ATE308984T1 - Arzneiformen zur behandlung von krankheiten, die auf aktivierung des ppar-gamma-rezeptors ansprechen - Google Patents

Arzneiformen zur behandlung von krankheiten, die auf aktivierung des ppar-gamma-rezeptors ansprechen

Info

Publication number: ATE308984T1
Authority: AT; Austria
Prior art keywords: activation; treatment; ppar; gamma receptor; diseases responsive
Prior art date: 2001-03-16

Application number

AT02717031T

Other languages

English (en)

Inventor

C. Pisano

T Riccioni

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-16

Filing date

2002-03-01

Publication date

2005-11-15

2002-03-01 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

2005-11-15 Application granted granted Critical

2005-11-15 Publication of ATE308984T1 publication Critical patent/ATE308984T1/de

Links

230000004913 activation Effects 0.000 title abstract 3
201000010099 disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
CZIMFHQXGMXDMO-DGROVODQSA-N (3r)-5-hydroxy-7-methoxy-3-[5-[(2r,5r,7r)-2-methyl-1,6-dioxaspiro[4.5]decan-7-yl]pentyl]-3h-2-benzofuran-1-one Chemical compound C([C@H](O1)CCCCC[C@@H]2C=3C=C(O)C=C(C=3C(=O)O2)OC)CC[C@@]21CC[C@@H](C)O2 CZIMFHQXGMXDMO-DGROVODQSA-N 0.000 abstract 2
102000000536 PPAR gamma Human genes 0.000 abstract 2
108010016731 PPAR gamma Proteins 0.000 abstract 2
CZIMFHQXGMXDMO-UHFFFAOYSA-N Spirolaxine Natural products O1C(=O)C=2C(OC)=CC(O)=CC=2C1CCCCCC(O1)CCCC21CCC(C)O2 CZIMFHQXGMXDMO-UHFFFAOYSA-N 0.000 abstract 2
230000007170 pathology Effects 0.000 abstract 2
206010022491 Insulin resistant diabetes Diseases 0.000 abstract 1
230000001154 acute effect Effects 0.000 abstract 1
SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
230000003211 malignant effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229930002330 retinoic acid Natural products 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)

AT02717031T 2001-03-16 2002-03-01 Arzneiformen zur behandlung von krankheiten, die auf aktivierung des ppar-gamma-rezeptors ansprechen ATE308984T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2001RM000136A ITRM20010136A1 (it)	2001-03-16	2001-03-16	Composti utili per il trattamento di patologie che rispondono all'attivazione del recettore ppar-gamma.
PCT/IT2002/000127 WO2002074291A2 (en)	2001-03-16	2002-03-01	Compositions useful for the treatment of pathologies responding to the activation of ppar-gamma receptor

Publications (1)

Publication Number	Publication Date
ATE308984T1 true ATE308984T1 (de)	2005-11-15

Family

ID=11455333

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02717031T ATE308984T1 (de)	2001-03-16	2002-03-01	Arzneiformen zur behandlung von krankheiten, die auf aktivierung des ppar-gamma-rezeptors ansprechen

Country Status (19)

Country	Link
US (4)	US6897235B2 (de)
EP (1)	EP1368025B1 (de)
JP (1)	JP4276842B2 (de)
KR (1)	KR100851678B1 (de)
CN (2)	CN100462073C (de)
AT (1)	ATE308984T1 (de)
AU (1)	AU2002247951B2 (de)
BR (1)	BR0208157A (de)
CA (1)	CA2440979C (de)
CZ (1)	CZ20032523A3 (de)
DE (1)	DE60207215T2 (de)
DK (1)	DK1368025T3 (de)
ES (1)	ES2249568T3 (de)
HU (1)	HUP0303518A3 (de)
IT (1)	ITRM20010136A1 (de)
MX (1)	MXPA03008317A (de)
PL (1)	PL369295A1 (de)
SK (1)	SK12752003A3 (de)
WO (1)	WO2002074291A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7041691B1 (en)	1999-06-30	2006-05-09	Amgen Inc.	Compounds for the modulation of PPARγ activity
US20030171399A1 (en)	2000-06-28	2003-09-11	Tularik Inc.	Quinolinyl and benzothiazolyl modulators
US20070082947A1 (en) *	2003-05-14	2007-04-12	D Orazio Daniel	Use of phthalide derivatives for the treatment and prevention of diabetes mellitus
US7223761B2 (en)	2003-10-03	2007-05-29	Amgen Inc.	Salts and polymorphs of a potent antidiabetic compound
CA2663121C (en)	2006-09-08	2016-01-19	Rhode Island Hospital	Treatment, prevention, and reversal of alcohol-induced brain disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07285862A (ja) *	1994-04-21	1995-10-31	Kokka Iyaku Kanrikyoku Shisen Kokinso Kogyo Kenkyusho	脂質低下剤
JPH107557A (ja) *	1996-06-17	1998-01-13	Banyu Pharmaceut Co Ltd	抗腫瘍性物質スピロラキシン
US6440961B1 (en) *	1997-10-27	2002-08-27	Dr. Reddy's Research Foundation	Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
IT1317001B1 (it) *	2000-03-13	2003-05-26	Sigma Tau Ind Farmaceuti	Uso della spirolaxina per il trattamento di patologie associate ad unaalterata angiogenesi.

2001
- 2001-03-16 IT IT2001RM000136A patent/ITRM20010136A1/it unknown
2002
- 2002-03-01 CZ CZ20032523A patent/CZ20032523A3/cs unknown
- 2002-03-01 JP JP2002572999A patent/JP4276842B2/ja not_active Expired - Fee Related
- 2002-03-01 WO PCT/IT2002/000127 patent/WO2002074291A2/en not_active Ceased
- 2002-03-01 ES ES02717031T patent/ES2249568T3/es not_active Expired - Lifetime
- 2002-03-01 EP EP02717031A patent/EP1368025B1/de not_active Expired - Lifetime
- 2002-03-01 CA CA2440979A patent/CA2440979C/en not_active Expired - Fee Related
- 2002-03-01 MX MXPA03008317A patent/MXPA03008317A/es active IP Right Grant
- 2002-03-01 AT AT02717031T patent/ATE308984T1/de not_active IP Right Cessation
- 2002-03-01 CN CNB2006100057819A patent/CN100462073C/zh not_active Expired - Fee Related
- 2002-03-01 CN CNB028081382A patent/CN1286456C/zh not_active Expired - Fee Related
- 2002-03-01 US US10/471,786 patent/US6897235B2/en not_active Expired - Fee Related
- 2002-03-01 KR KR1020037012030A patent/KR100851678B1/ko not_active Expired - Fee Related
- 2002-03-01 BR BR0208157-1A patent/BR0208157A/pt not_active IP Right Cessation
- 2002-03-01 AU AU2002247951A patent/AU2002247951B2/en not_active Ceased
- 2002-03-01 HU HU0303518A patent/HUP0303518A3/hu unknown
- 2002-03-01 DE DE60207215T patent/DE60207215T2/de not_active Expired - Lifetime
- 2002-03-01 PL PL02369295A patent/PL369295A1/xx not_active Application Discontinuation
- 2002-03-01 SK SK1275-2003A patent/SK12752003A3/sk unknown
- 2002-03-01 DK DK02717031T patent/DK1368025T3/da active
2004
- 2004-07-13 US US10/889,029 patent/US7276533B2/en not_active Expired - Fee Related
- 2004-07-13 US US10/889,030 patent/US20040242675A1/en not_active Abandoned
- 2004-10-18 US US10/965,740 patent/US20050131060A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20040241228A1 (en)	2004-12-02
US20040092540A1 (en)	2004-05-13
DE60207215D1 (de)	2005-12-15
WO2002074291A2 (en)	2002-09-26
US7276533B2 (en)	2007-10-02
HUP0303518A3 (en)	2005-12-28
CN1610545A (zh)	2005-04-27
SK12752003A3 (sk)	2004-01-08
ES2249568T3 (es)	2006-04-01
HK1096850A1 (zh)	2007-06-15
AU2002247951B2 (en)	2007-03-01
CN1286456C (zh)	2006-11-29
CA2440979C (en)	2010-07-13
HK1075006A1 (en)	2005-12-02
CA2440979A1 (en)	2002-09-26
US6897235B2 (en)	2005-05-24
US20050131060A1 (en)	2005-06-16
CN1839823A (zh)	2006-10-04
KR100851678B1 (ko)	2008-08-13
US20040242675A1 (en)	2004-12-02
DE60207215T2 (de)	2006-07-20
EP1368025A2 (de)	2003-12-10
JP2004523578A (ja)	2004-08-05
MXPA03008317A (es)	2003-12-11
PL369295A1 (en)	2005-04-18
EP1368025B1 (de)	2005-11-09
WO2002074291A3 (en)	2003-03-13
ITRM20010136A1 (it)	2002-09-16
CZ20032523A3 (cs)	2004-05-12
DK1368025T3 (da)	2005-12-19
CN100462073C (zh)	2009-02-18
ITRM20010136A0 (it)	2001-03-16
JP4276842B2 (ja)	2009-06-10
KR20040025905A (ko)	2004-03-26
BR0208157A (pt)	2004-03-02
HUP0303518A2 (hu)	2004-03-01

Legal Events

Date

Code

Title

Description

2006-10-15

UEP

Publication of translation of european patent specification

Ref document number: 1368025

Country of ref document: EP

2011-12-15

REN

Ceased due to non-payment of the annual fee

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