ATE309228T1 - Isoxazolderivate - Google Patents

Isoxazolderivate

Info

Publication number: ATE309228T1
Authority: AT; Austria
Prior art keywords: group; formula; represented; solid line; single bond
Prior art date: 1997-04-21

Application number

AT98914071T

Other languages

English (en)

Inventor

Masashi Nakatsuka

Yoshihide Ueno

Shin-Ichiro Okada

Fumio Nishikaku

Original Assignee

Sumitomo Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-21

Filing date

1998-04-17

Publication date

2005-11-15

1998-04-17 Application filed by Sumitomo Pharma filed Critical Sumitomo Pharma

2005-11-15 Application granted granted Critical

2005-11-15 Publication of ATE309228T1 publication Critical patent/ATE309228T1/de

Links

CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical class C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
208000023275 Autoimmune disease Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
150000002545 isoxazoles Chemical class 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940126585 therapeutic drug Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Physical Education & Sports Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

AT98914071T 1997-04-21 1998-04-17 Isoxazolderivate ATE309228T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP11887197		1997-04-21
JP36715497		1997-12-24
PCT/JP1998/001770 WO1998047880A1 (en)	1997-04-21	1998-04-17	Isoxazole derivatives

Publications (1)

Publication Number	Publication Date
ATE309228T1 true ATE309228T1 (de)	2005-11-15

Family

ID=26456721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98914071T ATE309228T1 (de)	1997-04-21	1998-04-17	Isoxazolderivate

Country Status (14)

Country	Link
EP (1)	EP0979226B1 (de)
KR (1)	KR100512087B1 (de)
CN (1)	CN1138764C (de)
AT (1)	ATE309228T1 (de)
AU (1)	AU733091B2 (de)
CA (1)	CA2235298C (de)
DE (1)	DE69832270T2 (de)
DK (1)	DK0979226T3 (de)
ES (1)	ES2248894T3 (de)
ID (1)	ID22897A (de)
NZ (1)	NZ330244A (de)
RU (1)	RU2196770C2 (de)
TW (1)	TW442476B (de)
WO (1)	WO1998047880A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2377527A1 (en) *	1999-07-15	2001-01-25	Sumitomo Pharmaceuticals Co., Ltd.	Heteroaromatic ring compounds
WO2001047895A1 (en) *	1999-12-28	2001-07-05	Sumitomo Pharmaceuticals Company, Limited	Novel compounds having five-membered hetero-aromatic rings
GB0010183D0 (en) *	2000-04-26	2000-06-14	Ferring Bv	Inhibitors of dipeptidyl peptidase IV
CN100522174C (zh) *	2001-03-27	2009-08-05	大日本住友制药株式会社	结晶异唑衍生物及其药物制剂
JPWO2003068239A1 (ja) *	2002-02-12	2005-06-02	住友製薬株式会社	新規外用剤
AU2004244626A1 (en) *	2003-05-23	2004-12-09	The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services	GITR ligand and GITR ligand-related molecules and antibodies and uses thereof
ITMI20040019A1 (it) *	2004-01-12	2004-04-12	Univ Bari	Derivati isossazolici e loro impiego come inibitori della ciclossigenasi
DE102004008141A1 (de)	2004-02-19	2005-09-01	Abbott Gmbh & Co. Kg	Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren
WO2006049215A1 (ja) *	2004-11-02	2006-05-11	Dainippon Sumitomo Pharma Co., Ltd.	自己免疫疾患を治療するための併用薬
US7989450B2 (en)	2008-01-11	2011-08-02	Universita' Degli Studi Di Bari	Functionalized diarylisoxazoles inhibitors of ciclooxygenase
CN103476771B (zh) *	2011-01-28	2015-12-23	4Sc探索有限责任公司	用于治疗自身免疫炎症的IL17和IFN-γ抑制
DE102014201651A1 (de)	2014-01-30	2015-07-30	Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin	Isoxazolderivate zur Verwendung bei der Behandlung und/oder Prophylaxe von Herzerkrankungen
CN111269149B (zh) *	2020-04-08	2022-04-15	南京优氟医药科技有限公司	一种5-(3,3-二甲基胍基)-2-氧代戊酸的生产工艺
CN114478350B (zh) *	2022-01-25	2023-08-11	苏州大学	一种c3-烷基化吲哚的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2068418A1 (en) *	1969-10-27	1971-08-27	Innothera Lab Sa	2-substd-5-amino isoxazole derivs
US3720685A (en) *	1970-07-15	1973-03-13	Squibb & Sons Inc	3-amino-5-benzyl-1,2,4-oxadiazoles
GB1338169A (en) *	1971-03-09	1973-11-21	Smith Kline French Lab	Ureas thioureas and guanidines
DE2341507A1 (de) *	1973-08-16	1975-02-27	Thomae Gmbh Dr K	Neue biphenylderivate und verfahren zur herstellung
JPS54144347A (en) *	1978-05-02	1979-11-10	Nikken Kagaku Kk	3-(2-fluoro-4-biphenylyl)-2-butanone
HU180567B (en) *	1980-03-19	1983-03-28	Egyt Gyogyszervegyeszeti Gyar	Method for producing derivatives of isooxazole
US4399075A (en) *	1981-06-25	1983-08-16	Asahi Chemical Company, Limited	Process for producing chlorinated phenoxytoluene derivatives
JPS58150576A (ja) *	1982-03-03	1983-09-07	Sumitomo Chem Co Ltd	新規な１，２，４−オキサジアゾ−ル誘導体
US4680300A (en) *	1985-01-10	1987-07-14	Syntex (U.S.A.) Inc.	Anti-inflammatory guanidines
US4914112A (en) *	1986-06-03	1990-04-03	Sumitomo Pharmaceuticals Company, Limited	Aminoazole derivatives and their production and use
EP0292937B1 (de) *	1987-05-26	1994-08-10	Sumitomo Chemical Company, Limited	Amidderivate, ihre Herstellung und landwirtschaftliche Fungizide, die sie enthalten
JP2719742B2 (ja) *	1991-04-30	1998-02-25	株式会社大塚製薬工場	フェニルチアゾール誘導体
US5514643A (en) *	1993-08-16	1996-05-07	Lucky Ltd.	2-aminothiazolecarboxamide derivatives, processes for preparing the same and use thereof for controlling phytopathogenic organisms

1998
- 1998-04-17 EP EP98914071A patent/EP0979226B1/de not_active Expired - Lifetime
- 1998-04-17 WO PCT/JP1998/001770 patent/WO1998047880A1/en not_active Ceased
- 1998-04-17 KR KR10-1999-7009591A patent/KR100512087B1/ko not_active Expired - Fee Related
- 1998-04-17 DE DE69832270T patent/DE69832270T2/de not_active Expired - Lifetime
- 1998-04-17 DK DK98914071T patent/DK0979226T3/da active
- 1998-04-17 AU AU61934/98A patent/AU733091B2/en not_active Ceased
- 1998-04-17 AT AT98914071T patent/ATE309228T1/de active
- 1998-04-17 CN CNB98804398XA patent/CN1138764C/zh not_active Expired - Fee Related
- 1998-04-17 ID IDW991245A patent/ID22897A/id unknown
- 1998-04-17 ES ES98914071T patent/ES2248894T3/es not_active Expired - Lifetime
- 1998-04-20 CA CA002235298A patent/CA2235298C/en not_active Expired - Fee Related
- 1998-04-20 RU RU98107337/04A patent/RU2196770C2/ru not_active IP Right Cessation
- 1998-04-20 TW TW087106014A patent/TW442476B/zh not_active IP Right Cessation
- 1998-04-21 NZ NZ330244A patent/NZ330244A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20010006501A (ko)	2001-01-26
NZ330244A (en)	2000-01-28
ES2248894T3 (es)	2006-03-16
TW442476B (en)	2001-06-23
CN1252794A (zh)	2000-05-10
AU6193498A (en)	1998-10-22
EP0979226B1 (de)	2005-11-09
DK0979226T3 (da)	2006-03-06
CN1138764C (zh)	2004-02-18
RU2196770C2 (ru)	2003-01-20
KR100512087B1 (ko)	2005-09-05
EP0979226A1 (de)	2000-02-16
DE69832270T2 (de)	2006-07-13
AU733091B2 (en)	2001-05-03
DE69832270D1 (de)	2005-12-15
CA2235298A1 (en)	1998-10-21
WO1998047880A1 (en)	1998-10-29
CA2235298C (en)	2008-05-13
ID22897A (id)	1999-12-16

Legal Events

Date	Code	Title	Description
2006-08-15	EEIH	Change in the person of patent owner

Publication	Publication Date	Title
DE69832270D1 (de)	2005-12-15	Isoxazolderivate
DK0889876T3 (da)	2001-09-24	Meta-substituerede phenylensulfonamidderivater
EP1070710A3 (de)	2001-03-21	Dithiolan Derivate, deren Herstellung und deren therapeutischer Wirkung
ATE193828T1 (de)	2000-06-15	Hypoglykämische dihydrochalconderivate
TW349098B (en)	1999-01-01	Naphthalene derivatives, process for the preparation thereof, and intermediates therefor
DK0736018T3 (da)	2000-09-18	4,5-Diaryloxazolderivater
EA199800141A1 (ru)	1998-08-27	Гетероциклические соединения
DE69418243D1 (de)	1999-06-10	N-Heteroaryl-N'-Phenylharnstoffderivate, ihre Herstellung und Verwendung
ATE466861T1 (de)	2010-05-15	Aminderivate
DK1004573T3 (da)	2003-03-03	Aryloxyanilinderivater
ATE289810T1 (de)	2005-03-15	Ecteinascidinderivate
NO964045D0 (no)	1996-09-26	Sulfonamidderivater
TR200001239T2 (tr)	2001-07-23	Tiyazolidinediyon türevlerini hazırlama prosesi.
ES2055235T3 (es)	1994-08-16	Composicion anti-inflamatoria y/o antialergica que comprende derivados de glutation.
DK0420121T3 (da)	1993-05-03	Antitumormiddel
DE60107832D1 (en)	2005-01-20	Chromenylmethylpyrimidindiamine als antibakterielle wirkstoffe
KR920004392A (ko)	1992-03-27	플루오로에틸캄프토테신 유도체
EP0335979A4 (en)	1992-02-26	Thienopyrimidine derivatives
ATE86117T1 (de)	1993-03-15	Zusammensetzung gegen leberkrankheiten.
AU1424795A (en)	1995-08-01	Indole derivative
EP0302633A3 (de)	1990-03-14	Beta-Lactamverbindungen, Verfahren zu ihrer Herstellung, Zwischenprodukte für ihre Synthese und diese enthaltende pharmazeutische Präparate für bakterielle Infektionskrankheitentherapie
DK378087D0 (da)	1987-07-20	Tetracycliske indolderivater
ATE92071T1 (de)	1993-08-15	Biphenylderivate.
EP1184367A4 (de)	2002-11-13	Amid-derivate