ATE297995T1 - Aussermembranproteine, ihre gene, und deren verwendung - Google Patents

Aussermembranproteine, ihre gene, und deren verwendung

Info

Publication number
ATE297995T1
ATE297995T1 AT99962421T AT99962421T ATE297995T1 AT E297995 T1 ATE297995 T1 AT E297995T1 AT 99962421 T AT99962421 T AT 99962421T AT 99962421 T AT99962421 T AT 99962421T AT E297995 T1 ATE297995 T1 AT E297995T1
Authority
AT
Austria
Prior art keywords
genes
extra
membrane proteins
proteins
membrane
Prior art date
Application number
AT99962421T
Other languages
English (en)
Inventor
Martin J G Hughes
Joseph D Santangelo
Jonathan D Lane
Robert Feldman
Joanne C Moore
Paul Everest
Richard J Dobson
Caroline Joanne Henwood
Gordon Dougan
Rebecca Kerry Wilson
Original Assignee
Microscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9828346.8A external-priority patent/GB9828346D0/en
Priority claimed from GBGB9901233.8A external-priority patent/GB9901233D0/en
Priority claimed from GBGB9901234.6A external-priority patent/GB9901234D0/en
Priority claimed from GBGB9908321.4A external-priority patent/GB9908321D0/en
Priority claimed from GBGB9912036.2A external-priority patent/GB9912036D0/en
Priority claimed from GBGB9922596.3A external-priority patent/GB9922596D0/en
Application filed by Microscience Ltd filed Critical Microscience Ltd
Application granted granted Critical
Publication of ATE297995T1 publication Critical patent/ATE297995T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1018—Carboxy- and carbamoyl transferases (2.1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99962421T 1998-12-22 1999-12-22 Aussermembranproteine, ihre gene, und deren verwendung ATE297995T1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9828346.8A GB9828346D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9901233.8A GB9901233D0 (en) 1999-01-20 1999-01-20 Protein and compositions containing it
GBGB9901234.6A GB9901234D0 (en) 1999-01-20 1999-01-20 Protein and compositions containing it
GBGB9908321.4A GB9908321D0 (en) 1999-04-12 1999-04-12 Purine nucleoside phosphatase and compositions containing it
GBGB9912036.2A GB9912036D0 (en) 1999-05-24 1999-05-24 Glucose-6-phosphate isomerase and compositions containing it
GBGB9922596.3A GB9922596D0 (en) 1999-09-23 1999-09-23 Protein and compositions containing it
PCT/GB1999/004376 WO2000037490A2 (en) 1998-12-22 1999-12-22 Outer surface proteins, their genes, and their use

Publications (1)

Publication Number Publication Date
ATE297995T1 true ATE297995T1 (de) 2005-07-15

Family

ID=27547330

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99962421T ATE297995T1 (de) 1998-12-22 1999-12-22 Aussermembranproteine, ihre gene, und deren verwendung

Country Status (23)

Country Link
US (3) US7217415B1 (de)
EP (2) EP1140994B1 (de)
JP (1) JP2002533065A (de)
KR (4) KR100866170B1 (de)
CN (3) CN1733800A (de)
AP (1) AP2006003504A0 (de)
AT (1) ATE297995T1 (de)
AU (1) AU758722B2 (de)
BR (1) BR9916473A (de)
CA (1) CA2354843A1 (de)
CZ (1) CZ20012174A3 (de)
DE (1) DE69925866T2 (de)
DK (1) DK1140994T3 (de)
EA (1) EA009885B1 (de)
ES (1) ES2241352T3 (de)
HU (1) HUP0201022A3 (de)
NO (1) NO20013101L (de)
NZ (4) NZ525538A (de)
OA (1) OA12425A (de)
PL (1) PL351027A1 (de)
PT (1) PT1140994E (de)
SI (1) SI1140994T1 (de)
WO (1) WO2000037490A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2354843A1 (en) * 1998-12-22 2000-06-29 Microscience Limited Outer surface proteins, their genes, and their use
CN101066447A (zh) * 1998-12-22 2007-11-07 微科学有限公司 基因和蛋白质,及它们的用途
US6890539B2 (en) * 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
WO2008152448A2 (en) * 2006-12-21 2008-12-18 Emergent Product Development Uk Limited Streptococcus proteins, and their use in vaccination
CN103060284A (zh) * 2012-10-31 2013-04-24 内蒙古民族大学 一种无乳链球菌pgk亚单位重组蛋白及其制备方法
CN110669711A (zh) * 2019-08-09 2020-01-10 中国水产科学研究院珠江水产研究所 基于pgk基因的重组乳酸乳球菌和无乳链球菌病疫苗

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230777B1 (de) * 1985-12-28 1991-04-10 Ohgen Research Laboratories Ltd., Antitumorprotein-Gen von Streptococcus pyogenes SU, Plasmide, die das Gen enthalten, Transformantenzellen, die die Plasmide beherbergen, und Verfahren zur Herstellung des Antitumorproteins
US5328996A (en) * 1989-03-29 1994-07-12 University Of Florida Research Foundation, Inc. Bacterial plasmin receptors as fibrinolytic agents
EP0672123A1 (de) * 1992-01-08 1995-09-20 The Rockefeller University Multifunktionale Oberflächeprotein von Streptokokken
IL107458A0 (en) * 1992-11-02 1994-02-27 Gen Hospital Corp Conjugate vaccine against group b streptococcus
US6015889A (en) * 1993-03-19 2000-01-18 Gunnar Lindahl Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
HU217582B (hu) * 1993-03-19 2000-02-28 Gunnar Lindahl Streptococcus B csoportba tartozó törzsek elleni immunitást biztosító, Rib fehérjenevű felületi protein, eljárás a protein tisztítására, reagenskészlet és gyógyszerkészítmény
US6346392B1 (en) * 1996-11-27 2002-02-12 Smithkline Beecham Corporation Polynucleotides encoding a novel glutamine transport ATP-binding protein
JP4469026B2 (ja) * 1996-10-31 2010-05-26 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅの抗原およびワクチン
US7196164B2 (en) * 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
US7115731B1 (en) * 1997-07-02 2006-10-03 sanofi pasteur limited/ sanofi pasteur limiteé Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6380370B1 (en) * 1997-08-14 2002-04-30 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
US6165763A (en) * 1997-10-30 2000-12-26 Smithkline Beecham Corporation Ornithine carbamoyltransferase
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
CN101066447A (zh) * 1998-12-22 2007-11-07 微科学有限公司 基因和蛋白质,及它们的用途
US6890539B2 (en) * 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
CA2354843A1 (en) * 1998-12-22 2000-06-29 Microscience Limited Outer surface proteins, their genes, and their use
US6605709B1 (en) * 1999-04-09 2003-08-12 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics

Also Published As

Publication number Publication date
KR20010099885A (ko) 2001-11-09
CA2354843A1 (en) 2000-06-29
CN101486756A (zh) 2009-07-22
US20080226641A1 (en) 2008-09-18
HK1039339A1 (en) 2002-04-19
KR20060096515A (ko) 2006-09-11
AU758722B2 (en) 2003-03-27
EP1140994A1 (de) 2001-10-10
DK1140994T3 (da) 2005-08-15
EA200100701A1 (ru) 2001-12-24
JP2002533065A (ja) 2002-10-08
OA12425A (en) 2006-04-18
HUP0201022A2 (en) 2002-08-28
BR9916473A (pt) 2002-01-15
PT1140994E (pt) 2005-11-30
KR100866170B1 (ko) 2008-10-30
NZ542777A (en) 2007-11-30
NZ552871A (en) 2008-11-28
DE69925866D1 (de) 2005-07-21
KR20070027665A (ko) 2007-03-09
HUP0201022A3 (en) 2004-07-28
AP2006003504A0 (en) 2006-02-28
US20060104990A1 (en) 2006-05-18
NZ525538A (en) 2004-10-29
CZ20012174A3 (cs) 2002-02-13
EA009885B1 (ru) 2008-04-28
SI1140994T1 (sl) 2005-12-31
EP1140994B1 (de) 2005-06-15
US7217415B1 (en) 2007-05-15
AU1877900A (en) 2000-07-12
CN1733800A (zh) 2006-02-15
DE69925866T2 (de) 2005-11-24
PL351027A1 (en) 2003-02-24
KR20080052527A (ko) 2008-06-11
CN1357045A (zh) 2002-07-03
NO20013101L (no) 2001-08-13
NZ512296A (en) 2003-08-29
EP1574579A3 (de) 2006-02-22
ES2241352T3 (es) 2005-10-16
EP1574579A2 (de) 2005-09-14
KR100818815B1 (ko) 2008-04-01
NO20013101D0 (no) 2001-06-21
WO2000037490A3 (en) 2001-09-20
WO2000037490A2 (en) 2000-06-29

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