ATE317262T1 - Verwendung von tetracyclinderivaten zur steigerung der interleukin-10 produktion - Google Patents

Verwendung von tetracyclinderivaten zur steigerung der interleukin-10 produktion

Info

Publication number: ATE317262T1
Authority: AT; Austria
Prior art keywords: production; interleukin; tetracycline; effective amount; administering
Prior art date: 1998-09-11

Application number

AT99948198T

Other languages

English (en)

Inventor

Lorne M Golub

Christopher T Ritchlin

Robert A Greenwald

Sally Haas-Smith

Susan A Moak

Hsi-Ming Lee

Original Assignee

Univ New York State Res Found

Univ Rochester

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-11

Filing date

1999-09-10

Publication date

2006-02-15

1999-09-10 Application filed by Univ New York State Res Found, Univ Rochester filed Critical Univ New York State Res Found

2006-02-15 Application granted granted Critical

2006-02-15 Publication of ATE317262T1 publication Critical patent/ATE317262T1/de

Links

230000031261 interleukin-10 production Effects 0.000 title abstract 3
OFVLGDICTFRJMM-WESIUVDSSA-N tetracycline Chemical class C1=CC=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O OFVLGDICTFRJMM-WESIUVDSSA-N 0.000 title 1
239000004098 Tetracycline Substances 0.000 abstract 4
229960002180 tetracycline Drugs 0.000 abstract 4
229930101283 tetracycline Natural products 0.000 abstract 4
235000019364 tetracycline Nutrition 0.000 abstract 4
238000000034 method Methods 0.000 abstract 3
241000124008 Mammalia Species 0.000 abstract 2
230000002708 enhancing effect Effects 0.000 abstract 2
-1 tetracycline compounds Chemical class 0.000 abstract 2
150000003522 tetracyclines Chemical class 0.000 abstract 2
108010002352 Interleukin-1 Proteins 0.000 abstract 1
230000000845 anti-microbial effect Effects 0.000 abstract 1
230000019171 interleukin-1 alpha production Effects 0.000 abstract 1
210000004962 mammalian cell Anatomy 0.000 abstract 1
230000006433 tumor necrosis factor production Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Physical Education & Sports Medicine (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Biomedical Technology (AREA)
Transplantation (AREA)
Biotechnology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT99948198T 1998-09-11 1999-09-10 Verwendung von tetracyclinderivaten zur steigerung der interleukin-10 produktion ATE317262T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US09/151,534 US6015804A (en)	1998-09-11	1998-09-11	Method of using tetracycline compounds to enhance interleukin-10 production

Publications (1)

Publication Number	Publication Date
ATE317262T1 true ATE317262T1 (de)	2006-02-15

Family

ID=22539191

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99948198T ATE317262T1 (de)	1998-09-11	1999-09-10	Verwendung von tetracyclinderivaten zur steigerung der interleukin-10 produktion

Country Status (14)

Country	Link
US (1)	US6015804A (de)
EP (1)	EP1119362B1 (de)
JP (3)	JP2002524521A (de)
KR (1)	KR100691654B1 (de)
AT (1)	ATE317262T1 (de)
AU (1)	AU754515B2 (de)
CA (1)	CA2339667C (de)
CY (1)	CY1107495T1 (de)
DE (1)	DE69929810T2 (de)
DK (1)	DK1119362T3 (de)
ES (1)	ES2258854T3 (de)
NZ (1)	NZ509799A (de)
PT (1)	PT1119362E (de)
WO (1)	WO2000015235A1 (de)

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US6958161B2 (en)	2002-04-12	2005-10-25	F H Faulding & Co Limited	Modified release coated drug preparation
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JP2008518025A (ja)	2004-10-25	2008-05-29	パラテックファーマシューティカルズインコーポレイテッド	４−アミノテトラサイクリンおよびその使用の方法
WO2006047756A2 (en)	2004-10-25	2006-05-04	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds
AU2006247249A1 (en) *	2005-05-16	2006-11-23	Children's Medical Center Corporation	Method of treating Lymphangioleiomyomatosis (LAM)
US8722650B1 (en)	2005-06-24	2014-05-13	Medicis Pharmaceutical Corporation	Extended-release minocycline dosage forms
US7919483B2 (en) *	2005-06-24	2011-04-05	Medicis Pharmaceutical Corporation	Method for the treatment of acne
US9192615B2 (en)	2008-08-06	2015-11-24	Medicis Pharmaceutical Corporation	Method for the treatment of acne and certain dosage forms thereof
US20080242642A1 (en)	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
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PL2120963T3 (pl)	2006-12-21	2019-05-31	Paratek Pharm Innc	Podstawione związki tetracyklinowe do leczenia zaburzeń zapalnych skóry
IL270446B2 (en) *	2006-12-21	2023-10-01	Paratek Pharm Innc	A tetracycline compound, a pharmaceutical preparation containing the tetracycline compound, and the tetracycline compound or the pharmaceutical preparation for the treatment of the tetracycline-responsive condition
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TWI585071B (zh)	2008-05-19	2017-06-01	派洛泰克藥物股份有限公司	四環素化合物之甲苯磺酸鹽及同素異形體
HUE026562T2 (hu)	2008-08-08	2016-06-28	Tetraphase Pharmaceuticals Inc	C7-fluor-helyettesített tetraciklin vegyületek
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1998
- 1998-09-11 US US09/151,534 patent/US6015804A/en not_active Expired - Lifetime
1999
- 1999-09-10 AT AT99948198T patent/ATE317262T1/de active
- 1999-09-10 ES ES99948198T patent/ES2258854T3/es not_active Expired - Lifetime
- 1999-09-10 PT PT99948198T patent/PT1119362E/pt unknown
- 1999-09-10 WO PCT/US1999/020972 patent/WO2000015235A1/en not_active Ceased
- 1999-09-10 NZ NZ509799A patent/NZ509799A/en not_active IP Right Cessation
- 1999-09-10 EP EP99948198A patent/EP1119362B1/de not_active Expired - Lifetime
- 1999-09-10 AU AU61426/99A patent/AU754515B2/en not_active Ceased
- 1999-09-10 DK DK99948198T patent/DK1119362T3/da active
- 1999-09-10 DE DE69929810T patent/DE69929810T2/de not_active Expired - Lifetime
- 1999-09-10 JP JP2000569819A patent/JP2002524521A/ja active Pending
- 1999-09-10 CA CA2339667A patent/CA2339667C/en not_active Expired - Fee Related
- 1999-09-10 KR KR1020017002727A patent/KR100691654B1/ko not_active Expired - Fee Related
2006
- 2006-04-07 CY CY20061100490T patent/CY1107495T1/el unknown
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EP1119362A1 (de)	2001-08-01
NZ509799A (en)	2003-08-29
JP2002524521A (ja)	2002-08-06
AU6142699A (en)	2000-04-03
JP2010053146A (ja)	2010-03-11
CA2339667A1 (en)	2000-03-23
CY1107495T1 (el)	2013-03-13
DK1119362T3 (da)	2006-06-12
DE69929810T2 (de)	2006-11-02
KR20010074919A (ko)	2001-08-09
CA2339667C (en)	2010-05-18
WO2000015235A1 (en)	2000-03-23
DE69929810D1 (de)	2006-04-20
US6015804A (en)	2000-01-18
KR100691654B1 (ko)	2007-03-09
EP1119362A4 (de)	2003-03-12
AU754515B2 (en)	2002-11-21
JP4929341B2 (ja)	2012-05-09
PT1119362E (pt)	2006-06-30
JP2011148838A (ja)	2011-08-04
EP1119362B1 (de)	2006-02-08
ES2258854T3 (es)	2006-09-01

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