ATE304380T1 - Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung - Google Patents

Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung

Info

Publication number
ATE304380T1
ATE304380T1 AT01939381T AT01939381T ATE304380T1 AT E304380 T1 ATE304380 T1 AT E304380T1 AT 01939381 T AT01939381 T AT 01939381T AT 01939381 T AT01939381 T AT 01939381T AT E304380 T1 ATE304380 T1 AT E304380T1
Authority
AT
Austria
Prior art keywords
lyophilization
drug chamber
plug cap
drug
maintenance sleeve
Prior art date
Application number
AT01939381T
Other languages
English (en)
Inventor
Richard W Grabenkort
Randall M Farmer
Original Assignee
Hospira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hospira Inc filed Critical Hospira Inc
Application granted granted Critical
Publication of ATE304380T1 publication Critical patent/ATE304380T1/de

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106—Plugs for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3123—Details having air entrapping or venting means, e.g. purging channels in pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT01939381T 2000-05-31 2001-05-23 Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung ATE304380T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/584,307 US6440101B1 (en) 2000-05-31 2000-05-31 Syringe systems for lyophilized drugs and methods for making the same
PCT/US2001/016803 WO2001091836A2 (en) 2000-05-31 2001-05-23 Syringe systems for lyophilized drugs and methods for making the same

Publications (1)

Publication Number Publication Date
ATE304380T1 true ATE304380T1 (de) 2005-09-15

Family

ID=24336770

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01939381T ATE304380T1 (de) 2000-05-31 2001-05-23 Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung

Country Status (9)

Country Link
US (1) US6440101B1 (de)
EP (1) EP1289583B1 (de)
JP (1) JP2003535624A (de)
AT (1) ATE304380T1 (de)
AU (2) AU6490701A (de)
CA (1) CA2410468A1 (de)
DE (1) DE60113410T2 (de)
ES (1) ES2248338T3 (de)
WO (1) WO2001091836A2 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835191B2 (en) * 2001-12-21 2004-12-28 3M Innovative Properties Co. Self-venting movable seal and plunger
US7294119B2 (en) * 2004-06-10 2007-11-13 Safety Syringes, Inc. Passive delivery system diluents mixing and delivery
US7727195B2 (en) * 2004-07-01 2010-06-01 West Pharmaceutical Services, Inc. Syringe device having venting system
AT500930B1 (de) * 2004-10-25 2007-03-15 Pharma Consult Ges M B H & Co Verfahren und vorrichtung zum lyophilisieren, rekonstituieren und verabreichen eines rekonstituierten wirkstoffes
BRPI0515759B8 (pt) 2004-12-01 2021-06-22 Acushot Inc dispositivo de injeção sem agulha e kit para utilização do mesmo
US7959600B2 (en) * 2004-12-30 2011-06-14 Byeong S. Chang Container closure delivery system
US20060157507A1 (en) * 2004-12-30 2006-07-20 Chang Byeong S Multi-functional container closure delivery system
US20060144869A1 (en) * 2004-12-30 2006-07-06 Chang Byeong S Container closure delivery system
DE502005005547D1 (de) * 2005-07-15 2008-11-13 Dentaco Gmbh Pipettiervorrichtung
DE102005038368A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter zur Lyophilisation, Verfahren zu dessen Befüllung und dessen Verwendung
DE102005038495A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter und Verfahren zu dessen Befüllung
DE102005038458A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter ohne Bypass im zylindrischen Körper
DE102005038497A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter ohne Bypass
JP5456324B2 (ja) * 2006-02-14 2014-03-26 アーツナイミッテル・ゲーエムベーハー・アポテーカー・フェッター・ウント・コンパニー・ラフェンスブルク シリンジ
CA2652206C (en) 2006-05-25 2014-02-11 Bayer Healthcare Llc Reconstitution device
JP5140668B2 (ja) * 2006-08-09 2013-02-06 メッドミックス システムズ アーゲー ピストン付き注入器
JP4994775B2 (ja) 2006-10-12 2012-08-08 日本コヴィディエン株式会社 針先保護具
JP5113377B2 (ja) * 2006-12-20 2013-01-09 武蔵エンジニアリング株式会社 閉蓋具および液体材料貯留容器
US9044378B2 (en) 2007-05-31 2015-06-02 Safety Syringes, Inc. Anti-needle stick safety device or system for use with drugs requiring reconstitution
WO2009030342A1 (de) * 2007-08-28 2009-03-12 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Aufnahmevorrichtung
ES2589322T3 (es) 2008-02-11 2016-11-11 Safety Syringes, Inc. Jeringa con protector de seguridad de aguja y clip para evitar la liberación del protector durante un proceso de reconstitución
DE102008031809A1 (de) * 2008-06-27 2009-12-31 Optima Group Pharma Gmbh Halterung
US8371039B2 (en) * 2009-12-30 2013-02-12 Baxter International Inc. Thermal shielding to optimize lyophilization process for pre-filled syringes or vials
MX2013008031A (es) 2011-01-10 2014-05-13 Byeong Seon Chang Dispositivo de reconstitucion de medicamento compacto y metodo.
US8486024B2 (en) 2011-04-27 2013-07-16 Covidien Lp Safety IV catheter assemblies
GB201113606D0 (en) * 2011-08-05 2011-09-21 Norbrook Lab Ltd Dual chamber syringe
EP2760520A1 (de) 2011-09-26 2014-08-06 Covidien LP Sicherheitskatheter
WO2013048768A1 (en) 2011-09-26 2013-04-04 Covidien Lp Safety iv catheter and needle assembly
EP2766074B1 (de) 2011-10-14 2020-04-08 Kpr U.S., Llc Katheteranordnung der sicherheitsklasse iv
CN102961803B (zh) * 2012-10-30 2015-01-21 无锡耐思生物科技有限公司 一次性使用预灌封注射器
JP6514211B2 (ja) 2013-09-16 2019-05-15 ゾエティス・サービシーズ・エルエルシー 薬物を連続して送達するためのアセンブリ及び関連方法
KR102465054B1 (ko) 2014-09-09 2022-11-09 장병선 용액 전달 장치 및 방법
EP4729097A2 (de) * 2015-01-16 2026-04-22 Becton Dickinson France Arzneimittelaufbewahrungs- und -ausgabesystem für vorgefüllte behälter
US11911588B2 (en) * 2019-08-06 2024-02-27 Microvention, Inc. Syringe
JP7499090B2 (ja) * 2020-07-01 2024-06-13 テルモ株式会社 プレフィルドシリンジ、シリンジ組立体、プレフィルドシリンジの製造方法及び表面積増加方法
WO2024059819A2 (en) 2022-09-15 2024-03-21 Tff Pharmaceuticals, Inc. Compositions of cannabinoids for delivery by inhalation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3810469A (en) 1972-05-24 1974-05-14 Ampoules Inc Multiple compartment hypodermic devices
US4254768A (en) 1979-09-14 1981-03-10 Ty Perla J Hypodermic syringe
IT8222194U1 (it) 1982-06-18 1983-12-18 Edwards Alto Vuoto Spa Dispositivo per il caricamento delle piastre porta-prodotto di una camera di liofilizzazione mediante impiego di contenitori preposizionati ad altezza costante.
US4693706A (en) * 1986-08-11 1987-09-15 Mark L. Anderson Two compartment mixing syringe
US5364369A (en) * 1987-07-08 1994-11-15 Reynolds David L Syringe
SE9201247D0 (sv) 1992-04-21 1992-04-21 Kabi Pharmacia Ab Injection device
US5531683A (en) * 1992-08-13 1996-07-02 Science Incorporated Mixing and delivery syringe assembly
US5522804A (en) * 1994-02-15 1996-06-04 Lynn; Lawrence A. Aspiration, mixing, and injection syringe
DE4445969C1 (de) * 1994-12-22 1996-03-14 Schott Glaswerke Spritzenzylinder für eine Zweikammer-Fertigspritze, Zweikammer-Fertigspritze und Verfahren zum Herstellen und Füllen derselben
US5685846A (en) * 1995-02-27 1997-11-11 Schott Parenta Systems, Inc. Dual chamber internal by-pass syringe assembly
US5779668A (en) 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
DE19638940C2 (de) * 1996-09-23 1999-01-07 Vetter & Co Apotheker Vorgefüllte Spritze für medizinische Zwecke
US5865803A (en) * 1997-05-19 1999-02-02 Major; Miklos Syringe device having a vented piston
US5971953A (en) * 1998-01-09 1999-10-26 Bachynsky; Nicholas Dual chamber syringe apparatus

Also Published As

Publication number Publication date
EP1289583B1 (de) 2005-09-14
CA2410468A1 (en) 2001-12-06
AU2001264907B2 (en) 2005-07-21
DE60113410T2 (de) 2006-07-06
WO2001091836A3 (en) 2002-03-28
JP2003535624A (ja) 2003-12-02
ES2248338T3 (es) 2006-03-16
AU6490701A (en) 2001-12-11
EP1289583A2 (de) 2003-03-12
DE60113410D1 (de) 2005-10-20
WO2001091836A2 (en) 2001-12-06
US6440101B1 (en) 2002-08-27

Similar Documents

Publication Publication Date Title
ATE304380T1 (de) Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung
US5303835A (en) Lyophilization cap and method
NO953633D0 (no) Kassettsammenstilling for en lyofilisert forbindelse som danner en engangsdel av en injektorpenn og fremgangsmåte for samme
JP2008001430A (ja) 無菌製品のフラスコ用の栓及び無菌計量充填における当該栓の使用
ATE195916T1 (de) Verfahren zum füllen einer medizinkapsel und dabei erzeugter gegenstand
US10099012B2 (en) Closure system for an applicator attachment on a container for pharmaceutical preparations, and use, container with closure system, syringe for medical purposes, and method of assembly
US20170259948A1 (en) Closing a chamber of a container for a pharmaceutical product
AU2001249497B2 (en) Stoppering method to maintain sterility
US4253459A (en) Additive transfer unit with stabilized sealing means
DE69630444D1 (de) Spritze zur lyophilisation, rekonstitution und verabreichung
ES2038315T3 (es) Metodo de empaquetar y esterilizar un producto farmaceutico en el correspondiente envase.
US4200100A (en) Additive transfer unit with piercing member having a penetratable protective tip
US11027861B2 (en) Needle free syringe and pre-filling system
RU2011101687A (ru) Способ заполнения двухкамерных систем в предварительно стерилизуемых несущих системах и предварительно стерилизуемая несущая система
JPH09285540A (ja) 容器兼用注射器
JP3015285B2 (ja) 注射器兼容器
JP3015284B2 (ja) 注射器兼容器
JPH05305140A (ja) 注射器の注射筒の栓体と該栓体の抜け防止具
CN103721320A (zh) 安全注射器
CN1130356A (zh) 制备药物溶液、悬液或乳液的装置
CN211024555U (zh) 一种适用于油性安剖瓶容纳药品的注射器
JP2721949B2 (ja) 薬品容器兼注射器における注射筒本体の凍結乾燥用のホルダー
CN205924522U (zh) 一种用于中药提取物的高压灭菌及存储瓶
CN201263818Y (zh) 溶质瓶另置式粉针剂注射器
CN201098355Y (zh) 液体药瓶防污染瓶盖

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties