ATE309802T1 - Verwendung von cyclopamine zur behandlung von psoriasis und anderen hauterkrankungen - Google Patents

Verwendung von cyclopamine zur behandlung von psoriasis und anderen hauterkrankungen

Info

Publication number
ATE309802T1
ATE309802T1 AT03723620T AT03723620T ATE309802T1 AT E309802 T1 ATE309802 T1 AT E309802T1 AT 03723620 T AT03723620 T AT 03723620T AT 03723620 T AT03723620 T AT 03723620T AT E309802 T1 ATE309802 T1 AT E309802T1
Authority
AT
Austria
Prior art keywords
cyclopamine
corticosteroid
skin
lesions
treatment
Prior art date
Application number
AT03723620T
Other languages
English (en)
Inventor
Sinan Tas
Oktay Avci
Original Assignee
Sinan Tas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29247069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE309802(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/TR2002/000017 external-priority patent/WO2002078704A1/en
Application filed by Sinan Tas filed Critical Sinan Tas
Application granted granted Critical
Publication of ATE309802T1 publication Critical patent/ATE309802T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT03723620T 2002-04-19 2003-03-17 Verwendung von cyclopamine zur behandlung von psoriasis und anderen hauterkrankungen ATE309802T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/TR2002/000017 WO2002078704A1 (en) 2001-07-02 2002-04-19 Use of cyclopamine in the treatment of psoriasis
PCT/TR2003/000017 WO2003088964A1 (en) 2002-04-19 2003-03-17 Use of cyclopamine in the treatment of psoriasis and other skin disorders

Publications (1)

Publication Number Publication Date
ATE309802T1 true ATE309802T1 (de) 2005-12-15

Family

ID=29247069

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03723620T ATE309802T1 (de) 2002-04-19 2003-03-17 Verwendung von cyclopamine zur behandlung von psoriasis und anderen hauterkrankungen

Country Status (15)

Country Link
US (6) US7605167B2 (de)
EP (2) EP1411938B1 (de)
JP (1) JP2006512281A (de)
KR (4) KR20040102117A (de)
CN (2) CN101642458A (de)
AT (1) ATE309802T1 (de)
AU (1) AU2003230541B2 (de)
BR (1) BR0309396A (de)
CA (3) CA2452152A1 (de)
DE (1) DE60302348T2 (de)
DK (1) DK1496895T3 (de)
EA (1) EA200401355A1 (de)
ES (1) ES2253672T3 (de)
MX (1) MXPA04010294A (de)
WO (1) WO2003088964A1 (de)

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US8044259B2 (en) 2000-08-03 2011-10-25 The Regents Of The University Of Michigan Determining the capability of a test compound to affect solid tumor stem cells
US20170326118A1 (en) * 2001-07-02 2017-11-16 Sinan Tas Drug treatment of tumors wherein hedgehog/smoothened signaling is utilized for inhibition of apoptosis of tumor cells
JP2004536045A (ja) * 2001-07-02 2004-12-02 タシ、シナン 基底細胞癌及び他の腫瘍の治療におけるシクロパミンの使用方法
EP1411938B1 (de) * 2001-07-02 2005-07-06 Tas, Sinan Verwendung von cyclopamine zur Herstellung eines Arzneimittels zur Behandlung von Psoriasis
EP2316832B1 (de) * 2004-08-27 2017-03-08 Infinity Pharmaceuticals, Inc. Cyclopamin Analogverbindungen, deren Herstellungsverfahren und Anwendung
US20070281040A1 (en) * 2004-09-30 2007-12-06 The University Of Chicago Combination therapy of hedgehog inhibitors, radiation and chemotherapeutic agents
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EP2129677B1 (de) * 2007-03-07 2014-12-17 Infinity Discovery, Inc. Heterocyclische cyclopamin-analoga und verfahren zu ihrer verwendung
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CN101917853B (zh) * 2007-12-27 2014-03-19 无限药品股份有限公司 立体选择性还原的方法
WO2009099625A2 (en) * 2008-02-08 2009-08-13 The Board Of Regents Of The University Of Texas System Cyclopamine tartrate salt and uses thereof
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US20110183948A1 (en) * 2010-01-15 2011-07-28 Infinity Pharmaceuticals, Inc. Treatment of fibrotic conditions using hedgehog inhibitors
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CN110520097B (zh) 2017-01-06 2023-10-27 帕尔维拉治疗股份有限公司 Mtor抑制剂的无水组合物及其使用方法
JP2021530463A (ja) 2018-07-02 2021-11-11 パルヴェラ セラピューティクス、インク. mTOR阻害剤の無水組成物および使用方法
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EP4358955A4 (de) * 2021-06-21 2025-01-08 Palvella Therapeutics, Inc. Verfahren und zusammensetzungen zur behandlung des gorlin-syndroms
CN117940170A (zh) 2021-09-13 2024-04-26 辛南·塔斯 有效干预人类衰老和衰老疾病及其效果

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EP1411938B1 (de) * 2001-07-02 2005-07-06 Tas, Sinan Verwendung von cyclopamine zur Herstellung eines Arzneimittels zur Behandlung von Psoriasis
JP2004536045A (ja) * 2001-07-02 2004-12-02 タシ、シナン 基底細胞癌及び他の腫瘍の治療におけるシクロパミンの使用方法
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Also Published As

Publication number Publication date
CA2481499A1 (en) 2003-10-30
US20110104254A1 (en) 2011-05-05
ES2253672T3 (es) 2006-06-01
KR20080096605A (ko) 2008-10-30
EP1496895A1 (de) 2005-01-19
CA2452152A1 (en) 2002-10-10
KR20040102117A (ko) 2004-12-03
US20080090790A1 (en) 2008-04-17
MXPA04010294A (es) 2005-05-17
CA2636960A1 (en) 2003-10-30
BR0309396A (pt) 2005-02-09
US20040072914A1 (en) 2004-04-15
KR20070108287A (ko) 2007-11-08
WO2003088964A1 (en) 2003-10-30
JP2006512281A (ja) 2006-04-13
DE60302348D1 (de) 2005-12-22
US7893078B2 (en) 2011-02-22
AU2003230541B2 (en) 2006-06-29
US20040072913A1 (en) 2004-04-15
DE60302348T2 (de) 2006-07-27
US20090286822A1 (en) 2009-11-19
CA2636960C (en) 2013-12-31
EP1411938B1 (de) 2005-07-06
US7605167B2 (en) 2009-10-20
EP1496895B1 (de) 2005-11-16
US9757361B2 (en) 2017-09-12
US7629352B2 (en) 2009-12-08
DK1496895T3 (da) 2006-03-27
EA200401355A1 (ru) 2005-06-30
KR20080094739A (ko) 2008-10-23
US20100048725A2 (en) 2010-02-25
US8025893B2 (en) 2011-09-27
CA2481499C (en) 2013-05-21
CN101642458A (zh) 2010-02-10
AU2003230541A1 (en) 2003-11-03
EP1411938A1 (de) 2004-04-28
US20080089915A1 (en) 2008-04-17
CN1835748A (zh) 2006-09-20

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