998
- 1998-06-18 GB GBGB9813100.6A patent/GB9813100D0/en not_active Ceased
1999
- 1999-06-16 WO PCT/GB1999/001911 patent/WO1999065465A1/en not_active Ceased
- 1999-06-16 US US09/719,795 patent/US9675554B1/en not_active Expired - Fee Related
- 1999-06-16 GB GB0030767A patent/GB2354166B/en not_active Expired - Lifetime
- 1999-06-16 NZ NZ508960A patent/NZ508960A/xx unknown
- 1999-06-16 KR KR1020007014404A patent/KR100658956B1/ko not_active Expired - Lifetime
- 1999-06-16 DE DE69923315T patent/DE69923315T2/de not_active Expired - Lifetime
- 1999-06-16 AT AT99928051T patent/ATE287258T1/de not_active IP Right Cessation
- 1999-06-16 CA CA002335183A patent/CA2335183A1/en not_active Abandoned
- 1999-06-16 RU RU2001101910/14A patent/RU2216315C2/ru active
- 1999-06-16 EP EP99928051A patent/EP1087754B1/de not_active Expired - Lifetime
- 1999-06-16 CN CN99809563A patent/CN1312707A/zh active Pending
- 1999-06-16 JP JP2000554345A patent/JP4567882B2/ja not_active Expired - Lifetime
- 1999-06-16 AU AU45180/99A patent/AU749499B2/en not_active Expired
2000
- 2000-12-14 ZA ZA200007505A patent/ZA200007507B/en unknown
- 2000-12-15 NO NO20006442A patent/NO20006442L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR100658956B1 (ko)	2006-12-21
GB2354166A (en)	2001-03-21
CA2335183A1 (en)	1999-12-23
NO20006442D0 (no)	2000-12-15
DE69923315T2 (de)	2006-04-06
GB0030767D0 (en)	2001-01-31
ZA200007507B (en)	2002-03-14
WO1999065465A1 (en)	1999-12-23
EP1087754B1 (de)	2005-01-19
AU4518099A (en)	2000-01-05
EP1087754A1 (de)	2001-04-04
GB2354166B (en)	2003-09-10
CN1312707A (zh)	2001-09-12
US9675554B1 (en)	2017-06-13
DE69923315D1 (de)	2005-02-24
NO20006442L (no)	2001-02-15
JP4567882B2 (ja)	2010-10-20
GB9813100D0 (en)	1998-08-19
KR20010053006A (ko)	2001-06-25
AU749499B2 (en)	2002-06-27
NZ508960A (en)	2002-11-26
RU2216315C2 (ru)	2003-11-20
JP2003513003A (ja)	2003-04-08

Legal Events

Date	Code	Title	Description
2005-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE287258T1 (de)	2005-02-15	Verfahren zur herstellung von liposomen
CA2158207A1 (en)	1996-03-14	Continuous Chewing Gum Manufacturing Process Using Rework Gum
ATE173397T1 (de)	1998-12-15	Liposomale antisense methylphosphonat oligo- nukleotide und verfahren zu deren herstellung sowie deren verwendung
DE59408535D1 (de)	1999-09-02	Dekorierte Keramik- und Glaserzeugnisse, Verfahren zu deren Herstellung und keramische Farbzusammensetzungen zur Durchführung des Verfahrens
DE69130647D1 (de)	1999-01-28	Verfahren zur herstellung von oligonukleotiden mit regellosen codonen
DE3689195D1 (de)	1993-11-25	Verfahren zur Herstellung von Aloe-Erzeugnissen, Erzeugnisse und Zusammensetzungen dazu.
ATE232210T1 (de)	2003-02-15	Verfahren zur herstellung von erythromicin a-oxim
DE69530242D1 (de)	2003-05-15	Verfahren zur Herstellung von Glutaminsäure durch Fermentation
DE69104280D1 (de)	1994-11-03	Verfahren zur Herstellung von hochreiner Isophthalsäure.
CA2284544A1 (en)	1998-10-15	Method for modifying papermaking sludge and products made therefrom
DE69115715D1 (de)	1996-02-01	Gemischte, phosphor und schwefel enthaltende reaktionsprodukte, hergestellt unter niedrigem druck, verwendbar in kraftübertragungszusammensetzungen und verfahren zu deren herstellung
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DE3763074D1 (de)	1990-07-12	Diperoxysaeure-vorlaeufer, verfahren zu deren herstellung und deren verwendung in bleichmittelzusammensetzungen.
EP1004638A3 (de)	2000-10-18	Wässriges Anstrichmittel, Verfahren zu seiner Herstellung und Kit zur Verwendung in diesem Verfahren
DE69808086D1 (de)	2002-10-24	Ein verfahren zur herstellung von 1,4,7,10-tetraazacyclododecan-1,4,7-triessigsäure und deren derivaten
DE69525332D1 (de)	2002-03-21	Verfahren zur Herstellung von Harnstoff in zwei separaten Reaktionszonen
DE69308531D1 (de)	1997-04-10	Cycloisomaltooligosaccharide; Enzym und Verfahren zu ihrer Herstellung, und Verfahren zur Herstellung von dem Enzym
ATE299858T1 (de)	2005-08-15	Verfahren zur herstellung von diaminodiphenylmethan und seiner höheren homologen
IT8919477A0 (it)	1989-02-17	Processo per la preparazione di 1,4 diidropiridine polisostituite in forma enantiomericamente pura.
ATE205498T1 (de)	2001-09-15	Verfahren zur herstellung von kaliumclavulanat
DE69105615D1 (de)	1995-01-19	Verfahren zur Herstellung von hochreiner Isophthalsäure.
ATE222705T1 (de)	2002-09-15	Stickstoff enthaltende zusammensetzung erhalten durch die hydrolyse von weizengluten und verfahren zu ihrer herstellung
FI971031A7 (fi)	1997-03-12	Purukumin jatkuvatoiminen valmistus kumipohjakonsentraatista
DE59803194D1 (de)	2002-04-04	Verfahren zur herstellung von 1,3-disubstituierten 2-nitroguanidinen
DE3762636D1 (de)	1990-06-13	Verfahren zur herstellung von alkalilauge ohne sulfidinhalt.