ATE327237T1 - Imidazol derivate, ihre herstellung und ihre verwendung - Google Patents

Imidazol derivate, ihre herstellung und ihre verwendung

Info

Publication number
ATE327237T1
ATE327237T1 AT01982800T AT01982800T ATE327237T1 AT E327237 T1 ATE327237 T1 AT E327237T1 AT 01982800 T AT01982800 T AT 01982800T AT 01982800 T AT01982800 T AT 01982800T AT E327237 T1 ATE327237 T1 AT E327237T1
Authority
AT
Austria
Prior art keywords
production
imidazole derivatives
imidazole
derivatives
Prior art date
Application number
AT01982800T
Other languages
English (en)
Inventor
Akihiro Tasaka
Takenori Hitaka
Nobuyuki Matsunaga
Masami Kusaka
Mari Adachi
Isao Aoki
Akio Ojida
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE327237T1 publication Critical patent/ATE327237T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicinal Preparation (AREA)
AT01982800T 2000-11-17 2001-11-16 Imidazol derivate, ihre herstellung und ihre verwendung ATE327237T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000351780 2000-11-17
JP2001247618 2001-08-17
JP2001336880 2001-11-01

Publications (1)

Publication Number Publication Date
ATE327237T1 true ATE327237T1 (de) 2006-06-15

Family

ID=27345219

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01982800T ATE327237T1 (de) 2000-11-17 2001-11-16 Imidazol derivate, ihre herstellung und ihre verwendung
AT05077705T ATE533768T1 (de) 2000-11-17 2001-11-16 Imidazol-derivate, ihre herstellung und ihre verwendung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05077705T ATE533768T1 (de) 2000-11-17 2001-11-16 Imidazol-derivate, ihre herstellung und ihre verwendung

Country Status (26)

Country Link
US (1) US7141598B2 (de)
EP (2) EP1681290B9 (de)
JP (2) JP3753971B2 (de)
KR (3) KR100809899B1 (de)
CN (3) CN1329394C (de)
AR (1) AR034854A1 (de)
AT (2) ATE327237T1 (de)
AU (3) AU1429602A (de)
BR (1) BR0115306B1 (de)
CA (1) CA2429133C (de)
CY (1) CY1105423T1 (de)
DE (1) DE60119963T2 (de)
DK (1) DK1334106T3 (de)
ES (1) ES2260303T3 (de)
HU (1) HU229408B1 (de)
IL (2) IL155624A0 (de)
MX (1) MXPA03004347A (de)
MY (1) MY134929A (de)
NO (1) NO326366B1 (de)
NZ (1) NZ526387A (de)
PE (1) PE20020596A1 (de)
PL (1) PL204934B1 (de)
PT (1) PT1334106E (de)
SI (1) SI1334106T1 (de)
TW (1) TWI306099B (de)
WO (1) WO2002040484A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1471056B1 (de) * 2002-01-10 2012-07-11 Takeda Pharmaceutical Company Limited Verfahren zur herstellung einer kondensierten imidazolverbindung, reformatskyreagens in stabiler form und verfahren zu dessen herstellung
WO2004075890A1 (ja) * 2003-02-26 2004-09-10 Takeda Pharmaceutical Company 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾ－ル誘導体の安定化方法
JP4745616B2 (ja) * 2003-02-26 2011-08-10 武田薬品工業株式会社 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾール誘導体の安定化方法
US20060177506A1 (en) * 2003-03-17 2006-08-10 Shigeo Yanai Release control compositions
JP4837895B2 (ja) * 2003-03-17 2011-12-14 武田薬品工業株式会社 放出制御組成物
WO2005111028A1 (en) * 2004-05-03 2005-11-24 Janssen Pharmaceutica N.V. Novel indole derivatives as selective androgen receptor modulators (sarms)
CN1960991A (zh) * 2004-05-28 2007-05-09 斯皮德尔实验股份公司 用作醛固酮合酶抑制剂的四氢咪唑并[1,5－a]吡啶衍生物
US8828429B2 (en) 2005-03-03 2014-09-09 Takeda Pharmaceutical Company Limited Release-control composition
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
AR056888A1 (es) * 2005-12-09 2007-10-31 Speedel Experimenta Ag Derivados de heterociclil imidazol
EP1991223B1 (de) * 2006-02-10 2010-07-14 Janssen Pharmaceutica, N.V. Neue imidazolopyrazolderivate als selektive androgen-rezeptor-modulatoren
TW200804284A (en) * 2006-03-31 2008-01-16 Speedel Experimenta Ag Process for preparing 6,7-dihydro-5H-imidazo[1,5-a]pyridin-8-one
AU2008319767B8 (en) * 2007-10-29 2014-01-09 Takeda Pharmaceutical Company Limited Pyrrolo [1,2-C] imidazole derivatives for use in the prophylaxis or treatment of cancer which is refractory to known cancer therapies
TWI665200B (zh) 2009-01-15 2019-07-11 英塞特公司 製造ｊａｋ抑制劑之方法及相關中間化合物
UY33740A (es) * 2010-11-18 2012-05-31 Takeda Pharmaceutical Método para tratar el cáncer de mama y cáncer de ovarios
WO2012133918A1 (en) 2011-04-01 2012-10-04 Takeda Pharmaceutical Company Limited Solid preparation
CA2838971C (en) 2011-06-15 2019-07-30 Takeda Pharmaceutical Company Limited Production method of imidazole derivatives

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
NZ221729A (en) 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
ZA882717B (en) 1987-04-22 1988-10-17 Merrell Dow Pharmaceuticals Inc. 17beta-(cyclopropylamino)-androst-5-eb-3beta-ol and related compounds useful as c17-20 lyase inhibitors
US5057521A (en) * 1988-10-26 1991-10-15 Ciba-Geigy Corporation Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism
US4966898A (en) 1989-08-15 1990-10-30 Merrell Dow Pharmaceuticals Inc. 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
WO1992015404A1 (en) 1991-03-01 1992-09-17 S.L. Electrostatic Technology, Inc. Powder coating method for producing circuit board laminae and the like
US5457102A (en) 1994-07-07 1995-10-10 Janssen Pharmaceutica, N.V. Pyrroloimidazolyl and imidazopyridinyl substituted 1H-benzimidazole derivatives
JPH07503242A (ja) * 1992-01-27 1995-04-06 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ アロマターゼ阻害剤としてのピロロイミダゾリルおよびイミダゾピリジニル置換１ｈ−ベンズイミダゾール誘導体
CZ287434B6 (en) 1992-03-31 2000-11-15 British Tech Group Use of steroids, substituted in position 17, steroids functioning as carcinostatics and pharmaceutical preparation containing thereof
GB9310635D0 (en) 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
EP0721943A4 (de) 1993-09-30 1996-09-04 Yamanouchi Pharma Co Ltd Azol-derivate und pharmazeutische präparate
WO1996014090A1 (en) 1994-11-07 1996-05-17 Janssen Pharmaceutica N.V. Compositions comprising carbazoles and cyclodextrins
WO1997000257A1 (en) 1995-06-14 1997-01-03 Yamanouchi Pharmaceutical Co., Ltd. Fused imidazole derivatives and medicinal composition thereof
WO1998037070A1 (en) 1997-02-21 1998-08-27 Takeda Chemical Industries, Ltd. Fused ring compounds, process for producing the same and use thereof
EP1028110B1 (de) 1997-10-02 2004-04-14 Daiichi Pharmaceutical Co., Ltd. Dihydronaphthalinderivate und verfahren zur herstellung derselben
CA2328973A1 (en) 1998-04-23 1999-10-28 Akio Ojida Naphthalene derivatives, their production and use
PE20010781A1 (es) * 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion

Also Published As

Publication number Publication date
DK1334106T3 (da) 2006-09-18
WO2002040484A2 (en) 2002-05-23
BR0115306B1 (pt) 2013-12-24
BR0115306A (pt) 2004-02-10
IL155624A (en) 2006-12-31
US20040033935A1 (en) 2004-02-19
MXPA03004347A (es) 2004-05-04
CN1680336A (zh) 2005-10-12
MY134929A (en) 2008-01-31
AU1429602A (en) 2002-05-27
CN100572363C (zh) 2009-12-23
DE60119963T2 (de) 2006-10-05
SI1334106T1 (sl) 2006-10-31
NO20032234D0 (no) 2003-05-16
CN1329394C (zh) 2007-08-01
HK1056168A1 (en) 2004-02-06
KR100809899B1 (ko) 2008-03-10
AR034854A1 (es) 2004-03-24
ATE533768T1 (de) 2011-12-15
CN1900079A (zh) 2007-01-24
AU2005225035B2 (en) 2007-02-22
WO2002040484A3 (en) 2002-09-26
EP1681290B9 (de) 2013-06-19
EP1334106B1 (de) 2006-05-24
NO20032234L (no) 2003-07-16
NZ526387A (en) 2004-02-27
NO326366B1 (no) 2008-11-17
PL362766A1 (en) 2004-11-02
HU229408B1 (hu) 2013-12-30
EP1681290B1 (de) 2011-11-16
AU2005225035A1 (en) 2005-11-10
CA2429133A1 (en) 2002-05-23
IL155624A0 (en) 2003-11-23
PE20020596A1 (es) 2002-08-13
AU2002214296B2 (en) 2005-09-29
ES2260303T3 (es) 2006-11-01
EP1681290A2 (de) 2006-07-19
CA2429133C (en) 2009-08-18
CN1474819A (zh) 2004-02-11
KR20080002929A (ko) 2008-01-04
JP3753971B2 (ja) 2006-03-08
HUP0400549A2 (hu) 2004-06-28
EP1681290A3 (de) 2006-07-26
HUP0400549A3 (en) 2004-09-28
KR20050105287A (ko) 2005-11-03
KR20030048156A (ko) 2003-06-18
PL204934B1 (pl) 2010-02-26
JP2003201282A (ja) 2003-07-18
JP2006045239A (ja) 2006-02-16
EP1334106A2 (de) 2003-08-13
CY1105423T1 (el) 2010-04-28
PT1334106E (pt) 2006-08-31
TWI306099B (en) 2009-02-11
AU2002214296C1 (en) 2006-04-13
US7141598B2 (en) 2006-11-28
DE60119963D1 (de) 2006-06-29
JP4427496B2 (ja) 2010-03-10
KR100725442B1 (ko) 2007-06-07

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