ATE444377T1 - Nukleinsäurecharakterisierung - Google Patents

Nukleinsäurecharakterisierung

Info

Publication number
ATE444377T1
ATE444377T1 AT05701850T AT05701850T ATE444377T1 AT E444377 T1 ATE444377 T1 AT E444377T1 AT 05701850 T AT05701850 T AT 05701850T AT 05701850 T AT05701850 T AT 05701850T AT E444377 T1 ATE444377 T1 AT E444377T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid characterization
sequencing
acid sequences
characterization
Prior art date
Application number
AT05701850T
Other languages
English (en)
Inventor
Niall Anthony Gormley
Nicholas John Mccooke
Original Assignee
Illumina Cambridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Application granted granted Critical
Publication of ATE444377T1 publication Critical patent/ATE444377T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT05701850T 2004-01-12 2005-01-12 Nukleinsäurecharakterisierung ATE444377T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0400584.9A GB0400584D0 (en) 2004-01-12 2004-01-12 Nucleic acid chacterisation
PCT/GB2005/000080 WO2005068656A1 (en) 2004-01-12 2005-01-12 Nucleic acid characterisation

Publications (1)

Publication Number Publication Date
ATE444377T1 true ATE444377T1 (de) 2009-10-15

Family

ID=31503756

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05701850T ATE444377T1 (de) 2004-01-12 2005-01-12 Nukleinsäurecharakterisierung

Country Status (6)

Country Link
US (1) US20080051294A1 (de)
EP (1) EP1711631B1 (de)
AT (1) ATE444377T1 (de)
DE (1) DE602005016892D1 (de)
GB (1) GB0400584D0 (de)
WO (1) WO2005068656A1 (de)

Families Citing this family (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US7169560B2 (en) * 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
ATE463584T1 (de) * 2004-02-19 2010-04-15 Helicos Biosciences Corp Verfahren zur analyse von polynukleotidsequenzen
US7393665B2 (en) 2005-02-10 2008-07-01 Population Genetics Technologies Ltd Methods and compositions for tagging and identifying polynucleotides
DK1907571T3 (en) 2005-06-15 2017-08-21 Complete Genomics Inc NUCLEIC ACID ANALYSIS USING INCIDENTAL MIXTURES OF NON-OVERLAPPING FRAGMENTS
GB0514935D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Methods for sequencing a polynucleotide template
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
GB0524069D0 (en) 2005-11-25 2006-01-04 Solexa Ltd Preparation of templates for solid phase amplification
EP1987159B2 (de) 2006-02-08 2020-08-12 Illumina Cambridge Limited Verfahren zur sequenzierung einer polynukleotidmatrize
EP2002017B1 (de) 2006-04-04 2015-06-10 Keygene N.V. Nachweis von molekularmarkern mit hohem durchsatz auf der basis von restriktionsfragmenten
DE602007009233D1 (de) 2006-07-12 2010-10-28 Keygene Nv Genomische kartierung mit hohem durchsatz unter verwendung von aflp
US7754429B2 (en) 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
WO2008061193A2 (en) * 2006-11-15 2008-05-22 Biospherex Llc Multitag sequencing and ecogenomics analysis
US12497656B2 (en) 2007-01-26 2025-12-16 Illumina, Inc. Independently removable nucleic acid sequencing system and method
US8315817B2 (en) * 2007-01-26 2012-11-20 Illumina, Inc. Independently removable nucleic acid sequencing system and method
EP2121983A2 (de) 2007-02-02 2009-11-25 Illumina Cambridge Limited Verfahren zur kennzeichnung von proben und sequenzierung mehrerer nukleotidmatrizen
CA2697640C (en) * 2007-09-21 2016-06-21 Katholieke Universiteit Leuven Tools and methods for genetic tests using next generation sequencing
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
US9624489B2 (en) 2008-03-10 2017-04-18 Illumina, Inc. Methods for selecting and amplifying polynucleotides
US8999642B2 (en) 2008-03-10 2015-04-07 Illumina, Inc. Methods for selecting and amplifying polynucleotides
ES2528971T3 (es) 2008-03-17 2015-02-13 Stichting Genetwister Ip Descubrimientos de genes vinculados a la expresión
US8628940B2 (en) 2008-09-24 2014-01-14 Pacific Biosciences Of California, Inc. Intermittent detection during analytical reactions
JP2011515102A (ja) 2008-03-28 2011-05-19 パシフィック バイオサイエンシーズ オブ カリフォルニア， インコーポレイテッド 核酸シーケンシング用組成物及び方法
WO2009133466A2 (en) 2008-04-30 2009-11-05 Population Genetics Technologies Ltd. Asymmetric adapter library construction
US20100129810A1 (en) * 2008-09-05 2010-05-27 Life Technologies Corporation Methods and systems for nucleic acid sequencing validation, calibration and normalization
WO2010048337A2 (en) * 2008-10-22 2010-04-29 Illumina, Inc. Preservation of information related to genomic dna methylation
US20110301042A1 (en) * 2008-11-11 2011-12-08 Helicos Biosciences Corporation Methods of sample encoding for multiplex analysis of samples by single molecule sequencing
JP2012514977A (ja) 2009-01-13 2012-07-05 キージーン・エン・フェー 新規ゲノム配列決定戦略
EP2391732B1 (de) * 2009-01-30 2015-05-27 Oxford Nanopore Technologies Limited Verfahren die adaptoren zur nukleinsaure constructen für transmembrane sequenzierung benutzen
WO2010133972A1 (en) * 2009-05-22 2010-11-25 Population Genetics Technologies Ltd Sorting asymmetrically tagged nucleic acids by selective primer extension
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
DK2456892T3 (en) 2009-07-24 2014-12-08 Illumina Inc Procedure for sequencing of a polynukleotidskabelon
US8948431B2 (en) 2009-12-17 2015-02-03 Bose Corporation Method and apparatus for controlling an electronic system
WO2011103467A2 (en) 2010-02-19 2011-08-25 Life Technologies Corporation Methods and systems for nucleic acid sequencing validation, calibration and normalization
US20110257385A1 (en) * 2010-02-23 2011-10-20 Life Technologies Corporation Methods for flip-strand immobilizing and sequencing nucleic acids
CN101921842B (zh) * 2010-06-30 2013-08-07 深圳华大基因科技有限公司 Hla-a,b基因分型用pcr引物及其使用方法
CN101921841B (zh) * 2010-06-30 2014-03-12 深圳华大基因科技有限公司 基于Illumina GA测序技术的HLA基因高分辨率分型方法
CN101921840B (zh) * 2010-06-30 2014-06-25 深圳华大基因科技有限公司 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法
JP5917519B2 (ja) 2010-09-10 2016-05-18 バイオ−ラッド ラボラトリーズ インコーポレーティッド クロマチン分析のためのｄｎａのサイズ選択
CN102409049B (zh) * 2010-09-21 2013-10-23 深圳华大基因科技服务有限公司 一种基于pcr的dna标签文库构建方法
CN102409044B (zh) * 2010-09-21 2014-05-07 深圳华大基因科技服务有限公司 用于数字基因表达谱的标签及其使用方法
CN102409045B (zh) * 2010-09-21 2013-09-18 深圳华大基因科技服务有限公司 一种基于dna接头连接的标签文库构建方法及其所使用标签和标签接头
CN101967476B (zh) * 2010-09-21 2012-11-14 深圳华大基因科技有限公司 一种基于接头连接的DNA PCR-Free标签文库构建方法
CN102409047B (zh) * 2010-09-21 2014-07-23 深圳华大基因科技服务有限公司 一种构建杂交测序文库的方法
CN102409046B (zh) * 2010-09-21 2013-09-18 深圳华大基因科技服务有限公司 小分子rna标签
AU2012281242B2 (en) 2011-07-08 2016-12-22 Keygene N.V. Sequence based genotyping based on oligonucleotide ligation assays
KR20140050067A (ko) 2011-07-25 2014-04-28 옥스포드 나노포어 테크놀로지즈 리미티드 막횡단 포어를 사용한 이중 가닥 폴리뉴클레오티드 서열분석을 위한 헤어핀 루프 방법
US9200274B2 (en) 2011-12-09 2015-12-01 Illumina, Inc. Expanded radix for polymeric tags
SMT202100154T1 (it) 2012-02-17 2021-05-07 Hutchinson Fred Cancer Res Composizioni e metodi per identificare precisamente mutazioni
WO2013192292A1 (en) * 2012-06-21 2013-12-27 Justin Lamb Massively-parallel multiplex locus-specific nucleic acid sequence analysis
US11155860B2 (en) 2012-07-19 2021-10-26 Oxford Nanopore Technologies Ltd. SSB method
CN103571822B (zh) * 2012-07-20 2016-03-30 中国科学院植物研究所 一种用于新一代测序分析的多重目的dna片段富集方法
EP2914745B1 (de) * 2012-11-05 2017-09-06 Rubicon Genomics, Inc. Strichcodierung von nukleinsäuren
CN103045726B (zh) * 2012-11-20 2015-11-25 南方科技大学 对多个混合dna或rna序列进行基因测序的方法及装置
WO2014089536A1 (en) 2012-12-07 2014-06-12 Invitae Corporation Multiplex nucleic acid detection methods
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
EP2964781B1 (de) 2013-03-08 2018-01-10 Roche Diagnostics GmbH Bluttest auf egfr-mutationen
CA2901545C (en) 2013-03-08 2019-10-08 Oxford Nanopore Technologies Limited Use of spacer elements in a nucleic acid to control movement of a helicase
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
US20170044525A1 (en) 2014-04-29 2017-02-16 Illumina, Inc. Multiplexed single cell gene expression analysis using template switch and tagmentation
CN108350497B (zh) 2015-08-28 2022-07-19 Illumina公司 单细胞核酸序列分析
US10465232B1 (en) 2015-10-08 2019-11-05 Trace Genomics, Inc. Methods for quantifying efficiency of nucleic acid extraction and detection
CN108513581B (zh) 2015-10-13 2022-02-08 国立研究开发法人海洋研究开发机构 双链rna的片段化方法及其利用
WO2017190138A1 (en) * 2016-04-29 2017-11-02 The Regents Of The University Of California Novel methods for quantifying proteins using phage-based sequencing
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
WO2018183942A1 (en) 2017-03-31 2018-10-04 Grail, Inc. Improved library preparation and use thereof for sequencing-based error correction and/or variant identification
CA3089756A1 (en) 2018-01-29 2019-08-01 St. Jude Children's Research Hospital, Inc. Method for nucleic acid amplification
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
JP7431802B2 (ja) 2018-08-15 2024-02-15 イルミナ インコーポレイテッド ライブラリー富化を改善するための組成物および方法
WO2020180778A1 (en) 2019-03-01 2020-09-10 Illumina, Inc. High-throughput single-nuclei and single-cell libraries and methods of making and of using
US20230220377A1 (en) 2019-07-31 2023-07-13 BioSkryb Genomics, Inc. Single cell analysis
US20220316003A1 (en) 2020-03-09 2022-10-06 Illumina, Inc. Methods for sequencing polynucleotides
KR20230020977A (ko) 2020-06-09 2023-02-13 일루미나, 인코포레이티드 시퀀싱 라이브러리의 생성을 증가시키는 방법
EP4373958A1 (de) 2021-07-23 2024-05-29 Illumina, Inc. Verfahren zur herstellung einer substratoberfläche zur dna-sequenzierung
WO2023052629A2 (en) 2021-09-30 2023-04-06 Illumina Cambridge Limited Blocker methods
WO2023069927A1 (en) 2021-10-20 2023-04-27 Illumina, Inc. Methods for capturing library dna for sequencing
CA3223595A1 (en) 2021-12-16 2023-06-22 Xiaoyu Ma Hybrid clustering
CA3223615A1 (en) 2021-12-17 2023-06-22 Fei Shen Orthogonal hybridization
JP2025509651A (ja) 2022-03-15 2025-04-11 イルミナ インコーポレイテッド 並行サンプル及びインデックス配列決定
WO2023175040A2 (en) 2022-03-15 2023-09-21 Illumina, Inc. Concurrent sequencing of forward and reverse complement strands on concatenated polynucleotides for methylation detection
AU2023244497A1 (en) 2022-03-31 2024-01-18 Illumina, Inc. Paired-end re-synthesis using blocked p5 primers
AU2023248405A1 (en) 2022-04-07 2024-01-04 Illumina, Inc. Altered cytidine deaminases and methods of use
WO2024061799A1 (en) 2022-09-19 2024-03-28 Illumina, Inc. Deformable polymers comprising immobilised primers
US20240102067A1 (en) 2022-09-26 2024-03-28 Illumina, Inc. Resynthesis Kits and Methods
US20250388894A1 (en) 2022-09-30 2025-12-25 Illumina, Inc. Methods of using cpg binding proteins in mapping modified cytosine nucleotides
US20240124929A1 (en) 2022-09-30 2024-04-18 Illumina, Inc. Mesophilic compositions for nucleic acid amplification
US20240124914A1 (en) 2022-09-30 2024-04-18 Illumina, Inc. Thermophilic compositions for nucleic acid amplification
US20240110234A1 (en) 2022-09-30 2024-04-04 Illumina, Inc. Amplification Compositions and Methods
WO2024073047A1 (en) 2022-09-30 2024-04-04 Illumina, Inc. Cytidine deaminases and methods of use in mapping modified cytosine nucleotides
US20240110221A1 (en) 2022-09-30 2024-04-04 Illumina, Inc. Methods of modulating clustering kinetics
EP4594481A1 (de) 2022-09-30 2025-08-06 Illumina, Inc. Helicase-cytidindeaminase-komplexe und verfahren zur verwendung
WO2024102283A1 (en) 2022-11-09 2024-05-16 Illumina, Inc. Methods for sequencing long polynucleotides
CA3246533A1 (en) 2022-12-07 2024-06-13 Illumina, Inc. STERIC EXCLUSION MONOCLONAL GROUPING OF DOUBLE-STRANDED DNA WITH PATTERNED ASSEMBLY
WO2024256580A1 (en) 2023-06-14 2024-12-19 Illumina, Inc. Concurrent sequencing with spatially separated rings
EP4728092A1 (de) 2023-06-14 2026-04-22 Illumina, Inc. Bestimmung von modifizierten cytosinen
EP4780981A1 (de) 2023-09-20 2026-07-29 Illumina, Inc. Gleichzeitige sequenzierung mit nick-übersetzung
WO2025062001A1 (en) 2023-09-20 2025-03-27 Illumina, Inc. Optimised nucleic acid sequencing
EP4784740A1 (de) 2023-09-28 2026-08-05 Illumina, Inc. Veränderte cytidindeaminasen und verfahren zur verwendung
WO2025072683A1 (en) 2023-09-29 2025-04-03 Illumina, Inc. Solid supports and methods for strand invasion-based amplification
WO2025081064A2 (en) 2023-10-11 2025-04-17 Illumina, Inc. Thermophilic deaminase and methods for identifying modified cytosine
WO2025137222A1 (en) 2023-12-19 2025-06-26 Illumina, Inc. Methylation detection assay
WO2025137479A1 (en) 2023-12-22 2025-06-26 Illumina, Inc. Reusable flow cells and methods of using them for nucleic acid sequencing
WO2026006774A1 (en) 2024-06-28 2026-01-02 Illumina, Inc. Altered cytidine deaminases and methods of use
WO2026097017A2 (en) 2024-11-01 2026-05-07 Illumina, Inc. Methods of improving sequencing accuracy
WO2026142995A1 (en) 2024-12-26 2026-07-02 Illumina, Inc. Methods for producing singe-cell sequencing libraries of dna originating from open chromatin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770365A (en) * 1995-08-25 1998-06-23 Tm Technologies, Inc. Nucleic acid capture moieties
EP2327797B1 (de) * 1997-04-01 2015-11-25 Illumina Cambridge Limited Verfahren zur Vervielfältigung von Nukleinsäuren
US6322968B1 (en) * 1997-11-21 2001-11-27 Orchid Biosciences, Inc. De novo or “universal” sequencing array
DE19758017C2 (de) * 1997-12-29 2000-03-02 Hanns Ludwig Verfahren zum Nachweis von Borna-Disease-Virus (BDV)-Infektionen über den Nachweis zirkulierender Immunkomplexe und hierfür verwendbarer diagnostischer Kit
US6451525B1 (en) * 1998-12-03 2002-09-17 Pe Corporation (Ny) Parallel sequencing method
ATE318932T1 (de) * 1999-08-13 2006-03-15 Univ Yale Binär kodierte sequenzmarker
WO2002061143A2 (en) * 2001-01-31 2002-08-08 Ambion, Inc. Comparative analysis of nucleic acids using population tagging

Also Published As

Publication number Publication date
WO2005068656A1 (en) 2005-07-28
DE602005016892D1 (de) 2009-11-12
GB0400584D0 (en) 2004-02-11
EP1711631A1 (de) 2006-10-18
EP1711631B1 (de) 2009-09-30
US20080051294A1 (en) 2008-02-28

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