ATE301833T1 - Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz - Google Patents
Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanzInfo
- Publication number
- ATE301833T1 ATE301833T1 AT99913652T AT99913652T ATE301833T1 AT E301833 T1 ATE301833 T1 AT E301833T1 AT 99913652 T AT99913652 T AT 99913652T AT 99913652 T AT99913652 T AT 99913652T AT E301833 T1 ATE301833 T1 AT E301833T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor protein
- protein molecules
- oligomerization
- screening
- peptide fragments
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 5
- 238000006384 oligomerization reaction Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000012216 screening Methods 0.000 title abstract 3
- 230000001737 promoting effect Effects 0.000 title 1
- 108010033276 Peptide Fragments Proteins 0.000 abstract 5
- 102000007079 Peptide Fragments Human genes 0.000 abstract 5
- 102000005962 receptors Human genes 0.000 abstract 5
- 108020003175 receptors Proteins 0.000 abstract 5
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/746—Erythropoetin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/505—Erythropoietin [EPO]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10232598 | 1998-04-14 | ||
| PCT/JP1999/001965 WO1999053313A1 (en) | 1998-04-14 | 1999-04-13 | Method for screening substance promoting oligomerization of receptor protein molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE301833T1 true ATE301833T1 (de) | 2005-08-15 |
Family
ID=14324407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99913652T ATE301833T1 (de) | 1998-04-14 | 1999-04-13 | Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070238128A9 (de) |
| EP (1) | EP1079230B1 (de) |
| JP (1) | JP4397122B2 (de) |
| AT (1) | ATE301833T1 (de) |
| AU (1) | AU3169599A (de) |
| DE (1) | DE69926624T2 (de) |
| ES (1) | ES2247790T3 (de) |
| WO (1) | WO1999053313A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0007217D0 (en) * | 2000-03-24 | 2000-05-17 | Europ I Of Oncology | Materials and methods relating to the treatment of leukaemias |
| EP1469309A4 (de) * | 2001-12-27 | 2007-11-21 | Japan Science & Tech Agency | Verfahren zur beurteilung der zellaktivität |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6247555A (ja) * | 1985-08-23 | 1987-03-02 | エフ.ホフマン ― ラ ロシュ アーゲー | シンチレ−シヨン近接定量法 |
| US5506107A (en) * | 1991-05-10 | 1996-04-09 | Genentech, Inc. | Selecting ligand agonists and antagonists |
| DE4228839A1 (de) * | 1992-08-29 | 1994-03-03 | Behringwerke Ag | Verfahren zum Nachweis und zur Bestimmung von Mediatoren |
-
1999
- 1999-04-13 JP JP2000543826A patent/JP4397122B2/ja not_active Expired - Fee Related
- 1999-04-13 AU AU31695/99A patent/AU3169599A/en not_active Abandoned
- 1999-04-13 EP EP99913652A patent/EP1079230B1/de not_active Expired - Lifetime
- 1999-04-13 DE DE69926624T patent/DE69926624T2/de not_active Expired - Lifetime
- 1999-04-13 WO PCT/JP1999/001965 patent/WO1999053313A1/ja not_active Ceased
- 1999-04-13 ES ES99913652T patent/ES2247790T3/es not_active Expired - Lifetime
- 1999-04-13 AT AT99913652T patent/ATE301833T1/de not_active IP Right Cessation
-
2004
- 2004-12-07 US US10/903,068 patent/US20070238128A9/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4397122B2 (ja) | 2010-01-13 |
| US20060183153A1 (en) | 2006-08-17 |
| US20070238128A9 (en) | 2007-10-11 |
| EP1079230A4 (de) | 2001-12-12 |
| ES2247790T3 (es) | 2006-03-01 |
| WO1999053313A1 (en) | 1999-10-21 |
| DE69926624D1 (de) | 2005-09-15 |
| EP1079230B1 (de) | 2005-08-10 |
| AU3169599A (en) | 1999-11-01 |
| DE69926624T2 (de) | 2006-05-18 |
| EP1079230A1 (de) | 2001-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |