ATE287258T1 - Verfahren zur herstellung von liposomen - Google Patents

Verfahren zur herstellung von liposomen

Info

Publication number: ATE287258T1
Authority: AT; Austria
Prior art keywords: liposomes; compositions; producing liposomes; regent; pharmaceuticals
Prior art date: 1998-06-18

Application number

AT99928051T

Other languages

English (en)

Inventor

Gregory Gregoriadis

Brahim Zadi

Pramukh Nalaka Jayasekera

Original Assignee

Secr Defence

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-18

Filing date

1999-06-16

Publication date

2005-02-15

1999-06-16 Application filed by Secr Defence filed Critical Secr Defence

2005-02-15 Application granted granted Critical

2005-02-15 Publication of ATE287258T1 publication Critical patent/ATE287258T1/de

Links

239000002502 liposome Substances 0.000 title abstract 4
238000004519 manufacturing process Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 3
238000000034 method Methods 0.000 abstract 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000001035 drying Methods 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Manufacturing Of Micro-Capsules (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT99928051T 1998-06-18 1999-06-16 Verfahren zur herstellung von liposomen ATE287258T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9813100.6A GB9813100D0 (en)	1998-06-18	1998-06-18	Method of forming liposomes
PCT/GB1999/001911 WO1999065465A1 (en)	1998-06-18	1999-06-16	Method of forming liposomes

Publications (1)

Publication Number	Publication Date
ATE287258T1 true ATE287258T1 (de)	2005-02-15

Family

ID=10833946

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99928051T ATE287258T1 (de)	1998-06-18	1999-06-16	Verfahren zur herstellung von liposomen

Country Status (15)

Country	Link
US (1)	US9675554B1 (de)
EP (1)	EP1087754B1 (de)
JP (1)	JP4567882B2 (de)
KR (1)	KR100658956B1 (de)
CN (1)	CN1312707A (de)
AT (1)	ATE287258T1 (de)
AU (1)	AU749499B2 (de)
CA (1)	CA2335183A1 (de)
DE (1)	DE69923315T2 (de)
GB (2)	GB9813100D0 (de)
NO (1)	NO20006442L (de)
NZ (1)	NZ508960A (de)
RU (1)	RU2216315C2 (de)
WO (1)	WO1999065465A1 (de)
ZA (1)	ZA200007507B (de)

Families Citing this family (35)

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WO2002038128A1 (fr) *	2000-11-10	2002-05-16	Japan Science And Technology Corporation	Procede de preparation d'une dispersion de microsome
AU2002236526B9 (en) *	2000-11-15	2008-05-01	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Sol-fusin: use of GP64-6His to catalyze membrane fusion
BRPI0105509B8 (pt)	2001-11-05	2021-05-25	Univ Minas Gerais	formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga
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ATE444062T1 (de)	2002-06-26	2009-10-15	Medigene Ag	Herstellung einer kationisch liposomalen zubereitung, einen lipophilen wirkstoff enthaltend
SI2108362T1 (sl) *	2002-06-26	2013-08-30	Medigene Ag	Kationski nosilni sistem, ki vsebuje taksan
EP1677765A1 (de) *	2003-10-24	2006-07-12	Alza Corporation	Herstellung von lipidteilchen
UA86063C2 (ru)	2004-05-03	2009-03-25	Хермес Біосайенсез, Інк.	Липосомы для снабжения лекарств
CA2583332C (en) *	2004-10-18	2013-10-01	Polymun Scientific Immunbiologische Forschung Gmbh	Liposomal composition comprising an active ingredient for relaxing smooth muscle production and therapeutically use of said composition
EP1928418B1 (de)	2005-09-30	2011-12-21	Lipoxen Technologies Limited	Liposomale impfstoff-zusammensetzung aus einem polysaccharid-antigen und einem protein-adjuvans
RU2300369C1 (ru) *	2005-12-27	2007-06-10	Наталья Ивановна Ларионова	Способ получения полиэлектролитных микрочастиц, содержащих инкапсулируемое вещество, чувствительных к изменению состава окружающей среды
AU2007357448B2 (en)	2006-09-18	2012-09-06	Compugen Ltd	Bioactive peptides and method of using same
EP2167534B1 (de)	2007-07-12	2012-07-04	Compugen Ltd.	Bioaktive peptide und verfahren zu ihrer verwendung
JP5362998B2 (ja) *	2008-01-10	2013-12-11	第一ファインケミカル株式会社	乾燥リポソーム製剤
US9445975B2 (en)	2008-10-03	2016-09-20	Access Business Group International, Llc	Composition and method for preparing stable unilamellar liposomal suspension
CN102223878A (zh)	2008-10-07	2011-10-19	耶路撒冷希伯来大学伊森姆研究发展公司	包含鞘磷脂的脂质体系统
EP2184054A1 (de)	2008-11-08	2010-05-12	Lipoxen Technologies Limited	SiRNA-Abgabe
EP2438926B1 (de) *	2009-06-04	2016-03-23	M Bio Technology Inc.	Impfstoff für mykoplasmen-infektionen
RU2409668C1 (ru) *	2009-09-02	2011-01-20	Александр Анатольевич Ярославов	Способ получения иммобилизованных бислойных везикул
KR20110068831A (ko)	2009-12-16	2011-06-22	재단법인 전라남도생물산업진흥재단	리포좀 조성물, 그 제조방법, 및 폐렴 백신으로서의 그 용도
FR2958851B1 (fr) *	2010-04-16	2012-06-29	Xeda International	Nouvelles formulations d'ingredient(s) actif(s) d'origine vegetale ou leurs analogues synthetiques ou d'extrait(s) d'origine vegetale les contenant, et de lecithine
ES2631556T3 (es) *	2011-01-04	2017-09-01	Archivel Farma, Sl	Formulación de liposomas adecuada para tratar o prevenir la tuberculosis
DK2768484T3 (da)	2011-10-21	2019-10-07	Jazz Pharmaceuticals Res Llc	Lyofiliserede liposomer
PL2802345T3 (pl)	2012-01-12	2018-08-31	Archivel Farma, S.L.	Szczepionka mtb-c przeciw reakcjom alergicznym
EA023079B1 (ru) *	2012-12-24	2016-04-29	Общество С Ограниченной Ответственностью "Технология Лекарств"	Способ получения липосомальной формы иринотекана (варианты)
JP6866060B2 (ja) *	2014-10-27	2021-04-28	花王株式会社	精製茶抽出物の製造方法
JP6533297B2 (ja) *	2014-12-30	2019-06-19	セルトリオン・インコーポレイテッド	表皮成長因子とリポソームのハイブリッド型多層ナノ構造体及びその製造方法
EP3302432A4 (de) *	2015-05-27	2018-12-12	Nuvox Pharma LLC	Behandlung von akuten komplikationen bei sichelzellanämie
JP7014721B2 (ja) *	2015-09-18	2022-02-01	ディーエヌエーアールエックス	インビボでの核酸発現のためのシステム及び方法
MX382522B (es)	2015-10-16	2025-03-13	Ipsen Biopharm Ltd	Composiciones farmaceuticas estabilizantes de camptotecina.
JP2020511521A (ja)	2017-03-23	2020-04-16	ディーエヌエーアールエックス	ｉｎｖｉｖｏでの核酸発現のためのシステム及び方法
GB201707700D0 (en)	2017-05-12	2017-06-28	Glaxosmithkline Biologicals Sa	Dried composition
RU2697802C1 (ru) *	2018-08-23	2019-08-20	Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран)	Способ получения магнитных липосом

Family Cites Families (19)

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US4880635B1 (en) *	1984-08-08	1996-07-02	Liposome Company	Dehydrated liposomes
US4857319A (en) *	1985-01-11	1989-08-15	The Regents Of The University Of California	Method for preserving liposomes
AU587600B2 (en) *	1985-01-11	1989-08-24	Regents Of The University Of California, The	Method for preserving liposomes
CA1256372A (en) *	1985-04-11	1989-06-27	Koichiro Miyazima	Process for producing liposome composition
US5094785A (en) *	1986-12-10	1992-03-10	Ciba Corning Diagnostics Corp.	Process for stabilizing liposomes
CA1321351C (en) *	1987-02-23	1993-08-17	Helmut Otmar Hauser	Method of dehydrating vesicle preparations for long-term storage
US5089181A (en) *	1987-02-24	1992-02-18	Vestar, Inc.	Method of dehydrating vesicle preparations for long term storage
MX9203808A (es) *	1987-03-05	1992-07-01	Liposome Co Inc	Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
JP2780755B2 (ja) *	1987-05-22	1998-07-30	ザリポソームカンパニー，インコーポレイテッド	プロスタグランジン‐脂質製剤
EP0437479B1 (de) *	1988-10-05	1994-06-22	Vestar, Inc.	Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens
RU2014071C1 (ru) *	1991-03-26	1994-06-15	Научно-производственный центр медицинской биотехнологии	Способ получения липосом, содержащих водорастворимые низкомолекулярные соединения
US5958881A (en) *	1991-04-25	1999-09-28	Korman; Louis Y.	Composition containing VIP for injection and a method of enhancing visualization of tissues during medical procedures
WO1993020802A1 (en) *	1992-04-09	1993-10-28	Northwestern University	Acoustically reflective liposomes and methods to make and use the same
ES2115343T3 (es) *	1993-11-05	1998-06-16	Amgen Inc	Metodo de preparacion de liposomas y encapsulacion de material.
WO1997035561A1 (en)	1996-03-28	1997-10-02	The Board Of Trustees Of The University Of Illinois	Materials and methods for making improved liposome compositions
CA2202103C (en) *	1996-04-11	2007-01-09	Toshiaki Tagawa	Method for preparing closed vesicles
JP3693209B2 (ja) *	1996-04-11	2005-09-07	三菱化学株式会社	閉鎖小胞の製造方法
RU2123328C1 (ru) *	1996-04-19	1998-12-20	Государственный научный центр вирусологии и биотехнологии "Вектор"	Липосомальное противовирусное лекарственное средство для перорального применения
JP2000509404A (ja) *	1996-05-08	2000-07-25	ニカヘルスプロダクツリミテッド	遺伝物質の導入システムとしてのカチオン性ヴィロソーム

1998
- 1998-06-18 GB GBGB9813100.6A patent/GB9813100D0/en not_active Ceased
1999
- 1999-06-16 DE DE69923315T patent/DE69923315T2/de not_active Expired - Lifetime
- 1999-06-16 RU RU2001101910/14A patent/RU2216315C2/ru active
- 1999-06-16 CN CN99809563A patent/CN1312707A/zh active Pending
- 1999-06-16 WO PCT/GB1999/001911 patent/WO1999065465A1/en not_active Ceased
- 1999-06-16 EP EP99928051A patent/EP1087754B1/de not_active Expired - Lifetime
- 1999-06-16 AT AT99928051T patent/ATE287258T1/de not_active IP Right Cessation
- 1999-06-16 CA CA002335183A patent/CA2335183A1/en not_active Abandoned
- 1999-06-16 AU AU45180/99A patent/AU749499B2/en not_active Expired
- 1999-06-16 US US09/719,795 patent/US9675554B1/en not_active Expired - Fee Related
- 1999-06-16 KR KR1020007014404A patent/KR100658956B1/ko not_active Expired - Lifetime
- 1999-06-16 JP JP2000554345A patent/JP4567882B2/ja not_active Expired - Lifetime
- 1999-06-16 NZ NZ508960A patent/NZ508960A/xx unknown
- 1999-06-16 GB GB0030767A patent/GB2354166B/en not_active Expired - Lifetime
2000
- 2000-12-14 ZA ZA200007505A patent/ZA200007507B/en unknown
- 2000-12-15 NO NO20006442A patent/NO20006442L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1087754B1 (de)	2005-01-19
WO1999065465A1 (en)	1999-12-23
DE69923315T2 (de)	2006-04-06
NO20006442D0 (no)	2000-12-15
KR20010053006A (ko)	2001-06-25
DE69923315D1 (de)	2005-02-24
GB2354166A (en)	2001-03-21
CN1312707A (zh)	2001-09-12
KR100658956B1 (ko)	2006-12-21
GB0030767D0 (en)	2001-01-31
NO20006442L (no)	2001-02-15
JP4567882B2 (ja)	2010-10-20
CA2335183A1 (en)	1999-12-23
RU2216315C2 (ru)	2003-11-20
AU749499B2 (en)	2002-06-27
JP2003513003A (ja)	2003-04-08
ZA200007507B (en)	2002-03-14
GB2354166B (en)	2003-09-10
GB9813100D0 (en)	1998-08-19
EP1087754A1 (de)	2001-04-04
AU4518099A (en)	2000-01-05
NZ508960A (en)	2002-11-26
US9675554B1 (en)	2017-06-13

Legal Events

Date	Code	Title	Description
2005-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE287258T1 (de)	2005-02-15	Verfahren zur herstellung von liposomen
CA2158207A1 (en)	1996-03-14	Continuous Chewing Gum Manufacturing Process Using Rework Gum
DE69414709D1 (de)	1998-12-24	Liposomale antisense methylphosphonat oligo-nukleotide und verfahren zu deren herstellung sowie deren verwendung
DE59408535D1 (de)	1999-09-02	Dekorierte Keramik- und Glaserzeugnisse, Verfahren zu deren Herstellung und keramische Farbzusammensetzungen zur Durchführung des Verfahrens
DE69130647D1 (de)	1999-01-28	Verfahren zur herstellung von oligonukleotiden mit regellosen codonen
DE3689195D1 (de)	1993-11-25	Verfahren zur Herstellung von Aloe-Erzeugnissen, Erzeugnisse und Zusammensetzungen dazu.
DE69718942D1 (de)	2003-03-13	Verfahren zur herstellung von erythromicin a-oxim
CA2429412A1 (en)	2002-05-30	Production of fine-grained particles
DE69530242D1 (de)	2003-05-15	Verfahren zur Herstellung von Glutaminsäure durch Fermentation
CA2284544A1 (en)	1998-10-15	Method for modifying papermaking sludge and products made therefrom
DE69005711D1 (de)	1994-02-17	Verfahren zur Herstellung von P-Typ-II-VI-Halbleitern.
ATE83605T1 (de)	1993-01-15	Pestizide zusammensetzungen und verfahren zu ihrer herstellung.
DE3763074D1 (de)	1990-07-12	Diperoxysaeure-vorlaeufer, verfahren zu deren herstellung und deren verwendung in bleichmittelzusammensetzungen.
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DE69308531D1 (de)	1997-04-10	Cycloisomaltooligosaccharide; Enzym und Verfahren zu ihrer Herstellung, und Verfahren zur Herstellung von dem Enzym
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IT8919477A0 (it)	1989-02-17	Processo per la preparazione di 1,4 diidropiridine polisostituite in forma enantiomericamente pura.
DE3764981D1 (de)	1990-10-25	Gefrorene hefe in form von frei fliessenden teilchen, verfahren zu deren herstellung und verwendung dieser hefen in gefrorenen teigen.
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DE3863387D1 (de)	1991-08-01	In form eines granulats vorliegendes substanzgemisch zur zubereitung von dialyseloesungen, verfahren zu seiner herstellung.
FI971031A7 (fi)	1997-03-12	Purukumin jatkuvatoiminen valmistus kumipohjakonsentraatista
DE69631602D1 (de)	2004-03-25	Wässrige dispersionen von polyamiden
DE59605774D1 (de)	2000-09-28	Verfahren zur Herstellung von beta-Carotin-Präparaten mit hohem 9(Z)-Gehalt