ATE344050T1 - Verwendung von tcf-ii zur behandlung von durch krebs verursachtem gewichtsverlust, anaemie und tnf-erhöhung - Google Patents

Verwendung von tcf-ii zur behandlung von durch krebs verursachtem gewichtsverlust, anaemie und tnf-erhöhung

Info

Publication number
ATE344050T1
ATE344050T1 AT98907159T AT98907159T ATE344050T1 AT E344050 T1 ATE344050 T1 AT E344050T1 AT 98907159 T AT98907159 T AT 98907159T AT 98907159 T AT98907159 T AT 98907159T AT E344050 T1 ATE344050 T1 AT E344050T1
Authority
AT
Austria
Prior art keywords
tcf
cancer
anaemia
tnf
elevation
Prior art date
Application number
AT98907159T
Other languages
English (en)
Inventor
Masamichi Kojiro
Hirohisa Yano
Akihiro Iemura
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE344050T1 publication Critical patent/ATE344050T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98907159T 1997-03-14 1998-03-11 Verwendung von tcf-ii zur behandlung von durch krebs verursachtem gewichtsverlust, anaemie und tnf-erhöhung ATE344050T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8216297 1997-03-14

Publications (1)

Publication Number Publication Date
ATE344050T1 true ATE344050T1 (de) 2006-11-15

Family

ID=13766743

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98907159T ATE344050T1 (de) 1997-03-14 1998-03-11 Verwendung von tcf-ii zur behandlung von durch krebs verursachtem gewichtsverlust, anaemie und tnf-erhöhung

Country Status (10)

Country Link
US (4) US20020041863A1 (de)
EP (1) EP0950416B1 (de)
AT (1) ATE344050T1 (de)
AU (1) AU734766B2 (de)
CA (1) CA2253629A1 (de)
DE (1) DE69836315T2 (de)
DK (1) DK0950416T3 (de)
ES (1) ES2274567T3 (de)
WO (1) WO1998041230A1 (de)
ZA (1) ZA982068B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4006058B2 (ja) 1997-03-11 2007-11-14 第一三共株式会社 多臓器不全予防及び／又は治療剤
AU734766B2 (en) 1997-03-14 2001-06-21 Atlas Pharmaceuticals Inc. Agent for preventing and/or treating cachexia
JPH1129493A (ja) * 1997-07-14 1999-02-02 Snow Brand Milk Prod Co Ltd 放射線障害予防及び／又は治療剤
AU2008216906A1 (en) * 2007-02-14 2008-08-21 Karolinska Innovations Ab Compositions for increasing body weight, use and methods
CN101951921A (zh) * 2007-09-17 2011-01-19 比奥尼里斯有限责任公司 用于治疗恶病质的方法和手段
EP2221043A1 (de) 2009-02-21 2010-08-25 Bayer MaterialScience AG Haarfestiger-Zusammensetzung
TW201333870A (zh) 2011-12-21 2013-08-16 艾登工具股份有限公司 決定病人胰島素療法的系統及方法
AU2020208472B2 (en) * 2019-01-17 2025-03-27 Fibrobiologics, Inc. Fibroblasts and microvesicles thereof for reduction of toxicity associated with cancer immunotherapy

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US587311A (en) * 1897-08-03 Regulating admission of currents to motors
US604184A (en) * 1898-05-17 Oil-can
US950416A (en) * 1910-02-22 Albert Sutton Wheel-tire.
US539590A (en) * 1895-05-21 passoni
US462277A (en) * 1891-11-03 Or reducing mill
US498680A (en) * 1893-05-30 Boat for transporting railroad-cars
US604185A (en) * 1898-05-17 Submarine boat
US653211A (en) * 1900-04-03 1900-07-10 John H Calkins Box for spool goods.
US757994A (en) * 1903-04-09 1904-04-19 Oliver Chilled Plow Works Sulky lister-plow.
US914829A (en) * 1908-08-26 1909-03-09 Albert O Hanson Can-opener.
US2116192A (en) * 1936-03-26 1938-05-03 Draminsky Per Elastic coupling
US2100720A (en) * 1937-01-11 1937-11-30 Shaw Walker Co Letter tray
US3904753A (en) 1970-02-20 1975-09-09 Research Corp Clinically active bovine growth hormone fraction
US4076701A (en) 1975-07-29 1978-02-28 Immunology Research Foundation, Inc. Tumor complement fraction recovery method and product
US4490549A (en) 1977-04-19 1984-12-25 The Upjohn Company Enlarged-hetero-ring prostacyclin analogs
US4481137A (en) 1982-02-26 1984-11-06 Mochida Pharmaceutical Co., Ltd. Glycoproteins and processes for their production
JPS60112718A (ja) 1983-11-21 1985-06-19 Kyorin Pharmaceut Co Ltd 抗腫瘍作用を示す蛋白性物質及びその製造方法
US4650674A (en) 1984-07-05 1987-03-17 Genentech, Inc. Synergistic cytotoxic composition
US4870163A (en) 1985-08-29 1989-09-26 New York Blood Center, Inc. Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor
US5326716A (en) * 1986-02-11 1994-07-05 Max Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Liquid phase epitaxial process for producing three-dimensional semiconductor structures by liquid phase expitaxy
US4822605A (en) 1986-02-18 1989-04-18 Exovir, Inc. Compositions and methods employing the same for the treatment of viral and cancerous skin lesions and the like
JPS6429951A (en) 1987-07-24 1989-01-31 Hitachi Ltd Storage system
JPS6468400A (en) 1987-09-09 1989-03-14 Sapporo Breweries Human tumor cytotoxic factor htcf, production thereof and antitumor agent comprising said factor as active ingredient
KR890009412A (ko) 1987-12-22 1989-08-01 마쓰시따 렌조오 종양 세포 억제 인자
JPH0296598A (ja) 1988-10-03 1990-04-09 Sapporo Breweries Ltd リンフォカイン活性化キラー細胞誘導抑制因子ｌａｋｓｆ，その製造法およびそれを有効成分とする免疫抑制剤
NZ232813A (en) 1989-03-10 1992-08-26 Snow Brand Milk Products Co Ltd Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons
US5035887A (en) 1989-09-07 1991-07-30 Institute Of Moelcular Biology, Inc. Wound healing composition of IL-1 and PDGF or IGF-1
US5648273A (en) 1989-12-27 1997-07-15 The United States Of America, As Represented By The Department Of Health And Human Services Hepatic growth factor receptor is the MET proto-oncogene
US5362716A (en) 1989-12-27 1994-11-08 The United States Of America As Represented By The Department Of Health And Human Services Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
JP2784455B2 (ja) 1990-05-09 1998-08-06 敏一 中村 肝硬変治療剤
DE69133492T2 (de) 1990-06-11 2006-08-10 Nakamura, Toshikazu Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
JP2750372B2 (ja) 1990-06-19 1998-05-13 敏一 中村 賢疾患治療剤
JP2634323B2 (ja) 1990-07-13 1997-07-23 雪印乳業株式会社 Ｔｃｆ‐▲ｉｉ▼のアミノ酸配列をコードするｄｎａを含むプラスミド，形質転換細胞及びこれを用いて生理活性物質を生産する方法
US5821223A (en) 1990-09-14 1998-10-13 The United States Of America As Represented By The Department Of Health And Human Services Method of stimulating cell growth with a novel broad spectrum human lung fibroblast-derived mitogen
HUT60282A (en) 1991-02-08 1992-08-28 Sankyo Co Process for producing new beta-amino-alpha-hydroxycarboxylic acid derivatives and pharmaceutical compositions comprising such compounds
JPH0597A (ja) 1991-06-21 1993-01-08 Snow Brand Milk Prod Co Ltd 新規抗ｔｃｆ−ｉｉモノクローナル抗体及びそれを用いるｔｃｆ−ｉｉの測定方法
JP3394982B2 (ja) 1991-11-07 2003-04-07 敏一 中村 ガン療法用副作用防止剤
ZA929869B (en) 1991-12-20 1994-06-20 Syntex Inc Hiv protease inhibitors
JP3123617B2 (ja) 1992-03-04 2001-01-15 雪印乳業株式会社 シアル酸結合を有する化合物の製造法
NO178729C (no) 1992-03-31 1996-05-22 Daiichi Seiyaku Co Terapeutisk aktive sukkerderivater
US5315000A (en) 1992-05-14 1994-05-24 Children's Hospital Medical Center Gene encoding for a L5/3 growth factor and its CDNA
JPH07508420A (ja) 1992-05-18 1995-09-21 ジェネンテク，インコーポレイテッド 肝細胞成長因子変異体
JP3619526B2 (ja) 1992-07-16 2005-02-09 第一製薬株式会社 Ｔｃｆ−ｉｉを有効成分とする肝臓疾患治療剤
DE69330960T2 (de) 1992-07-16 2002-04-11 Snow Brand Milk Products Co., Ltd. Normalisierer der blutkoagulation enthaltend tcf-ii als aktiven bestandteil
DE69334087T2 (de) 1992-07-16 2007-07-05 Daiichi Pharmaceutical Co., Ltd. Arzneimittelzusammensetzung enthaltend TCF-II
JP3380573B2 (ja) 1992-07-16 2003-02-24 第一製薬株式会社 Ｔｃｆ−ｉｉを有効成分とする蛋白合成促進剤
JPH0656692A (ja) 1992-08-10 1994-03-01 Snow Brand Milk Prod Co Ltd Ｔｃｆ−ｉｉを有効成分とする創傷治療剤
JP3697460B2 (ja) 1992-07-17 2005-09-21 敏一 中村 Ｈｇｆ含有製剤
FI933472A7 (fi) 1992-08-07 1994-02-08 Sankyo Co Peptider med foermaoga att inhibera effekten av HIV-proteas, deras framstaellning och terapeutiska anvaendning
JP3402476B2 (ja) 1992-08-24 2003-05-06 生化学工業株式会社 リポ多糖結合性タンパク質及びその製造法
EP0661993B1 (de) 1992-09-16 1997-05-07 Genentech, Inc. Schutz gegen leberschäden mit hgf
US5703047A (en) 1992-09-21 1997-12-30 Board Of Regents, The University Of Texas System Methods and treatments for corneal healing with growth factors
US5589451A (en) 1992-09-21 1996-12-31 Board Of Regents, The University Of Texas System Methods and treaments for corneal healing with hepatocyte and keratinocyte growth factors
JPH06116299A (ja) 1992-10-02 1994-04-26 Snow Brand Milk Prod Co Ltd 特定の糖鎖構造により高い生物活性を有する遺伝子組換え型ｔｃｆ
US5554653A (en) 1992-12-22 1996-09-10 Eli Lilly And Company Inhibitors of HIV protease useful for the treatment of AIDS
MX9308016A (es) 1992-12-22 1994-08-31 Lilly Co Eli Compuestos inhibidores de la proteasa del virus de la inmunodeficiencia humana, procedimiento para su preparacion y formulacion farmaceutica que los contiene.
WO1994014845A1 (en) 1992-12-28 1994-07-07 Snow Brand Milk Products Co., Ltd. Modified tcf
JP3552240B2 (ja) 1993-02-23 2004-08-11 第一製薬株式会社 高濃度ｔｃｆ製剤
JP3962097B2 (ja) 1994-03-18 2007-08-22 敏一 中村 免疫抑制剤による副作用の軽減剤
JPH07258298A (ja) 1994-03-18 1995-10-09 Snow Brand Milk Prod Co Ltd モノクローナル抗体
US5707624A (en) 1994-06-03 1998-01-13 The Regents Of The University Of Michigan Treatment of Kaposi's sarcoma by inhibition of scatter factor
JPH08176007A (ja) 1994-12-27 1996-07-09 Snow Brand Milk Prod Co Ltd 脂質代謝異常治療剤
US6399744B1 (en) 1994-12-27 2002-06-04 Daiichi Pharmaceutical Co., Ltd. TCF mutant
JPH08231418A (ja) 1995-02-24 1996-09-10 Mitsubishi Chem Corp 腸疾患治療剤
WO1996028423A1 (en) 1995-03-15 1996-09-19 Sankyo Company, Limited Dipeptide compounds having ahpba structure
EP0823256A4 (de) 1995-04-21 2000-06-21 Mitsubishi Chem Corp Mittel zur vorsorge und/oder heilmittel zur behandlung von ischämischen erkrankungen
JPH10194986A (ja) 1996-06-10 1998-07-28 Snow Brand Milk Prod Co Ltd 移植肝機能改善・再生促進剤
JP3887435B2 (ja) 1996-07-12 2007-02-28 第一製薬株式会社 スフェロイド形成促進剤
JPH1068400A (ja) 1996-08-28 1998-03-10 Tetsuo Taira 液体を押し出すボトルポンプ及びその方法と製造方法
JP4006058B2 (ja) 1997-03-11 2007-11-14 第一三共株式会社 多臓器不全予防及び／又は治療剤
AU734766B2 (en) 1997-03-14 2001-06-21 Atlas Pharmaceuticals Inc. Agent for preventing and/or treating cachexia
JP3961064B2 (ja) 1997-03-28 2007-08-15 第一製薬株式会社 腎疾患予防及び／又は治療剤
JPH1129493A (ja) 1997-07-14 1999-02-02 Snow Brand Milk Prod Co Ltd 放射線障害予防及び／又は治療剤
JPH11269091A (ja) 1998-03-19 1999-10-05 Snow Brand Milk Prod Co Ltd 敗血症予防及び／又は治療剤

Also Published As

Publication number Publication date
WO1998041230A1 (en) 1998-09-24
AU734766B2 (en) 2001-06-21
ES2274567T3 (es) 2007-05-16
US20020041863A1 (en) 2002-04-11
EP0950416A1 (de) 1999-10-20
US7115568B2 (en) 2006-10-03
US7138372B2 (en) 2006-11-21
EP0950416B1 (de) 2006-11-02
DE69836315T2 (de) 2007-05-31
CA2253629A1 (en) 1998-09-24
ZA982068B (en) 1998-09-16
US20030236191A1 (en) 2003-12-25
AU6309398A (en) 1998-10-12
DK0950416T3 (da) 2007-02-26
DE69836315D1 (de) 2006-12-14
US20030082134A1 (en) 2003-05-01
EP0950416A4 (de) 2004-06-16
US20060193827A1 (en) 2006-08-31

Similar Documents

Publication Publication Date Title
ATE499934T1 (de) Verwendung von (3.2.0) heterocyclischen verbindungen und ihren analoga zur behandlung von krebs
DE69108048D1 (de) Derivate von hydroxaminsäure und von n-hydroxyharnstoff sowie ihre verwendung.
DK0871439T3 (da) Substituerede (aryl, heteroaryl, arylmethyl eller heteroarylmethyl) hydroxamsyreforbindelser
EA200000723A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
ATE317262T1 (de) Verwendung von tetracyclinderivaten zur steigerung der interleukin-10 produktion
ID21526A (id) 4-hidroksiquinolin-3-karboksamida dan hidrazida sebagai bahan anti-virus
ATE238792T1 (de) Verwendung von makroliden zur behandlung von glaukom
DE69607615D1 (de) Neuartige metalloprotease-inhibitoren und diese enthaltende pharmazeutische zusammensetzungen
DE69930271D1 (de) Medizinische zusammensetzungen zur behandlung von augenerkrankungen
ES2090081T3 (es) Derivados de indolocarbazol, procedimientos para su obtencion y su empleo.
ATE344050T1 (de) Verwendung von tcf-ii zur behandlung von durch krebs verursachtem gewichtsverlust, anaemie und tnf-erhöhung
ATE260282T1 (de) Aromatische ester von camptothecinen und verfahren zur behandlung von krebserkrankungen
BR0213417A (pt) Compostos e composições de tetraciclicazaindóis e indolinas tendo atividade de 5-ht e seus usos
EE9900450A (et) Tetrahüdropüridoühendid, neid sisaldav ravim ja nende kasutamine
DE68924006D1 (de) Pharmazeutische Zusammensetzungen mit Eierschalenbestandteilen und ihre Herstellung und Verwendung.
DE59710517D1 (de) Adamantanaminenderivate zur bekämpfung von viren der familie bornaviridae
BR0210401A (pt) Composto, composição farmacêutica, uso de um composto e método para o tratamento de um distúrbio ou de uma doença de um corpo de animal vivo, incluindo um humano
DE60018704D1 (de) Bretyliumhaltige zusammensetzungen und kits und deren verwendung zur vorbeugung und behandlung cardiovaskulärer erkrankungen
ATE316379T1 (de) Oxyhuminsäure und ihre verwendung zur behandlung von verschiedenenen störungen
ATE517626T1 (de) Aminosubstituierte sulphonanilide und ihre derivate zur behandlung von proliferativen erkrankungen
ATE192923T1 (de) Verwendung von boswelliasäure zur behandlung von hirntumoren
ATE185274T1 (de) Therapeutisches mittel gegen drohenden abortus
DK0821969T3 (da) Medicinsk sammensætning omfattende TCF-II
ATE110714T1 (de) Derivate von hydroxaminsäure die lipoxygenase hemmen.
NO910033D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 2-hydroksy-3-fenoksypropylaminoforbindelser.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0950416

Country of ref document: EP

EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee