ATE287258T1 - Verfahren zur herstellung von liposomen - Google Patents

Verfahren zur herstellung von liposomen

Info

Publication number: ATE287258T1
Authority: AT; Austria
Prior art keywords: liposomes; compositions; producing liposomes; regent; pharmaceuticals
Prior art date: 1998-06-18

Application number

AT99928051T

Other languages

English (en)

Inventor

Gregory Gregoriadis

Brahim Zadi

Pramukh Nalaka Jayasekera

Original Assignee

Secr Defence

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-18

Filing date

1999-06-16

Publication date

2005-02-15

1999-06-16 Application filed by Secr Defence filed Critical Secr Defence

2005-02-15 Application granted granted Critical

2005-02-15 Publication of ATE287258T1 publication Critical patent/ATE287258T1/de

Links

239000002502 liposome Substances 0.000 title abstract 4
238000004519 manufacturing process Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 3
238000000034 method Methods 0.000 abstract 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000001035 drying Methods 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Manufacturing Of Micro-Capsules (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT99928051T 1998-06-18 1999-06-16 Verfahren zur herstellung von liposomen ATE287258T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9813100.6A GB9813100D0 (en)	1998-06-18	1998-06-18	Method of forming liposomes
PCT/GB1999/001911 WO1999065465A1 (en)	1998-06-18	1999-06-16	Method of forming liposomes

Publications (1)

Publication Number	Publication Date
ATE287258T1 true ATE287258T1 (de)	2005-02-15

Family

ID=10833946

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99928051T ATE287258T1 (de)	1998-06-18	1999-06-16	Verfahren zur herstellung von liposomen

Country Status (15)

Country	Link
US (1)	US9675554B1 (de)
EP (1)	EP1087754B1 (de)
JP (1)	JP4567882B2 (de)
KR (1)	KR100658956B1 (de)
CN (1)	CN1312707A (de)
AT (1)	ATE287258T1 (de)
AU (1)	AU749499B2 (de)
CA (1)	CA2335183A1 (de)
DE (1)	DE69923315T2 (de)
GB (2)	GB9813100D0 (de)
NO (1)	NO20006442L (de)
NZ (1)	NZ508960A (de)
RU (1)	RU2216315C2 (de)
WO (1)	WO1999065465A1 (de)
ZA (1)	ZA200007507B (de)

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KR20060123170A (ko) *	2003-10-24	2006-12-01	알자 코포레이션	지질 입자의 제조방법
CA2821167C (en)	2004-05-03	2016-06-28	Merrimack Pharmaceuticals, Inc.	Drug delivery liposomes containing anionic polyols or anionic sugars
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JP5279497B2 (ja)	2005-09-30	2013-09-04	リポクセンテクノロジーズリミテッド	多糖抗原及びタンパク質アジュバントを含むリポソームワクチン組成物
RU2300369C1 (ru) *	2005-12-27	2007-06-10	Наталья Ивановна Ларионова	Способ получения полиэлектролитных микрочастиц, содержащих инкапсулируемое вещество, чувствительных к изменению состава окружающей среды
EP2492278A1 (de)	2006-09-18	2012-08-29	Compugen Ltd.	Antikörper gegen einen Agonisten von G-Protein-gekoppelten Rezeptoren und deren Verwendung in Diagnose und Therapie
AU2008273813B2 (en)	2007-07-12	2013-06-13	Compugen Ltd.	Bioactive peptides and method of using same
JP5362998B2 (ja) *	2008-01-10	2013-12-11	第一ファインケミカル株式会社	乾燥リポソーム製剤
US9445975B2 (en)	2008-10-03	2016-09-20	Access Business Group International, Llc	Composition and method for preparing stable unilamellar liposomal suspension
AU2009302042A1 (en)	2008-10-07	2010-04-15	Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd.	Liposomal systems comprising sphingomyelin
EP2184054A1 (de)	2008-11-08	2010-05-12	Lipoxen Technologies Limited	SiRNA-Abgabe
WO2010140377A1 (ja) *	2009-06-04	2010-12-09	独立行政法人産業技術総合研究所	マイコプラズマ感染症用ワクチン
RU2409668C1 (ru) *	2009-09-02	2011-01-20	Александр Анатольевич Ярославов	Способ получения иммобилизованных бислойных везикул
KR20110068831A (ko)	2009-12-16	2011-06-22	재단법인 전라남도생물산업진흥재단	리포좀 조성물, 그 제조방법, 및 폐렴 백신으로서의 그 용도
FR2958851B1 (fr) *	2010-04-16	2012-06-29	Xeda International	Nouvelles formulations d'ingredient(s) actif(s) d'origine vegetale ou leurs analogues synthetiques ou d'extrait(s) d'origine vegetale les contenant, et de lecithine
CN107296793A (zh)	2011-01-04	2017-10-27	阿尔西维尔法尔玛公司	适于治疗或预防结核的脂质体制剂
KR102284689B1 (ko)	2011-10-21	2021-08-02	셀라토 파마슈티칼즈, 인코포레이티드	동결건조된 리포좀
BR112014017217B1 (pt)	2012-01-12	2023-01-17	Archivel Farma, S.L	Agente e composição farmacêutica
EA023079B1 (ru) *	2012-12-24	2016-04-29	Общество С Ограниченной Ответственностью "Технология Лекарств"	Способ получения липосомальной формы иринотекана (варианты)
JP6866060B2 (ja) *	2014-10-27	2021-04-28	花王株式会社	精製茶抽出物の製造方法
CN107106421B (zh) *	2014-12-30	2020-10-27	赛特瑞恩股份有限公司	表皮生长因子和脂质体的混合型多层纳米结构及其制造方法
CA2987049A1 (en) *	2015-05-27	2016-12-01	Nuvox Pharma Llc	Treatment of acute complications of sickle cell disease
EP3349730B1 (de)	2015-09-18	2020-12-02	Dnarx	Systeme zur in-vivo-nukleinsäureexpression
AU2016340153B2 (en)	2015-10-16	2022-06-02	Ipsen Biopharm Ltd.	Stabilizing camptothecin pharmaceutical compositions
CN116392609A (zh)	2017-03-23	2023-07-07	Dnarx公司	用于体内核酸表达的系统和方法
GB201707700D0 (en)	2017-05-12	2017-06-28	Glaxosmithkline Biologicals Sa	Dried composition
RU2697802C1 (ru) *	2018-08-23	2019-08-20	Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран)	Способ получения магнитных липосом

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JP2780755B2 (ja) *	1987-05-22	1998-07-30	ザリポソームカンパニー，インコーポレイテッド	プロスタグランジン‐脂質製剤
JP2792702B2 (ja) *	1988-10-05	1998-09-03	ネクスター・フアーマシユーテイカルズ・インコーポレイテツド	乾燥時に改善された安定性を示すリポソームの調製方法
RU2014071C1 (ru) *	1991-03-26	1994-06-15	Научно-производственный центр медицинской биотехнологии	Способ получения липосом, содержащих водорастворимые низкомолекулярные соединения
US5958881A (en) *	1991-04-25	1999-09-28	Korman; Louis Y.	Composition containing VIP for injection and a method of enhancing visualization of tissues during medical procedures
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AU710170B2 (en) *	1996-05-08	1999-09-16	Nika Health Products Limited	Cationic virosomes as transfer system for genetic material

1998
- 1998-06-18 GB GBGB9813100.6A patent/GB9813100D0/en not_active Ceased
1999
- 1999-06-16 NZ NZ508960A patent/NZ508960A/xx unknown
- 1999-06-16 DE DE69923315T patent/DE69923315T2/de not_active Expired - Lifetime
- 1999-06-16 RU RU2001101910/14A patent/RU2216315C2/ru active
- 1999-06-16 AU AU45180/99A patent/AU749499B2/en not_active Expired
- 1999-06-16 EP EP99928051A patent/EP1087754B1/de not_active Expired - Lifetime
- 1999-06-16 WO PCT/GB1999/001911 patent/WO1999065465A1/en not_active Ceased
- 1999-06-16 CA CA002335183A patent/CA2335183A1/en not_active Abandoned
- 1999-06-16 KR KR1020007014404A patent/KR100658956B1/ko not_active Expired - Lifetime
- 1999-06-16 GB GB0030767A patent/GB2354166B/en not_active Expired - Lifetime
- 1999-06-16 US US09/719,795 patent/US9675554B1/en not_active Expired - Fee Related
- 1999-06-16 JP JP2000554345A patent/JP4567882B2/ja not_active Expired - Lifetime
- 1999-06-16 AT AT99928051T patent/ATE287258T1/de not_active IP Right Cessation
- 1999-06-16 CN CN99809563A patent/CN1312707A/zh active Pending
2000
- 2000-12-14 ZA ZA200007505A patent/ZA200007507B/en unknown
- 2000-12-15 NO NO20006442A patent/NO20006442L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20010053006A (ko)	2001-06-25
GB0030767D0 (en)	2001-01-31
CA2335183A1 (en)	1999-12-23
GB9813100D0 (en)	1998-08-19
NO20006442L (no)	2001-02-15
CN1312707A (zh)	2001-09-12
KR100658956B1 (ko)	2006-12-21
GB2354166B (en)	2003-09-10
NO20006442D0 (no)	2000-12-15
DE69923315D1 (de)	2005-02-24
US9675554B1 (en)	2017-06-13
WO1999065465A1 (en)	1999-12-23
AU749499B2 (en)	2002-06-27
NZ508960A (en)	2002-11-26
ZA200007507B (en)	2002-03-14
JP4567882B2 (ja)	2010-10-20
GB2354166A (en)	2001-03-21
EP1087754B1 (de)	2005-01-19
AU4518099A (en)	2000-01-05
EP1087754A1 (de)	2001-04-04
JP2003513003A (ja)	2003-04-08
RU2216315C2 (ru)	2003-11-20
DE69923315T2 (de)	2006-04-06

