ATE302026T1 - Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonie - Google Patents
Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonieInfo
- Publication number
- ATE302026T1 ATE302026T1 AT01903871T AT01903871T ATE302026T1 AT E302026 T1 ATE302026 T1 AT E302026T1 AT 01903871 T AT01903871 T AT 01903871T AT 01903871 T AT01903871 T AT 01903871T AT E302026 T1 ATE302026 T1 AT E302026T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- inhibitor
- heterometric
- proteins
- combination
- Prior art date
Links
- 229940030600 antihypertensive agent Drugs 0.000 title abstract 2
- 239000002220 antihypertensive agent Substances 0.000 title abstract 2
- 208000037849 arterial hypertension Diseases 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000019491 signal transduction Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 108091006027 G proteins Proteins 0.000 abstract 1
- 102000030782 GTP binding Human genes 0.000 abstract 1
- 108091000058 GTP-Binding Proteins 0.000 abstract 1
- 229940121649 protein inhibitor Drugs 0.000 abstract 1
- 239000012268 protein inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0000105A FR2803525B1 (fr) | 2000-01-06 | 2000-01-06 | Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle |
| PCT/FR2001/000027 WO2001049322A1 (fr) | 2000-01-06 | 2001-01-05 | Produit comprenant un inhibiteur de la transduction des signaux des proteines g heterotrimeriques en association avec un agent anti-hypertenseur pour une utilisation therapeutique dans le traitement de l'hypertension arterielle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE302026T1 true ATE302026T1 (de) | 2005-09-15 |
Family
ID=8845646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01903871T ATE302026T1 (de) | 2000-01-06 | 2001-01-05 | Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonie |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6846822B2 (de) |
| EP (1) | EP1248651B1 (de) |
| JP (1) | JP2003520787A (de) |
| AT (1) | ATE302026T1 (de) |
| AU (1) | AU3183801A (de) |
| CA (1) | CA2395955A1 (de) |
| DE (1) | DE60112719T2 (de) |
| DK (1) | DK1248651T3 (de) |
| ES (1) | ES2247060T3 (de) |
| FR (1) | FR2803525B1 (de) |
| WO (1) | WO2001049322A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2803525B1 (fr) * | 2000-01-06 | 2002-05-03 | Sod Conseils Rech Applic | Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle |
| JP4880591B2 (ja) | 2004-06-04 | 2012-02-22 | テバ ファーマシューティカル インダストリーズ リミティド | イルベサルタンを含む医薬組成物 |
| FR2879460B1 (fr) * | 2004-12-17 | 2007-02-23 | Sod Conseils Rech Applic | Associations anti-douleur comprenant un derive de dihydroimidazopyrazine |
| US7709468B2 (en) | 2005-09-02 | 2010-05-04 | Abbott Laboratories | Imidazo based heterocycles |
| TWI421252B (zh) | 2009-07-09 | 2014-01-01 | Irm Llc | 用於治療寄生蟲疾病之化合物及組合物 |
| FR3002453B1 (fr) * | 2013-02-28 | 2015-08-07 | Univ Bordeaux Segalen | Nouvelles combinaisons comprenant un extrait polyphenolique de marc de raisin avec un antihypertenseur et leurs utilisations |
| CN110691597A (zh) | 2017-04-24 | 2020-01-14 | 诺华股份有限公司 | 2-氨基-1-(2-(4-氟苯基)-3-(4-氟苯基氨基)-8,8-二甲基-5,6-二氢咪唑并[1,2-a]吡嗪-7(8H)-基)乙酮及其组合的治疗方案 |
| CN112480122B (zh) * | 2020-11-24 | 2022-03-22 | 中山大学 | 一种四氢咪唑[1,2-a]吡嗪类化合物、组合物及其制备方法与应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6673927B2 (en) * | 1996-02-16 | 2004-01-06 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Farnesyl transferase inhibitors |
| DE19637518A1 (de) * | 1996-09-13 | 1998-04-09 | Winfried Siffert | PTX-sensitive G-Proteine, ihre Herstellung und Verwendung |
| GT199800126A (es) * | 1997-08-29 | 2000-01-29 | Terapia de combinacion. | |
| FR2803525B1 (fr) * | 2000-01-06 | 2002-05-03 | Sod Conseils Rech Applic | Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle |
-
2000
- 2000-01-06 FR FR0000105A patent/FR2803525B1/fr not_active Expired - Fee Related
-
2001
- 2001-01-05 EP EP01903871A patent/EP1248651B1/de not_active Expired - Lifetime
- 2001-01-05 ES ES01903871T patent/ES2247060T3/es not_active Expired - Lifetime
- 2001-01-05 JP JP2001549688A patent/JP2003520787A/ja active Pending
- 2001-01-05 US US10/169,656 patent/US6846822B2/en not_active Expired - Fee Related
- 2001-01-05 AT AT01903871T patent/ATE302026T1/de active
- 2001-01-05 DK DK01903871T patent/DK1248651T3/da active
- 2001-01-05 DE DE60112719T patent/DE60112719T2/de not_active Expired - Lifetime
- 2001-01-05 WO PCT/FR2001/000027 patent/WO2001049322A1/fr not_active Ceased
- 2001-01-05 CA CA002395955A patent/CA2395955A1/fr not_active Abandoned
- 2001-01-05 AU AU31838/01A patent/AU3183801A/en not_active Abandoned
-
2004
- 2004-12-13 US US11/010,727 patent/US7132553B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030004168A1 (en) | 2003-01-02 |
| EP1248651B1 (de) | 2005-08-17 |
| US7132553B2 (en) | 2006-11-07 |
| CA2395955A1 (fr) | 2001-07-12 |
| EP1248651A1 (de) | 2002-10-16 |
| WO2001049322A1 (fr) | 2001-07-12 |
| FR2803525B1 (fr) | 2002-05-03 |
| US20050171113A1 (en) | 2005-08-04 |
| ES2247060T3 (es) | 2006-03-01 |
| DK1248651T3 (da) | 2006-01-02 |
| JP2003520787A (ja) | 2003-07-08 |
| DE60112719T2 (de) | 2006-06-08 |
| US6846822B2 (en) | 2005-01-25 |
| FR2803525A1 (fr) | 2001-07-13 |
| AU3183801A (en) | 2001-07-16 |
| DE60112719D1 (de) | 2005-09-22 |
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| Date | Code | Title | Description |
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