ATE335202T1 - Verfahren zur erfassung von analyten, die aus oberflächengebundenen liganden eluiert werden - Google Patents

Verfahren zur erfassung von analyten, die aus oberflächengebundenen liganden eluiert werden

Info

Publication number
ATE335202T1
ATE335202T1 AT01915984T AT01915984T ATE335202T1 AT E335202 T1 ATE335202 T1 AT E335202T1 AT 01915984 T AT01915984 T AT 01915984T AT 01915984 T AT01915984 T AT 01915984T AT E335202 T1 ATE335202 T1 AT E335202T1
Authority
AT
Austria
Prior art keywords
analytes
liquid
collection
capturing
surface bonded
Prior art date
Application number
AT01915984T
Other languages
English (en)
Inventor
Oesten Jansson
Magnus Malmqvist
Original Assignee
Biacore Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biacore Ab filed Critical Biacore Ab
Application granted granted Critical
Publication of ATE335202T1 publication Critical patent/ATE335202T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/648Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AT01915984T 2000-03-16 2001-03-14 Verfahren zur erfassung von analyten, die aus oberflächengebundenen liganden eluiert werden ATE335202T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19033600P 2000-03-16 2000-03-16

Publications (1)

Publication Number Publication Date
ATE335202T1 true ATE335202T1 (de) 2006-08-15

Family

ID=22700919

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01915984T ATE335202T1 (de) 2000-03-16 2001-03-14 Verfahren zur erfassung von analyten, die aus oberflächengebundenen liganden eluiert werden

Country Status (7)

Country Link
US (2) US6503760B2 (de)
EP (1) EP1264179B1 (de)
JP (1) JP4860085B2 (de)
AT (1) ATE335202T1 (de)
AU (1) AU2001242928A1 (de)
DE (1) DE60121923T2 (de)
WO (1) WO2001069258A1 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE335202T1 (de) * 2000-03-16 2006-08-15 Biacore Ab Verfahren zur erfassung von analyten, die aus oberflächengebundenen liganden eluiert werden
US7518724B2 (en) * 2000-07-11 2009-04-14 Maven Technologies Image acquisition, processing, and display
US6594011B1 (en) 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
US7023547B2 (en) * 2000-07-11 2006-04-04 Maven Technologies, Llc Apparatus including a biochip for imaging of biological samples and method
US7193711B2 (en) * 2000-07-11 2007-03-20 Maven Technologies, Llc Imaging method and apparatus
US6833920B2 (en) * 2000-07-11 2004-12-21 Maven Technologies Llc Apparatus and method for imaging
US7126688B2 (en) * 2000-07-11 2006-10-24 Maven Technologies, Llc Microarray scanning
US20030166007A1 (en) * 2002-01-28 2003-09-04 Mds Proteomics Inc. Chemical proteomics
WO2003064704A1 (en) * 2002-01-28 2003-08-07 Mds Proteomics, Inc. Chemical proteomics
CA2482529A1 (en) * 2002-04-15 2003-10-30 American National Red Cross Method for detecting ligands and targets in a mixture
US6821744B2 (en) * 2002-10-29 2004-11-23 Roche Diagnostics Operations, Inc. Method, assay, and kit for quantifying HIV protease inhibitors
CN1720438A (zh) * 2002-11-29 2006-01-11 日本电气株式会社 分离设备和分离方法
US7736909B2 (en) 2003-01-09 2010-06-15 Board Of Regents, The University Of Texas System Methods and compositions comprising capture agents
US7483140B1 (en) 2004-12-10 2009-01-27 University Of Central Florida Research Foundation, Inc. Micro integrated planar optical waveguide type SPR sensor
US7648844B2 (en) * 2005-05-02 2010-01-19 Bioscale, Inc. Method and apparatus for detection of analyte using an acoustic device
US7300631B2 (en) * 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7749445B2 (en) * 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
US7611908B2 (en) * 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
JP2006313091A (ja) * 2005-05-06 2006-11-16 Fuji Photo Film Co Ltd 結合物質回収方法及び装置
US7843571B2 (en) 2005-09-30 2010-11-30 Fujifilm Corporation Sensing system
JP4768417B2 (ja) * 2005-11-28 2011-09-07 富士フイルム株式会社 バイオセンサー
US7867783B2 (en) * 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7863037B1 (en) 2007-04-04 2011-01-04 Maven Technologies, Llc Ligand binding assays on microarrays in closed multiwell plates
US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
WO2009033056A1 (en) * 2007-09-06 2009-03-12 Bioscale, Inc. Reusable detection surfaces and methods of using same
US8039270B2 (en) * 2008-05-22 2011-10-18 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7981664B1 (en) 2008-05-22 2011-07-19 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
EP2128617A1 (de) * 2008-05-27 2009-12-02 Koninklijke Philips Electronics N.V. Vorrichtung und Verfahren zur Feststellung von Analyten in der Spucke
AU2010256880B2 (en) 2009-06-02 2015-01-22 Opko Health, Inc. Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases
WO2011047257A1 (en) 2009-10-16 2011-04-21 The Board Of Regents Of The University Of Texas System Compositions and methods for producing cyclic peptoid libraries
US8355133B2 (en) * 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms
WO2012075263A1 (en) 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Assay devices with integrated sample dilution and dilution verification and methods of using same
AU2011343813B2 (en) 2010-12-15 2015-05-21 Takeda Pharmaceutical Company Limited Eluate collection using conductivity gradient
JP6701338B2 (ja) 2015-08-10 2020-05-27 エッセンリックス コーポレーション ステップが簡略化され、試料が少なく、スピードアップし、使いやすい、生化学的/化学的なアッセイ装置及び方法
US10132794B2 (en) 2015-09-14 2018-11-20 Essenlix Corporation Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same
AU2016323062A1 (en) 2015-09-14 2018-04-12 Essenlix Corp. Device and system for analyzing a sample, particularly blood, as well as methods of using the same
JP6667052B1 (ja) 2016-12-21 2020-03-18 エッセンリックス コーポレーション 試料を認証するためのデバイスおよび方法ならびにその使用
WO2018148342A1 (en) 2017-02-07 2018-08-16 Essenlix Corporation Compressed open flow assay and use
CA3052962A1 (en) 2017-02-08 2018-08-16 Essenlix Corp. Digital assay
US12066434B2 (en) 2017-02-08 2024-08-20 Essenlix Corporation QMAX assays and applications
WO2018148764A1 (en) 2017-02-08 2018-08-16 Essenlix Corporation Molecular manipulation and assay with controlled temperature
CA3053005A1 (en) 2017-02-08 2018-08-16 Essenlix Corporation Sample collection and handling for delayed analysis
US11927560B2 (en) 2017-02-08 2024-03-12 Essenlix Corporation Bio/chemical material extraction and assay
JP2020507770A (ja) 2017-02-09 2020-03-12 エッセンリックス コーポレーション 比色アッセイ法
EP3580565B1 (de) 2017-02-09 2024-05-29 Essenlix Corporation Assay mit verschiedenen abstandshöhen
WO2018148461A1 (en) 2017-02-09 2018-08-16 Essenlix Corp. Assay with amplification
US12350680B2 (en) 2017-02-15 2025-07-08 Essenlix Corporation Assay with rapid temperature change
CN120195095A (zh) 2017-02-16 2025-06-24 上海宜晟生物科技有限公司 采用纹理化表面的测定方法及装置
EP3638421A4 (de) 2017-06-12 2021-04-07 Essenlix Corporation Homogener assay
WO2019028123A1 (en) 2017-08-01 2019-02-07 Essenlix Corporation COLLECTION, MAINTENANCE AND DETERMINATION OF SAMPLES
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
CN120668916A (zh) 2017-08-01 2025-09-19 上海宜晟生物科技有限公司 检查药物对微生物影响的装置和方法
US12403465B2 (en) 2017-10-11 2025-09-02 Essenlix Corporation Containing a liquid sample
US11393561B2 (en) 2017-10-13 2022-07-19 Essenlix Corporation Devices and methods for authenticating a medical test and use of the same
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
CN107899552B (zh) * 2017-10-31 2020-06-30 苏州博进生物技术有限公司 一种以磁性聚合物微球为基质的金属螯合亲和层析介质
US11648551B2 (en) 2017-12-12 2023-05-16 Essenlix Corporation Sample manipulation and assay with rapid temperature change
US11510608B2 (en) 2017-12-14 2022-11-29 Essenlix Corporation Devices, systems, and methods for monitoring hair
WO2019140334A1 (en) 2018-01-11 2019-07-18 Essenlix Corporation Homogeneous assay (ii)
US20210245153A1 (en) 2018-07-09 2021-08-12 Hewlett-Packard Development Company, L.P. Analyte capturing devices with fluidic ejection devices
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
JP7520824B2 (ja) * 2019-05-08 2024-07-23 株式会社日立ハイテク 自動分析装置の前処理方法
EP4089401B1 (de) * 2021-05-10 2024-11-06 Siemens Aktiengesellschaft Messeinrichtung und verfahren zur messung von mindestens zwei verschiedenen komponenten eines fluids mittels ramanstreuung und chemilumineszenz

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236826A (en) * 1985-12-10 1993-08-17 Murex Corporation Immunoassay for the detection or quantitation of an analyte
US5750338A (en) * 1986-10-23 1998-05-12 Amoco Corporation Target and background capture methods with amplification for affinity assays
US5236849A (en) * 1987-08-11 1993-08-17 Eiji Ishikawa Method of high sensitivity immunoassay
GB8822180D0 (en) * 1988-09-21 1988-10-26 Glaverbel Separation of product of biological process from fluid medium
JPH0466871A (ja) * 1990-07-07 1992-03-03 Eiji Ishikawa 高感度な免疫測定法
US5312730A (en) * 1992-05-27 1994-05-17 Ciba Corning Diagnostics Corp. Immune complex transfer with lypophilic bridge
SE9201976D0 (sv) * 1992-06-26 1992-06-26 Tektolit Ab Haakan Eriksson En metod foer att adsorbera proteiner och peptider till hydrofoba zeoliter
JPH08503698A (ja) * 1992-10-02 1996-04-23 ザ ゼネラル ホスピタル コーポレーション アミノ酸模倣物を溶出試薬として用いる親和精製方法
US5395587A (en) * 1993-07-06 1995-03-07 Smithkline Beecham Corporation Surface plasmon resonance detector having collector for eluted ligate
US5445936A (en) * 1993-09-15 1995-08-29 Ciba Corning Diagnostics Corp. Method for non-competitive binding assays
DE69422604T2 (de) * 1994-03-08 2000-06-08 Zeptosens Ag, Witterwil Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren
JPH08178926A (ja) * 1994-10-25 1996-07-12 Sumitomo Pharmaceut Co Ltd イムノアッセイプレートおよびその用途
WO1996016332A1 (en) * 1994-11-24 1996-05-30 Unipath Limited Recovery of and uses of specific binding agents
JPH08304397A (ja) * 1995-05-11 1996-11-22 Sumitomo Pharmaceut Co Ltd 病原体感染の検出方法
US5756717A (en) * 1995-05-24 1998-05-26 Perseptive Biosystems, Inc Protein imaging
GB9518429D0 (en) * 1995-09-08 1995-11-08 Pharmacia Biosensor A rapid method for providing kinetic and structural data in molecular interaction analysis
EP0879417A1 (de) * 1996-02-09 1998-11-25 Kalibrant Limited Analyse apparat
ATE247830T1 (de) * 1996-05-23 2003-09-15 Inverness Medical Switzerland Verbesserungen in oder in bezug auf spezifische bindungsassays
ATE317979T1 (de) * 1996-12-19 2006-03-15 Dade Behring Marburg Gmbh Immundissoziation zur verbesserung der immunchemischen bestimmung eines analyten
EP0970212A1 (de) * 1997-03-19 2000-01-12 ZymoGenetics, Inc. Zsig32, sekretierte speichelpolypeptide
US6289286B1 (en) * 1998-05-29 2001-09-11 Biacore Ab Surface regeneration of biosensors and characterization of biomolecules associated therewith
JP3829491B2 (ja) * 1998-08-27 2006-10-04 株式会社日立製作所 プローブチップ、プローブチップ作成方法、試料検出方法、及び試料検出装置
US6127129A (en) * 1999-05-04 2000-10-03 Wisconsin Alumni Research Foundation Process to create biomolecule and/or cellular arrays on metal surfaces and product produced thereby
ATE335202T1 (de) * 2000-03-16 2006-08-15 Biacore Ab Verfahren zur erfassung von analyten, die aus oberflächengebundenen liganden eluiert werden

Also Published As

Publication number Publication date
AU2001242928A1 (en) 2001-09-24
US6503760B2 (en) 2003-01-07
JP4860085B2 (ja) 2012-01-25
DE60121923D1 (de) 2006-09-14
US20030077842A1 (en) 2003-04-24
JP2003527606A (ja) 2003-09-16
DE60121923T2 (de) 2006-11-30
US6844201B2 (en) 2005-01-18
US20020012929A1 (en) 2002-01-31
EP1264179B1 (de) 2006-08-02
WO2001069258A1 (en) 2001-09-20
EP1264179A1 (de) 2002-12-11

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