Legal Events

Date	Code	Title	Description
2005-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69923315D1 (de)	2005-02-24	Verfahren zur herstellung von liposomen
ATE180508T1 (de)	1999-06-15	Verfahren zur herstellung von teilchen enthaltend lactambleich mittelaktivator
CA2158207A1 (en)	1996-03-14	Continuous Chewing Gum Manufacturing Process Using Rework Gum
ATE173397T1 (de)	1998-12-15	Liposomale antisense methylphosphonat oligo- nukleotide und verfahren zu deren herstellung sowie deren verwendung
DE3689195D1 (de)	1993-11-25	Verfahren zur Herstellung von Aloe-Erzeugnissen, Erzeugnisse und Zusammensetzungen dazu.
DE69718942D1 (de)	2003-03-13	Verfahren zur herstellung von erythromicin a-oxim
DE69530242D1 (de)	2003-05-15	Verfahren zur Herstellung von Glutaminsäure durch Fermentation
DE69115715D1 (de)	1996-02-01	Gemischte, phosphor und schwefel enthaltende reaktionsprodukte, hergestellt unter niedrigem druck, verwendbar in kraftübertragungszusammensetzungen und verfahren zu deren herstellung
DE69415327D1 (de)	1999-01-28	Verfahren zur herstellung von detergensagglomeraten von hoher dichte
DE69005711D1 (de)	1994-02-17	Verfahren zur Herstellung von P-Typ-II-VI-Halbleitern.
DE69629299D1 (de)	2003-09-04	Prozess für die produktion von l-lysin durch fermentation
DE69007800D1 (de)	1994-05-11	Verfahren zur fermentativen Herstellung von L-Arginin.
EP0574685A3 (de)	1995-05-31	Verfahren zur Herstellung von Waschmittelbuildermischungen unter Verwendung von sprühgranulierter Zitronensäure und ihrer Salze.
EP1004638A3 (de)	2000-10-18	Wässriges Anstrichmittel, Verfahren zu seiner Herstellung und Kit zur Verwendung in diesem Verfahren
DE69808086D1 (de)	2002-10-24	Ein verfahren zur herstellung von 1,4,7,10-tetraazacyclododecan-1,4,7-triessigsäure und deren derivaten
DE69925992D1 (de)	2005-08-04	VERFAHREN ZUR HERSTELLUNG VON 5-HYDROXYBENZO[b]THIOPHEN-3-CARBONSÄURE
ATE299858T1 (de)	2005-08-15	Verfahren zur herstellung von diaminodiphenylmethan und seiner höheren homologen
IT8919477A0 (it)	1989-02-17	Processo per la preparazione di 1,4 diidropiridine polisostituite in forma enantiomericamente pura.
DE69615204D1 (de)	2001-10-18	Verfahren zur herstellung von kaliumclavulanat
DE59605774D1 (de)	2000-09-28	Verfahren zur Herstellung von beta-Carotin-Präparaten mit hohem 9(Z)-Gehalt
ATE299851T1 (de)	2005-08-15	Verfahren zur herstellung von zwischenprodukten
DE59803194D1 (de)	2002-04-04	Verfahren zur herstellung von 1,3-disubstituierten 2-nitroguanidinen
DE3762636D1 (de)	1990-06-13	Verfahren zur herstellung von alkalilauge ohne sulfidinhalt.
CA2317018A1 (en)	2001-03-02	High performance titanium dioxide clouding agent and method of manufacture thereof
DE3781095D1 (de)	1992-09-17	Calciumhypochloritzusammensetzungen und verfahren zu ihrer herstellung.