ATE331801T1 - Defektive rekombinante adenoviren mit einem inaktivierten gen iv a 2 - Google Patents

Defektive rekombinante adenoviren mit einem inaktivierten gen iv a 2

Info

Publication number: ATE331801T1
Authority: AT; Austria
Prior art keywords: defective recombinant; recombinant adenoviruses; inactivated gene; adenoviruses; gene
Prior art date: 1994-09-27

Application number

AT95932050T

Other languages

English (en)

Inventor

Cecile Orsini

Michel Perricaudet

Emmanuelle Vigne

Patrice Yeh

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-27

Filing date

1995-09-22

Publication date

2006-07-15

1995-09-22 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2006-07-15 Application granted granted Critical

2006-07-15 Publication of ATE331801T1 publication Critical patent/ATE331801T1/de

Links

230000002950 deficient Effects 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
241000701161 unidentified adenovirus Species 0.000 abstract 2
238000001415 gene therapy Methods 0.000 abstract 1
239000013603 viral vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/075—Adenoviridae
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10361—Methods of inactivation or attenuation
- C12N2710/10362—Methods of inactivation or attenuation by genetic engineering
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Plant Pathology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Immunology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT95932050T 1994-09-27 1995-09-22 Defektive rekombinante adenoviren mit einem inaktivierten gen iv a 2 ATE331801T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9411511A FR2724945B1 (fr)	1994-09-27	1994-09-27	Vecteurs viraux et utilisation en therapie genique

Publications (1)

Publication Number	Publication Date
ATE331801T1 true ATE331801T1 (de)	2006-07-15

Family

ID=9467310

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95932050T ATE331801T1 (de)	1994-09-27	1995-09-22	Defektive rekombinante adenoviren mit einem inaktivierten gen iv a 2

Country Status (18)

Country	Link
US (1)	US6200798B1 (de)
EP (1)	EP0783585B1 (de)
JP (1)	JPH10506018A (de)
KR (1)	KR100484441B1 (de)
AT (1)	ATE331801T1 (de)
AU (1)	AU712304B2 (de)
CA (1)	CA2197904A1 (de)
DE (1)	DE69535093T2 (de)
DK (1)	DK0783585T3 (de)
ES (1)	ES2268695T3 (de)
FI (1)	FI971275A7 (de)
FR (1)	FR2724945B1 (de)
IL (1)	IL115432A (de)
MX (1)	MX9701766A (de)
NO (1)	NO319055B1 (de)
PT (1)	PT783585E (de)
WO (1)	WO1996010088A1 (de)
ZA (1)	ZA958128B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1079830C (zh) *	1993-04-20	2002-02-27	索利斯治疗学公司	对受胞内传染原感染的个体进行治疗的方法和物质
JPH10510987A (ja) *	1994-12-12	1998-10-27	ジェネティックセラピー，インコーポレイテッド	改良アデノウイルスベクターおよび生産者細胞
AUPN477695A0 (en) *	1995-08-14	1995-09-07	Commonwealth Scientific And Industrial Research Organisation	Gene therapy
FR2753379B1 (fr)	1996-09-13	1998-10-30	Rhone Poulenc Rorer Sa	Methode de traitement de la sclerose laterale amyotrophique
GB9711957D0 (en) *	1997-06-09	1997-08-06	Isis Innovation	Methods and reagents for vaccination
WO1999023229A1 (en)	1997-10-30	1999-05-14	Cornell Research Foundation, Inc.	A method of inhibiting an immune response to a recombinant vector
US6328958B1 (en)	1998-08-28	2001-12-11	Duke University	Deleted adenovirus vectors and methods of making and administering the same
FR2794771B1 (fr)	1999-06-11	2001-08-10	Aventis Pharma Sa	Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
FR2799472B1 (fr)	1999-10-07	2004-07-16	Aventis Pharma Sa	Preparation d'adenovirus recombinants et de banques adenovirales
AUPR518501A0 (en)	2001-05-22	2001-06-14	Unisearch Limited	Yin yang-1
AU2003268145A1 (en) *	2002-08-22	2004-03-11	Merck And Co., Inc.	Methods for propagating adenovirus and virus produced thereby
HUE027013T2 (en)	2005-05-27	2016-10-28	Ospedale San Raffaele Srl	A gene vector containing MI-RNA

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5585362A (en) *	1989-08-22	1996-12-17	The Regents Of The University Of Michigan	Adenovirus vectors for gene therapy
FR2707664B1 (fr) *	1993-07-13	1995-09-29	Centre Nat Rech Scient	Vecteurs viraux et utilisation en thérapie génique.

1994
- 1994-09-27 FR FR9411511A patent/FR2724945B1/fr not_active Expired - Fee Related
1995
- 1995-09-22 CA CA002197904A patent/CA2197904A1/fr not_active Abandoned
- 1995-09-22 KR KR1019970701945A patent/KR100484441B1/ko not_active Expired - Fee Related
- 1995-09-22 US US08/809,476 patent/US6200798B1/en not_active Expired - Fee Related
- 1995-09-22 WO PCT/FR1995/001228 patent/WO1996010088A1/fr not_active Ceased
- 1995-09-22 DK DK95932050T patent/DK0783585T3/da active
- 1995-09-22 AU AU35250/95A patent/AU712304B2/en not_active Ceased
- 1995-09-22 PT PT95932050T patent/PT783585E/pt unknown
- 1995-09-22 MX MX9701766A patent/MX9701766A/es not_active IP Right Cessation
- 1995-09-22 FI FI971275A patent/FI971275A7/fi unknown
- 1995-09-22 ES ES95932050T patent/ES2268695T3/es not_active Expired - Lifetime
- 1995-09-22 EP EP95932050A patent/EP0783585B1/de not_active Expired - Lifetime
- 1995-09-22 DE DE69535093T patent/DE69535093T2/de not_active Expired - Fee Related
- 1995-09-22 AT AT95932050T patent/ATE331801T1/de not_active IP Right Cessation
- 1995-09-22 JP JP8511437A patent/JPH10506018A/ja not_active Ceased
- 1995-09-27 IL IL115432A patent/IL115432A/en not_active IP Right Cessation
- 1995-09-27 ZA ZA958128A patent/ZA958128B/xx unknown
1997
- 1997-03-18 NO NO19971247A patent/NO319055B1/no unknown

Also Published As

Publication number	Publication date
DK0783585T3 (da)	2006-10-23
EP0783585A1 (de)	1997-07-16
IL115432A (en)	2006-10-05
CA2197904A1 (fr)	1996-04-04
FI971275L (fi)	1997-03-26
FI971275A0 (fi)	1997-03-26
FR2724945B1 (fr)	1996-12-27
FI971275A7 (fi)	1997-03-26
FR2724945A1 (fr)	1996-03-29
ZA958128B (en)	1996-04-24
MX9701766A (es)	1997-06-28
US6200798B1 (en)	2001-03-13
AU3525095A (en)	1996-04-19
NO971247D0 (no)	1997-03-18
AU712304B2 (en)	1999-11-04
PT783585E (pt)	2006-11-30
NO971247L (no)	1997-03-18
JPH10506018A (ja)	1998-06-16
KR970706397A (ko)	1997-11-03
WO1996010088A1 (fr)	1996-04-04
IL115432A0 (en)	1996-01-31
DE69535093T2 (de)	2007-01-04
KR100484441B1 (ko)	2006-01-27
NO319055B1 (no)	2005-06-13
EP0783585B1 (de)	2006-06-28
ES2268695T3 (es)	2007-03-16
DE69535093D1 (de)	2006-08-10

Legal Events

Date

Code

Title

Description

2007-05-15

UEP

Publication of translation of european patent specification

Ref document number: 0783585

Country of ref document: EP

2008-06-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
FI971783A7 (fi)	1997-04-25	Adenoviruksia, joissa ei ole elinkykyisiä kontaminoivia partikkeleita, niiden valmistus ja käyttöjä
FI951138A7 (fi)	1995-04-13	Puuttellisia adenovirusvektoreita ja niiden käyttö geeniterapiassa
FI971613A7 (fi)	1997-04-16	Defektiivisiä adenoviruksia, jotka käsittävät terapeuttisen geenin ja immunoprotektiivisen geenin
ATE331801T1 (de)	2006-07-15	Defektive rekombinante adenoviren mit einem inaktivierten gen iv a 2
ZA942778B (en)	1995-01-09	Recombinant viruses, and their preparation and use in gene therapy.
HUP9802217A3 (en)	1999-09-28	Recombinant mva virus, and the use thereof
FR2712603B1 (fr)	1996-02-09	Virus recombinants, préparation et utilisation en thérapie génique.
DE69826661D1 (de)	2004-11-04	Antitumorale zusammenstellung von immunogene polypetiden mit veränderter zellokalisierung
CA2213343A1 (en)	1996-08-29	Chimeric adenoviral fiber protein and methods of using same
CA2127541A1 (en)	1993-07-22	Recombinant swinepox virus
BR9607583B1 (pt)	2009-12-01	plasmìdios procarióticos recombinantes.
FR2712602B1 (fr)	1996-02-09	Virus recombinants, préparation et utilisation en thérapie génique.
FR2702152B1 (fr)	1995-05-24	Virus recombinants et leur utilisation en thérapie génique.
EP0747482A3 (de)	1997-10-22	Rekombinante Proteine des Hepatitis GB Virus ihre Verwendungen
FR2717495B1 (fr)	1996-04-12	Virus recombinants, préparation et utilisation en thérapie génique.
IL112992A0 (en)	1995-06-29	Recombinant viruses, their preparation and their use in gene therapy
CA2475337A1 (en)	1998-08-06	Methods for cultivating cells and propagating viruses
FR2717823B1 (fr)	1996-04-26	Virus recombinants, préparation et utilisation en thérapie génique.
ES296560U (es)	1988-01-16	Horno industrial calentado electricamente
FR2717497B1 (fr)	1996-04-12	Virus recombinants, préparation et utilisation en thérapie génique.
GB9315259D0 (en)	1993-09-08	Recombinant viruses