ATE302263T1 - Anlage zum brechen von zellen - Google Patents

Anlage zum brechen von zellen

Info

Publication number
ATE302263T1
ATE302263T1 AT00937895T AT00937895T ATE302263T1 AT E302263 T1 ATE302263 T1 AT E302263T1 AT 00937895 T AT00937895 T AT 00937895T AT 00937895 T AT00937895 T AT 00937895T AT E302263 T1 ATE302263 T1 AT E302263T1
Authority
AT
Austria
Prior art keywords
sample
cartridge
cells
plant
analyte
Prior art date
Application number
AT00937895T
Other languages
English (en)
Inventor
Michael T Taylor
Phillip Belgrader
Frazad Pourahmadi
William A Mcmillan
Ronald Chang
Stanley H Sakai
Jesus Ching
Kurt E Petersen
M Allen Northrup
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Application granted granted Critical
Publication of ATE302263T1 publication Critical patent/ATE302263T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C12N1/066—Lysis of microorganisms by physical processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809—Multifield plates or multicontainer arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/877—With flow control means for branched passages
    • Y10T137/87708—With common valve operator
    • Y10T137/87716—For valve having a flexible diaphragm valving member
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87917—Flow path with serial valves and/or closures
    • Y10T137/88046—Biased valve with external operator
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AT00937895T 1999-05-28 2000-05-30 Anlage zum brechen von zellen ATE302263T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13670399P 1999-05-28 1999-05-28
PCT/US2000/014740 WO2000073413A2 (en) 1999-05-28 2000-05-30 Apparatus and method for cell disruption

Publications (1)

Publication Number Publication Date
ATE302263T1 true ATE302263T1 (de) 2005-09-15

Family

ID=22473993

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00937895T ATE302263T1 (de) 1999-05-28 2000-05-30 Anlage zum brechen von zellen
AT00936386T ATE278771T1 (de) 1999-05-28 2000-05-30 Vorrichtung und verfahren zur analyse flüssiger proben

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT00936386T ATE278771T1 (de) 1999-05-28 2000-05-30 Vorrichtung und verfahren zur analyse flüssiger proben

Country Status (8)

Country Link
US (7) US6391541B1 (de)
EP (2) EP1208189B1 (de)
JP (2) JP4078073B2 (de)
AT (2) ATE302263T1 (de)
AU (2) AU782343B2 (de)
CA (2) CA2373249C (de)
DE (2) DE60014676T2 (de)
WO (2) WO2000073413A2 (de)

Families Citing this family (566)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
WO1998038487A2 (en) 1997-02-28 1998-09-03 Cepheid Heat exchanging, optically interrogated chemical reaction assembly
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6958392B2 (en) * 1998-10-09 2005-10-25 Whatman, Inc. Methods for the isolation of nucleic acids and for quantitative DNA extraction and detection for leukocyte evaluation in blood products
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US20040200909A1 (en) * 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US6391541B1 (en) * 1999-05-28 2002-05-21 Kurt E. Petersen Apparatus for analyzing a fluid sample
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
US6818185B1 (en) * 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US9073053B2 (en) 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
US6706519B1 (en) * 1999-06-22 2004-03-16 Tecan Trading Ag Devices and methods for the performance of miniaturized in vitro amplification assays
US6664104B2 (en) * 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
EP1080785A1 (de) * 1999-09-04 2001-03-07 F. Hoffmann-La Roche Ag Thermozyklisches System für Fluide in Patronen
US8518328B2 (en) * 2005-12-27 2013-08-27 Honeywell International Inc. Fluid sensing and control in a fluidic analyzer
JP3638503B2 (ja) * 2000-06-12 2005-04-13 アークレイ株式会社 カートリッジ式容器を用いる測定装置および測定方法並びに記録媒体
AU2001272876A1 (en) * 2000-07-21 2002-02-05 Point Of Care Ab A micro-calorimeter apparatus
US7255833B2 (en) * 2000-07-25 2007-08-14 Cepheid Apparatus and reaction vessel for controlling the temperature of a sample
FR2812303B1 (fr) * 2000-07-27 2002-12-06 Biomerieux Sa Procede de lyse cellulaire de procaryotes ou d'eucaryotes ou de lyse cellulaire simultanee de procaryotes et d'eucaryotes
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
DE10057832C1 (de) 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
AUPR298901A0 (en) 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
AU2002259017B2 (en) * 2001-04-26 2007-08-16 Boston Biomedica, Inc. Multichamber device and uses thereof for processing of biological samples
GB0110476D0 (en) * 2001-04-30 2001-06-20 Secr Defence Reagent delivery system
US8337419B2 (en) * 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
ATE485766T1 (de) 2001-06-12 2010-11-15 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
JP4209767B2 (ja) 2001-06-12 2009-01-14 ペリカン テクノロジーズ インコーポレイテッド 皮膚の性状の一時的変化に対する適応手段を備えた自動最適化形切開器具
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
EP1404232B1 (de) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Gerät und verfahren zur entnahme von blutproben
AU2002354838B2 (en) * 2001-07-19 2007-11-29 Infectio Diagnostic (I.D.I.) Inc. Universal method and composition for the rapid lysis of cells for the release of nucleic acids and their detection
EP1436405A4 (de) * 2001-08-20 2006-01-04 Whatman Inc Reinigung und gewinnung von dna aus hochpartikulären und feststoffproben
US6739531B2 (en) * 2001-10-04 2004-05-25 Cepheid Apparatus and method for rapid disruption of cells or viruses
DE10153925B4 (de) * 2001-11-02 2005-08-11 Unlimited Pharmaceutical Deutschland Gmbh Testgerät zum Nachweis von pharmakologisch wirksamen Verbindungen aus Speichel
WO2003065355A2 (en) * 2002-01-31 2003-08-07 Burstein Technologies, Inc. Bio-safety features for optical analysis disc and disc system including same
USD475795S1 (en) 2002-04-15 2003-06-10 Michael K. Johnson Liquid flow bubble release device
US8579831B2 (en) * 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7291117B2 (en) * 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) * 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) * 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7229458B2 (en) * 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) * 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7718072B2 (en) * 2002-04-26 2010-05-18 Abbott Laboratories Structure and method for handling magnetic particles in biological assays
US7220573B2 (en) * 2002-06-21 2007-05-22 Agilent Technologies, Inc. Array assay devices and methods of using the same
DE10228917A1 (de) * 2002-06-24 2004-01-22 Epigenomics Ag Vorrichtung zur Handhabung von Flüssigkeiten in einer Mehrzahl von Kanälen
MXPA05000816A (es) 2002-07-19 2005-04-28 Baxter Int Sistemas y metodos para realizar dialisis peritoneal.
US7745203B2 (en) * 2002-07-31 2010-06-29 Kabushiki Kaisha Toshiba Base sequence detection apparatus and base sequence automatic analyzing apparatus
US20040038385A1 (en) * 2002-08-26 2004-02-26 Langlois Richard G. System for autonomous monitoring of bioagents
US20120296233A9 (en) * 2002-09-05 2012-11-22 Freeman Dominique M Methods and apparatus for an analyte detecting device
AU2003303941A1 (en) * 2002-09-07 2004-10-11 Arizona Board Of Regents Integrated apparatus and methods for treating liquids
AU2003277069A1 (en) * 2002-09-30 2004-04-23 Ciphergen Biosystems, Inc. Apparatus and method for expression and capture of biomolecules and complexes on adsorbent surfaces
US7419797B2 (en) 2002-10-17 2008-09-02 Conestoga - Rovers And Associates Limited Rapid coliform detection system
US7932098B2 (en) * 2002-10-31 2011-04-26 Hewlett-Packard Development Company, L.P. Microfluidic system utilizing thin-film layers to route fluid
US20040086872A1 (en) * 2002-10-31 2004-05-06 Childers Winthrop D. Microfluidic system for analysis of nucleic acids
GB2395196B (en) * 2002-11-14 2006-12-27 Univ Cardiff Microfluidic device and methods for construction and application
GB0227765D0 (en) * 2002-11-28 2003-01-08 Secr Defence Apparatus for processing a fluid sample
EP1568766B1 (de) * 2002-11-28 2012-05-23 Arkray Inc. Vorrichtung zur vorbehandlung von proben
US6929945B2 (en) * 2002-12-09 2005-08-16 Advanced Fluidix Laboratories Llc Male fertility assay method and device
EP1583950B1 (de) * 2002-12-26 2017-04-05 Meso Scale Technologies, LLC. Testkassetten und verfahren zu ihrer verwendung
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2004083806A2 (en) 2003-01-22 2004-09-30 University Of South Florida Autonomous genosensor apparatus and methods for use
US20040228766A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
EP2238892A3 (de) * 2003-05-30 2011-02-09 Pelikan Technologies Inc. Vorrichtung zur Entnahme von Körperflüssigkeit
ES2490740T3 (es) 2003-06-06 2014-09-04 Sanofi-Aventis Deutschland Gmbh Aparato para toma de muestras de fluido sanguíneo y detección de analitos
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7604592B2 (en) * 2003-06-13 2009-10-20 Pelikan Technologies, Inc. Method and apparatus for a point of care device
WO2004113871A2 (en) * 2003-06-19 2004-12-29 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7341652B2 (en) * 2003-06-20 2008-03-11 Groton Biosytems, Llc Stationary capillary electrophoresis system
US7601545B2 (en) * 2003-06-20 2009-10-13 Groton Biosystems, Llc Automated macromolecule sample preparation system
US20040259076A1 (en) * 2003-06-23 2004-12-23 Accella Scientific, Inc. Nano and micro-technology virus detection method and device
WO2005011830A2 (en) * 2003-07-25 2005-02-10 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
EP1654066B1 (de) 2003-07-31 2014-11-12 Handylab, Inc. Verarbeitung von teilchenhaltigen proben
US20050054114A1 (en) * 2003-09-09 2005-03-10 Bayer Corporation Fluidics circuit of hematology analyzer with heated reaction chamber
US7541166B2 (en) * 2003-09-19 2009-06-02 Microfluidic Systems, Inc. Sonication to selectively lyse different cell types
WO2005028635A2 (en) * 2003-09-19 2005-03-31 Microfluidic Systems Inc. Microfluidic differential extraction cartridge
JP4522800B2 (ja) * 2003-09-19 2010-08-11 富士フイルム株式会社 抽出装置
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US7032605B1 (en) 2003-10-15 2006-04-25 Douglas B. Dority Dual piston rotary valve
CN1875260A (zh) * 2003-10-30 2006-12-06 拜尔健康护理有限责任公司 用于光学分析的结构和制造该结构的方法
WO2005043134A1 (en) 2003-10-30 2005-05-12 Bayer Healthcare Llc Optical cuvette with platform-and-well construction
WO2005055804A2 (en) 2003-12-02 2005-06-23 Musc Foundation For Research Development Methods and compositions for diagnosing epithelial cell cancer
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US20080312555A1 (en) * 2004-02-06 2008-12-18 Dirk Boecker Devices and methods for glucose measurement using rechargeable battery energy sources
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US7981616B2 (en) 2004-02-27 2011-07-19 Musc Foundation For Research Development Enhanced detection of RNA using a panel of truncated gene-specific primers for reverse transcription
DE102004017178A1 (de) * 2004-04-07 2005-11-03 Siemens Ag Vorrichtung und Verfahren zum Betätigen eines Ventils in einem mikromechanischen Gerät
WO2005100539A2 (en) 2004-04-07 2005-10-27 Levine, Robert, A. Disposable chamber for analyzing biologic fluids
US20050244837A1 (en) * 2004-04-28 2005-11-03 Cepheid Method and device for sample preparation control
DE102004021822B3 (de) * 2004-04-30 2005-11-17 Siemens Ag Verfahren und Anordnung zur DNA-Amplifikation mittels PCR unter Einsatz von Trockenreagenzien
DE102004021780B4 (de) * 2004-04-30 2008-10-02 Siemens Ag Verfahren und Anordnung zur DNA-Isolierung mit Trockenreagenzien
EP2345739B8 (de) 2004-05-03 2016-12-07 Handylab, Inc. Mikrofluidische Vorrichtung zur Verarbeitung polynukleotidhaltiger Proben
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
DE102005052713A1 (de) 2005-11-04 2007-05-16 Clondiag Chip Tech Gmbh Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1611954A1 (de) * 2004-07-03 2006-01-04 Roche Diagnostics GmbH Verbindungsstück zwischen Flüssigkeitsbehältern
AU2005271961B8 (en) 2004-07-09 2011-11-24 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Identification of markers in esophageal cancer, colon cancer, head and neck cancer and melanoma
US7611840B2 (en) * 2004-08-03 2009-11-03 Agency For Science, Technology And Research Method and device for the treatment of biological samples
WO2006029387A1 (en) * 2004-09-09 2006-03-16 Microfluidic Systems Inc. A handheld and portable microfluidic device to automatically prepare nucleic acids for analysis
WO2006039293A2 (en) * 2004-09-29 2006-04-13 University Of Virginia Patent Foundation Localized control of thermal properties on microdevices and applications thereof
WO2006044458A2 (en) 2004-10-13 2006-04-27 University Of Virginia Patent Foundation Electrostatic actuation for management of flow
US20080305538A1 (en) * 2004-10-19 2008-12-11 Medical Innovations International, Inc. Rapid and Sensitive Detection of Bacteria in Blood Products, Urine, and Other Fluids
EP1650297B1 (de) 2004-10-19 2011-04-13 Samsung Electronics Co., Ltd. Verfahren und Apparatur zur schnellen Zerstörung von Zellen und Viren durch die Verwendung von mikro magnet Kügelchen und Laser
KR100601972B1 (ko) * 2004-11-03 2006-07-18 삼성전자주식회사 레이저와 비드를 이용한 상 분리에 의한 핵산의 정제 장치및 방법
KR100601974B1 (ko) * 2004-11-25 2006-07-18 삼성전자주식회사 비드의 상이한 레이저 흡수에 의한 핵산의 정제 장치 및방법
CN100388967C (zh) * 2004-12-02 2008-05-21 鸿富锦精密工业（深圳）有限公司 颗粒分散方法及其设备
US7785868B2 (en) * 2004-12-02 2010-08-31 Microfluidic Systems, Inc. Apparatus to automatically lyse a sample
JP4922185B2 (ja) * 2004-12-22 2012-04-25 ユニバーシティ・オブ・ヴァージニア・パテント・ファウンデーション マイクロデバイスまたはナノスケールデバイスにおける熱用途または非熱用途のためのマイクロ波の使用
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
EP1852703A4 (de) * 2005-01-07 2010-02-17 Sekisui Chemical Co Ltd Nachweisvorrichtung mit kassette
KR100601983B1 (ko) * 2005-01-20 2006-07-18 삼성전자주식회사 시료 내 핵산 증폭 저해 물질의 제거 방법
EP1841854A4 (de) * 2005-01-27 2009-10-21 Applera Corp Vorrichtungen und verfahren zur probenherstellung
US20060203236A1 (en) * 2005-03-08 2006-09-14 Zhenghua Ji Sample cell
JP4656992B2 (ja) * 2005-04-14 2011-03-23 積水化学工業株式会社 マイクロフィルターユニット
US20060257907A1 (en) * 2005-04-19 2006-11-16 The Regents Of The University Of California Packed bed for nucleic acid capture and amplification
US20070014695A1 (en) * 2005-04-26 2007-01-18 Applera Corporation Systems and Methods for Multiple Analyte Detection
MX2007013985A (es) 2005-05-09 2008-02-22 Theranos Inc Sistemas de fluidos de punto de cuidado y usos de los mismos.
CA2607661C (en) 2005-05-09 2017-08-08 Idaho Technology, Inc. A device and method for two-stage nucleic acid amplification
US10816563B2 (en) 2005-05-25 2020-10-27 Boehringer Ingelheim Vetmedica Gmbh System for operating a system for the integrated and automated analysis of DNA or protein
CN101218032A (zh) 2005-05-25 2008-07-09 西门子公司 综合和自动化的dna或蛋白质分析系统及其运行方法
EP1910824A4 (de) 2005-05-31 2012-11-21 Labnow Inc Verfahren und zusammensetzungen in zusammenhang mit der erstellung und verwendung eines weissen blutbildes
US20060275852A1 (en) * 2005-06-06 2006-12-07 Montagu Jean I Assays based on liquid flow over arrays
US20100291588A1 (en) * 2005-06-24 2010-11-18 The Board Of Regents Of The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
US20070125942A1 (en) * 2005-07-06 2007-06-07 The Regents Of The University Of California Apparatuses, systems and methods for isolating and separating biological materials
ITBO20050481A1 (it) 2005-07-19 2007-01-20 Silicon Biosystems S R L Metodo ed apparato per la manipolazione e/o l'individuazione di particelle
US8343755B2 (en) 2005-08-01 2013-01-01 University Of Virginia Patent Foundation Microdevices for chemical sensing and chemical actuation
TW200712495A (en) * 2005-08-02 2007-04-01 3M Innovative Properties Co Apparatus and method for detecting an analyte
TW200714898A (en) * 2005-08-02 2007-04-16 3M Innovative Properties Co Apparatus and method for detecting an analyte
TW200712487A (en) * 2005-08-02 2007-04-01 3M Innovative Properties Co Apparatus and method for detecting an analyte
TW200712489A (en) * 2005-08-02 2007-04-01 3M Innovative Properties Co Apparatus assembly and method for detecting an analyte
US8220493B2 (en) * 2005-08-23 2012-07-17 University Of Virginia Patent Foundation Passive components for micro-fluidic flow profile shaping and related method thereof
EP1928603A1 (de) * 2005-09-02 2008-06-11 California Institute Of Technology Verfahren und vorrichtung zur mechanischen auslösung von ventilen in fluidischen vorrichtungen
KR100700093B1 (ko) * 2005-09-23 2007-03-28 삼성전자주식회사 레이저 및 자성 비드를 이용한 세포 또는 바이러스 파괴장치
CA2624243C (en) 2005-09-29 2013-12-31 Siemens Medical Solutions Usa, Inc. Microfluidic chip for synthesizing radioactively labeled molecules suitable for human imaging with positron emission tomography
CA2624914A1 (en) * 2005-10-04 2007-04-12 University Of Virginia Patent Foundation Microchip-based acoustic trapping or capture of cells for forensic analysis and related method thereof
JP2009511059A (ja) * 2005-10-11 2009-03-19 ハンディーラブ インコーポレイテッド ポリヌクレオチドサンプル調製装置
WO2007047336A2 (en) * 2005-10-12 2007-04-26 University Of Virginia Patent Foundation Integrated microfluidic analysis systems
US7731901B2 (en) * 2005-10-19 2010-06-08 Abbott Laboratories Apparatus and method for performing counts within a biologic fluid sample
ITBO20050646A1 (it) 2005-10-26 2007-04-27 Silicon Biosystem S R L Metodo ed apparato per la caratterizzazione ed il conteggio di particelle
WO2007055165A1 (ja) * 2005-11-11 2007-05-18 Konica Minolta Medical & Graphic, Inc. 核酸の分離方法、核酸検査用マイクロリアクタ、核酸検査システム
US20070141605A1 (en) * 2005-11-21 2007-06-21 Applera Corporation Portable preparation, analysis, and detection apparatus for nucleic acid processing
US8182767B2 (en) * 2005-12-27 2012-05-22 Honeywell International Inc. Needle-septum interface for a fluidic analyzer
US7485153B2 (en) * 2005-12-27 2009-02-03 Honeywell International Inc. Fluid free interface for a fluidic analyzer
EP1981636A4 (de) * 2006-02-03 2010-06-09 California Inst Of Techn Mikrofluidisches verfahren und struktur mit gasdurchlässiger elastomerdichtung
JP5063616B2 (ja) 2006-02-03 2012-10-31 インテジェニックス インコーポレイテッド マイクロ流体デバイス
US7862000B2 (en) 2006-02-03 2011-01-04 California Institute Of Technology Microfluidic method and structure with an elastomeric gas-permeable gasket
DE202006020469U1 (de) 2006-03-06 2008-10-16 Directif Gmbh Vorrichtung zum Nachweis biochemischer Zielmoleküle
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US9040288B2 (en) 2006-03-24 2015-05-26 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using the same
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
EP1997888A4 (de) * 2006-03-24 2010-07-28 Toshiba Kk Nukleinsäuredetektionskassette und nukleinsäuredetektionsvorrichtung
US7507583B2 (en) * 2006-03-27 2009-03-24 Savannah River Nuclear Solutions, Llc Analysis of large soil samples for actinides
ITTO20060226A1 (it) 2006-03-27 2007-09-28 Silicon Biosystem S P A Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche
EP2021128A2 (de) * 2006-05-01 2009-02-11 Koninklijke Philips Electronics N.V. Flüssigkeitsprobentransportvorrichtung mit verringertem totvolumen zur verarbeitung, kontrolle und/oder für den nachweis einer flüssigkeitsprobe
US8900828B2 (en) * 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
US20100216657A1 (en) * 2006-05-16 2010-08-26 Arcxis Biotechnologies, Inc. Pcr-free sample preparation and detection systems for high speed biologic analysis and identification
USD559996S1 (en) * 2006-05-26 2008-01-15 Fujifilm Corporation Component extractor for extracting nucleic acids
US8119352B2 (en) 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
US7549349B2 (en) * 2006-06-22 2009-06-23 Evogen, Inc. Sample cartridge for air-sampling device
US20080000892A1 (en) * 2006-06-26 2008-01-03 Applera Corporation Heated cover methods and technology
US7629124B2 (en) 2006-06-30 2009-12-08 Canon U.S. Life Sciences, Inc. Real-time PCR in micro-channels
WO2008012550A2 (en) * 2006-07-28 2008-01-31 Diagnostics For The Real World, Ltd. Device, system and method for processing a sample
US7633606B2 (en) * 2006-08-24 2009-12-15 Microfluidic Systems, Inc. Integrated airborne substance collection and detection system
US7858366B2 (en) * 2006-08-24 2010-12-28 Microfluidic Systems, Inc Integrated airborne substance collection and detection system
US7705739B2 (en) * 2006-08-24 2010-04-27 Microfluidic Systems, Inc. Integrated airborne substance collection and detection system
US20070080613A1 (en) * 2006-09-20 2007-04-12 Sterlite Optical Technologies Ltd Storage and transportation device for storing and transporting optical fiber preform and precursors thereof
US20080069732A1 (en) * 2006-09-20 2008-03-20 Robert Yi Diagnostic test system
WO2008039875A1 (en) * 2006-09-28 2008-04-03 California Institute Of Technology System and method for interfacing with a microfluidic chip
EP2082197A1 (de) * 2006-10-06 2009-07-29 Respiratorius AB Einrichtung zur medikamentenuntersuchung
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US9102911B2 (en) 2009-05-15 2015-08-11 Biofire Diagnostics, Llc High density self-contained biological analysis
US20080124777A1 (en) * 2006-11-29 2008-05-29 Canon U.S. Life Sciences, Inc. Method for releasing genetic material from solid phase
US20080121591A1 (en) * 2006-11-29 2008-05-29 Canon U.S. Life Sciences, Inc. Device for nucleic acid preparation
US20080131954A1 (en) * 2006-11-30 2008-06-05 Canon U.S. Life Sciences, Inc. Method of Separating Target DNA from Mixed DNA
WO2008075501A1 (ja) 2006-12-19 2008-06-26 Konica Minolta Medical & Graphic, Inc. 回転式抽出容器、それを用いた細胞種の同定方法、遺伝子検出方法、及び自動核酸抽出装置
US8338166B2 (en) * 2007-01-04 2012-12-25 Lawrence Livermore National Security, Llc Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
US7829032B2 (en) 2007-01-23 2010-11-09 Siemens Medical Solutions Usa, Inc. Fully-automated microfluidic system for the synthesis of radiolabeled biomarkers for positron emission tomography
US7830560B2 (en) 2007-01-31 2010-11-09 Hewlett-Packard Development Company, L.P. System and method for adaptive digital ramp current control
US20090011417A1 (en) * 2007-03-07 2009-01-08 George Maltezos Testing Device
US8153064B2 (en) 2007-03-22 2012-04-10 Doebler Ii Robert W Systems and devices for isothermal biochemical reactions and/or analysis
EP2149610B1 (de) 2007-03-26 2018-05-16 Fundacion Gaiker Vorrichtung zum nachweis genetischen materials mittels polymerasekettenreaktion
EP3626345A1 (de) 2007-04-04 2020-03-25 ANDE Corporation Systeme zur schnellen multiplex-amplifikation von zielnukleinsäuren
US8071035B2 (en) 2007-04-12 2011-12-06 Siemens Medical Solutions Usa, Inc. Microfluidic radiosynthesis system for positron emission tomography biomarkers
FR2917095B1 (fr) * 2007-06-07 2009-07-17 Biomerieux Sa Dispositif de lyse de microorganismes presents dans un echantillon environnemental ou clinique et d'extraction des acides nucleiques desdits microorganismes aux fins d'analyse.
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
ES2648798T3 (es) 2007-07-13 2018-01-08 Handylab, Inc. Materiales de captura de polinucleótidos y métodos de utilización de los mismos
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
EP2610007B1 (de) 2007-07-23 2018-12-05 CLONDIAG GmbH Testverfahren
US20090030342A1 (en) * 2007-07-27 2009-01-29 3M Innovative Properties Company Apparatus and method for releasing a sample of material
GB0715170D0 (en) * 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Reaction vessel
GB0715171D0 (en) * 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Sample processor
US20110212491A1 (en) * 2007-08-03 2011-09-01 Enigma Diagnostics Limited Reaction vessel
WO2009024773A1 (en) 2007-08-17 2009-02-26 Diagnostics For The Real World, Ltd Device, system and method for processing a sample
WO2009026394A1 (en) * 2007-08-20 2009-02-26 Pelikan Technologies, Inc. Body fluid sampling systems
US8444587B2 (en) 2007-10-01 2013-05-21 Baxter International Inc. Fluid and air handling in blood and dialysis circuits
US7871462B2 (en) * 2007-10-01 2011-01-18 Baxter International Inc. Dialysis systems having air separation chambers with internal structures to enhance air removal
US7892332B2 (en) * 2007-10-01 2011-02-22 Baxter International Inc. Dialysis systems having air traps with internal structures to enhance air removal
US7892331B2 (en) 2007-10-01 2011-02-22 Baxter International Inc. Dialysis systems having air separation chambers with internal structures to enhance air removal
CN104297506B (zh) 2007-10-02 2017-05-03 赛拉诺斯股份有限公司 模块化现场护理装置及其应用
US20100236637A1 (en) * 2007-10-05 2010-09-23 Hendrix Jr James Edward Surface Ventilator For A Compliant-Surface Flow-Control Device
US8123947B2 (en) * 2007-10-22 2012-02-28 Baxter International Inc. Priming and air removal systems and methods for dialysis
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
ITTO20070771A1 (it) 2007-10-29 2009-04-30 Silicon Biosystems Spa Metodo e apparato per la identificazione e manipolazione di particelle
US8381169B2 (en) * 2007-10-30 2013-02-19 International Business Machines Corporation Extending unified process and method content to include dynamic and collaborative content
US9428746B2 (en) 2007-10-31 2016-08-30 Akonni Biosystems, Inc. Method and kit for purifying nucleic acids
US20090111193A1 (en) 2007-10-31 2009-04-30 Cooney Christopher G Sample preparation device
US7759112B2 (en) * 2007-10-31 2010-07-20 Akonni Biosystems, Inc. Apparatus, system, and method for purifying nucleic acids
US10125388B2 (en) 2007-10-31 2018-11-13 Akonni Biosystems, Inc. Integrated sample processing system
US20090137024A1 (en) * 2007-11-28 2009-05-28 Canon U.S. Life Sciences, Inc. Method of Separating Target DNA from Mixed DNA
EP2232245A1 (de) * 2007-12-06 2010-09-29 Agency for Science, Technology And Research Integrierte vorrichtung zur durchführung und überwachung chemischer reaktionen
WO2009089466A2 (en) 2008-01-09 2009-07-16 Keck Graduate Institute System, apparatus and method for material preparation and/or handling
GB0800798D0 (en) * 2008-01-17 2008-02-27 Secr Defence An acoustic device
WO2009105499A1 (en) * 2008-02-20 2009-08-27 Termaat Joel R Thermocycler and sample vessel for rapid amplification of dna
US8096786B2 (en) 2008-02-27 2012-01-17 University Of Massachusetts Three dimensional micro-fluidic pumps and valves
US8857279B2 (en) * 2008-03-03 2014-10-14 William P. Hanson Analyte screening and detection systems and methods
EP2263092A4 (de) * 2008-03-31 2014-01-22 Agency Science Tech & Res Fluidaufarbeitung und -transport unter verwendung einer zusammengeschalteten mehrkammervorrichtung
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
US8961902B2 (en) 2008-04-23 2015-02-24 Bioscale, Inc. Method and apparatus for analyte processing
DE102008021000A1 (de) 2008-04-25 2009-10-29 Qiagen Gmbh Verfahren und Vorrichtung zum Aufschluss von biologischem Material
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US8133451B2 (en) * 2008-08-28 2012-03-13 Microfluidic Systems, Inc. Sample preparation apparatus
JP2010099061A (ja) * 2008-09-26 2010-05-06 Sekisui Chem Co Ltd 検出用カートリッジ及び被検出物質の検出方法
US20100093098A1 (en) * 2008-10-14 2010-04-15 Siemens Medical Solutions Nonflow-through appratus and mehod using enhanced flow mechanisms
IT1391619B1 (it) 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
US10895575B2 (en) 2008-11-04 2021-01-19 Menarini Silicon Biosystems S.P.A. Method for identification, selection and analysis of tumour cells
FR2938062B1 (fr) * 2008-11-05 2014-02-28 Biomerieux Sa Dispositif de preparation et/ou de traitement d'un echantillon biologique
FR2938063B1 (fr) 2008-11-05 2014-09-19 Commissariat Energie Atomique Dispositif de preparation et/ou de traitement d'un echantillon biologique
FR2939445B1 (fr) 2008-12-10 2013-05-03 Biomerieux Sa Systeme automatise de lyse de microorganismes presents dans un echantillon, d'extraction et de purification des acides nucleiques desdits microorganismes aux fins d'analyse.
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
JP5782384B2 (ja) * 2009-02-03 2015-09-24 ネットバイオ・インコーポレーテッドＮｅｔＢｉｏ， Ｉｎｃ． 未処理試料から核酸を単離するための自己完結型装置および精製方法
AU2015215950B2 (en) * 2009-02-03 2017-06-29 Ande Corporation Nucleic Acid Purification
ITBO20090154A1 (it) * 2009-03-17 2010-09-18 Silicon Biosystems Spa Sistema microfluidico
US9192943B2 (en) * 2009-03-17 2015-11-24 Silicon Biosystems S.P.A. Microfluidic device for isolation of cells
WO2010120786A1 (en) * 2009-04-13 2010-10-21 Micronics, Inc. Microfluidic clinical analyzer
CA2752715C (en) 2009-04-14 2018-05-01 Arie R. Van Doorn Hifu induced cavitation with reduced power threshold
BRPI1012522B1 (pt) 2009-04-15 2019-11-26 Biocartis N V sistema ótico de multiplexação e método para detectar componentes de amostra em pelo menos duas câmaras de amostra diferentes
WO2010118542A1 (en) 2009-04-15 2010-10-21 Biocartis Sa Protection of bioanalytical sample chambers
EP2427270B1 (de) 2009-05-06 2015-04-01 Biocartis NV Vorrichtung zum schneiden eines probenträgers
WO2010132756A2 (en) * 2009-05-14 2010-11-18 Streck, Inc. Sample processing cassette, system, and method
US8282789B2 (en) * 2009-05-18 2012-10-09 Bing-Nan Lee Microwave apparatus and method of extracting essential oils, essence, and pigments with gas flow
US8282788B2 (en) * 2009-05-18 2012-10-09 Bing-Nan Lee Extraction apparatus and method of extracting essential oils, essence, and pigments from odorous raw material by microwave heating under sub-critical conditions
US20110130560A1 (en) * 2009-05-29 2011-06-02 Bio-Rad Laboratories, Inc. Sonication cartridge for nucleic acid extraction
RU2559541C2 (ru) 2009-06-05 2015-08-10 Интедженкс Инк. Универсальная система подготовки образцов и применение в интегрированной системе анализа
US9550985B2 (en) 2009-06-15 2017-01-24 Netbio, Inc. Methods for forensic DNA quantitation
CA2766517A1 (en) 2009-06-26 2010-12-29 Claremont Biosolutions Llc Capture and elution of bio-analytes via beads that are used to disrupt specimens
JP4911264B2 (ja) 2009-07-09 2012-04-04 凸版印刷株式会社 核酸抽出用キット、核酸抽出方法及び核酸抽出装置
AU2010308329B2 (en) 2009-10-19 2016-10-13 Labrador Diagnostics Llc Integrated health data capture and analysis system
US20110091873A1 (en) * 2009-10-21 2011-04-21 Microfluidic Systems, Inc. Integrated sample preparation and amplification for nucleic acid detection from biological samples
US9034280B2 (en) * 2009-12-16 2015-05-19 General Electric Corporation High-throughput methods and systems for processing biological materials
US9579651B2 (en) 2009-12-18 2017-02-28 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge
WO2011077333A1 (en) * 2009-12-23 2011-06-30 Koninklijke Philips Electronics N.V. Analyte measurement apparatus and method
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
CA2796586C (en) * 2010-02-23 2017-10-24 Genturadx-Usa, Inc. Apparatus and methods for integrated sample preparation, reaction and detection
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
FR2959312B1 (fr) 2010-04-23 2023-01-20 Biomerieux Sa Dispositif de preparation et/ou de traitement d'un echantillon biologique
WO2011151804A1 (en) 2010-06-03 2011-12-08 Spinomix S.A. A fluidic interfacing system and assembly
US20180071733A1 (en) * 2010-08-02 2018-03-15 Dxna Llc Pressurizable cartridge for polymerase chain reactions
EP2601286A4 (de) * 2010-08-02 2016-10-05 Brent L Weight Unter druck stehende kartusche für polymerase-kettenreaktionen
ITBO20100502A1 (it) * 2010-08-04 2012-02-05 Silicon Biosystems Spa Sistema microfluidico
ITBO20100504A1 (it) * 2010-08-04 2012-02-05 Silicon Biosystems Spa Sistema microfluidico
WO2012024658A2 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Integrated analysis system
JP5837742B2 (ja) * 2010-08-27 2015-12-24 学校法人東京女子医科大学 細胞単離装置
JP5909654B2 (ja) 2010-09-24 2016-04-27 パナソニックＩｐマネジメント株式会社 フィルターデバイス
KR101254675B1 (ko) * 2010-10-25 2013-04-15 주식회사 싸이토젠 세포 채집 장치
KR101420094B1 (ko) 2010-10-27 2014-07-17 (주)바이오니아 다양한 생체시료분석을 위한 전자동실시간정량증폭장비, 다양한 생체시료분석을 위한 자동정제 및 반응준비 장치, 전자동 핵산정제 및 실시간 정량 유전자증폭 방법, 전자동 핵산정제방법, 실시간정량ｐｃｒ을 이용한 병원균의 전자동 생균수검사방법, 정량면역ｐｃｒ을 이용한 전자동 항원농도획득방법 및 타겟항원에 라벨링된 부착용 타겟핵산의 정제방법
US8986986B2 (en) 2010-10-29 2015-03-24 Samsung Electronics Co., Ltd. Cell lysis device and methods of lysing cells or viruses
KR101776215B1 (ko) * 2010-10-29 2017-09-08 삼성전자 주식회사 세포 파쇄용 마이크로 디바이스 및 이를 이용한 세포 파쇄 방법
US8663974B2 (en) 2010-12-23 2014-03-04 Claremont Biosolutions Llc Compositions and methods for capture and elution of biological materials via particulates
US8382711B2 (en) 2010-12-29 2013-02-26 Baxter International Inc. Intravenous pumping air management systems and methods
ES2533839T3 (es) 2010-12-30 2015-04-15 Abbott Point Of Care, Inc. Cartucho de análisis de fluido biológico con porción de manipulación de muestra y porción de cámara de análisis
WO2012096480A2 (en) 2011-01-10 2012-07-19 Lg Electronics Inc. Diagnostic cartridge and control method for diagnostic cartridge
CN103477197B (zh) 2011-01-21 2016-08-17 提拉诺斯公司 样品使用最大化的系统和方法
CN106190806B (zh) 2011-04-15 2018-11-06 贝克顿·迪金森公司 扫描实时微流体热循环仪和用于同步的热循环和扫描光学检测的方法
NZ735051A (en) 2011-05-12 2022-11-25 Netbio Inc Methods and compositions for rapid multiplex amplification of str loci
CA2835654A1 (en) 2011-06-01 2012-12-06 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
EP2532433A1 (de) * 2011-06-06 2012-12-12 Koninklijke Philips Electronics N.V. Vorrichtung zum Fragmentieren von Molekülen einer Probe durch Ultraschall
WO2013013304A1 (en) 2011-07-25 2013-01-31 Qvella Corporation Methods and devices for electrical sample preparation
CN105817276B (zh) 2011-08-24 2018-02-06 艾博特健康公司 生物流体样品分析盒
US8988684B1 (en) 2011-09-08 2015-03-24 Lawrence Livermore National Security, Llc System and method for measuring fluorescence of a sample
US9372135B1 (en) 2011-09-08 2016-06-21 Lawrence Livermore National Security, Llc Fluidics platform and method for sample preparation
US8808643B1 (en) 2011-09-08 2014-08-19 Lawrence Livermore National Security, Llc Fluidics platform and method for sample preparation and analysis
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
DK2761305T3 (da) 2011-09-30 2017-11-20 Becton Dickinson Co Forenet reagensstrimmel
US20150136604A1 (en) 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
US10865440B2 (en) 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
ITTO20110990A1 (it) 2011-10-28 2013-04-29 Silicon Biosystems Spa Metodo ed apparato per l'analisi ottica di particelle a basse temperature
WO2013067202A1 (en) 2011-11-04 2013-05-10 Handylab, Inc. Polynucleotide sample preparation device
KR101481054B1 (ko) 2011-11-15 2015-01-14 한국기계연구원 핵산 자동 분석 장치
ITBO20110766A1 (it) 2011-12-28 2013-06-29 Silicon Biosystems Spa Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico
DK2810080T3 (da) 2012-02-03 2024-06-17 Becton Dickinson Co Eksterne filer til fordeling af molekylære diagnostiske tests og bestemmelse af kompatabilitet imellem tests
US9637775B2 (en) 2012-02-13 2017-05-02 Neumodx Molecular, Inc. System and method for processing biological samples
US9604213B2 (en) 2012-02-13 2017-03-28 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US11931740B2 (en) 2012-02-13 2024-03-19 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
EP2814942B1 (de) 2012-02-13 2024-07-03 Neumodx Molecular, Inc. Mikrofluidische kartusche zur verarbeitung und zum nachweis von nucleinsäuren
US11485968B2 (en) 2012-02-13 2022-11-01 Neumodx Molecular, Inc. Microfluidic cartridge for processing and detecting nucleic acids
WO2013133725A1 (en) * 2012-03-09 2013-09-12 Rawle Christopher Bruce Portable device for detecting molecule(s)
EP3381558A1 (de) 2012-03-16 2018-10-03 Stat-Diagnostica & Innovation, S.L. Verfahren für testkartusche mit integriertem übertragungsmodul
DE102012205171B3 (de) 2012-03-29 2013-09-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Integriertes Einweg-Chipkartuschensystem für mobile Multiparameteranalysen chemischer und/oder biologischer Substanzen
ITTO20120320A1 (it) * 2012-04-12 2013-10-13 St Microelectronics Srl Dispositivo e metodo per la preparazione di campioni biologici, in particolare per l'estrazione del dna, e il caricamento in pozzetti per la successiva esecuzione della pcr
SG194247A1 (en) * 2012-04-16 2013-11-29 Biofactory Pte Ltd Method and apparatus for cell disruption
EP2839028B1 (de) 2012-04-20 2016-12-28 Cepheid Verfahren zur erkennung von blasenkrebs
EP2841600B1 (de) 2012-04-27 2024-04-24 Cepheid Vorrichtung mit heterogenen verarbeitungsmodulen
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
AU2012381985A1 (en) * 2012-06-05 2015-01-29 Dairy Quality Inc. Biological fluid analysis system and method
US20150259671A1 (en) * 2012-07-31 2015-09-17 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
US9399986B2 (en) 2012-07-31 2016-07-26 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
US9932632B2 (en) 2012-08-10 2018-04-03 Streck, Inc. Real-time optical system for polymerase chain reaction
NL2017959B1 (en) * 2016-12-08 2018-06-19 Illumina Inc Cartridge assembly
EP2900836B1 (de) 2012-09-28 2023-05-10 Cepheid Pcr mit zwei primern für ein mikrorns-multiplex-assay
US9957553B2 (en) 2012-10-24 2018-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
DE102012219575A1 (de) * 2012-10-25 2014-04-30 Robert Bosch Gmbh Zum Lysieren einsetzbare Vorrichtungen, Verfahren und System
ES2741749T3 (es) 2012-10-25 2020-02-12 Neumodx Molecular Inc Método y materiales para el aislamiento de materiales de ácido nucleico
KR102134053B1 (ko) * 2012-11-16 2020-07-14 유니바사루 바이오 리사치 가부시키가이샤 직동형 반응 처리장치 및 그 방법
WO2014093360A1 (en) 2012-12-10 2014-06-19 Landers James P Frequency-based filtering of mechanical actuation using fluidic device
JP2016509206A (ja) 2012-12-21 2016-03-24 マイクロニクス， インコーポレイテッド 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ
US10518262B2 (en) 2012-12-21 2019-12-31 Perkinelmer Health Sciences, Inc. Low elasticity films for microfluidic use
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
CN110237880A (zh) 2013-01-18 2019-09-17 生米公司 分析设备
US9587236B2 (en) * 2013-01-18 2017-03-07 Folim G. Halaka Continuous sonication for biotechnology applications and biofuel production
WO2014112671A1 (ko) * 2013-01-21 2014-07-24 나노바이오시스(주) 핵산 추출용 미세유동 칩, 이를 포함하는 핵산 추출 장치, 및 이를 이용하는 핵산 추출 방법
WO2014138396A1 (en) 2013-03-06 2014-09-12 Cepheid Methods of detecting bladder cancer
AU2013205148B2 (en) * 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom
US9194848B2 (en) 2013-03-15 2015-11-24 Practichem, Llc Multi-measurement flow cell assembly for liquid chromatography
CN107866286A (zh) 2013-03-15 2018-04-03 金马克诊断股份有限公司 用于操纵可变形流体容器的系统、方法和设备
EP2972154A4 (de) * 2013-03-15 2016-11-16 Practichem Llc Mehrmessungsdurchflusszellenanordnung für die flüssigchromatografie
US9670479B2 (en) 2013-03-15 2017-06-06 F Cubed, LLC Sample preparation device and methods of use
CN104330549B (zh) * 2013-04-03 2017-01-25 艾博生物医药(杭州)有限公司 一种识别检测板的正反两面的装置及方法
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CN105189784B (zh) 2013-05-07 2020-06-30 珀金埃尔默健康科学有限公司 用于制备和分析核酸的装置
CA2911303C (en) 2013-05-07 2021-02-16 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
WO2014210593A1 (en) 2013-06-28 2014-12-31 Streck, Inc. Devices for real-time polymerase chain reaction
US9536304B2 (en) 2013-08-30 2017-01-03 Dairy Quality Inc. Determining pathogens based on an image of somatic cells in a fluid sample
US11504709B2 (en) * 2013-10-15 2022-11-22 Kianoosh Peyvan Capture, disruption, and extraction apparatus and method
US10436680B2 (en) * 2013-10-15 2019-10-08 Kianoosh Peyvan Capture, disruption, and extraction apparatus and method
US10294512B2 (en) 2013-10-21 2019-05-21 Sung-Chun Kim Method and apparatus for analyzing biomolecules by using oligonucleotide
CA2935138C (en) 2013-10-22 2021-04-20 Sung-Chun Kim Marker for generating binding information on biomolecules and nucleic acids, preparation method therefor, and method and apparatus for analyzing biomolecule by using same
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
CN105873681B (zh) 2013-11-18 2019-10-11 尹特根埃克斯有限公司 用于样本分析的卡盒和仪器
EP2878375A1 (de) 2013-11-29 2015-06-03 Genewave Mikrofluidische Kartusche für molekulare Diagnose, Andockstation mit solch einer mikrofluidischen Kartusche und Verfahren zur Analyse einer biologischen Probe
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
US10634590B2 (en) 2014-03-11 2020-04-28 Emd Millipore Corporation IHC, tissue slide fluid exchange disposable and system
CN104946510B (zh) * 2014-03-31 2017-06-06 博奥生物集团有限公司 集核酸扩增和微阵列检测于一体的微流控装置
DE102014105437A1 (de) 2014-04-16 2015-10-22 Amodia Bioservice Gmbh Mikrofluidik-Modul und Kassette für die immunologische und molekulare Diagnostik in einem Analyseautomaten
EP3134553B1 (de) 2014-04-24 2019-08-21 Lucira Health, Inc. Kolorimetrische detektion von nukleinsäureamplifikation
US10208332B2 (en) 2014-05-21 2019-02-19 Integenx Inc. Fluidic cartridge with valve mechanism
JP6960223B2 (ja) 2014-05-27 2021-11-05 イラミーナ インコーポレーテッド 基礎器具と取外可能カートリッジとを含む生化学的解析のためのシステム及び方法
WO2015187849A2 (en) 2014-06-04 2015-12-10 Lucigen Corporation Sample collection and analysis devices
AU2014403832B2 (en) 2014-08-22 2021-11-04 Cepheid Methods of detecting influenza
US20160067709A1 (en) * 2014-09-05 2016-03-10 Htc Corporation Micro-channel module
US9701933B2 (en) 2014-09-19 2017-07-11 Sarfaraz K. Niazi Harvesting and purification or perfusion yielder (HAPPY) device
JP6675168B2 (ja) * 2014-09-30 2020-04-01 キヤノンメディカルシステムズ株式会社 核酸検査装置
US9486590B2 (en) 2014-09-29 2016-11-08 Fenwal, Inc. Automatic purging of air from a fluid processing system
US11587686B2 (en) 2014-10-16 2023-02-21 Cepheid Biosecurity screening system and method
EP3209410B1 (de) 2014-10-22 2024-12-25 IntegenX Inc. Elektrophoretische kassette und entsprechendes verfahren zur automatisierten vorbereitung, verarbeitung und analyse von proben
WO2016069853A2 (en) 2014-10-30 2016-05-06 Cepheid Methods of detecting ebola
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
US9365044B1 (en) * 2014-12-12 2016-06-14 Funai Electric Co., Ltd. Printhead cartridge with hydrophobic coating
HK1247255A1 (zh) 2014-12-15 2018-09-21 Cepheid 底数大於2的指数核酸扩增
US9623415B2 (en) 2014-12-31 2017-04-18 Click Diagnostics, Inc. Devices and methods for molecular diagnostic testing
GB2530596B (en) 2015-02-02 2016-08-24 Atlas Genetics Ltd Improved blister assembly
GB201501705D0 (en) 2015-02-02 2015-03-18 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
GB2531615B (en) * 2015-02-02 2017-11-22 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
GB2531616B (en) 2015-02-02 2017-11-22 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
WO2016168747A1 (en) * 2015-04-16 2016-10-20 Terumo Bct, Inc. Automated protein production and cell lysing
WO2016205233A2 (en) 2015-06-15 2016-12-22 Cepheid Integrated purification and measurement of dna methylation and co-measurement of mutations and/or mrna expression levels in an automated reaction cartridge
US10233491B2 (en) 2015-06-19 2019-03-19 IntegenX, Inc. Valved cartridge and system
JP2018524718A (ja) 2015-06-25 2018-08-30 ガンブロ・ルンディア・エービーＧａｍｂｒｏ Ｌｕｎｄｉａ Ａｂ 分散データベースを有する医療装置システム及び方法
EP3325647B1 (de) 2015-07-24 2020-02-19 Cepheid Zusammensetzung und verfahren fur dna und rna extraierung vom gewebe proben
WO2017062991A1 (en) * 2015-10-09 2017-04-13 Silicon Biodevices, Inc. Industrial design of stand-alone assay system
WO2017116694A1 (en) * 2015-12-29 2017-07-06 3M Innovative Properties Company Method and system for detecting microorganisms in large-volume samples
US10625009B2 (en) 2016-02-17 2020-04-21 Baxter International Inc. Airtrap, system and method for removing microbubbles from a fluid stream
EP3429752A4 (de) 2016-03-14 2019-10-30 Lucira Health, Inc. Systeme und verfahren zur durchführung von biologischen tests
JP6891191B2 (ja) 2016-03-14 2021-06-18 ルシラ ヘルス インコーポレイテッド 光学的性質を改変するための装置および方法
DK3429543T3 (da) 2016-03-14 2025-01-27 Pfizer Selektivt ventilerede biologiske analyseanordninger og tilhørende fremgangsmåder
CN117269282A (zh) * 2016-03-31 2023-12-22 深圳市理邦精密仪器股份有限公司 测试卡组件及血气分析仪
CN106483180B (zh) * 2016-03-31 2024-08-23 深圳市理邦精密仪器股份有限公司 血气分析仪及其血气生化测试卡
WO2017197040A1 (en) * 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
US10774393B2 (en) 2016-05-20 2020-09-15 Roche Molecular Systems, Inc. Cell surface marker depletion in a sample processing device
DE102016209904A1 (de) * 2016-06-06 2017-12-07 Robert Bosch Gmbh Verfahren und mikrofluidische Vorrichtung zum Verarbeiten einer Probe biologischen Materials
EP3464596B1 (de) 2016-06-07 2025-07-30 Cepheid Thermostabile polymeraseinhibitorzusammensetzungen und verfahren
EP3478857A1 (de) 2016-06-29 2019-05-08 Click Diagnostics, Inc. Vorrichtungen und verfahren zur detektion von molekülen unter verwendung einer durchflusszelle
US10349589B2 (en) 2016-09-08 2019-07-16 Hemex Health, Inc. Diagnostics systems and methods
AU2017324053B2 (en) * 2016-09-08 2020-08-06 Hemex Health, Inc. Diagnostics systems and methods
SG10201913814QA (en) * 2016-09-12 2020-03-30 Delta Electronics Intl Singapore Pte Ltd Nucleic Acid Analysis Apparatus
US11376581B2 (en) 2016-09-12 2022-07-05 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
US11478791B2 (en) 2016-09-12 2022-10-25 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
US11426735B2 (en) 2016-09-12 2022-08-30 Delta Electronics Int'l (Singapore) Pte Ltd Nucleic acid analysis apparatus
US11249077B2 (en) 2016-09-30 2022-02-15 Arkray, Inc. Method for magnetically labeling particles and labeling apparatus
EP3523032A2 (de) * 2016-10-07 2019-08-14 Boehringer Ingelheim Vetmedica GmbH Kartusche zum testen einer probe
CN109803762B (zh) * 2016-10-07 2022-04-01 勃林格殷格翰维特梅迪卡有限公司 用于控制分析装置和分析系统的方法
CA3035141A1 (en) 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Method and analysis system for testing a sample
CA3037247A1 (en) 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Analysis device and method for testing a sample
US10422012B2 (en) 2016-10-10 2019-09-24 Roche Molecular Systems, Inc. Devices comprising bacteriophage PHI6 internal control compositions
CN111781139B (zh) 2016-10-14 2023-09-12 亿明达股份有限公司 夹盒组件
USD814652S1 (en) * 2016-10-14 2018-04-03 Spartan Bioscience In. Cartridge
US11231347B2 (en) 2016-11-29 2022-01-25 S2 Genomics, Inc. Method and apparatus for processing tissue samples
WO2018111935A1 (en) 2016-12-12 2018-06-21 Cepheid Integrated purification and measurement of dna methylation and co-measurement of mutations and/or mrna expression levels in an automated reaction cartridge
TWI611171B (zh) 2016-12-14 2018-01-11 財團法人工業技術研究院 生物樣品處理裝置
CN110100283B (zh) 2016-12-21 2023-07-04 甘布罗伦迪亚股份公司 包括具有支持外域的安全集群域的信息技术基础架构的医疗设备系统
US11080848B2 (en) 2017-04-06 2021-08-03 Lucira Health, Inc. Image-based disease diagnostics using a mobile device
JP2018174826A (ja) * 2017-04-14 2018-11-15 キヤノンメディカルシステムズ株式会社 核酸調製器具
US20190093155A1 (en) 2017-05-25 2019-03-28 Roche Molecular Systems, Inc. Multiplex Nucleic Acid Amplification Assay
US11602750B2 (en) 2017-05-30 2023-03-14 Roche Molecular Systems, Inc. Customizable sample processing device
JP2020525802A (ja) * 2017-06-26 2020-08-27 メンドーサ, エステバンMENDOZA, Estevan 試料濾過装置
JP7120802B2 (ja) * 2017-07-20 2022-08-17 株式会社神戸製鋼所 流体流通装置及びその流通異常検知方法
US20190134634A1 (en) 2017-08-09 2019-05-09 Shazi Iqbal Reagent Storage Device for Storing a Target-Specific Reagent
CN110892247B (zh) 2017-08-17 2023-08-25 雅培医护站股份有限公司 用于执行光学和电化学测定的设备、系统和方法
WO2019035082A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. TECHNIQUES FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS WITH UNIVERSAL CIRCUITS
CN110869745B (zh) 2017-08-17 2023-08-11 雅培医护站股份有限公司 用于执行光学测定的设备、系统和方法
JP7046166B2 (ja) 2017-09-14 2022-04-01 ルシラ ヘルス インコーポレイテッド 電子読み出しを用いる多重化バイオアッセイデバイス
JP7293236B2 (ja) 2017-09-15 2023-06-19 バイオミーム インコーポレイテッド 自動試料処理のための方法およびシステム
JP2019075997A (ja) * 2017-10-20 2019-05-23 花王株式会社 吸収性物品に移行した微生物から核酸又はタンパク質を抽出する方法
US11491487B2 (en) * 2017-10-23 2022-11-08 Cytochip Inc. Devices and methods for measuring analytes and target particles
AU2018359609B2 (en) 2017-10-31 2023-01-05 F. Hoffmann-La Roche Ag Improved magnetic particles and uses thereof
MX2020004783A (es) 2017-11-09 2020-08-13 Visby Medical Inc Dispositivo portatil para el diagnostico molecular y metodos para la deteccion de virus objetivo.
CN111712581A (zh) * 2017-12-15 2020-09-25 生米公司 用于分析样品的便携式装置和方法
WO2019121850A1 (en) 2017-12-19 2019-06-27 F. Hoffmann-La Roche Ag Method of making a frangible seal in a sample processing device
KR102065649B1 (ko) * 2017-12-28 2020-01-13 에스디 바이오센서 주식회사 핵산 추출용 카트리지의 피스톤
KR102065650B1 (ko) * 2017-12-28 2020-02-11 에스디 바이오센서 주식회사 카트리지를 이용한 핵산 추출 방법
EP3735281B1 (de) 2018-01-05 2024-11-27 Path Ex, Inc. Vorrichtung zur erfassung und entfernung von krankheitsmaterial aus fluiden
US11147897B2 (en) * 2018-04-06 2021-10-19 American Sterilizer Company Sterilization process challenge device
WO2019200166A1 (en) * 2018-04-11 2019-10-17 The Trustees Of Indiana University Cartridges, systems and methods for mass spectrometry
CN108753569A (zh) * 2018-05-25 2018-11-06 苏州博福生物医药科技有限公司 一种用于捕获细胞或生物分子的富集筛选机构
US11618876B2 (en) 2018-06-01 2023-04-04 S2 Genomics, Inc. Method and apparatus for processing tissue samples
DE102018210069A1 (de) * 2018-06-21 2019-12-24 Robert Bosch Gmbh Mikrofluidische Vorrichtung, Verfahren zu deren Herstellung und Verwendung
EP3586963A1 (de) * 2018-06-29 2020-01-01 PreOmics GmbH Mittel und verfahren zur lysierung biologischer zellen
US10974240B2 (en) * 2018-07-06 2021-04-13 Qorvo Us, Inc. Fluidic channel for a cartridge
CN112423883A (zh) * 2018-07-12 2021-02-26 卢米耐克斯公司 用于进行可变样品制备和分析过程的系统和方法
JP2021534804A (ja) 2018-09-03 2021-12-16 ビスビュー メディカル，インコーポレイテッド 抗生物質感受性検査のための装置および方法
CA3109452A1 (en) 2018-10-01 2020-04-09 Boehringer Ingelheim Vetmedica Gmbh Peristaltic pump and analyzer for testing a sample
EP3874064A1 (de) 2018-10-29 2021-09-08 Cepheid Exponentielle base-3-nukleinsäureamplifikation mit reduzierter amplifikationszeit unter verwendung verschachtelter überlappender primer
EP3807007A4 (de) * 2018-11-30 2022-05-04 Illumina Inc Systeme und verfahren zur aktiven erwärmung einer kartusche
WO2020112678A2 (en) 2018-11-30 2020-06-04 Illumina, Inc. Temperature-controllable reagent cartridge and temperature control system for the same
USD920534S1 (en) 2018-12-21 2021-05-25 CanaryQ, Inc. Blood sample filtration device
USD907232S1 (en) 2018-12-21 2021-01-05 Lucira Health, Inc. Medical testing device
US12478291B2 (en) 2019-01-29 2025-11-25 Instrumentation Laboratory Company Hematocrit level detection using IR laser refraction
AU2020232685B2 (en) * 2019-03-05 2024-12-19 Pfizer Inc. Bubble-free liquid filling of fluidic chambers
EP3942281A4 (de) 2019-03-21 2022-11-16 Biomeme, Inc. Multifunktionale analytische vorrichtungen
US11918996B2 (en) * 2019-04-15 2024-03-05 Genecapture, Inc. Integrated cartridge for sample homogenization and nucleic acid fragmentation
US12263478B2 (en) 2019-04-28 2025-04-01 Visby Medical, Inc. Molecular diagnostic devices with digital detection capability and wireless connectivity
WO2020243741A1 (en) 2019-05-28 2020-12-03 Levine Robert A Apparatus and method for transferring and analyzing suspended particles in a liquid sample
WO2020264182A1 (en) 2019-06-25 2020-12-30 Hemex Health, Inc. Diagnostics systems and methods
US11053473B2 (en) * 2019-06-25 2021-07-06 Hemex Health, Inc. External sonication
WO2021011512A1 (en) 2019-07-15 2021-01-21 Lexagene, Inc. Sample preparation cartridges and apparatuses
US10820847B1 (en) 2019-08-15 2020-11-03 Talis Biomedical Corporation Diagnostic system
EP4061511A4 (de) * 2019-11-19 2023-09-27 University of Cincinnati Vorrichtungen und verfahren zur konzentration von analyten
CN112940061B (zh) 2019-12-10 2024-05-03 财团法人工业技术研究院 核酸萃取装置
US11254979B2 (en) 2020-06-01 2022-02-22 Shaheen Innovations Holding Limited Systems and devices for infectious disease screening
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
EP4085149A4 (de) 2020-01-03 2024-03-06 Visby Medical, Inc. Vorrichtungen und verfahren zur prüfung von antibiotischer suszeptibilität
US12687470B2 (en) 2020-04-06 2026-07-21 Shaheen Innovations Holding Limited Cell lysis systems and methods
USD953561S1 (en) 2020-05-05 2022-05-31 Lucira Health, Inc. Diagnostic device with LED display
EP3919176A1 (de) * 2020-06-01 2021-12-08 Shaheen Innovations Holding Limited Testvorrichtungen und systeme zum screening auf infektionskrankheiten
EP3919175A1 (de) * 2020-06-01 2021-12-08 Shaheen Innovations Holding Limited Systeme und vorrichtungen zur untersuchung infektiöser erkrankungen
IL298682B2 (en) * 2020-06-01 2026-02-01 Shaheen Innovations Holding Ltd Infectious disease scanning device
AU2021285405B2 (en) 2020-06-01 2026-06-18 Shaheen Innovations Holding Limited An infectious disease screening system
USD962470S1 (en) 2020-06-03 2022-08-30 Lucira Health, Inc. Assay device with LCD display
US12298233B2 (en) 2020-06-11 2025-05-13 Siemens Healthcare Diagnostics Inc. Method and analyzer to correct for unknown interferences in a patient blood sample
BR112022026414A2 (pt) 2020-06-26 2023-03-14 Cepheid Métodos para detectar sars-cov-2, influenza e rsv
AU2021312126B2 (en) 2020-07-23 2025-09-25 American Sterilizer Company Sterilization process challenge device
WO2022061105A1 (en) 2020-09-18 2022-03-24 Biomeme, Inc. Portable devices and methods for analyzing samples
BR112023006262A2 (pt) 2020-10-06 2023-05-09 Cepheid Métodos de diagnóstico de tuberculose e de diferenciação entre tuberculose ativa e latente
GB2622964B (en) * 2020-10-19 2024-12-04 Quantumdx Group Ltd Integrated thermal conditioning and PCR in a molecular POC diagnostic system
CN116648625A (zh) 2020-10-30 2023-08-25 塞弗德公司 具有可更换的处理模块和远程监测的诊断测定系统
DE102020134836B3 (de) 2020-12-23 2022-03-24 LCTech GmbH Extraktionssystem zur Extraktion von Analyten aus einer Probe
CN116963837A (zh) * 2020-12-24 2023-10-27 英维沃斯珂瑞股份有限公司 化学处理系统、仪器和样品盒
US20250144623A1 (en) * 2020-12-24 2025-05-08 Invivoscribe Inc. Chemical processing system, instrument and sample cartridge
CA3203372A1 (en) * 2020-12-24 2022-06-30 Jeffrey Edward MILLER Chemical processing system, instrument and sample cartridge
USD1134925S1 (en) 2021-12-21 2026-07-14 Invivoscribe, Inc. Fluid transfer apparatus
WO2022182837A1 (en) * 2021-02-26 2022-09-01 Collins James J Devices and methods for rapid nucleic acid preparation and detection
US20220298572A1 (en) 2021-03-16 2022-09-22 Cepheid Compositions and methods for discriminating bacterial and viral infections in a human subject
WO2022251508A1 (en) * 2021-05-28 2022-12-01 Proof Diagnostics Reaction cartridge
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
CN113308369B (zh) * 2021-07-14 2025-02-11 北京乐普智慧医疗科技有限公司 一种核酸检测卡盒及其组装工艺
WO2023055917A1 (en) * 2021-09-29 2023-04-06 Fremonta Corporation Methods and systems for sample processing utilizing filter aid materials and aggregating samplers for equipment
USD1017066S1 (en) 2021-10-01 2024-03-05 Becton, Dickinson And Company Microfluidic cartridge
EP4409032A4 (de) * 2021-10-01 2025-12-24 Becton Dickinson Co Einspurige verstärkungskartusche
JP2023063027A (ja) * 2021-10-22 2023-05-09 株式会社エンプラス 流体取扱装置およびこれを含む流体取扱システム
CN117106887A (zh) 2021-10-22 2023-11-24 塞弗德公司 诊断和治疗结核病的组合物和方法
US12618774B2 (en) 2022-04-15 2026-05-05 Instrumentation Laboratory Co. Fluid testing system
USD1014780S1 (en) 2022-04-15 2024-02-13 Instrumentation Laboratory Co. Cuvette
US12643104B2 (en) 2022-10-28 2026-06-02 Seegene, Inc. Cartridge for detecting target analyte
KR102921590B1 (ko) * 2022-10-28 2026-02-03 주식회사 씨젠 타깃 분석물 검출 카트리지
US20240139726A1 (en) * 2022-10-28 2024-05-02 Seegene, Inc. Cartridge for detecting target analyte
CN120641576A (zh) 2022-12-16 2025-09-12 塞弗德公司 Mpox演化支ii生物标志物组
DE202023002794U1 (de) 2022-12-27 2024-07-15 AVITA Medical Americas, LLC Kassette zur Herstellung einer regenerativen epidermalen Suspension
US12570949B2 (en) 2022-12-27 2026-03-10 AVITA Medical Americas, LLC Systems and devices for wound therapy and related methods of use
CN121001822A (zh) 2023-01-30 2025-11-21 塞弗德公司 呼吸道生物标志物组合
WO2025023652A1 (ko) * 2023-07-21 2025-01-30 주식회사 진시스템 Pcr 검사를 위한 핵산 추출용 양면칩, 이를 포함하는 카트리지, 및 이를 이용한 핵산추출장치
WO2025023649A1 (ko) * 2023-07-21 2025-01-30 주식회사 진시스템 Pcr 검사를 위한 핵산 추출용 양면칩, 이를 포함하는 카트리지, 및 이를 이용한 핵산추출장치
US20250171840A1 (en) 2023-09-18 2025-05-29 Cepheid Three-phase nested amplification and multi-phasic detection
US20250144626A1 (en) * 2023-11-03 2025-05-08 Seegene, Inc. Cartridge for detecting target analyte
USD1112812S1 (en) 2023-12-22 2026-02-10 AVITA Medical Americas, LLC Tissue processing cartridge
WO2025175133A1 (en) 2024-02-14 2025-08-21 Cepheid Melt shape genotyping
WO2025179142A1 (en) 2024-02-22 2025-08-28 Cepheid Maximizing optical channel capabilities for target detection
WO2026020144A1 (en) 2024-07-19 2026-01-22 Cepheid Liposomal controlled release of pcr reaction reagents
WO2026055639A1 (en) 2024-09-06 2026-03-12 Cepheid Sample in sequencing-ready library out automated library preparation solution
WO2026055452A1 (en) * 2024-09-09 2026-03-12 Abbott Point Of Care, Inc. Analysis cartridges and methods of using them
WO2026136820A1 (en) 2024-12-20 2026-06-25 Cepheid Dna polymerase inhibitor
WO2026146661A1 (ko) * 2024-12-30 2026-07-09 주식회사 진시스템 Pcr 검사를 위한 핵산 추출용 듀얼 양면칩
KR20260106721A (ko) * 2024-12-30 2026-07-07 주식회사 진시스템 핵산분주장치 및 핵산분주방법
WO2026146662A1 (ko) * 2024-12-30 2026-07-09 주식회사 진시스템 Pcr 검사를 위한 핵산 추출용 듀얼 양면칩을 구비하는 카트리지
WO2026160685A1 (ko) * 2025-01-22 2026-07-30 엘지전자 주식회사 바이오센서 카트리지
WO2026160684A1 (ko) * 2025-01-22 2026-07-30 엘지전자 주식회사 바이오센서 카트리지
WO2026160686A1 (ko) * 2025-01-22 2026-07-30 엘지전자 주식회사 바이오센서 카트리지

Family Cites Families (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US955351A (en) * 1909-05-13 1910-04-19 Palmer I E Co Resilient bottom for couch-hammocks, &c.
US2856148A (en) * 1952-02-08 1958-10-14 Vickers Electrical Co Ltd Valve assembly
GB938163A (en) * 1960-09-20 1963-10-02 Boots Pure Drug Co Ltd Improvements in or relating to particle size reduction or cellular disruption
US3448890A (en) 1966-05-02 1969-06-10 Lusteroid Container Co Inc Plastic tube construction
US3799742A (en) 1971-12-20 1974-03-26 C Coleman Miniaturized integrated analytical test container
US4180383A (en) 1975-04-07 1979-12-25 Becton, Dickinson And Company Chamber holder for immobilized immunoadsorbent
US4336719A (en) * 1980-07-11 1982-06-29 Panametrics, Inc. Ultrasonic flowmeters using waveguide antennas
US4426451A (en) 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
US4335719A (en) * 1981-02-04 1982-06-22 Johnston Samuel R Irrigation device
SE8102316L (sv) 1981-04-10 1982-10-11 Pharmacia Diagnostics Ab Anordning for genomforande av analyser
AU570439B2 (en) 1983-03-28 1988-03-17 Compression Labs, Inc. A combined intraframe and interframe transform coding system
US4615984A (en) 1984-02-23 1986-10-07 Becton Dickinson & Company Dissociation of ligand-binder complex using ultrasound
US4963498A (en) 1985-08-05 1990-10-16 Biotrack Capillary flow device
AU604684B2 (en) * 1986-03-20 1991-01-03 Gen-Probe Incorporated Method for releasing RNA and DNA from cells
GB2191110B (en) 1986-06-06 1989-12-06 Plessey Co Plc Chromatographic separation device
US4789628A (en) 1986-06-16 1988-12-06 Vxr, Inc. Devices for carrying out ligand/anti-ligand assays, methods of using such devices and diagnostic reagents and kits incorporating such devices
US4915812A (en) 1986-06-20 1990-04-10 Molecular Devices Corporation Zero volume cell
JPS63105977A (ja) 1986-10-22 1988-05-11 Ise Kagaku Kogyo Kk 薄膜を形成させる方法
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
CH667599A5 (fr) 1986-12-11 1988-10-31 Battelle Memorial Institute Enceinte destinee a contenir un milieu liquide.
US4918025A (en) 1987-03-03 1990-04-17 Pb Diagnostic Systems, Inc. Self contained immunoassay element
US4855240A (en) 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
DD284131A7 (de) 1987-07-10 1990-11-07 �����@�������`����k�� Verfahren und vorrichtung zur herstellung bioaktiver suspensionen
US4908318A (en) 1987-09-04 1990-03-13 Integrated Genetics, Inc. Nucleic acid extraction methods
US4846440A (en) * 1987-09-30 1989-07-11 Spectra Physics Valve with metal diaphragm and flat surface valve body
US4923978A (en) * 1987-12-28 1990-05-08 E. I. Du Pont De Nemours & Company Process for purifying nucleic acids
US4921952A (en) 1988-01-21 1990-05-01 The United States Of America As Represented By The United States Department Of Energy Nucleic acid isolation process
US4983523A (en) 1988-04-08 1991-01-08 Gene-Trak Systems Methods for preparing sample nucleic acids for hybridization
SE8801299L (sv) 1988-04-08 1989-10-09 Bertil Hoeoek Mikromekanisk envaegsventil
US5374533A (en) 1988-05-10 1994-12-20 Tetjin Limited Method for determining chondrocalcin
US4908112A (en) 1988-06-16 1990-03-13 E. I. Du Pont De Nemours & Co. Silicon semiconductor wafer for analyzing micronic biological samples
FR2634892B1 (fr) 1988-07-28 1990-09-14 Guigan Jean Dispositif pour la realisation d'analyses biologiques par detection immuno-enzymatique d'anticorps ou d'antigenes dans un serum
JP2671135B2 (ja) 1988-08-01 1997-10-29 東湘電機株式会社 細胞の超音波破砕装置
US5395502A (en) * 1988-11-14 1995-03-07 Anthony R. Torres Apparatus for performing and universally detecting capillary isoelectric focusing without mobilization using concentration gradient imaging systems
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
JPH02234600A (ja) * 1989-03-07 1990-09-17 Mitsubishi Mining & Cement Co Ltd 圧電変換素子
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5207988A (en) 1989-07-06 1993-05-04 The Cleveland Clinic Foundation Apparatus for detecting and quantifying clot lysis and establishing optimum medication and dosages
US5124444A (en) 1989-07-24 1992-06-23 Microprobe Corporation Lactam-containing compositions and methods useful for the extraction of nucleic acids
US5231015A (en) 1989-10-18 1993-07-27 Eastman Kodak Company Methods of extracting nucleic acids and pcr amplification without using a proteolytic enzyme
AU642444B2 (en) 1989-11-30 1993-10-21 Mochida Pharmaceutical Co., Ltd. Reaction vessel
US5858188A (en) 1990-02-28 1999-01-12 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
US5770029A (en) 1996-07-30 1998-06-23 Soane Biosciences Integrated electrophoretic microdevices
US5582829A (en) 1990-04-05 1996-12-10 Rx Technologies, Inc. Sonicated borrelia burgdorferi vaccine
US5143084A (en) 1990-05-24 1992-09-01 Spacelabs, Inc. Disposable cartridge for sampling and analyzing body fluids
US5114858A (en) 1990-06-26 1992-05-19 E. I. Du Pont De Nemours And Company Cellular component extraction process in a disposable filtration vessel
DE4126436A1 (de) 1990-09-17 1992-03-19 Abion Ohg Einwegreaktionsgefaess fuer die festphasenimmunanalytik und verfahren zur messung von ueber immunreaktionen bestimmbaren komponenten
US5652141A (en) * 1990-10-26 1997-07-29 Oiagen Gmbh Device and process for isolating nucleic acids from cell suspension
US5352777A (en) 1990-12-26 1994-10-04 Pioneer Hi-Bred International, Inc. DNA isolation from animal cells
SE9100392D0 (sv) 1991-02-08 1991-02-08 Pharmacia Biosensor Ab A method of producing a sealing means in a microfluidic structure and a microfluidic structure comprising such sealing means
US5264184A (en) 1991-03-19 1993-11-23 Minnesota Mining And Manufacturing Company Device and a method for separating liquid samples
US5422241A (en) 1991-07-03 1995-06-06 Ambion, Inc. Methods for the recovery of nucleic acids from reaction mixtures
US5155018A (en) 1991-07-10 1992-10-13 Hahnemann University Process and kit for isolating and purifying RNA from biological sources
US5329000A (en) 1991-10-31 1994-07-12 Becton, Dickinson And Company Purification of DNA with silicon tetrahydrazide
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
DE69324716T2 (de) 1992-02-13 1999-09-09 Becton Dickinson And Co. Celithydrat und Reinigung von DNS
US5223219A (en) 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples
US6953676B1 (en) 1992-05-01 2005-10-11 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5304487A (en) 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
US5296375A (en) 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5587128A (en) * 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5486335A (en) * 1992-05-01 1996-01-23 Trustees Of The University Of Pennsylvania Analysis based on flow restriction
US5409586A (en) 1992-08-26 1995-04-25 Hitachi, Ltd. Method for analyzing nucleic acid or protein and apparatus therefor
US5639423A (en) 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US5422271A (en) 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
US5798215A (en) 1993-02-18 1998-08-25 Biocircuits Corporation Device for use in analyte detection assays
US5399486A (en) 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
US5503985A (en) 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
US5427663A (en) 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
JP3035352B2 (ja) 1993-08-24 2000-04-24 メトリカ・インコーポレーテッド 新規な使い捨て電子検定ディバイス
US5438127A (en) 1993-09-27 1995-08-01 Becton Dickinson And Company DNA purification by solid phase extraction using a PCl3 modified glass fiber membrane
US5438129A (en) 1993-09-27 1995-08-01 Becton Dickinson And Company DNA purification by solid phase extraction using partially fluorinated aluminum hydroxide adsorbant
WO1995011755A1 (en) 1993-10-28 1995-05-04 Houston Advanced Research Center Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
US6129828A (en) 1996-09-06 2000-10-10 Nanogen, Inc. Apparatus and methods for active biological sample preparation
US5976824A (en) 1993-11-24 1999-11-02 Abbott Laboratories Method and apparatus for collecting a cell sample from a liquid specimen
DE69422604T2 (de) 1994-03-08 2000-06-08 Zeptosens Ag, Witterwil Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren
US5580435A (en) 1994-06-10 1996-12-03 The Board Of Trustees Of The Leland Stanford Junior University System for detecting components of a sample in electrophoretic separation
DE4420732A1 (de) 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
US5639428A (en) 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
WO1996007954A1 (en) 1994-09-09 1996-03-14 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Microstructures and methods for manufacturing microstructures
US5707799A (en) 1994-09-30 1998-01-13 Abbott Laboratories Devices and methods utilizing arrays of structures for analyte capture
US5500071A (en) 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5641400A (en) 1994-10-19 1997-06-24 Hewlett-Packard Company Use of temperature control devices in miniaturized planar column devices and miniaturized total analysis systems
CN1087960C (zh) 1994-10-22 2002-07-24 研究中心实验室(有限) 用于在不混溶流体之间进行扩散传递的方法与设备
CA2203630A1 (en) * 1994-11-08 1996-05-17 Bradley Michael John Stringer Human cell-lines
AUPM934994A0 (en) * 1994-11-09 1994-12-01 Commonwealth Scientific And Industrial Research Organisation Particle property measurement
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
IT1272932B (it) 1995-01-24 1997-07-01 Pier Giorgio Righetti Reattore ad enzima immobilizzato
NZ306051A (en) 1995-03-10 1999-11-29 Meso Scale Technologies Llc Testing using electrochemiluminescence
DE19519015C1 (de) 1995-05-24 1996-09-05 Inst Physikalische Hochtech Ev Miniaturisierter Mehrkammer-Thermocycler
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6168948B1 (en) 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
ATE360808T1 (de) 1995-07-13 2007-05-15 Applera Corp Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren
EP1291441A3 (de) 1995-09-12 2003-03-19 Becton, Dickinson and Company Verfahren und Vorrichtung zur DNS-Amplifikation und -Testung
US5660029A (en) * 1995-11-21 1997-08-26 King; Sidney E. Capsule filler
US5705018A (en) 1995-12-13 1998-01-06 Hartley; Frank T. Micromachined peristaltic pump
EP0780611A1 (de) * 1995-12-22 1997-06-25 Applied Materials, Inc. Durchflussregelventil
US5863502A (en) 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US5846727A (en) 1996-06-06 1998-12-08 Board Of Supervisors Of Louisiana State University And Agricultural & Mechanical College Microsystem for rapid DNA sequencing
US5863801A (en) 1996-06-14 1999-01-26 Sarnoff Corporation Automated nucleic acid isolation
US5779868A (en) 1996-06-28 1998-07-14 Caliper Technologies Corporation Electropipettor and compensation means for electrophoretic bias
JP3361530B2 (ja) 1996-06-28 2003-01-07 カリパー・テクノロジーズ・コープ． 電子ピペッタおよび電気泳動バイアスのための補償手段
US5946673A (en) * 1996-07-12 1999-08-31 Francone; Frank D. Computer implemented machine learning and control system
EP0826412A3 (de) 1996-08-26 1999-06-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin Verfahren zur Herstellung von Filterelementen und die damit hergestellen Filterelemente
US6716511B2 (en) * 1996-09-16 2004-04-06 Bp Corporation North America Inc. Propylene polymer fibers and yarns
US5874046A (en) 1996-10-30 1999-02-23 Raytheon Company Biological warfare agent sensor system employing ruthenium-terminated oligonucleotides complementary to target live agent DNA sequences
US5882903A (en) 1996-11-01 1999-03-16 Sarnoff Corporation Assay system and method for conducting assays
EP1030733A1 (de) 1997-02-05 2000-08-30 California Institute Of Technology Mikromischer für den unter-millisekunden-arbeitsbereich
WO1998038487A2 (en) 1997-02-28 1998-09-03 Cepheid Heat exchanging, optically interrogated chemical reaction assembly
EP0968434A2 (de) 1997-02-28 2000-01-05 Burstein Laboratories, Inc. Labor in einer platte
AU727083B2 (en) 1997-04-25 2000-11-30 Caliper Life Sciences, Inc. Microfluidic devices incorporating improved channel geometries
US6156273A (en) 1997-05-27 2000-12-05 Purdue Research Corporation Separation columns and methods for manufacturing the improved separation columns
US5869004A (en) 1997-06-09 1999-02-09 Caliper Technologies Corp. Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems
WO1999033559A1 (en) * 1997-12-24 1999-07-08 Cepheid Integrated fluid manipulation cartridge
JP2001515216A (ja) * 1997-08-13 2001-09-18 シーフィード 流体試料を操作するための微小構造体
US6117290A (en) * 1997-09-26 2000-09-12 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
US6106779A (en) * 1997-10-02 2000-08-22 Biosite Diagnostics, Inc. Lysis chamber for use in an assay device
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US6194222B1 (en) * 1998-01-05 2001-02-27 Biosite Diagnostics, Inc. Methods for monitoring the status of assays and immunoassays
US5993872A (en) * 1998-08-12 1999-11-30 Reno Rolle Deep fat fryer with ultrasonic rotational basket
US6100084A (en) 1998-11-05 2000-08-08 The Regents Of The University Of California Micro-sonicator for spore lysis
US6431476B1 (en) 1999-12-21 2002-08-13 Cepheid Apparatus and method for rapid ultrasonic disruption of cells or viruses
US6261431B1 (en) 1998-12-28 2001-07-17 Affymetrix, Inc. Process for microfabrication of an integrated PCR-CE device and products produced by the same
US6315957B1 (en) 1999-01-15 2001-11-13 Pharmacopeia, Inc. Article comprising a filter pocket-plate
US6056269A (en) * 1999-01-15 2000-05-02 Hewlett-Packard Company Microminiature valve having silicon diaphragm
US6138990A (en) * 1999-03-25 2000-10-31 Dxl Usa Inc. Flow control valve assembly for mass flow controller
FR2791697B1 (fr) 1999-04-01 2003-02-28 Biomerieux Sa Appareil et procede de lyse par ultrasons de cellules biologiques
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
US6391541B1 (en) * 1999-05-28 2002-05-21 Kurt E. Petersen Apparatus for analyzing a fluid sample
US20040200909A1 (en) 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US9073053B2 (en) 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
US6664104B2 (en) * 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
US6942169B2 (en) 2001-06-06 2005-09-13 Integrated Sensing Systems Micromachined lysing device and method for performing cell lysis
US6739531B2 (en) 2001-10-04 2004-05-25 Cepheid Apparatus and method for rapid disruption of cells or viruses

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US6783736B1 (en) 2004-08-31
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CA2373249A1 (en) 2000-12-07
US20120171758A1 (en) 2012-07-05
US20020019060A1 (en) 2002-02-14
WO2000073413A3 (en) 2001-01-25
DE60014676D1 (de) 2004-11-11
EP1208189A2 (de) 2002-05-29
US6881541B2 (en) 2005-04-19
EP1208189B1 (de) 2004-10-06
US20010012612A1 (en) 2001-08-09
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US9789481B2 (en) 2017-10-17
AU5170700A (en) 2000-12-18
WO2000073412A2 (en) 2000-12-07
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US20120009667A1 (en) 2012-01-12
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US8580559B2 (en) 2013-11-12
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US20080057572A1 (en) 2008-03-06
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