ATE292131T1 - Zwischenprodukt zur herstellung von d-chiro- inosose und (+)-d-chiro-inositol - Google Patents

Zwischenprodukt zur herstellung von d-chiro- inosose und (+)-d-chiro-inositol

Info

Publication number
ATE292131T1
ATE292131T1 AT02007823T AT02007823T ATE292131T1 AT E292131 T1 ATE292131 T1 AT E292131T1 AT 02007823 T AT02007823 T AT 02007823T AT 02007823 T AT02007823 T AT 02007823T AT E292131 T1 ATE292131 T1 AT E292131T1
Authority
AT
Austria
Prior art keywords
chiro
inosose
inositol
compounds
synthesis
Prior art date
Application number
AT02007823T
Other languages
English (en)
Inventor
Tomas Hudlicky
Martin Mandel
Original Assignee
Virginia Tech Intell Prop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Tech Intell Prop filed Critical Virginia Tech Intell Prop
Application granted granted Critical
Publication of ATE292131T1 publication Critical patent/ATE292131T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/02Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
    • C07C35/08Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings
    • C07C35/14Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings with more than one hydroxy group bound to the ring
    • C07C35/16Inositols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02007823T 1992-10-05 1993-09-23 Zwischenprodukt zur herstellung von d-chiro- inosose und (+)-d-chiro-inositol ATE292131T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95652292A 1992-10-05 1992-10-05
US97405792A 1992-11-10 1992-11-10

Publications (1)

Publication Number Publication Date
ATE292131T1 true ATE292131T1 (de) 2005-04-15

Family

ID=27130376

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02007823T ATE292131T1 (de) 1992-10-05 1993-09-23 Zwischenprodukt zur herstellung von d-chiro- inosose und (+)-d-chiro-inositol

Country Status (11)

Country Link
US (6) US5563281A (de)
EP (2) EP0663915B1 (de)
JP (1) JP4242925B2 (de)
AT (1) ATE292131T1 (de)
AU (1) AU693075B2 (de)
CA (1) CA2146353C (de)
DE (2) DE69333788T2 (de)
DK (1) DK1225175T3 (de)
MX (1) MX9306095A (de)
NZ (3) NZ314111A (de)
WO (1) WO1994007897A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5442079A (en) * 1993-05-10 1995-08-15 Virginia Polytechnic Institute And State University Method for preparing erythruronolactone
JP2001163810A (ja) * 1999-09-30 2001-06-19 Microbial Chem Res Found 1d−キロ−イノシトールの新規合成方法および中間体
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
EP1824496A4 (de) * 2004-11-17 2008-07-16 Joanne Mclaurin Zusammensetzungen aus scyllo-inositol-derivaten und verfahren zur behandlung von störungen der proteinaggregation
WO2007041855A1 (en) * 2005-10-13 2007-04-19 Waratah Pharmaceuticals, Inc. Scyllo-inositol derivatives and their use in the treatment of diseases characterised by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence
US20070197452A1 (en) * 2006-02-17 2007-08-23 Mclaurin Joanne Treatment of amyloid-related diseases
CN103054837A (zh) * 2006-03-09 2013-04-24 瓦拉塔药品公司 用于治疗蛋白积聚病症的环己烷多元醇制剂
US20110028719A1 (en) * 2006-05-19 2011-02-03 Jacek Slon-Usakiewicz Screening methods for amyloid beta modulators
US20100173960A1 (en) * 2006-09-21 2010-07-08 Antonio Cruz The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases
US20090214474A1 (en) * 2006-11-01 2009-08-27 Barbara Brooke Jennings Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
KR100748210B1 (ko) * 2006-11-21 2007-08-09 주식회사 카이로켐 디-카이로-이노시톨의 제조방법
WO2008061373A1 (en) * 2006-11-24 2008-05-29 Waratah Pharmaceuticals Inc. Combination treatments for alzheimer's disease and similar diseases
CA2683546A1 (en) * 2007-04-12 2008-10-23 Joanne Mclaurin Use of cyclohexanehexol derivatives in the treatment of .alpha.-synucleinopathies
CA2683580A1 (en) * 2007-04-12 2008-10-23 Joanne Mclaurin Treatment of amyotrophic lateral sclerosis
JP2010523602A (ja) * 2007-04-12 2010-07-15 ワラタ ファーマシューティカルズ, インコーポレイテッド 眼疾患の治療におけるシクロヘキサンヘキソール誘導体の使用
WO2008124930A1 (en) * 2007-04-12 2008-10-23 Joanne Mclaurin Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
CA2740124A1 (en) * 2008-10-09 2010-04-15 Waratah Pharmaceuticals Inc. Use of scyllo-inositols for the treatment of macular degeneration-related disorders
DE102014006563B4 (de) * 2014-05-07 2017-05-11 Nb Technologies Gmbh Imprintstempel sowie Verfahren zur Herstellung und Anwendung eines Imprintstempels

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3065636B2 (ja) * 1989-06-29 2000-07-17 塩野義製薬株式会社 [ジ―tert―ブチル(ヒドロキシ)フェニルチオ]置換ヒドロキサム酸誘導体
US5200516A (en) * 1990-02-16 1993-04-06 Virginia Tech Intellectual Properties Synthesis of sugars from substituted and unsubstituted arene diols
EP0477359B1 (de) * 1990-04-16 1995-07-05 Virginia Tech Intellectual Properties, Inc. Synthese ion cyclitolen aus substituierten arendiolen
US5091596A (en) * 1990-12-20 1992-02-25 Univ. Of Va. Alumni Patents Foundation Method for producing chiro-inositol

Also Published As

Publication number Publication date
US5600014A (en) 1997-02-04
US5578738A (en) 1996-11-26
EP0663915A1 (de) 1995-07-26
DE69332542T2 (de) 2003-08-14
DE69333788T2 (de) 2006-02-16
CA2146353C (en) 2007-04-17
US5602263A (en) 1997-02-11
CA2146353A1 (en) 1994-04-14
NZ314111A (en) 1997-08-22
AU693075B2 (en) 1998-06-25
NZ314112A (en) 1997-08-22
NZ256610A (en) 1997-03-24
WO1994007897A1 (en) 1994-04-14
AU5139393A (en) 1994-04-26
MX9306095A (es) 1994-06-30
US5563281A (en) 1996-10-08
US5633412A (en) 1997-05-27
DE69332542D1 (de) 2003-01-16
EP1225175B1 (de) 2005-03-30
DE69333788D1 (de) 2005-05-04
EP1225175A1 (de) 2002-07-24
JP4242925B2 (ja) 2009-03-25
US5602287A (en) 1997-02-11
DK1225175T3 (da) 2005-06-20
JPH08502255A (ja) 1996-03-12
EP0663915B1 (de) 2002-12-04

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