BR0314681A - Gene ativador da transcrição para genes envolvidos na sìntese da cobalamina - Google Patents
Gene ativador da transcrição para genes envolvidos na sìntese da cobalaminaInfo
- Publication number
- BR0314681A BR0314681A BR0314681-2A BR0314681A BR0314681A BR 0314681 A BR0314681 A BR 0314681A BR 0314681 A BR0314681 A BR 0314681A BR 0314681 A BR0314681 A BR 0314681A
- Authority
- BR
- Brazil
- Prior art keywords
- genes involved
- activator gene
- transcription activator
- cobalamin synthesis
- cobalamin
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 title abstract 2
- 239000012190 activator Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 230000035897 transcription Effects 0.000 title 1
- 238000013518 transcription Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 150000001867 cobalamins Chemical class 0.000 abstract 1
- 229940010007 cobalamins Drugs 0.000 abstract 1
- JBJSVEVEEGOEBZ-SCZZXKLOSA-K coenzyme B(3-) Chemical compound [O-]P(=O)([O-])O[C@H](C)[C@@H](C([O-])=O)NC(=O)CCCCCCS JBJSVEVEEGOEBZ-SCZZXKLOSA-K 0.000 abstract 1
- 108091006106 transcriptional activators Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/42—Cobalamins, i.e. vitamin B12, LLD factor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Abstract
"GENE ATIVADOR DA TRANSCRIçãO PARA GENES ENVOLVIDOS NA SìNTESE DA COBALAMINA". A presente invenção refere-se a um gene ativador da transcrição para os genes envolvidos na biossíntese da cobalamina. Mais precisamente, refere-se a um processo para a amplificação da produção de cobalaminas e, mais especificamente, da co-enzima B~ 12~ através de técnicas do DNA recombinante.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02021603 | 2002-09-27 | ||
| PCT/EP2003/010572 WO2004031227A1 (en) | 2002-09-27 | 2003-09-23 | Transcriptional activator gene for genes involved in cobalamin biosynthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0314681A true BR0314681A (pt) | 2005-08-02 |
Family
ID=32049968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0314681-2A BR0314681A (pt) | 2002-09-27 | 2003-09-23 | Gene ativador da transcrição para genes envolvidos na sìntese da cobalamina |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060024796A1 (pt) |
| EP (1) | EP1543026B1 (pt) |
| JP (1) | JP2006516385A (pt) |
| CN (1) | CN1681840A (pt) |
| AT (1) | ATE335001T1 (pt) |
| AU (1) | AU2003271044A1 (pt) |
| BR (1) | BR0314681A (pt) |
| DE (1) | DE60307294D1 (pt) |
| WO (1) | WO2004031227A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1885847B1 (en) | 2005-05-26 | 2011-07-06 | Cytos Biotechnology AG | Scalable fermentation process |
| JP5957443B2 (ja) * | 2011-03-28 | 2016-07-27 | 長瀬産業株式会社 | フェリチンの製造方法 |
| CN104342390B (zh) * | 2014-10-10 | 2017-03-15 | 中国科学院天津工业生物技术研究所 | 一种苜蓿中华根瘤菌株及其组合物与应用 |
| CN109321614A (zh) * | 2018-10-22 | 2019-02-12 | 山东泓达生物科技有限公司 | 一种促维生素b12发酵的组合物及其应用 |
| CN109837320A (zh) * | 2019-03-27 | 2019-06-04 | 山东泓达生物科技有限公司 | 一种提高脱氮假单胞杆菌产维生素b12的方法 |
| CN110950938B (zh) * | 2019-12-23 | 2021-09-28 | 中国科学院天津工业生物技术研究所 | 一种双组分调控系统及其在制备维生素b12中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2698879B1 (fr) * | 1992-12-09 | 1995-01-13 | Rhone Poulenc Biochimie | gellules modifiées au niveau du catabolisme de la bétaïne, préparation et utilisations, notamment pour la production de métabolites ou d'enzymes. |
| ID28046A (id) * | 1998-06-25 | 2001-05-03 | Dsm Nv | Vektor propionibacterium |
-
2003
- 2003-09-23 AU AU2003271044A patent/AU2003271044A1/en not_active Abandoned
- 2003-09-23 DE DE60307294T patent/DE60307294D1/de not_active Expired - Lifetime
- 2003-09-23 AT AT03750606T patent/ATE335001T1/de not_active IP Right Cessation
- 2003-09-23 US US10/528,674 patent/US20060024796A1/en not_active Abandoned
- 2003-09-23 BR BR0314681-2A patent/BR0314681A/pt not_active Application Discontinuation
- 2003-09-23 EP EP03750606A patent/EP1543026B1/en not_active Expired - Lifetime
- 2003-09-23 WO PCT/EP2003/010572 patent/WO2004031227A1/en not_active Ceased
- 2003-09-23 JP JP2004540680A patent/JP2006516385A/ja not_active Withdrawn
- 2003-09-23 CN CNA038221489A patent/CN1681840A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003271044A1 (en) | 2004-04-23 |
| EP1543026B1 (en) | 2006-08-02 |
| US20060024796A1 (en) | 2006-02-02 |
| JP2006516385A (ja) | 2006-07-06 |
| EP1543026A1 (en) | 2005-06-22 |
| DE60307294D1 (de) | 2006-09-14 |
| ATE335001T1 (de) | 2006-08-15 |
| CN1681840A (zh) | 2005-10-12 |
| WO2004031227A1 (en) | 2004-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |