ATE323099T1 - Verfahren zur herstellung von sterol- und stanol- estern - Google Patents

Verfahren zur herstellung von sterol- und stanol- estern

Info

Publication number: ATE323099T1
Authority: AT; Austria
Prior art keywords: esters; stano; sterol; producing sterol; provides
Prior art date: 1998-08-25

Application number

AT99300486T

Other languages

English (en)

Inventor

John D Higgins

Original Assignee

Mcneil Ppc Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-25

Filing date

1999-01-22

Publication date

2006-04-15

1998-08-25 Priority claimed from US09/139,460 external-priority patent/US5892068A/en

1999-01-22 Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc

2006-04-15 Application granted granted Critical

2006-04-15 Publication of ATE323099T1 publication Critical patent/ATE323099T1/de

Links

229930182558 Sterol Natural products 0.000 title abstract 2
150000003432 sterols Chemical class 0.000 title abstract 2
235000003702 sterols Nutrition 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
230000032050 esterification Effects 0.000 abstract 1
238000005886 esterification reaction Methods 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
235000013305 food Nutrition 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
238000011031 large-scale manufacturing process Methods 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Steroid Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT99300486T 1998-08-25 1999-01-22 Verfahren zur herstellung von sterol- und stanol- estern ATE323099T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/139,460 US5892068A (en)	1998-08-25	1998-08-25	Preparation of sterol and stanol-esters
US09/211,978 US6147236A (en)	1998-08-25	1998-12-15	Preparation of sterol and stanol-esters

Publications (1)

Publication Number	Publication Date
ATE323099T1 true ATE323099T1 (de)	2006-04-15

Family

ID=26837236

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99300486T ATE323099T1 (de)	1998-08-25	1999-01-22	Verfahren zur herstellung von sterol- und stanol- estern

Country Status (13)

Country	Link
US (1)	US6184397B1 (de)
EP (1)	EP0982315B1 (de)
JP (1)	JP2000072794A (de)
KR (1)	KR20000016828A (de)
CN (1)	CN1137133C (de)
AT (1)	ATE323099T1 (de)
DE (1)	DE69930798T2 (de)
DK (1)	DK0982315T3 (de)
ES (1)	ES2262290T3 (de)
NZ (1)	NZ333817A (de)
PL (1)	PL196947B1 (de)
PT (1)	PT982315E (de)
RU (2)	RU2220150C2 (de)

Families Citing this family (18)

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US6998501B1 (en)	1999-08-30	2006-02-14	Ocean Nutrition Canada Limited	Nutritional supplement for lowering serum triglyceride and cholesterol levels
AU6813700A (en) *	1999-08-30	2001-03-26	Ocean Nutrition Canada Ltd.	A nutritional supplement for lowering serum triglyceride and cholesterol levels
RU2259750C2 (ru) *	1999-11-05	2005-09-10	Райсио Бенекол Ой	Продукт на основе оливкового масла, способ приготовления продукта на основе оливкового масла (варианты) и смесь сложных эфиров
US6576285B1 (en) *	2000-11-14	2003-06-10	Sunpure Ltd.	Cholesterol lowering beverage
US20020107232A1 (en) *	2001-01-12	2002-08-08	Flickinger Brent D.	Methods for producing sterol ester-rich compositions
US6787151B2 (en) *	2001-08-10	2004-09-07	Lipton, Division Of Conopco, Inc.	Composition for lowering blood cholesterol
US20030068425A1 (en) *	2001-09-07	2003-04-10	Khare Anil Bhagwan	Steryl ester compositions
WO2004043945A1 (en) *	2002-11-12	2004-05-27	Wiley Organics, Inc.	Method for purifying and separating soy isoflavones
US20060233863A1 (en)	2003-02-10	2006-10-19	Enzymotec Ltd.	Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy
AU2005270831B2 (en)	2004-08-10	2011-08-25	Enzymotec Ltd.	Mixture of phytosterol ester(s) and 1, 3-diglyceride(s) for use in the treatment of medical conditions
CN100334103C (zh) *	2005-09-20	2007-08-29	南京工业大学	一种从植物油沥青中提取植物甾醇乙酸酯的方法
US20080015374A1 (en) *	2006-07-11	2008-01-17	Wiley Organics, Inc.	Method for the synthesis and isolation of phytosterol esters
CN103923148A (zh) *	2010-03-12	2014-07-16	江苏春之谷生物制品有限公司	一种脂肪酸植物甾醇酯制备方法
CN102190700B (zh) *	2010-03-12	2014-05-07	江苏春之谷生物制品有限公司	一种脂肪酸植物甾醇酯制备方法
CN102321138A (zh) *	2011-06-01	2012-01-18	江南大学	一种脂肪酸植物甾醇酯的新型制备方法
CN104177467B (zh) *	2014-08-07	2016-09-07	杭州余杭博士达油脂有限公司	一种植物甾醇酯的高效合成及分离方法
EP3673751A1 (de)	2016-08-22	2020-07-01	Verbio Vereinigte Bioenergie AG	Rapsölstämmige phytosterol-phytostanolzusammensetzung
CN111848715A (zh) *	2020-09-07	2020-10-30	广州善合化工有限公司	一种植物甾醇异硬脂酸酯的制备方法和应用

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JPS444974B1 (de)	1965-08-01	1969-02-28
GB1141690A (en) *	1966-12-29	1969-01-29	Wolf Ltd Victor	Cis-trans isomerisation of unsaturated fatty acids or their esters
SU574450A1 (ru) *	1976-06-04	1977-09-30	Ленинградский химико-фармацевтический институт	3,6-Диформиат ситостан-3 ,5 ,6 ,триола, про вл ющий гиполипидемическое действие
JPS5923320B2 (ja) *	1979-10-31	1984-06-01	花王株式会社	分岐脂肪酸コレステリルエステル
US4393044A (en) *	1980-05-29	1983-07-12	The Nisshin Oil Mills Limited	Steroid ester, and cosmetics and ointments containing the same
JPS5745199A (en)	1980-09-01	1982-03-13	Nisshin Oil Mills Ltd:The	Esterification product and cosmetic or external use preparation containing the same
GB8329316D0 (en) *	1983-11-03	1983-12-07	Inst Penyelidikan Minyak Kelap	Esterification of carboxylic acids
FR2647805A1 (fr) *	1989-06-06	1990-12-07	Bugat Maurice	Procede de fabrication d'esters d'acides gras, produits isoles correspondants et compositions a usage humain ou veterinaire les contenant
CA2102112C (en) *	1991-05-03	2010-04-13	Tatu Miettinen	A substance for lowering high cholesterol level in serum and a method for preparing the same
JP3527754B2 (ja) *	1992-04-27	2004-05-17	日本精化株式会社	ラノリン脂肪酸類の分離法及びそれらを用いた化粧料及び外用薬
US5554646A (en) *	1992-04-29	1996-09-10	Wisconsin Alumni Research Foundation	Method for reducing body fat in animals
GB9300125D0 (en) *	1993-01-06	1993-03-03	Scotia Holdings Plc	Compositions containing esters of unsaturated fatty acids
WO1995000158A1 (en)	1993-06-25	1995-01-05	Bio-Sphere Technology	Dietary supplement incorporating beta-sitosterol and pectin
US5917068A (en)	1995-12-29	1999-06-29	Eastman Chemical Company	Polyunsaturated fatty acid and fatty acid ester mixtures free of sterols and phosphorus compounds
US6200624B1 (en)	1996-01-26	2001-03-13	Abbott Laboratories	Enteral formula or nutritional supplement containing arachidonic and docosahexaenoic acids
WO1998001126A2 (en) *	1996-07-05	1998-01-15	Unilever N.V.	Method of manufacturing a sterol ester mixture
UA69378C2 (uk) *	1996-11-04	2004-09-15	Райзіо Бенекол Лтд.	Текстуруюча композиція, текстуруючий агент, харчовий продукт, жирові суміші та способи їх одержання
DE69827330T2 (de)	1997-08-22	2006-02-02	Unilever N.V.	Stanolester enthaltende Zusammensetzung
EP0911385B1 (de)	1997-08-22	2003-10-15	Unilever N.V.	Stanolester enthaltende Zusammensetzungen
EP0897970B1 (de)	1997-08-22	2004-09-29	Unilever N.V.	Verfahren zur Herstellung von Stanolestern
US6394230B1 (en)	1997-12-16	2002-05-28	Cognis Corporation	Sterol esters as food additives
AU2660099A (en)	1998-02-06	1999-08-23	Medical Isotopes Inc.	Readily absorbable phytosterols to treat hypercholesterrolemia
FI109327B (fi)	1998-02-27	2002-07-15	Spice Sciences Oy	Menetelmä seerumin kokonais- ja LDL-kolestrolipitoisuutta alentavan beta-sitosterolin rasvamaisen seoksen valmistamiseksi
US6025348A (en)	1998-04-30	2000-02-15	Kao Corporation	Oil and fat composition containing phytosterol
US5892068A (en) *	1998-08-25	1999-04-06	Mcneil-Ppc, Inc.	Preparation of sterol and stanol-esters

1999
- 1999-01-19 NZ NZ333817A patent/NZ333817A/xx unknown
- 1999-01-20 CN CNB991008820A patent/CN1137133C/zh not_active Expired - Fee Related
- 1999-01-22 ES ES99300486T patent/ES2262290T3/es not_active Expired - Lifetime
- 1999-01-22 RU RU99101858/04A patent/RU2220150C2/ru not_active IP Right Cessation
- 1999-01-22 PT PT99300486T patent/PT982315E/pt unknown
- 1999-01-22 EP EP99300486A patent/EP0982315B1/de not_active Expired - Lifetime
- 1999-01-22 DK DK99300486T patent/DK0982315T3/da active
- 1999-01-22 AT AT99300486T patent/ATE323099T1/de active
- 1999-01-22 DE DE69930798T patent/DE69930798T2/de not_active Expired - Lifetime
- 1999-01-28 JP JP11020742A patent/JP2000072794A/ja active Pending
- 1999-02-02 PL PL331161A patent/PL196947B1/pl unknown
- 1999-02-04 KR KR1019990003727A patent/KR20000016828A/ko not_active Ceased
- 1999-06-21 US US09/336,773 patent/US6184397B1/en not_active Expired - Lifetime
- 1999-08-24 RU RU99118509/04A patent/RU2230750C2/ru not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20000016828A (ko)	2000-03-25
DE69930798D1 (de)	2006-05-24
US6184397B1 (en)	2001-02-06
RU2230750C2 (ru)	2004-06-20
ES2262290T3 (es)	2006-11-16
EP0982315B1 (de)	2006-04-12
NZ333817A (en)	2000-09-29
PL331161A1 (en)	2000-02-28
CN1245810A (zh)	2000-03-01
EP0982315A2 (de)	2000-03-01
DE69930798T2 (de)	2006-10-19
CN1137133C (zh)	2004-02-04
PT982315E (pt)	2006-07-31
RU2220150C2 (ru)	2003-12-27
JP2000072794A (ja)	2000-03-07
PL196947B1 (pl)	2008-02-29
EP0982315A3 (de)	2001-09-26
DK0982315T3 (da)	2006-06-19

Legal Events

Date

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Title

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2006-09-15

UEP

Publication of translation of european patent specification

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Publication	Publication Date	Title
ATE323099T1 (de)	2006-04-15	Verfahren zur herstellung von sterol- und stanol- estern
EP1067135A3 (de)	2002-11-27	Verfahren zur Herstellung von Sterol- und Stanol- Estern
BR9900280A (pt)	2000-05-02	Preparação de ésteres de esterol e estanol.
ATE178061T1 (de)	1999-04-15	Verfahren zur gewinnung von tocopherolen und sterolen aus natürlichen quellen
ATE217618T1 (de)	2002-06-15	Verfahren zur herstellung von glycidylestern verzweigter carbonsäuren
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