ATE307826T1 - Oligomere von konformationsbeschränkten, nicht- peptidischen di- oder tripeptid-mimetika, und ihre verwendung zur synthese von künstlichen polypeptiden und proteinen - Google Patents
Oligomere von konformationsbeschränkten, nicht- peptidischen di- oder tripeptid-mimetika, und ihre verwendung zur synthese von künstlichen polypeptiden und proteinenInfo
- Publication number
- ATE307826T1 ATE307826T1 AT01903924T AT01903924T ATE307826T1 AT E307826 T1 ATE307826 T1 AT E307826T1 AT 01903924 T AT01903924 T AT 01903924T AT 01903924 T AT01903924 T AT 01903924T AT E307826 T1 ATE307826 T1 AT E307826T1
- Authority
- AT
- Austria
- Prior art keywords
- oligomers
- peptide
- synthesis
- fragment
- proteins
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 abstract 3
- 108010016626 Dipeptides Proteins 0.000 abstract 1
- 102000007079 Peptide Fragments Human genes 0.000 abstract 1
- 108010033276 Peptide Fragments Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000010647 peptide synthesis reaction Methods 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyrrole Compounds (AREA)
- Polyamides (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0000288A FR2803594B1 (fr) | 2000-01-11 | 2000-01-11 | Oligomeres de mimes contraints non peptidiques de dipeptides ou de tripeptides, et leurs utilisations |
| PCT/FR2001/000088 WO2001051506A2 (fr) | 2000-01-11 | 2001-01-11 | Oligomeres de mimes contraints non peptidiques de dipeptides ou de tripeptides, et leur utilisation pour la synthese de proteines et polypeptides artificiels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE307826T1 true ATE307826T1 (de) | 2005-11-15 |
Family
ID=8845781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01903924T ATE307826T1 (de) | 2000-01-11 | 2001-01-11 | Oligomere von konformationsbeschränkten, nicht- peptidischen di- oder tripeptid-mimetika, und ihre verwendung zur synthese von künstlichen polypeptiden und proteinen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030191049A1 (de) |
| EP (1) | EP1246837B1 (de) |
| JP (1) | JP2003519629A (de) |
| AT (1) | ATE307826T1 (de) |
| AU (1) | AU2001231881A1 (de) |
| DE (1) | DE60114363D1 (de) |
| FR (1) | FR2803594B1 (de) |
| WO (1) | WO2001051506A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2175273B1 (de) * | 2005-11-09 | 2013-09-04 | Ajinomoto Co., Inc. | Kokumi-Verleihungsmittel |
| DE102009032902A1 (de) * | 2009-07-10 | 2011-01-13 | Forschungsverbund Berlin E.V. | Induktion von α-Helix-Konformationen in Proteinen und Peptiden |
| FR2948571B1 (fr) * | 2009-07-31 | 2013-02-22 | Centre Nat Rech Scient | Utilisation d'oligomeres mimes contraints de dipeptides et tripeptides en tant qu'agents de vectorisation |
| WO2012021144A1 (en) | 2010-08-12 | 2012-02-16 | New York University | Oligooxopiperazines and methods of making and using them |
| CN104334541A (zh) * | 2012-02-16 | 2015-02-04 | 纽约大学 | 使用低聚氧代哌嗪非肽螺旋模拟物对低氧诱导基因表达的控制 |
| US9546174B2 (en) | 2012-11-30 | 2017-01-17 | Sanford-Burnham Medical Research Institute | Inhibitor of apoptosis protein (IAP) antagonists |
| WO2014113794A2 (en) | 2013-01-19 | 2014-07-24 | New York University | Oligooxopiperazines for p53 reactivation |
| US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
| CA2907454C (en) | 2013-03-21 | 2021-05-04 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
| US11180481B2 (en) | 2014-04-15 | 2021-11-23 | New York University | Oxopiperazine helix mimetics as inhibitors of the p53-MDM2 interaction |
| US10787424B2 (en) | 2014-05-21 | 2020-09-29 | New York University | Oxopiperazine helix mimetics for control of Hypoxia-Inducible gene expression |
| IL287136B2 (en) | 2016-02-05 | 2023-09-01 | Denali Therapeutics Inc | Receptor inhibitors - interacting with protein kinase 1 |
| JP7208137B2 (ja) | 2016-12-09 | 2023-01-18 | デナリ セラピューティクス インコーポレイテッド | 化合物、組成物および方法 |
| US10822371B2 (en) | 2017-12-06 | 2020-11-03 | Bracco Imaging S.P.A. | Solid phase synthesis of NIR fluorescent probe |
| TW202334164A (zh) | 2022-01-12 | 2023-09-01 | 美商戴納立製藥公司 | (S)-5-苄基-N-(5-甲基-4-側氧基-2,3,4,5-四氫吡啶並[3,2-b][1,4]氧氮呯-3-基)-4H-1,2,4-三唑-3-甲醯胺的晶型 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3716629C2 (de) * | 1987-05-18 | 1997-06-12 | Siemens Ag | Wärmebeständige positiv arbeitende strahlungsempfindliche Gemische und Verfahren zur Herstellung wärmebeständiger Reliefstrukturen |
| US6090947A (en) * | 1996-02-26 | 2000-07-18 | California Institute Of Technology | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support |
| AUPP254898A0 (en) * | 1998-03-24 | 1998-04-23 | University Of Queensland, The | Peptide turn mimetics |
-
2000
- 2000-01-11 FR FR0000288A patent/FR2803594B1/fr not_active Expired - Fee Related
-
2001
- 2001-01-11 AU AU2001231881A patent/AU2001231881A1/en not_active Abandoned
- 2001-01-11 AT AT01903924T patent/ATE307826T1/de not_active IP Right Cessation
- 2001-01-11 WO PCT/FR2001/000088 patent/WO2001051506A2/fr not_active Ceased
- 2001-01-11 DE DE60114363T patent/DE60114363D1/de not_active Expired - Lifetime
- 2001-01-11 US US10/169,907 patent/US20030191049A1/en not_active Abandoned
- 2001-01-11 JP JP2001551090A patent/JP2003519629A/ja active Pending
- 2001-01-11 EP EP01903924A patent/EP1246837B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003519629A (ja) | 2003-06-24 |
| EP1246837B1 (de) | 2005-10-26 |
| WO2001051506A2 (fr) | 2001-07-19 |
| EP1246837A2 (de) | 2002-10-09 |
| FR2803594A1 (fr) | 2001-07-13 |
| DE60114363D1 (de) | 2005-12-01 |
| FR2803594B1 (fr) | 2002-07-19 |
| WO2001051506A3 (fr) | 2002-02-07 |
| AU2001231881A1 (en) | 2001-07-24 |
| US20030191049A1 (en) | 2003-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |