ATE335001T1 - Transkriptionsaktivator-gen für gene, die beteiligt sind an der biosynthese von cobalamin - Google Patents

Transkriptionsaktivator-gen für gene, die beteiligt sind an der biosynthese von cobalamin

Info

Publication number: ATE335001T1
Authority: AT; Austria
Prior art keywords: cobalamin; biosynthesis; genes involved; activator gene; transcription activator
Prior art date: 2002-09-27

Application number

AT03750606T

Other languages

English (en)

Inventor

Tatsuo Hoshino

Yutaka Setoguchi

Noribumi Tomiyama

Original Assignee

Dsm Ip Assets Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-27

Filing date

2003-09-23

Publication date

2006-08-15

2003-09-23 Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv

2006-08-15 Application granted granted Critical

2006-08-15 Publication of ATE335001T1 publication Critical patent/ATE335001T1/de

Links

108090000623 proteins and genes Proteins 0.000 title abstract 3
230000015572 biosynthetic process Effects 0.000 title abstract 2
239000012190 activator Substances 0.000 title 1
ASARMUCNOOHMLO-WLORSUFZSA-L cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2s)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O ASARMUCNOOHMLO-WLORSUFZSA-L 0.000 title 1
230000035897 transcription Effects 0.000 title 1
238000013518 transcription Methods 0.000 title 1
238000000034 method Methods 0.000 abstract 2
108020004511 Recombinant DNA Proteins 0.000 abstract 1
150000001867 cobalamins Chemical class 0.000 abstract 1
229940010007 cobalamins Drugs 0.000 abstract 1
FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 1
JBJSVEVEEGOEBZ-SCZZXKLOSA-K coenzyme B(3-) Chemical compound [O-]P(=O)([O-])O[C@H](C)[C@@H](C([O-])=O)NC(=O)CCCCCCS JBJSVEVEEGOEBZ-SCZZXKLOSA-K 0.000 abstract 1
108091006106 transcriptional activators Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/42—Cobalamins, i.e. vitamin B12, LLD factor

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)

AT03750606T 2002-09-27 2003-09-23 Transkriptionsaktivator-gen für gene, die beteiligt sind an der biosynthese von cobalamin ATE335001T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02021603		2002-09-27

Publications (1)

Publication Number	Publication Date
ATE335001T1 true ATE335001T1 (de)	2006-08-15

Family

ID=32049968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03750606T ATE335001T1 (de)	2002-09-27	2003-09-23	Transkriptionsaktivator-gen für gene, die beteiligt sind an der biosynthese von cobalamin

Country Status (9)

Country	Link
US (1)	US20060024796A1 (de)
EP (1)	EP1543026B1 (de)
JP (1)	JP2006516385A (de)
CN (1)	CN1681840A (de)
AT (1)	ATE335001T1 (de)
AU (1)	AU2003271044A1 (de)
BR (1)	BR0314681A (de)
DE (1)	DE60307294D1 (de)
WO (1)	WO2004031227A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2608579C (en)	2005-05-26	2019-09-10	Cytos Biotechnology Ag	Scalable fermentation process
JP5957443B2 (ja) *	2011-03-28	2016-07-27	長瀬産業株式会社	フェリチンの製造方法
CN104342390B (zh) *	2014-10-10	2017-03-15	中国科学院天津工业生物技术研究所	一种苜蓿中华根瘤菌株及其组合物与应用
CN109321614A (zh) *	2018-10-22	2019-02-12	山东泓达生物科技有限公司	一种促维生素b12发酵的组合物及其应用
CN109837320A (zh) *	2019-03-27	2019-06-04	山东泓达生物科技有限公司	一种提高脱氮假单胞杆菌产维生素b12的方法
CN110950938B (zh) *	2019-12-23	2021-09-28	中国科学院天津工业生物技术研究所	一种双组分调控系统及其在制备维生素b12中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2698879B1 (fr) *	1992-12-09	1995-01-13	Rhone Poulenc Biochimie	gellules modifiées au niveau du catabolisme de la bétaïne, préparation et utilisations, notamment pour la production de métabolites ou d'enzymes.
HUP0102820A3 (en) *	1998-06-25	2003-09-29	Dsm Ip Assets Bv	Propionibacterium vector

2003
- 2003-09-23 AU AU2003271044A patent/AU2003271044A1/en not_active Abandoned
- 2003-09-23 BR BR0314681-2A patent/BR0314681A/pt not_active Application Discontinuation
- 2003-09-23 US US10/528,674 patent/US20060024796A1/en not_active Abandoned
- 2003-09-23 CN CNA038221489A patent/CN1681840A/zh active Pending
- 2003-09-23 AT AT03750606T patent/ATE335001T1/de not_active IP Right Cessation
- 2003-09-23 WO PCT/EP2003/010572 patent/WO2004031227A1/en not_active Ceased
- 2003-09-23 JP JP2004540680A patent/JP2006516385A/ja not_active Withdrawn
- 2003-09-23 EP EP03750606A patent/EP1543026B1/de not_active Expired - Lifetime
- 2003-09-23 DE DE60307294T patent/DE60307294D1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP2006516385A (ja)	2006-07-06
CN1681840A (zh)	2005-10-12
DE60307294D1 (de)	2006-09-14
EP1543026B1 (de)	2006-08-02
EP1543026A1 (de)	2005-06-22
WO2004031227A1 (en)	2004-04-15
AU2003271044A1 (en)	2004-04-23
US20060024796A1 (en)	2006-02-02
BR0314681A (pt)	2005-08-02

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Legal Events

Date	Code	Title	Description
2007-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties