DK0783585T3 - Defekte rekombinante adenovira med et inaktiveret IVa2-gen - Google Patents

Defekte rekombinante adenovira med et inaktiveret IVa2-gen

Info

Publication number: DK0783585T3
Authority: DK; Denmark
Prior art keywords: inactivated; defective recombinant; recombinant adenoviruses; iva2 gene; gene
Prior art date: 1994-09-27

Application number

DK95932050T

Other languages

English (en)

Inventor

Cecile Orsini

Patrice Yeh

Michel Perricaudet

Emmanuelle Vigne

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-27

Filing date

1995-09-22

Publication date

2006-10-23

1995-09-22 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2006-10-23 Application granted granted Critical

2006-10-23 Publication of DK0783585T3 publication Critical patent/DK0783585T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/075—Adenoviridae
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10361—Methods of inactivation or attenuation
- C12N2710/10362—Methods of inactivation or attenuation by genetic engineering
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Gastroenterology & Hepatology (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Immunology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK95932050T 1994-09-27 1995-09-22 Defekte rekombinante adenovira med et inaktiveret IVa2-gen DK0783585T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9411511A FR2724945B1 (fr)	1994-09-27	1994-09-27	Vecteurs viraux et utilisation en therapie genique

Publications (1)

Publication Number	Publication Date
DK0783585T3 true DK0783585T3 (da)	2006-10-23

Family

ID=9467310

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95932050T DK0783585T3 (da)	1994-09-27	1995-09-22	Defekte rekombinante adenovira med et inaktiveret IVa2-gen

Country Status (18)

Country	Link
US (1)	US6200798B1 (da)
EP (1)	EP0783585B1 (da)
JP (1)	JPH10506018A (da)
KR (1)	KR100484441B1 (da)
AT (1)	ATE331801T1 (da)
AU (1)	AU712304B2 (da)
CA (1)	CA2197904A1 (da)
DE (1)	DE69535093T2 (da)
DK (1)	DK0783585T3 (da)
ES (1)	ES2268695T3 (da)
FI (1)	FI971275A0 (da)
FR (1)	FR2724945B1 (da)
IL (1)	IL115432A (da)
MX (1)	MX9701766A (da)
NO (1)	NO319055B1 (da)
PT (1)	PT783585E (da)
WO (1)	WO1996010088A1 (da)
ZA (1)	ZA958128B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR960701988A (ko) *	1993-04-20	1996-03-28	윌리엄 에스. 로빈슨	세포내 감염원에 감염된 개체의 치료방법 및 치료물질(methods and materials for treatment of individuals infected with intracellular in-fectious agents)
CA2206683A1 (en) *	1994-12-12	1996-06-20	Genetic Therapy, Inc.	Improved adenoviral vectors and producer cells
AUPN477695A0 (en) *	1995-08-14	1995-09-07	Commonwealth Scientific And Industrial Research Organisation	Gene therapy
FR2753379B1 (fr)	1996-09-13	1998-10-30	Rhone Poulenc Rorer Sa	Methode de traitement de la sclerose laterale amyotrophique
GB9711957D0 (en) *	1997-06-09	1997-08-06	Isis Innovation	Methods and reagents for vaccination
AU1288099A (en)	1997-10-30	1999-05-24	Cornell Research Foundation Inc.	A method of inhibiting an immune response to a recombinant vector
CA2340276A1 (en)	1998-08-28	2000-03-09	Duke University	Adenoviruses deleted in the iva2, 100k and/or preterminal protein sequences
FR2794771B1 (fr)	1999-06-11	2001-08-10	Aventis Pharma Sa	Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
FR2799472B1 (fr) *	1999-10-07	2004-07-16	Aventis Pharma Sa	Preparation d'adenovirus recombinants et de banques adenovirales
AUPR518501A0 (en)	2001-05-22	2001-06-14	Unisearch Limited	Yin yang-1
WO2004018627A2 (en) *	2002-08-22	2004-03-04	Merck & Co., Inc.	Methods for propagating adenovirus and virus produced thereby
ES2564823T3 (es)	2005-05-27	2016-03-29	Ospedale San Raffaele S.R.L.	Vector génico que comprende miARN

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5585362A (en) *	1989-08-22	1996-12-17	The Regents Of The University Of Michigan	Adenovirus vectors for gene therapy
FR2707664B1 (fr) *	1993-07-13	1995-09-29	Centre Nat Rech Scient	Vecteurs viraux et utilisation en thérapie génique.

1994
- 1994-09-27 FR FR9411511A patent/FR2724945B1/fr not_active Expired - Fee Related
1995
- 1995-09-22 EP EP95932050A patent/EP0783585B1/fr not_active Expired - Lifetime
- 1995-09-22 AT AT95932050T patent/ATE331801T1/de not_active IP Right Cessation
- 1995-09-22 CA CA002197904A patent/CA2197904A1/fr not_active Abandoned
- 1995-09-22 DE DE69535093T patent/DE69535093T2/de not_active Expired - Fee Related
- 1995-09-22 US US08/809,476 patent/US6200798B1/en not_active Expired - Fee Related
- 1995-09-22 JP JP8511437A patent/JPH10506018A/ja not_active Ceased
- 1995-09-22 MX MX9701766A patent/MX9701766A/es not_active IP Right Cessation
- 1995-09-22 WO PCT/FR1995/001228 patent/WO1996010088A1/fr not_active Ceased
- 1995-09-22 DK DK95932050T patent/DK0783585T3/da active
- 1995-09-22 PT PT95932050T patent/PT783585E/pt unknown
- 1995-09-22 ES ES95932050T patent/ES2268695T3/es not_active Expired - Lifetime
- 1995-09-22 KR KR1019970701945A patent/KR100484441B1/ko not_active Expired - Fee Related
- 1995-09-22 AU AU35250/95A patent/AU712304B2/en not_active Ceased
- 1995-09-22 FI FI971275A patent/FI971275A0/fi unknown
- 1995-09-27 IL IL115432A patent/IL115432A/en not_active IP Right Cessation
- 1995-09-27 ZA ZA958128A patent/ZA958128B/xx unknown
1997
- 1997-03-18 NO NO19971247A patent/NO319055B1/no unknown

Also Published As

Publication number	Publication date
EP0783585A1 (fr)	1997-07-16
IL115432A0 (en)	1996-01-31
WO1996010088A1 (fr)	1996-04-04
ATE331801T1 (de)	2006-07-15
DE69535093D1 (de)	2006-08-10
JPH10506018A (ja)	1998-06-16
FI971275A7 (fi)	1997-03-26
FR2724945B1 (fr)	1996-12-27
ES2268695T3 (es)	2007-03-16
IL115432A (en)	2006-10-05
NO971247D0 (no)	1997-03-18
MX9701766A (es)	1997-06-28
AU712304B2 (en)	1999-11-04
NO319055B1 (no)	2005-06-13
CA2197904A1 (fr)	1996-04-04
AU3525095A (en)	1996-04-19
PT783585E (pt)	2006-11-30
FI971275L (fi)	1997-03-26
KR970706397A (ko)	1997-11-03
ZA958128B (en)	1996-04-24
NO971247L (no)	1997-03-18
DE69535093T2 (de)	2007-01-04
FR2724945A1 (fr)	1996-03-29
KR100484441B1 (ko)	2006-01-27
EP0783585B1 (fr)	2006-06-28
US6200798B1 (en)	2001-03-13
FI971275A0 (fi)	1997-03-26

Publication	Publication Date	Title
FI951138A7 (fi)	1995-04-13	Puuttellisia adenovirusvektoreita ja niiden käyttö geeniterapiassa
FI971783A7 (fi)	1997-04-25	Adenoviruksia, joissa ei ole elinkykyisiä kontaminoivia partikkeleita, niiden valmistus ja käyttöjä
FI971613A7 (fi)	1997-04-16	Defektiivisiä adenoviruksia, jotka käsittävät terapeuttisen geenin ja immunoprotektiivisen geenin
FR2712603B1 (fr)	1996-02-09	Virus recombinants, préparation et utilisation en thérapie génique.
ES2191663T3 (es)	2003-09-16	Virus recombinante de la viruela porcina.
ZA942778B (en)	1995-01-09	Recombinant viruses, and their preparation and use in gene therapy.
KR970706806A (ko)	1997-12-01	신규한 아데노바이러스성 벡터, 패키징 세포주, 재조합 아데노바이러스와 그 방법(novel adenoviral vectors, packagning cell lines, recombinant adenoviruses and methods)
NO20024157D0 (no)	2002-08-30	Kasein-avledete peptider og anvendelser derav i terapi
HUP9802217A3 (en)	1999-09-28	Recombinant mva virus, and the use thereof
NO971247D0 (no)	1997-03-18	Defektive, rekombinante adenoviruser med inaktivt IVa2-gen
FR2718150B1 (fr)	1996-04-26	Virus recombinants, préparation et utilisation en thérapie génique.
BR9607583B1 (pt)	2009-12-01	plasmìdios procarióticos recombinantes.
FR2712602B1 (fr)	1996-02-09	Virus recombinants, préparation et utilisation en thérapie génique.
PL375113A1 (en)	2005-11-28	Casein derived peptides and uses thereof in therapy
FR2717495B1 (fr)	1996-04-12	Virus recombinants, préparation et utilisation en thérapie génique.
MX9702078A (es)	1997-06-28	Adenovirus que comprenden dos genes terapeuticos: suicida e inmunoestimulante.
DE69726602D1 (en)	2004-01-15	Hepatitis b inhibitoren
FR2717496B1 (fr)	1996-04-12	Virus recombinants, préparation et utilisation en thérapie génique.
FR2717823B1 (fr)	1996-04-26	Virus recombinants, préparation et utilisation en thérapie génique.
FR2717497B1 (fr)	1996-04-12	Virus recombinants, préparation et utilisation en thérapie génique.
FR2718749B1 (fr)	1996-05-31	Vecteurs viraux et utilisation en thérapie génique.