DK1496895T3 - Anvendelse af cyclopamin til behandling af psoriasis og andre hudlidelser - Google Patents

Anvendelse af cyclopamin til behandling af psoriasis og andre hudlidelser

Info

Publication number: DK1496895T3
Authority: DK; Denmark
Prior art keywords: cyclopamine; treatment; corticosteroid; skin; lesions
Prior art date: 2002-04-19

Application number

DK03723620T

Other languages

Danish (da)

English (en)

Inventor

Sinan Tas

Oktay Avci

Original Assignee

Sinan Tas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-19

Filing date

2003-03-17

Publication date

2006-03-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29247069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1496895(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-04-19 Priority claimed from PCT/TR2002/000017 external-priority patent/WO2002078704A1/en

2003-03-17 Application filed by Sinan Tas filed Critical Sinan Tas

2006-03-27 Application granted granted Critical

2006-03-27 Publication of DK1496895T3 publication Critical patent/DK1496895T3/da

Links

QASFUMOKHFSJGL-LAFRSMQTSA-N Cyclopamine Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H](CC2=C3C)[C@@H]1[C@@H]2CC[C@@]13O[C@@H]2C[C@H](C)CN[C@H]2[C@H]1C QASFUMOKHFSJGL-LAFRSMQTSA-N 0.000 title abstract 5
QASFUMOKHFSJGL-UHFFFAOYSA-N cyclopamine Natural products C1C=C2CC(O)CCC2(C)C(CC2=C3C)C1C2CCC13OC2CC(C)CNC2C1C QASFUMOKHFSJGL-UHFFFAOYSA-N 0.000 title abstract 5
201000004681 Psoriasis Diseases 0.000 title abstract 2
208000017520 skin disease Diseases 0.000 title 1
239000003246 corticosteroid Substances 0.000 abstract 3
230000003902 lesion Effects 0.000 abstract 2
230000001185 psoriatic effect Effects 0.000 abstract 2
210000003491 skin Anatomy 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
229930013930 alkaloid Natural products 0.000 abstract 1
150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
230000024245 cell differentiation Effects 0.000 abstract 1
230000008034 disappearance Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
210000002615 epidermis Anatomy 0.000 abstract 1
210000004969 inflammatory cell Anatomy 0.000 abstract 1
210000004698 lymphocyte Anatomy 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
238000002203 pretreatment Methods 0.000 abstract 1
231100000444 skin lesion Toxicity 0.000 abstract 1
206010040882 skin lesion Diseases 0.000 abstract 1
230000003637 steroidlike Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Birds (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK03723620T 2002-04-19 2003-03-17 Anvendelse af cyclopamin til behandling af psoriasis og andre hudlidelser DK1496895T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/TR2002/000017 WO2002078704A1 (en)	2001-07-02	2002-04-19	Use of cyclopamine in the treatment of psoriasis

Publications (1)

Publication Number	Publication Date
DK1496895T3 true DK1496895T3 (da)	2006-03-27

Family

ID=29247069

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03723620T DK1496895T3 (da)	2002-04-19	2003-03-17	Anvendelse af cyclopamin til behandling af psoriasis og andre hudlidelser

Country Status (15)

Country	Link
US (6)	US7893078B2 (de)
EP (2)	EP1411938B1 (de)
JP (1)	JP2006512281A (de)
KR (4)	KR20080096605A (de)
CN (2)	CN1835748A (de)
AT (1)	ATE309802T1 (de)
AU (1)	AU2003230541B2 (de)
BR (1)	BR0309396A (de)
CA (3)	CA2452152A1 (de)
DE (1)	DE60302348T2 (de)
DK (1)	DK1496895T3 (de)
EA (1)	EA200401355A1 (de)
ES (1)	ES2253672T3 (de)
MX (1)	MXPA04010294A (de)
WO (1)	WO2003088964A1 (de)

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US20110275576A1 (en) *	2009-01-06	2011-11-10	Utah State University	Carbohydrate-Cyclopamine Conjugates as Anticancer Agents
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JP6141015B2 (ja)	2009-08-05	2017-06-07	インフィニティファーマスーティカルズ、インク．	シクロパミン類似体の酵素によるアミノ基転移
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EP2911691B1 (de)	2012-10-23	2018-10-10	OncoMed Pharmaceuticals, Inc.	Verfahren zur behandlung von neuroendokrinen tumoren mit wnt-pad-bindemitteln
JP2016510411A (ja)	2013-02-04	2016-04-07	オンコメッドファーマシューティカルズインコーポレイテッド	Ｗｎｔ経路インヒビターによる処置の方法およびモニタリング
US9168300B2 (en)	2013-03-14	2015-10-27	Oncomed Pharmaceuticals, Inc.	MET-binding agents and uses thereof
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2002
- 2002-04-19 EP EP02736467A patent/EP1411938B1/de not_active Expired - Lifetime
- 2002-04-19 CA CA002452152A patent/CA2452152A1/en not_active Abandoned
2003
- 2003-03-17 KR KR1020087024138A patent/KR20080096605A/ko not_active Ceased
- 2003-03-17 CN CNA038087847A patent/CN1835748A/zh active Pending
- 2003-03-17 AU AU2003230541A patent/AU2003230541B2/en not_active Ceased
- 2003-03-17 KR KR1020077025034A patent/KR20070108287A/ko not_active Ceased
- 2003-03-17 WO PCT/TR2003/000017 patent/WO2003088964A1/en not_active Ceased
- 2003-03-17 ES ES03723620T patent/ES2253672T3/es not_active Expired - Lifetime
- 2003-03-17 JP JP2003585716A patent/JP2006512281A/ja active Pending
- 2003-03-17 CA CA2481499A patent/CA2481499C/en not_active Expired - Fee Related
- 2003-03-17 CA CA2636960A patent/CA2636960C/en not_active Expired - Fee Related
- 2003-03-17 DE DE60302348T patent/DE60302348T2/de not_active Expired - Lifetime
- 2003-03-17 CN CN200910146214A patent/CN101642458A/zh active Pending
- 2003-03-17 DK DK03723620T patent/DK1496895T3/da active
- 2003-03-17 EA EA200401355A patent/EA200401355A1/ru unknown
- 2003-03-17 KR KR10-2004-7016679A patent/KR20040102117A/ko not_active Ceased
- 2003-03-17 AT AT03723620T patent/ATE309802T1/de not_active IP Right Cessation
- 2003-03-17 MX MXPA04010294A patent/MXPA04010294A/es active IP Right Grant
- 2003-03-17 BR BR0309396-4A patent/BR0309396A/pt not_active IP Right Cessation
- 2003-03-17 KR KR1020087024137A patent/KR20080094739A/ko not_active Ceased
- 2003-03-17 EP EP03723620A patent/EP1496895B1/de not_active Expired - Lifetime
- 2003-10-09 US US10/682,584 patent/US7893078B2/en not_active Expired - Fee Related
- 2003-10-09 US US10/682,662 patent/US7605167B2/en not_active Expired - Fee Related
2007
- 2007-10-18 US US11/874,631 patent/US8025893B2/en not_active Expired - Fee Related
- 2007-10-18 US US11/874,653 patent/US7629352B2/en not_active Expired - Fee Related
2009
- 2009-07-22 US US12/460,620 patent/US9757361B2/en not_active Expired - Fee Related
2011
- 2011-01-13 US US12/930,677 patent/US20110104254A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20090286822A1 (en)	2009-11-19
JP2006512281A (ja)	2006-04-13
US20040072913A1 (en)	2004-04-15
BR0309396A (pt)	2005-02-09
US9757361B2 (en)	2017-09-12
MXPA04010294A (es)	2005-05-17
DE60302348D1 (de)	2005-12-22
US20110104254A1 (en)	2011-05-05
AU2003230541A1 (en)	2003-11-03
EP1496895B1 (de)	2005-11-16
KR20040102117A (ko)	2004-12-03
KR20070108287A (ko)	2007-11-08
US20080090790A1 (en)	2008-04-17
DE60302348T2 (de)	2006-07-27
CN101642458A (zh)	2010-02-10
CA2636960C (en)	2013-12-31
WO2003088964A1 (en)	2003-10-30
US7629352B2 (en)	2009-12-08
US20100048725A2 (en)	2010-02-25
CN1835748A (zh)	2006-09-20
KR20080096605A (ko)	2008-10-30
CA2481499C (en)	2013-05-21
EA200401355A1 (ru)	2005-06-30
US7893078B2 (en)	2011-02-22
ES2253672T3 (es)	2006-06-01
EP1411938B1 (de)	2005-07-06
CA2452152A1 (en)	2002-10-10
CA2481499A1 (en)	2003-10-30
US7605167B2 (en)	2009-10-20
CA2636960A1 (en)	2003-10-30
EP1411938A1 (de)	2004-04-28
EP1496895A1 (de)	2005-01-19
US20080089915A1 (en)	2008-04-17
ATE309802T1 (de)	2005-12-15
US20040072914A1 (en)	2004-04-15
US8025893B2 (en)	2011-09-27
KR20080094739A (ko)	2008-10-23
AU2003230541B2 (en)	2006-06-29

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MXPA05013075A (es)	2006-03-17	Inhibidores de p-38 basados en heterociclo de 5 miembros.
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