ATE299369T1 - Verwendungen von zusammensetzungen zur behandlung oder vermeidung von schlafstörungen mit sehr niedrigdosierten cyclobenzaprine - Google Patents
Verwendungen von zusammensetzungen zur behandlung oder vermeidung von schlafstörungen mit sehr niedrigdosierten cyclobenzaprineInfo
- Publication number
- ATE299369T1 ATE299369T1 AT00953996T AT00953996T ATE299369T1 AT E299369 T1 ATE299369 T1 AT E299369T1 AT 00953996 T AT00953996 T AT 00953996T AT 00953996 T AT00953996 T AT 00953996T AT E299369 T1 ATE299369 T1 AT E299369T1
- Authority
- AT
- Austria
- Prior art keywords
- cyclobenzaprine
- compositions
- treating
- sleep disorders
- low doses
- Prior art date
Links
- JURKNVYFZMSNLP-UHFFFAOYSA-N cyclobenzaprine Chemical compound C1=CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 JURKNVYFZMSNLP-UHFFFAOYSA-N 0.000 title 1
- 229960003572 cyclobenzaprine Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 208000019116 sleep disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14888199P | 1999-08-13 | 1999-08-13 | |
| PCT/US2000/022082 WO2001012175A1 (en) | 1999-08-13 | 2000-08-11 | Uses compositions for treating or preventing sleep disturbances using very low doses of cyclobenzaprine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE299369T1 true ATE299369T1 (de) | 2005-07-15 |
Family
ID=22527835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00953996T ATE299369T1 (de) | 1999-08-13 | 2000-08-11 | Verwendungen von zusammensetzungen zur behandlung oder vermeidung von schlafstörungen mit sehr niedrigdosierten cyclobenzaprine |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US6395788B1 (de) |
| EP (1) | EP1202722B1 (de) |
| JP (1) | JP2003506484A (de) |
| AR (1) | AR025110A1 (de) |
| AT (1) | ATE299369T1 (de) |
| AU (1) | AU6635400A (de) |
| BR (1) | BR0013017A (de) |
| CA (1) | CA2380432A1 (de) |
| DE (1) | DE60021266T2 (de) |
| ES (2) | ES2192156B1 (de) |
| GB (1) | GB2368522A (de) |
| HK (2) | HK1047883A1 (de) |
| IL (1) | IL147777A0 (de) |
| MX (1) | MXPA02001569A (de) |
| NZ (1) | NZ516749A (de) |
| PT (1) | PT1202722E (de) |
| WO (1) | WO2001012175A1 (de) |
| ZA (2) | ZA200200619B (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3422800A (en) * | 1999-02-18 | 2000-09-04 | Novartis Ag | Use of 5-ht3 receptor antagonists |
| US6635675B2 (en) | 2001-11-05 | 2003-10-21 | Cypress Bioscience, Inc. | Method of treating chronic fatigue syndrome |
| US6602911B2 (en) * | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
| GB0128674D0 (en) * | 2001-11-30 | 2002-01-23 | Boots Co Plc | Treatment of sleep disorders and the like |
| GB0312425D0 (en) * | 2003-05-30 | 2003-07-09 | Boots Co Plc | Use of a compound in the treatment of sleep disorders and the like,in providing refreshedness on waking and a method for the treatment of grogginess therewith |
| JP4578083B2 (ja) * | 2003-09-30 | 2010-11-10 | 小林製薬株式会社 | 催眠剤組成物 |
| US7994220B2 (en) * | 2005-09-28 | 2011-08-09 | Cypress Bioscience, Inc. | Milnacipran for the long-term treatment of fibromyalgia syndrome |
| US20070087055A1 (en) * | 2005-10-14 | 2007-04-19 | David Jan | Directly compressible extended release alprazolam formulation |
| PT1954669E (pt) * | 2005-12-01 | 2015-10-23 | Auspex Pharmaceuticals Inc | Feniletilaminas substituídas com actividade serotoninérgica e/ou norepinefrinérgica |
| WO2007098200A2 (en) * | 2006-02-16 | 2007-08-30 | Imthera Medical, Inc. | An rfid-based apparatus, system, and method for therapeutic treatment of obstructive sleep apnea |
| US20100179215A1 (en) * | 2006-05-19 | 2010-07-15 | Somaxon Pharmaceuticals, Inc. | Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders |
| US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
| SI2125698T1 (sl) | 2007-03-15 | 2016-12-30 | Auspex Pharmaceuticals, Inc. | Devterirani d9-venlafaksin |
| EP2197536A1 (de) | 2007-10-09 | 2010-06-23 | Imthera Medical, Inc. | System und verfahren zur neuralen stimulierung |
| CA2730190A1 (en) * | 2008-07-14 | 2010-01-21 | Queen's University At Kingston | Pharmaceutical compositions comprising ret inhibitors and methods for the treatment of cancer |
| BRPI0920548B8 (pt) | 2008-10-09 | 2021-06-22 | Imthera Medical Inc | aparelho para controlar posição da língua de um paciente |
| US9498440B2 (en) | 2009-05-22 | 2016-11-22 | Inventia Healthcare Private Limited | Extended release pharmaceutical compositions |
| JP2013509943A (ja) * | 2009-11-10 | 2013-03-21 | イムセラ・メディカル・インコーポレーテッド | 舌下神経を刺激して患者の舌の位置を調節するシステム |
| SMT201700578T1 (it) | 2009-11-20 | 2018-01-11 | Tonix Pharma Holdings Ltd | Metodo e composizioni per trattare i sintomi associati al disturbo da stress post-traumatico usando ciclobenzaprina |
| US20110319389A1 (en) | 2010-06-24 | 2011-12-29 | Tonix Pharmaceuticals, Inc. | Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine |
| US11998516B2 (en) * | 2011-03-07 | 2024-06-04 | Tonix Pharma Holdings Limited | Methods and compositions for treating depression using cyclobenzaprine |
| ITMI20110558A1 (it) * | 2011-04-06 | 2012-10-07 | Campiglio Consulting Srl | Composizione farmaceutica contenente ciclobenzaprina adatta alla somministrazione endonasale |
| WO2013168004A2 (en) * | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of fibromyalgia pain |
| RS63822B1 (sr) | 2012-06-15 | 2023-01-31 | Tonix Pharma Holdings Ltd | Kompozicije i postupci za transmukoznu apsorpciju |
| SMT202400324T1 (it) | 2013-03-15 | 2024-11-15 | Tonix Pharma Ltd | Formulazioni eutettiche di ciclobenzaprina cloridrato e mannitolo |
| MY186047A (en) | 2014-09-18 | 2021-06-17 | Tonix Pharma Holdings Ltd | Eutectic formulations of cyclobenzaprine hydrochloride |
| WO2019014651A1 (en) | 2017-07-13 | 2019-01-17 | Tonix Pharmaceuticals Holding Corp. | ANALOGUES OF CYCLOBENZAPRINE AND AMITRYPTILENE |
| MX2020006140A (es) * | 2017-12-11 | 2020-08-13 | Tonix Pharma Holdings Ltd | Tratamiento con ciclobenzaprina para la agitacion, psicosis y deterioro cognitivo en la demencia y enfermedades neurodegenerativas. |
| US20190381056A1 (en) | 2018-06-17 | 2019-12-19 | Axsome Therapeutics, Inc. | Compositions for delivery of reboxetine |
| US20220117915A1 (en) * | 2018-08-20 | 2022-04-21 | Tonix Pharma Holdings Limited | Methods of treating acute stress disorder and posttraumatic stress disorder |
| US20200147093A1 (en) | 2018-10-15 | 2020-05-14 | Axsome Therapeutics, Inc. | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
| US11020402B2 (en) | 2018-10-15 | 2021-06-01 | Axsome Therapeutics, Inc. | Use of reboxetine to treat narcolepsy |
| AU2021253592A1 (en) * | 2020-04-08 | 2022-11-10 | Tonix Pharmaceuticals Holding Corp. | Cyclobenzaprine treatment for sexual dysfunction |
| MX2023005899A (es) | 2020-11-20 | 2023-08-16 | TONIX Pharmaceuticals Holding Corp | Tratamiento con ciclobenzaprina para el trastorno por consumo de alcohol. |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
| US12565478B1 (en) | 2025-01-21 | 2026-03-03 | Axsome Therapeutics, Inc. | (S)-2-((S)-(2-ethoxyphenoxy)(phenyl)methyl)-4-nitrosomorpholine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1339636A (en) * | 1917-02-23 | 1920-05-11 | Tulloch Thomas Gregorie | Fluid-tight joint for steam-pipes and the like |
| GB859187A (en) | 1958-11-25 | 1961-01-18 | United States Borax Chem | Method for preparing substituted tris amino boranes |
| CA958643A (en) | 1970-07-07 | 1974-12-03 | Frosst (Charles E.) And Co. | Pharmaceutical compositions containing cyclobenzaprine |
| FR2121529A1 (en) * | 1971-01-05 | 1972-08-25 | Merck & Co Inc | Compsns contg cyclobenzaprine and indomethacin - chlordiazepoxide, phenylbutazone oxyphenbutazone or corticosteroid |
| AR025111A1 (es) * | 1999-08-13 | 2002-11-06 | Janus Pharmaceuticals Inc | Metodos y composiciones para tratar trastornos de ansiedad generalizada |
-
2000
- 2000-08-11 BR BR0013017-6A patent/BR0013017A/pt not_active Application Discontinuation
- 2000-08-11 JP JP2001516521A patent/JP2003506484A/ja active Pending
- 2000-08-11 DE DE60021266T patent/DE60021266T2/de not_active Expired - Lifetime
- 2000-08-11 CA CA002380432A patent/CA2380432A1/en not_active Abandoned
- 2000-08-11 GB GB0202908A patent/GB2368522A/en not_active Withdrawn
- 2000-08-11 US US09/637,557 patent/US6395788B1/en not_active Expired - Lifetime
- 2000-08-11 PT PT00953996T patent/PT1202722E/pt unknown
- 2000-08-11 HK HK02107660.2A patent/HK1047883A1/zh unknown
- 2000-08-11 AR ARP000104189A patent/AR025110A1/es unknown
- 2000-08-11 AT AT00953996T patent/ATE299369T1/de active
- 2000-08-11 ES ES200250016A patent/ES2192156B1/es not_active Withdrawn - After Issue
- 2000-08-11 HK HK02107664.8A patent/HK1047691B/en not_active IP Right Cessation
- 2000-08-11 NZ NZ516749A patent/NZ516749A/en not_active IP Right Cessation
- 2000-08-11 MX MXPA02001569A patent/MXPA02001569A/es unknown
- 2000-08-11 ES ES00953996T patent/ES2245944T3/es not_active Expired - Lifetime
- 2000-08-11 EP EP00953996A patent/EP1202722B1/de not_active Expired - Lifetime
- 2000-08-11 AU AU66354/00A patent/AU6635400A/en not_active Abandoned
- 2000-08-11 WO PCT/US2000/022082 patent/WO2001012175A1/en not_active Ceased
- 2000-08-11 IL IL14777700A patent/IL147777A0/xx unknown
-
2001
- 2001-06-27 US US09/893,758 patent/US6541523B2/en not_active Expired - Lifetime
-
2002
- 2002-01-23 ZA ZA200200619A patent/ZA200200619B/xx unknown
- 2002-01-30 ZA ZA200200852A patent/ZA200200852B/en unknown
-
2003
- 2003-03-17 US US10/392,366 patent/US20040029869A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60021266T2 (de) | 2006-05-24 |
| AU6635400A (en) | 2001-03-13 |
| BR0013017A (pt) | 2002-04-16 |
| EP1202722A1 (de) | 2002-05-08 |
| GB2368522A8 (en) | 2002-06-13 |
| GB0202908D0 (en) | 2002-03-27 |
| IL147777A0 (en) | 2002-08-14 |
| NZ516749A (en) | 2004-03-26 |
| US20010046988A1 (en) | 2001-11-29 |
| US6541523B2 (en) | 2003-04-01 |
| JP2003506484A (ja) | 2003-02-18 |
| ES2192156A1 (es) | 2003-09-16 |
| GB2368522A (en) | 2002-05-08 |
| ES2245944T3 (es) | 2006-02-01 |
| EP1202722B1 (de) | 2005-07-13 |
| ES2192156B1 (es) | 2005-02-16 |
| PT1202722E (pt) | 2005-11-30 |
| WO2001012175A1 (en) | 2001-02-22 |
| HK1047691B (en) | 2006-05-12 |
| WO2001012175A8 (en) | 2001-05-10 |
| DE60021266D1 (de) | 2005-08-18 |
| HK1047691A1 (en) | 2003-03-07 |
| ZA200200619B (en) | 2003-04-23 |
| US20040029869A1 (en) | 2004-02-12 |
| HK1047883A1 (zh) | 2003-03-14 |
| AR025110A1 (es) | 2002-11-06 |
| MXPA02001569A (es) | 2002-07-02 |
| CA2380432A1 (en) | 2001-02-22 |
| US6395788B1 (en) | 2002-05-28 |
| ZA200200852B (en) | 2003-07-30 |
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