ATE319436T1 - Nanopartikel - Google Patents

Nanopartikel

Info

Publication number
ATE319436T1
ATE319436T1 AT01974554T AT01974554T ATE319436T1 AT E319436 T1 ATE319436 T1 AT E319436T1 AT 01974554 T AT01974554 T AT 01974554T AT 01974554 T AT01974554 T AT 01974554T AT E319436 T1 ATE319436 T1 AT E319436T1
Authority
AT
Austria
Prior art keywords
carbohydrate
nanoparticles
immobilising
therapeutics
studying
Prior art date
Application number
AT01974554T
Other languages
English (en)
Inventor
Soledad Penades
Javier Rojo
Manuel Martin-Lomas
Original Assignee
Consejo Superior Investigacion
Midatech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9901442&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE319436(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Consejo Superior Investigacion, Midatech Ltd filed Critical Consejo Superior Investigacion
Application granted granted Critical
Publication of ATE319436T1 publication Critical patent/ATE319436T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Mathematical Physics (AREA)
  • Optics & Photonics (AREA)
  • Materials Engineering (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
AT01974554T 2000-10-16 2001-10-16 Nanopartikel ATE319436T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0025414.4A GB0025414D0 (en) 2000-10-16 2000-10-16 Nanoparticles

Publications (1)

Publication Number Publication Date
ATE319436T1 true ATE319436T1 (de) 2006-03-15

Family

ID=9901442

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01974554T ATE319436T1 (de) 2000-10-16 2001-10-16 Nanopartikel
AT05026069T ATE468112T1 (de) 2000-10-16 2001-10-16 Nanopartikel

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05026069T ATE468112T1 (de) 2000-10-16 2001-10-16 Nanopartikel

Country Status (10)

Country Link
US (3) US7364919B2 (de)
EP (2) EP1671625B2 (de)
JP (2) JP4467882B2 (de)
AT (2) ATE319436T1 (de)
AU (2) AU2001294068B2 (de)
CA (1) CA2424734C (de)
DE (2) DE60142192D1 (de)
ES (2) ES2262684T3 (de)
GB (1) GB0025414D0 (de)
WO (1) WO2002032404A2 (de)

Families Citing this family (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7871597B2 (en) 1999-04-09 2011-01-18 Amag Pharmaceuticals, Inc. Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents
GB0025414D0 (en) 2000-10-16 2000-11-29 Consejo Superior Investigacion Nanoparticles
FI118061B (fi) * 2001-09-24 2007-06-15 Beanor Oy Menetelmä ja bioanturi analyysiä varten
FI115166B (fi) * 2001-12-31 2005-03-15 Biofons Oy Diagnostisia menetelmiä
CN1682237B (zh) 2002-09-20 2010-05-26 英特尔公司 用于通过使用编码探针检测生物分子的方法和仪器
US7361821B2 (en) 2002-09-20 2008-04-22 Intel Corporation Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading
US7695738B2 (en) * 2003-02-19 2010-04-13 Academia Sinica Carbohydrate encapsulated nanoparticles
WO2005010481A2 (en) * 2003-06-03 2005-02-03 The Regents Of The University Of California Preparation and use of gold glyconanoparticles
GB0313259D0 (en) * 2003-06-09 2003-07-16 Consejo Superior Investigacion Magnetic nanoparticles
WO2005044861A1 (en) * 2003-10-31 2005-05-19 Wyeth Holdings Corporation Polysaccharides of helicobacter pylori
WO2005046722A2 (en) * 2003-11-05 2005-05-26 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Carbohydrate antigen-nanoparticle conjugates and uses thereof as antimetastatic agents in treating cancer
ES2242528B1 (es) 2004-03-25 2006-12-01 Consejo Sup. Investig. Cientificas Nanoparticulas magneticas de metales nobles.
JP5398982B2 (ja) * 2004-05-24 2014-01-29 ミダテック リミテッド Ｒｎａリガンドを含むナノ粒子
GB0411537D0 (en) * 2004-05-24 2004-06-23 Midatech Ltd Nanoparticles comprising rna ligands
US20070249063A1 (en) * 2004-08-30 2007-10-25 Deshong Philip R Biosensors
AU2005291058B2 (en) * 2004-10-01 2011-09-29 Midatech Limited Nanoparticles comprising antigens and adjuvants and immunogenic structure
JP4550555B2 (ja) * 2004-11-17 2010-09-22 国立大学法人 東京医科歯科大学 量子ドット（Ｑｄｏｔ）−ナノゲル複合体の調製
JP2006182673A (ja) * 2004-12-27 2006-07-13 Kenji Yamamoto マーカー付き医薬
JP4484151B2 (ja) * 2005-03-28 2010-06-16 国立大学法人滋賀大学 ヒト血液型試薬
US8845927B2 (en) 2006-06-02 2014-09-30 Qd Vision, Inc. Functionalized nanoparticles and method
US9297092B2 (en) 2005-06-05 2016-03-29 Qd Vision, Inc. Compositions, optical component, system including an optical component, devices, and other products
EP1922419A4 (de) * 2005-06-10 2010-11-17 Life Technologies Corp Verfahren und system zur genetischen multiplex-analyse
US8252756B2 (en) 2005-06-14 2012-08-28 Northwestern University Nucleic acid functionalized nanoparticles for therapeutic applications
WO2007015105A2 (en) * 2005-08-04 2007-02-08 Thomas William Rademacher Nanoparticles comprising antibacterial ligands
GB0517077D0 (en) * 2005-08-19 2005-09-28 Isis Innovation Imaging agent
JP4670659B2 (ja) * 2006-01-25 2011-04-13 住友電気工業株式会社 蛍光標識金属粉末、ならびに該蛍光標識金属粉末を含有する異方導電膜、実装品
WO2008123844A2 (en) * 2006-02-08 2008-10-16 University Of Toledo System for detecting nanoparticles using modulated surface plasmon resonance (mspr)
US8849087B2 (en) * 2006-03-07 2014-09-30 Qd Vision, Inc. Compositions, optical component, system including an optical component, devices, and other products
TW200806315A (en) * 2006-04-26 2008-02-01 Wyeth Corp Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
US9212056B2 (en) 2006-06-02 2015-12-15 Qd Vision, Inc. Nanoparticle including multi-functional ligand and method
JP2009541259A (ja) * 2006-06-20 2009-11-26 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 糖抗原に対する特異抗体の製造方法
WO2008063662A2 (en) * 2006-11-21 2008-05-29 Black Lion Pharmaceuticals Gold (iii) chloride compositions for cancer
US9239329B2 (en) 2006-12-18 2016-01-19 Japan Science And Technology Agency Method of measuring interaction between biomaterial and sugar chain, method of evaluating biomaterial in sugar chain selectivity, method of screening biomaterial, method of patterning biomaterials, and kits for performing these methods
US20080317768A1 (en) 2007-06-21 2008-12-25 Boeing Company Bioconjugated nanoparticles
ES2320837B1 (es) 2007-07-26 2010-03-04 Consejo Superior De Investigaciones Cientificas Dispositivo de hipertermia y su utilizacion con nanoparticulas.
US8916135B2 (en) * 2007-08-22 2014-12-23 Colorado School Of Mines Lanthanide nanoparticle conjugates and uses thereof
EP2033660A1 (de) * 2007-09-05 2009-03-11 Freie Universität Berlin Funktionalisierte Nanopartikel zur Hemmung Selectin-vermittelter Zelladhäsion
GB0718843D0 (en) 2007-09-26 2007-11-07 Cancer Rec Tech Ltd Materials and methods relating to modifying the binding of antibodies
DE102007055386B4 (de) * 2007-11-20 2015-07-16 Boehringer Ingelheim Vetmedica Gmbh Verfahren zur Kalibrierung eines Sensorelements
JP5397862B2 (ja) * 2007-12-28 2014-01-22 国立大学法人滋賀医科大学 金ナノ粒子組成物、ｄｎａチップ、近赤外線吸収材、ドラッグデリバリーシステム（ｄｄｓ）用薬物保持体、着色剤、バイオセンサー、化粧品、生体内診断用組成物および治療用組成物
RU2395268C2 (ru) * 2008-01-15 2010-07-27 Евгений Петрович Гребенников Способ получения лекарственного средства
EP2123269A1 (de) * 2008-05-21 2009-11-25 Freie Universität Berlin Mit sulfatierten Aminalkoholen funktionalisierte Nanopartikel zur Hemmung selectinvermittelter Zelladhäsion
WO2010096464A1 (en) 2009-02-18 2010-08-26 Boyes Stephen G Gold/lanthanide nanoparticle conjugates and uses thereof
US20110280914A1 (en) * 2009-01-30 2011-11-17 University Of Utah Research Foundation Hydrogels crosslinked with gold nanoparticles and methods of making and using thereof
CN102481376B (zh) 2009-05-27 2016-12-21 西莱克塔生物科技公司 免疫调节剂-聚合物化合物
WO2011031298A1 (en) 2009-08-26 2011-03-17 Selecta Biosciences, Inc. Compositions that induce t cell help
JP2013524811A (ja) 2010-04-20 2013-06-20 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド ナノザイム、ナノザイムの製造方法、およびナノザイムの使用方法
US8962345B2 (en) * 2010-05-21 2015-02-24 The United States Of America As Represented By The Secretary Of Commerce Method of characterizing glycans attached to glycoproteins
US20110293723A1 (en) 2010-05-26 2011-12-01 Selecta Biosciences, Inc. Synthetic nanocarrier combination vaccines
CA2807271C (en) 2010-06-10 2018-07-31 Midatech Limited Nanoparticle film delivery systems
EP2579898B1 (de) * 2010-06-10 2019-01-09 Midatech Ltd. Peptidtragende nanopartikel
US9994443B2 (en) 2010-11-05 2018-06-12 Selecta Biosciences, Inc. Modified nicotinic compounds and related methods
EA027259B1 (ru) 2011-04-29 2017-07-31 Селекта Байосайенсиз, Инк. Наноносители, вырабатывающие иммунную толерантность, для антиген-специфического удаления т-эффекторных клеток
CN103702687A (zh) 2011-07-29 2014-04-02 西莱克塔生物科技公司 产生体液和细胞毒性t淋巴细胞（ctl）免疫应答的合成纳米载体
JP5754309B2 (ja) * 2011-09-02 2015-07-29 コニカミノルタ株式会社 表面プラズモン励起増強蛍光分光法を利用して蛍光量を測定する定量分析方法ならびにそれに用いられる定量分析用キットおよびアナライト解離抑制剤
EA201490520A1 (ru) 2011-09-07 2014-09-30 Мидатек Лимитед Противоопухолевые вакцины на основе наночастиц
ES2627507T3 (es) 2011-09-07 2017-07-28 Midatech Ltd. Composiciones de nanopartícula-péptido
US9772305B2 (en) 2011-09-15 2017-09-26 Arizona Board Of Regents On Behalf Of Arizona State University System and method for small molecule detection
GB201301991D0 (en) 2013-02-05 2013-03-20 Midatech Ltd Permeation enhanced active-carrying nanoparticles
GB201302427D0 (en) 2013-02-12 2013-03-27 Midatech Ltd Nanoparticle delivery compositions
GB201303787D0 (en) 2013-03-04 2013-04-17 Midatech Ltd Nanoparticle peptide compositions
GB201303771D0 (en) 2013-03-04 2013-04-17 Midatech Ltd Nanoparticles peptide compositions
WO2014145205A2 (en) 2013-03-15 2014-09-18 St. Jude Children's Research Hospital Methods and compositions of p27kip1 transcription modulators
KR101329646B1 (ko) 2013-05-02 2013-11-14 주식회사 지니스 표적지향증폭형 항암나노입자 및 이의 제조방법
CN105263478A (zh) 2013-05-03 2016-01-20 西莱克塔生物科技公司 用于诱导免疫耐受的具有特定药效学有效持续期之免疫抑制剂与抗原的递送
CN112933234A (zh) 2013-06-04 2021-06-11 西莱克塔生物科技公司 非免疫抑制性抗原特异性免疫治疗剂的重复施用
WO2015023715A1 (en) 2013-08-14 2015-02-19 The University Of Florida Research Foundation, Inc. Nanozymes, methods of making nanozymes, and methods of using nanozymes
JP6545177B2 (ja) 2013-09-29 2019-07-17 セント ジュード チルドレンズ リサーチ ホスピタル インコーポレイテッド 抗菌薬としてのアリール置換アミノメチルスペクチノマイシン類似体
GB201401706D0 (en) 2014-01-31 2014-03-19 Midatech Ltd Nanoparticle-insulin and insulin analogue compositions
CN106573031B (zh) 2014-04-15 2021-05-28 加利福尼亚大学董事会 双末端聚乙二醇化整合素-结合肽及其使用方法
AU2015279738A1 (en) 2014-06-25 2016-12-22 Selecta Biosciences, Inc. Methods and compositions for treatment with synthetic nanocarriers and immune checkpoint inhibitors
US9910035B1 (en) 2014-07-16 2018-03-06 Verily Life Sciences Llc Polyvalent functionalized nanoparticle-based in vivo diagnostic system
EA201790534A1 (ru) 2014-09-07 2017-07-31 Селекта Байосайенсиз, Инк. Способы и композиции для ослабления иммунных ответов против вирусного вектора для переноса, предназначенного для генной терапии
US10688125B2 (en) 2014-12-23 2020-06-23 Midatech Ltd. Nanoparticles and their use in cancer therapy
CN107529760B (zh) * 2015-05-18 2021-05-07 柿原秀己 抗菌物质、液状抗菌剂以及液状抗菌剂的制造方法
CN108137595B (zh) 2015-06-18 2021-04-20 听治疗有限责任公司 预防和治疗听力损失的方法和组合物
GB2541166A (en) 2015-07-24 2017-02-15 Midatech Ltd Nanoparticle-based liver-targeting therapy and imaging
US20170157215A1 (en) 2015-12-04 2017-06-08 Jomoco, Corp. Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
JP7417354B2 (ja) 2016-03-11 2024-01-18 セレクタ バイオサイエンシーズ インコーポレーテッド ペグ化ウリカーゼの処方物および用量
EP4014967A1 (de) 2016-04-29 2022-06-22 Icahn School of Medicine at Mount Sinai Abzielung auf das angeborene immunsystem zur induzierung von langfristiger toleranz und auflösung von makrophagenakkumulation bei atherosklerose
US20180085319A1 (en) 2016-09-27 2018-03-29 Takashi Kei Kishimoto Methods and compositions for treating cancer
JP2020504179A (ja) 2017-01-03 2020-02-06 イマージェクス ヴァクシンズ ホールディング リミテッドＥｍｅｒｇｅｘ Ｖａｃｃｉｎｅｓ Ｈｏｌｄｉｎｇ Ｌｉｍｉｔｅｄ 汎用インフルエンザワクチン組成物
KR20190104194A (ko) 2017-01-07 2019-09-06 셀렉타 바이오사이언시즈, 인크. 합성 나노담체에 커플링된 면역억제제의 패턴화된 투여
GB201701745D0 (en) 2017-02-02 2017-03-22 Midatech Ltd Nanoparticle-based liver-targeting therapy and imaging
US11426451B2 (en) 2017-03-11 2022-08-30 Selecta Biosciences, Inc. Methods and compositions related to combined treatment with antiinflammatories and synthetic nanocarriers comprising an immunosuppressant
US10543231B2 (en) 2017-05-19 2020-01-28 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
GB2563602B (en) 2017-06-19 2022-06-08 Middlesex Univ Higher Education Corporation Method and apparatus for imaging
SG11202002044WA (en) 2017-09-21 2020-04-29 Emergex Vaccines Holding Ltd MHC Class I Associated Peptides for Prevention and Treatment of Zika Virus
MX2020003838A (es) 2017-10-13 2020-08-06 Selecta Biosciences Inc Metodos y composiciones para atenuar las respuestas de inmunoglobulina m del vector de transferencia antiviral.
JP2021509400A (ja) 2018-01-06 2021-03-25 イマージェクス ヴァクシンズ ホールディング リミテッドＥｍｅｒｇｅｘ Ｖａｃｃｉｎｅｓ Ｈｏｌｄｉｎｇ Ｌｉｍｉｔｅｄ 複数のフラビウイルスの予防および治療を目的としたｍｈｃクラスｉ関連ペプチド
US20210283237A1 (en) 2018-03-29 2021-09-16 Emergex Vaccines Holding Limited Vaccine compositions
EP3773705A1 (de) 2018-03-29 2021-02-17 Emergex Vaccines Holdings Limited Impfstoffzusammensetzungen
EA202092447A1 (ru) 2018-05-18 2021-04-26 Эмерджекс Ваксинс Холдинг Лимитед Обратная пептидная вакцина
KR20210032438A (ko) 2018-07-16 2021-03-24 셀렉타 바이오사이언시즈, 인크. Otc 구축물 및 벡터의 방법 및 조성물
JP2021530571A (ja) 2018-07-16 2021-11-11 セレクタ バイオサイエンシーズ インコーポレーテッドSelecta Biosciences, Inc. Ｍｍａコンストラクトおよびベクターの方法および組成物
GB201819430D0 (en) 2018-11-29 2019-01-16 Midatech Ltd Therapeutic compounds, nanoparticles and uses thereof
GB201820470D0 (en) 2018-12-14 2019-01-30 Midatech Ltd Antifolate-carrying nanoparticles and their use in medicine
GB201820471D0 (en) 2018-12-14 2019-01-30 Midatech Ltd Nanoparticle-based therapy of inflammatory disorders
WO2020223205A1 (en) 2019-04-28 2020-11-05 Selecta Biosciences, Inc. Methods for treatment of subjects with preexisting immunity to viral transfer vectors
CA3141863A1 (en) 2019-05-28 2020-12-03 Selecta Biosciences, Inc. Methods and compositions for attenuated anti-viral transfer vector immune response
CN114207440A (zh) 2019-06-04 2022-03-18 西莱克塔生物科技公司 聚乙二醇化尿酸酶的制剂和剂量
US11890299B2 (en) 2019-06-27 2024-02-06 Hologic, Inc. Ablation agent and methods of use
EP4048269A1 (de) 2019-10-21 2022-08-31 Selecta Biosciences, Inc. Verfahren und zusammensetzungen zum behandeln von lebererkrankungen und -störungen
CN110755640B (zh) * 2019-10-21 2022-06-10 浙江师范大学 一种金铂复合纳米诊疗剂的制备方法及应用
CN118384281A (zh) 2019-11-08 2024-07-26 西莱克塔生物科技公司 聚乙二醇化尿酸酶的制剂和剂量
US20230061438A1 (en) 2019-12-18 2023-03-02 Roche Sequencing Solutions, Inc. Methods of sequencing by synthesis using a consecutive labeling scheme
MX2022010568A (es) 2020-02-26 2022-11-30 Selecta Biosciences Inc Métodos y composiciones que usan nanoportadores sintéticos que comprenden inmunosupresor.
CA3180166A1 (en) 2020-04-14 2021-10-21 Selecta Biosciences, Inc. Methods and compositions for inducing autophagy
GB202008250D0 (en) 2020-06-02 2020-07-15 Emergex Vaccines Holding Ltd Diagnosis, prevention and treatment of coronavirus infection
CN111590087B (zh) * 2020-06-04 2023-04-18 安徽医科大学 荧光金纳米簇的制备方法、制得的荧光金纳米簇及其应用
MX2023005224A (es) 2020-11-04 2023-07-18 Selecta Biosciences Inc Composiciones para reducir las respuestas inmunes contra inmunoglobulina proteasas.
CA3207247A1 (en) 2021-01-05 2022-07-14 Selecta Biosciences, Inc. Viral vector dosing protocols
EP4294435A1 (de) 2021-02-16 2023-12-27 Emergex Vaccines Holding Limited Reverse peptide aus coronavirus für immunogene zwecke
CN113059177A (zh) * 2021-03-05 2021-07-02 江苏师范大学 一种金/银/金核壳结构的纳米粒子及其合成方法
CN118459539B (zh) 2021-03-19 2026-01-06 生物治疗探索股份有限公司 用于调节训练免疫的化合物及其使用方法
JP2024514577A (ja) 2021-04-09 2024-04-02 セレクタ バイオサイエンシーズ インコーポレーテッド 免疫寛容を増強するために高親和性ｉｌ－２受容体アゴニストと組み合わせて免疫抑制剤を含む合成ナノキャリア
US20240269264A1 (en) 2021-06-02 2024-08-15 Emergex Vaccines Holding Limited Human coronavirus 229e derived peptides
CN113500199B (zh) * 2021-06-10 2022-11-08 浙江大学 一种基于金铂双金属活性氧自生成纳米材料的制备方法及其产品和应用
WO2023064350A1 (en) 2021-10-12 2023-04-20 Selecta Biosciences, Inc. Viral vector dosing protocols
US20230141563A1 (en) 2021-10-12 2023-05-11 Selecta Biosciences, Inc. Methods and compositions for attenuating anti-viral transfer vector igm responses
WO2023064887A1 (en) 2021-10-15 2023-04-20 The Board Of Trustees Of The University Of Illinois Mechanochemical dynamic therapy for focal cancer treatment
CA3237037A1 (en) 2021-11-14 2023-05-19 Cartesian Therapeutics, Inc. Multiple dosing with viral vectors
WO2023133319A1 (en) 2022-01-10 2023-07-13 Selecta Biosciences, Inc. High affinity il-2 receptor agonists and synthetic nanocarrier dose sparing
US20230357437A1 (en) 2022-03-09 2023-11-09 Selecta Biosciences, Inc. Immunosuppressants in combination with anti-igm agents and related dosing
WO2023172628A1 (en) 2022-03-09 2023-09-14 Selecta Biosciences, Inc. Immunosuppressant in combination with high affinity il-2 receptor agonists and related dosing
WO2023183568A1 (en) 2022-03-25 2023-09-28 Selecta Biosciences, Inc. Synthetic nanocarriers comprising an immunosuppressant in combination with high affinity il-2 receptor agonists and anti-igm agents
US20230381277A1 (en) 2022-04-08 2023-11-30 Selecta Biosciences, Inc. High affinity il-2 receptor agonists and immunosuppressants to enhance immune tolerance
US20240148841A1 (en) 2022-08-11 2024-05-09 Selecta Biosciences Inc. Compositions and methods related to immunoglobulin proteases and fusions thereof
WO2024107889A1 (en) 2022-11-15 2024-05-23 Selecta Biosciences, Inc. Compositions and methods for treating primary biliary cholangitis
WO2024229350A1 (en) 2023-05-03 2024-11-07 Cartesian Therapeutics, Inc. Immunosuppressant in combination with high affinity il-2 receptor agonists for diabetes
WO2024229380A1 (en) 2023-05-03 2024-11-07 Cartesian Therapeutics, Inc. Immunosuppressant in combination with high affinity il-2 receptor agonists in autoimmune liver diseases
WO2024229370A1 (en) 2023-05-03 2024-11-07 Cartesian Therapeutics, Inc. Compositions and methods for treating gvhd
WO2024229432A1 (en) 2023-05-03 2024-11-07 Cartesian Therapeutics, Inc. Synthetic nanocarriers comprising an immunosuppressant in combination with high affinity il-2 receptor agonists to enhance immune tolerance

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807532A (nl) * 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
FI830611A7 (fi) 1981-07-02 1983-02-24 Unilever Nv Painelaatikko.
WO1983001738A1 (en) * 1981-11-12 1983-05-26 SCHRÖDER, Ulf Intravascularly administrable, magnetically responsive nanosphere or manoparticle, a process for the production thereof, and the use thereof
SE8704157L (sv) * 1987-10-26 1989-04-27 Carbomatrix Ab C O Ulf Schroed Superparamagnetiska partiklar och foerfarande foer framstaellning daerav samt anvaendning
US5178882A (en) * 1990-06-22 1993-01-12 The Regents Of The University Of California Viral decoy vaccine
US5248772A (en) 1992-01-29 1993-09-28 Coulter Corporation Formation of colloidal metal dispersions using aminodextrans as reductants and protective agents
ATE179185T1 (de) 1992-08-05 1999-05-15 Meito Sangyo Kk Verbundmaterial mit kleinem durchmesser, welches ein wasserlösliches carboxylpolysaccharid und magnetisches eisenoxid enthaltet
WO1995031220A1 (en) * 1994-05-12 1995-11-23 Otsuka Pharmaceutical Co., Ltd. Contrast medium for magnetic resonance imaging
FR2777193B1 (fr) 1998-04-14 2001-06-08 Coletica Particule a groupement hydroxamique chelatante d'ions metalliques et leur utilisation en cosmetique ou en pharmacie
WO1999061911A2 (en) * 1998-04-20 1999-12-02 University Of North Carolina At Chapel Hill Nanometer particles containing a reactive monolayer
AU2001255203A1 (en) 2000-03-28 2001-10-08 Nanosphere Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
GB0025414D0 (en) 2000-10-16 2000-11-29 Consejo Superior Investigacion Nanoparticles

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