HUP0203473A3 - Liposome composition of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate - Google Patents

Liposome composition of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate

Info

Publication number
HUP0203473A3
HUP0203473A3 HU0203473A HUP0203473A HUP0203473A3 HU P0203473 A3 HUP0203473 A3 HU P0203473A3 HU 0203473 A HU0203473 A HU 0203473A HU P0203473 A HUP0203473 A HU P0203473A HU P0203473 A3 HUP0203473 A3 HU P0203473A3
Authority
HU
Hungary
Prior art keywords
isoquinoline
aminoethyl
benzo
bis
amino
Prior art date
Application number
HU0203473A
Other languages
English (en)
Original Assignee
Novuspharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novuspharma Spa filed Critical Novuspharma Spa
Publication of HUP0203473A2 publication Critical patent/HUP0203473A2/hu
Publication of HUP0203473A3 publication Critical patent/HUP0203473A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU0203473A 1999-10-22 2000-10-19 Liposome composition of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate HUP0203473A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI002219A IT1315253B1 (it) 1999-10-22 1999-10-22 Preparazione liposomiale di 6,9-bis-(2-amminoetil)ammino|benzog|isochinolin-5,10-dione dimaleato
PCT/EP2000/010303 WO2001028521A2 (en) 1999-10-22 2000-10-19 Liposome formulation of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate

Publications (2)

Publication Number Publication Date
HUP0203473A2 HUP0203473A2 (hu) 2003-02-28
HUP0203473A3 true HUP0203473A3 (en) 2003-12-29

Family

ID=11383836

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203473A HUP0203473A3 (en) 1999-10-22 2000-10-19 Liposome composition of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate

Country Status (23)

Country Link
US (1) US7449197B2 (hu)
EP (1) EP1221940B1 (hu)
JP (1) JP2003512313A (hu)
KR (1) KR20020063880A (hu)
CN (1) CN1164261C (hu)
AT (1) ATE335468T1 (hu)
AU (1) AU772339B2 (hu)
BR (1) BR0014881A (hu)
CA (1) CA2386143A1 (hu)
CZ (1) CZ20021388A3 (hu)
DE (1) DE60029979T2 (hu)
EA (1) EA004477B1 (hu)
ES (1) ES2269200T3 (hu)
HU (1) HUP0203473A3 (hu)
IL (2) IL149212A0 (hu)
IT (1) IT1315253B1 (hu)
MX (1) MXPA02003939A (hu)
NO (1) NO20021867D0 (hu)
NZ (1) NZ518005A (hu)
PL (1) PL197412B1 (hu)
SK (1) SK284247B6 (hu)
WO (1) WO2001028521A2 (hu)
ZA (1) ZA200203128B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE385778T1 (de) * 1998-12-18 2008-03-15 Hadasit Med Res Service Verfahren zur verabreichung von einer verbindung an mehrfachresistente zellen
ITMI20021040A1 (it) * 2002-05-16 2003-11-17 Novuspharma Spa Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
CN1305881C (zh) * 2004-08-13 2007-03-21 河南工业大学 磷脂酰胆碱的制备方法
CN103479578B (zh) * 2012-06-14 2016-08-03 沈阳药科大学 一种马来酸匹杉琼的脂质体制剂及其制备工艺
CN105596295B (zh) * 2016-01-25 2018-03-16 北京博恩特药业有限公司 马来酸匹杉琼脂质体及其制备方法
CN105997896B (zh) * 2016-05-28 2019-07-05 长沙秋点兵信息科技有限公司 治疗非霍奇金淋巴瘤的注射用冻干粉及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797285A (en) * 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
JPS6442418A (en) * 1985-12-06 1989-02-14 Yissum Res Dev Co Liposome/anthraquinone drug composition and therapy therewith
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
ES2072223B1 (es) * 1993-11-25 1996-03-16 Lipotec Sa Liposomas encapsulando doxorubicina.
EP0750910A4 (en) * 1994-03-11 1997-07-09 Yoshitomi Pharmaceutical PREPARATION OF LIPOSOMES
US5587382A (en) * 1994-03-28 1996-12-24 Boehringer Mannheim Italia, Spa 6,9-bis[(2-aminoethyl) amino]benzo [g]isoquinoline-5,10- dione dimaleate; an aza-anthracenedione with reduced cardiotoxicity
US5506232A (en) * 1994-03-28 1996-04-09 Boehringer Mannheim Italia S.P.A. 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and its dimaleate salt
WO1999011242A1 (en) * 1997-09-04 1999-03-11 Biozone Laboratories, Inc. Oral liposomal delivery system

Also Published As

Publication number Publication date
PL197412B1 (pl) 2008-03-31
CA2386143A1 (en) 2001-04-26
WO2001028521A2 (en) 2001-04-26
AU1514601A (en) 2001-04-30
IT1315253B1 (it) 2003-02-03
JP2003512313A (ja) 2003-04-02
NO20021867L (no) 2002-04-19
ZA200203128B (en) 2003-06-05
PL354610A1 (en) 2004-02-09
HUP0203473A2 (hu) 2003-02-28
EA200200389A1 (ru) 2002-08-29
US20060078607A1 (en) 2006-04-13
SK5382002A3 (en) 2002-09-10
US7449197B2 (en) 2008-11-11
ITMI992219A1 (it) 2001-04-22
CN1164261C (zh) 2004-09-01
CZ20021388A3 (cs) 2002-08-14
AU772339B2 (en) 2004-04-22
DE60029979D1 (de) 2006-09-21
IL149212A0 (en) 2002-11-10
EA004477B1 (ru) 2004-04-29
MXPA02003939A (es) 2004-06-25
KR20020063880A (ko) 2002-08-05
NO20021867D0 (no) 2002-04-19
SK284247B6 (sk) 2004-12-01
BR0014881A (pt) 2002-06-11
ATE335468T1 (de) 2006-09-15
EP1221940B1 (en) 2006-08-09
EP1221940A2 (en) 2002-07-17
IL149212A (en) 2006-12-10
NZ518005A (en) 2003-10-31
ES2269200T3 (es) 2007-04-01
DE60029979T2 (de) 2007-02-22
WO2001028521A3 (en) 2002-04-25
CN1382039A (zh) 2002-11-27

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees