ATE333898T1 - Glycerinmonolaurat und laurylacetat enthaltende mittel zur hautpenetrationsbeschleunigung - Google Patents

Glycerinmonolaurat und laurylacetat enthaltende mittel zur hautpenetrationsbeschleunigung

Info

Publication number
ATE333898T1
ATE333898T1 AT96916825T AT96916825T ATE333898T1 AT E333898 T1 ATE333898 T1 AT E333898T1 AT 96916825 T AT96916825 T AT 96916825T AT 96916825 T AT96916825 T AT 96916825T AT E333898 T1 ATE333898 T1 AT E333898T1
Authority
AT
Austria
Prior art keywords
lauryl acetate
skin penetration
agents containing
containing glycerin
penetration accelerator
Prior art date
Application number
AT96916825T
Other languages
English (en)
Inventor
Terry L Burkoth
Lina T Taskovich
Nieves Marzan Crisologo
Russell Beste
Richard D Hamlin
Robert M Gale
Eun Soo Lee
Su Il Yum
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE333898T1 publication Critical patent/ATE333898T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
AT96916825T 1995-06-07 1996-05-30 Glycerinmonolaurat und laurylacetat enthaltende mittel zur hautpenetrationsbeschleunigung ATE333898T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/481,549 US5785991A (en) 1995-06-07 1995-06-07 Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate

Publications (1)

Publication Number Publication Date
ATE333898T1 true ATE333898T1 (de) 2006-08-15

Family

ID=23912386

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96916825T ATE333898T1 (de) 1995-06-07 1996-05-30 Glycerinmonolaurat und laurylacetat enthaltende mittel zur hautpenetrationsbeschleunigung

Country Status (13)

Country Link
US (2) US5785991A (de)
EP (1) EP0835136B1 (de)
JP (1) JP3916664B2 (de)
KR (1) KR100524325B1 (de)
AT (1) ATE333898T1 (de)
AU (1) AU714809B2 (de)
BR (1) BR9608551A (de)
CA (1) CA2221096C (de)
DE (2) DE69636390T2 (de)
ES (1) ES2268707T3 (de)
GB (1) GB2305122B (de)
MX (1) MX9709492A (de)
WO (1) WO1996040259A2 (de)

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WO1996040259A3 (en) 1997-02-27
US5843468A (en) 1998-12-01
CA2221096C (en) 2008-09-30
GB9611563D0 (en) 1996-08-07
JP3916664B2 (ja) 2007-05-16
GB2305122A (en) 1997-04-02
DE19622902A1 (de) 1996-12-12
GB2305122B (en) 1999-06-16
EP0835136B1 (de) 2006-07-26
KR100524325B1 (ko) 2006-01-27
US5785991A (en) 1998-07-28
BR9608551A (pt) 1999-07-06
AU714809B2 (en) 2000-01-13
ES2268707T3 (es) 2007-03-16
AU5957296A (en) 1996-12-30
DE19622902C2 (de) 2001-05-23
MX9709492A (es) 1998-02-28
DE69636390T2 (de) 2007-09-20
JPH11512073A (ja) 1999-10-19
KR19990022571A (ko) 1999-03-25
EP0835136A2 (de) 1998-04-15
WO1996040259A2 (en) 1996-12-19
CA2221096A1 (en) 1996-12-19
DE69636390D1 (de) 2006-09-07

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