ATE335468T1 - Liposomzusammensetzung von 6,9-bis- (2- - Google Patents

Liposomzusammensetzung von 6,9-bis- (2-

Info

Publication number: ATE335468T1
Authority: AT; Austria
Prior art keywords: bis; liposome composition; liposome; isoquinoline; aminoethyl
Prior art date: 1999-10-22

Application number

AT00977418T

Other languages

English (en)

Inventor

Carlo Bugatti

Original Assignee

Cell Therapeutics Europe Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-22

Filing date

2000-10-19

Publication date

2006-09-15

2000-10-19 Application filed by Cell Therapeutics Europe Srl filed Critical Cell Therapeutics Europe Srl

2006-09-15 Application granted granted Critical

2006-09-15 Publication of ATE335468T1 publication Critical patent/ATE335468T1/de

Links

239000002502 liposome Substances 0.000 title abstract 2
SVAGFBGXEWPNJC-SPIKMXEPSA-N 6,9-bis(2-aminoethylamino)benzo[g]isoquinoline-5,10-dione;(z)-but-2-enedioic acid Chemical compound OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.O=C1C2=CN=CC=C2C(=O)C2=C1C(NCCN)=CC=C2NCCN SVAGFBGXEWPNJC-SPIKMXEPSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT00977418T 1999-10-22 2000-10-19 Liposomzusammensetzung von 6,9-bis- (2- ATE335468T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT1999MI002219A IT1315253B1 (it)	1999-10-22	1999-10-22	Preparazione liposomiale di 6,9-bis-(2-amminoetil)ammino\|benzog\|isochinolin-5,10-dione dimaleato

Publications (1)

Publication Number	Publication Date
ATE335468T1 true ATE335468T1 (de)	2006-09-15

Family

ID=11383836

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00977418T ATE335468T1 (de)	1999-10-22	2000-10-19	Liposomzusammensetzung von 6,9-bis- (2-

Country Status (23)

Country	Link
US (1)	US7449197B2 (de)
EP (1)	EP1221940B1 (de)
JP (1)	JP2003512313A (de)
KR (1)	KR20020063880A (de)
CN (1)	CN1164261C (de)
AT (1)	ATE335468T1 (de)
AU (1)	AU772339B2 (de)
BR (1)	BR0014881A (de)
CA (1)	CA2386143A1 (de)
CZ (1)	CZ20021388A3 (de)
DE (1)	DE60029979T2 (de)
EA (1)	EA004477B1 (de)
ES (1)	ES2269200T3 (de)
HU (1)	HUP0203473A3 (de)
IL (2)	IL149212A0 (de)
IT (1)	IT1315253B1 (de)
MX (1)	MXPA02003939A (de)
NO (1)	NO20021867D0 (de)
NZ (1)	NZ518005A (de)
PL (1)	PL197412B1 (de)
SK (1)	SK284247B6 (de)
WO (1)	WO2001028521A2 (de)
ZA (1)	ZA200203128B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000035422A2 (en) *	1998-12-18	2000-06-22	Hadasit Medical Research Services & Development Ltd.	Method of administering a compound to multi-drug resistant cells
ITMI20021040A1 (it) *	2002-05-16	2003-11-17	Novuspharma Spa	Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
CN1305881C (zh) *	2004-08-13	2007-03-21	河南工业大学	磷脂酰胆碱的制备方法
CN103479578B (zh) *	2012-06-14	2016-08-03	沈阳药科大学	一种马来酸匹杉琼的脂质体制剂及其制备工艺
CN105596295B (zh) *	2016-01-25	2018-03-16	北京博恩特药业有限公司	马来酸匹杉琼脂质体及其制备方法
CN105997896B (zh) *	2016-05-28	2019-07-05	长沙秋点兵信息科技有限公司	治疗非霍奇金淋巴瘤的注射用冻干粉及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4797285A (en) *	1985-12-06	1989-01-10	Yissum Research And Development Company Of The Hebrew University Of Jerusalem	Lipsome/anthraquinone drug composition and method
JPS6442418A (en) *	1985-12-06	1989-02-14	Yissum Res Dev Co	Liposome/anthraquinone drug composition and therapy therewith
MX9203808A (es) *	1987-03-05	1992-07-01	Liposome Co Inc	Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US5013556A (en) *	1989-10-20	1991-05-07	Liposome Technology, Inc.	Liposomes with enhanced circulation time
ES2072223B1 (es) *	1993-11-25	1996-03-16	Lipotec Sa	Liposomas encapsulando doxorubicina.
US5776488A (en) *	1994-03-11	1998-07-07	Yoshitomi Pharmaceutical Industries, Ltd.	Liposome preparation
US5587382A (en) *	1994-03-28	1996-12-24	Boehringer Mannheim Italia, Spa	6,9-bis[(2-aminoethyl) amino]benzo [g]isoquinoline-5,10- dione dimaleate; an aza-anthracenedione with reduced cardiotoxicity
US5506232A (en) *	1994-03-28	1996-04-09	Boehringer Mannheim Italia S.P.A.	6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and its dimaleate salt
US6726924B2 (en) *	1997-09-04	2004-04-27	Biozone Laboratories, Inc.	Oral liposomal delivery system

1999
- 1999-10-22 IT IT1999MI002219A patent/IT1315253B1/it active
2000
- 2000-10-19 WO PCT/EP2000/010303 patent/WO2001028521A2/en not_active Ceased
- 2000-10-19 ES ES00977418T patent/ES2269200T3/es not_active Expired - Lifetime
- 2000-10-19 PL PL354610A patent/PL197412B1/pl not_active IP Right Cessation
- 2000-10-19 IL IL14921200A patent/IL149212A0/xx active IP Right Grant
- 2000-10-19 MX MXPA02003939A patent/MXPA02003939A/es active IP Right Grant
- 2000-10-19 CA CA002386143A patent/CA2386143A1/en not_active Abandoned
- 2000-10-19 CZ CZ20021388A patent/CZ20021388A3/cs unknown
- 2000-10-19 HU HU0203473A patent/HUP0203473A3/hu unknown
- 2000-10-19 AU AU15146/01A patent/AU772339B2/en not_active Ceased
- 2000-10-19 EA EA200200389A patent/EA004477B1/ru not_active IP Right Cessation
- 2000-10-19 CN CNB008146004A patent/CN1164261C/zh not_active Expired - Fee Related
- 2000-10-19 KR KR1020027004996A patent/KR20020063880A/ko not_active Ceased
- 2000-10-19 SK SK538-2002A patent/SK284247B6/sk not_active IP Right Cessation
- 2000-10-19 BR BR0014881-4A patent/BR0014881A/pt not_active Application Discontinuation
- 2000-10-19 DE DE60029979T patent/DE60029979T2/de not_active Expired - Fee Related
- 2000-10-19 AT AT00977418T patent/ATE335468T1/de not_active IP Right Cessation
- 2000-10-19 EP EP00977418A patent/EP1221940B1/de not_active Expired - Lifetime
- 2000-10-19 NZ NZ518005A patent/NZ518005A/en unknown
- 2000-10-19 JP JP2001531351A patent/JP2003512313A/ja active Pending
2002
- 2002-04-18 IL IL149212A patent/IL149212A/en not_active IP Right Cessation
- 2002-04-19 NO NO20021867A patent/NO20021867D0/no not_active Application Discontinuation
- 2002-04-19 ZA ZA200203128A patent/ZA200203128B/en unknown
2005
- 2005-11-21 US US11/283,941 patent/US7449197B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL149212A0 (en)	2002-11-10
ZA200203128B (en)	2003-06-05
CZ20021388A3 (cs)	2002-08-14
ES2269200T3 (es)	2007-04-01
AU1514601A (en)	2001-04-30
ITMI992219A1 (it)	2001-04-22
US20060078607A1 (en)	2006-04-13
EP1221940A2 (de)	2002-07-17
WO2001028521A2 (en)	2001-04-26
DE60029979T2 (de)	2007-02-22
BR0014881A (pt)	2002-06-11
PL197412B1 (pl)	2008-03-31
KR20020063880A (ko)	2002-08-05
EP1221940B1 (de)	2006-08-09
NO20021867L (no)	2002-04-19
WO2001028521A3 (en)	2002-04-25
NO20021867D0 (no)	2002-04-19
DE60029979D1 (de)	2006-09-21
SK5382002A3 (en)	2002-09-10
US7449197B2 (en)	2008-11-11
PL354610A1 (en)	2004-02-09
CN1164261C (zh)	2004-09-01
NZ518005A (en)	2003-10-31
HUP0203473A3 (en)	2003-12-29
IL149212A (en)	2006-12-10
EA200200389A1 (ru)	2002-08-29
SK284247B6 (sk)	2004-12-01
JP2003512313A (ja)	2003-04-02
CN1382039A (zh)	2002-11-27
MXPA02003939A (es)	2004-06-25
HUP0203473A2 (hu)	2003-02-28
IT1315253B1 (it)	2003-02-03
EA004477B1 (ru)	2004-04-29
AU772339B2 (en)	2004-04-22
CA2386143A1 (en)	2001-04-26

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Legal Events

Date	Code	Title	Description
2007-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties