DK1248651T3 - Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertension - Google Patents

Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertension

Info

Publication number
DK1248651T3
DK1248651T3 DK01903871T DK01903871T DK1248651T3 DK 1248651 T3 DK1248651 T3 DK 1248651T3 DK 01903871 T DK01903871 T DK 01903871T DK 01903871 T DK01903871 T DK 01903871T DK 1248651 T3 DK1248651 T3 DK 1248651T3
Authority
DK
Denmark
Prior art keywords
treatment
heterotrimer
product
arterial hypertension
signal transduction
Prior art date
Application number
DK01903871T
Other languages
English (en)
Inventor
Gregoire Prevost
Marc Teillot
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of DK1248651T3 publication Critical patent/DK1248651T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK01903871T 2000-01-06 2001-01-05 Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertension DK1248651T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0000105A FR2803525B1 (fr) 2000-01-06 2000-01-06 Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle

Publications (1)

Publication Number Publication Date
DK1248651T3 true DK1248651T3 (da) 2006-01-02

Family

ID=8845646

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01903871T DK1248651T3 (da) 2000-01-06 2001-01-05 Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertension

Country Status (11)

Country Link
US (2) US6846822B2 (da)
EP (1) EP1248651B1 (da)
JP (1) JP2003520787A (da)
AT (1) ATE302026T1 (da)
AU (1) AU3183801A (da)
CA (1) CA2395955A1 (da)
DE (1) DE60112719T2 (da)
DK (1) DK1248651T3 (da)
ES (1) ES2247060T3 (da)
FR (1) FR2803525B1 (da)
WO (1) WO2001049322A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2803525B1 (fr) * 2000-01-06 2002-05-03 Sod Conseils Rech Applic Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle
DE602005025755D1 (de) 2004-06-04 2011-02-17 Teva Pharma Irbesartan enthaltende pharmazeutische zusammensetzung
FR2879460B1 (fr) * 2004-12-17 2007-02-23 Sod Conseils Rech Applic Associations anti-douleur comprenant un derive de dihydroimidazopyrazine
JP2009507032A (ja) 2005-09-02 2009-02-19 アボット・ラボラトリーズ 新規なイミダゾ系複素環
AR077463A1 (es) 2009-07-09 2011-08-31 Irm Llc Derivados de imidazo[1, 2 - a]pirazina y su uso en medicamentos para el tratamiento de enfermedades parasitarias
FR3002453B1 (fr) * 2013-02-28 2015-08-07 Univ Bordeaux Segalen Nouvelles combinaisons comprenant un extrait polyphenolique de marc de raisin avec un antihypertenseur et leurs utilisations
CN110691597A (zh) 2017-04-24 2020-01-14 诺华股份有限公司 2-氨基-1-(2-(4-氟苯基)-3-(4-氟苯基氨基)-8,8-二甲基-5,6-二氢咪唑并[1,2-a]吡嗪-7(8H)-基)乙酮及其组合的治疗方案
CN112480122B (zh) * 2020-11-24 2022-03-22 中山大学 一种四氢咪唑[1,2-a]吡嗪类化合物、组合物及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673927B2 (en) * 1996-02-16 2004-01-06 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Farnesyl transferase inhibitors
DE19637518A1 (de) * 1996-09-13 1998-04-09 Winfried Siffert PTX-sensitive G-Proteine, ihre Herstellung und Verwendung
GT199800126A (es) * 1997-08-29 2000-01-29 Terapia de combinacion.
FR2803525B1 (fr) * 2000-01-06 2002-05-03 Sod Conseils Rech Applic Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle

Also Published As

Publication number Publication date
ATE302026T1 (de) 2005-09-15
US20030004168A1 (en) 2003-01-02
DE60112719T2 (de) 2006-06-08
US20050171113A1 (en) 2005-08-04
JP2003520787A (ja) 2003-07-08
ES2247060T3 (es) 2006-03-01
US6846822B2 (en) 2005-01-25
AU3183801A (en) 2001-07-16
DE60112719D1 (de) 2005-09-22
CA2395955A1 (fr) 2001-07-12
EP1248651B1 (fr) 2005-08-17
FR2803525A1 (fr) 2001-07-13
FR2803525B1 (fr) 2002-05-03
WO2001049322A1 (fr) 2001-07-12
EP1248651A1 (fr) 2002-10-16
US7132553B2 (en) 2006-11-07

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