ATE291624T1 - Ein proteinase inhibitor, vorläufer davon und genetische sequenzen dafür kodierend - Google Patents
Ein proteinase inhibitor, vorläufer davon und genetische sequenzen dafür kodierendInfo
- Publication number
- ATE291624T1 ATE291624T1 AT94902551T AT94902551T ATE291624T1 AT E291624 T1 ATE291624 T1 AT E291624T1 AT 94902551 T AT94902551 T AT 94902551T AT 94902551 T AT94902551 T AT 94902551T AT E291624 T1 ATE291624 T1 AT E291624T1
- Authority
- AT
- Austria
- Prior art keywords
- precursor
- genetic sequences
- proteinase inhibitor
- monomers
- sequences coding
- Prior art date
Links
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title abstract 5
- 239000002243 precursor Substances 0.000 title abstract 4
- 230000002068 genetic effect Effects 0.000 title abstract 2
- 239000000178 monomer Substances 0.000 abstract 3
- MTCFGRXMJLQNBG-UHFFFAOYSA-N serine Chemical compound OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 2
- 108090000317 Chymotrypsin Proteins 0.000 abstract 1
- 241001522306 Serinus serinus Species 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 229940019748 antifibrinolytic proteinase inhibitors Drugs 0.000 abstract 1
- 229960002376 chymotrypsin Drugs 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/06—Uses of viruses as vector in vitro
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPL639992 | 1992-12-16 | ||
| PCT/AU1993/000659 WO1994013810A1 (en) | 1992-12-16 | 1993-12-16 | A proteinase inhibitor, precursor thereof and genetic sequences encoding same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE291624T1 true ATE291624T1 (de) | 2005-04-15 |
Family
ID=3776602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94902551T ATE291624T1 (de) | 1992-12-16 | 1993-12-16 | Ein proteinase inhibitor, vorläufer davon und genetische sequenzen dafür kodierend |
Country Status (9)
| Country | Link |
|---|---|
| US (10) | US6031087A (de) |
| EP (1) | EP0674712B1 (de) |
| JP (3) | JP3657980B2 (de) |
| AT (1) | ATE291624T1 (de) |
| CA (1) | CA2151933C (de) |
| DE (1) | DE69333782T2 (de) |
| ES (1) | ES2239754T3 (de) |
| NZ (1) | NZ258824A (de) |
| WO (1) | WO1994013810A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE291624T1 (de) * | 1992-12-16 | 2005-04-15 | Hexima Ltd | Ein proteinase inhibitor, vorläufer davon und genetische sequenzen dafür kodierend |
| US6121436A (en) | 1996-12-13 | 2000-09-19 | Monsanto Company | Antifungal polypeptide and methods for controlling plant pathogenic fungi |
| GB9725556D0 (en) * | 1997-12-03 | 1998-02-04 | Ciba Geigy Ag | Organic compounds |
| EP0958833A1 (de) * | 1998-05-20 | 1999-11-24 | Erasmus Universiteit Rotterdam | Verfahren und Mittel zur Vorbeugung oder Behandlung der Entzündung |
| ATE510015T1 (de) * | 2001-02-08 | 2011-06-15 | Hexima Ltd | Aus pflanzen stammende moleküle und diese codierende genetische sequenzen sowie verwendungen dafür |
| AU2003286088A1 (en) * | 2002-11-29 | 2004-06-23 | The University Of Hong Kong | Genetically modified plants expressing proteinase inhibitors, sapina2a or sapin2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activities |
| CA2521940C (en) * | 2003-04-23 | 2010-01-26 | Latrobe University | Insect chymotrypsin and inhibitors thereof |
| US20060035827A1 (en) * | 2004-06-24 | 2006-02-16 | Green Gary M | Compositions and methods for the treatment or prevention of gallbladder disease |
| CA2614353A1 (en) * | 2005-07-08 | 2007-01-18 | Hexima Limited | Management of plant pathogens |
| NZ572795A (en) * | 2006-05-25 | 2011-06-30 | Hexima Ltd | Multi-gene expression vehicle |
| US20090083880A1 (en) * | 2007-04-20 | 2009-03-26 | Hexima Ltd. | Modified plant defensin |
| AR075257A1 (es) * | 2008-02-01 | 2011-03-23 | Hexima Ltd | Sistema de proteccion de plantas contra la infeccion por agentes patogenos |
| US9889184B2 (en) | 2008-08-05 | 2018-02-13 | Hexima Limited | Anti-pathogen systems |
| US20100095408A1 (en) * | 2008-08-05 | 2010-04-15 | Hexima Limited | Anti-Pathogen Systems |
| CA2825118C (en) | 2011-02-07 | 2020-02-18 | Hexima Limited | Modified plant defensins useful as anti-pathogenic agents |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI875467L (fi) * | 1986-12-19 | 1988-06-20 | Agricultural Genetics Co | Dna-molekyler, som aer nyttiga vid vaextskydd. |
| JPS6413997U (de) | 1987-07-17 | 1989-01-24 | ||
| JPS6453092A (en) | 1987-08-21 | 1989-03-01 | Hitachi Ltd | Blower device |
| US5032396A (en) * | 1989-02-17 | 1991-07-16 | Immunex Corporation | IL-7 to stimulate platelet production |
| DK0506868T4 (da) | 1989-12-22 | 2004-04-26 | Mikrogen Molekularbiol Entw | Immunologisk aktive proteiner fra Borrelia burgdorferi, tilhørende testkits og vaccine |
| ATE142420T1 (de) | 1990-05-25 | 1996-09-15 | Univ Washington | Verfahren zur auslösung pflanzenschützender mechanismen |
| JPH04145099A (ja) | 1990-10-05 | 1992-05-19 | Sanwa Kagaku Kenkyusho Co Ltd | Gip様活性を有するポリペプチド誘導体及びその用途 |
| GB9104617D0 (en) * | 1991-03-05 | 1991-04-17 | Nickerson Int Seed | Pest control |
| ATE291624T1 (de) * | 1992-12-16 | 2005-04-15 | Hexima Ltd | Ein proteinase inhibitor, vorläufer davon und genetische sequenzen dafür kodierend |
-
1993
- 1993-12-16 AT AT94902551T patent/ATE291624T1/de not_active IP Right Cessation
- 1993-12-16 NZ NZ258824A patent/NZ258824A/en not_active IP Right Cessation
- 1993-12-16 US US08/454,295 patent/US6031087A/en not_active Expired - Lifetime
- 1993-12-16 WO PCT/AU1993/000659 patent/WO1994013810A1/en not_active Ceased
- 1993-12-16 ES ES94902551T patent/ES2239754T3/es not_active Expired - Lifetime
- 1993-12-16 EP EP94902551A patent/EP0674712B1/de not_active Expired - Lifetime
- 1993-12-16 CA CA002151933A patent/CA2151933C/en not_active Expired - Fee Related
- 1993-12-16 DE DE69333782T patent/DE69333782T2/de not_active Expired - Lifetime
- 1993-12-16 JP JP51358394A patent/JP3657980B2/ja not_active Expired - Fee Related
-
1999
- 1999-05-10 JP JP11128615A patent/JPH11346788A/ja not_active Withdrawn
- 1999-11-01 US US09/431,499 patent/US6451573B1/en not_active Expired - Fee Related
- 1999-11-01 US US09/431,500 patent/US6261821B1/en not_active Expired - Lifetime
- 1999-11-01 US US09/431,498 patent/US6440727B1/en not_active Expired - Fee Related
-
2000
- 2000-01-12 JP JP2000003716A patent/JP4115642B2/ja not_active Expired - Fee Related
-
2001
- 2001-03-20 US US09/812,502 patent/US6806074B2/en not_active Expired - Fee Related
-
2002
- 2002-05-29 US US10/157,622 patent/US6946278B2/en not_active Expired - Fee Related
- 2002-06-07 US US10/164,961 patent/US6955916B2/en not_active Expired - Fee Related
-
2005
- 2005-07-11 US US11/178,737 patent/US7309596B2/en not_active Expired - Fee Related
-
2006
- 2006-11-13 US US11/598,414 patent/US7410796B2/en not_active Expired - Fee Related
-
2007
- 2007-10-31 US US11/981,436 patent/US20080134367A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69333782D1 (de) | 2005-04-28 |
| NZ258824A (en) | 1997-11-24 |
| JPH11346788A (ja) | 1999-12-21 |
| US6806074B2 (en) | 2004-10-19 |
| JP2000175581A (ja) | 2000-06-27 |
| CA2151933A1 (en) | 1994-06-23 |
| WO1994013810A1 (en) | 1994-06-23 |
| US20030096388A1 (en) | 2003-05-22 |
| JP3657980B2 (ja) | 2005-06-08 |
| US20070054365A1 (en) | 2007-03-08 |
| US20080134367A1 (en) | 2008-06-05 |
| ES2239754T3 (es) | 2005-10-01 |
| DE69333782T2 (de) | 2006-01-26 |
| US20030129720A1 (en) | 2003-07-10 |
| US6031087A (en) | 2000-02-29 |
| JPH08506482A (ja) | 1996-07-16 |
| US7309596B2 (en) | 2007-12-18 |
| US20050250149A1 (en) | 2005-11-10 |
| US6451573B1 (en) | 2002-09-17 |
| US7410796B2 (en) | 2008-08-12 |
| US20030027303A1 (en) | 2003-02-06 |
| EP0674712A1 (de) | 1995-10-04 |
| EP0674712A4 (de) | 1997-06-18 |
| JP4115642B2 (ja) | 2008-07-09 |
| EP0674712B1 (de) | 2005-03-23 |
| US6440727B1 (en) | 2002-08-27 |
| US6955916B2 (en) | 2005-10-18 |
| US6261821B1 (en) | 2001-07-17 |
| CA2151933C (en) | 2007-04-24 |
| US6946278B2 (en) | 2005-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |