ATE336591T1 - Nachweisverfahren für kurze sequenzvarianten - Google Patents

Nachweisverfahren für kurze sequenzvarianten

Info

Publication number
ATE336591T1
ATE336591T1 AT00970925T AT00970925T ATE336591T1 AT E336591 T1 ATE336591 T1 AT E336591T1 AT 00970925 T AT00970925 T AT 00970925T AT 00970925 T AT00970925 T AT 00970925T AT E336591 T1 ATE336591 T1 AT E336591T1
Authority
AT
Austria
Prior art keywords
detection methods
sequence variants
short sequence
gene
oligonucletide
Prior art date
Application number
AT00970925T
Other languages
German (de)
English (en)
Inventor
Sanjay Tyagi
Fred R Kramer
David Alland
Original Assignee
New York Health Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Health Res Inst filed Critical New York Health Res Inst
Application granted granted Critical
Publication of ATE336591T1 publication Critical patent/ATE336591T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00970925T 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten ATE336591T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16109699P 1999-10-22 1999-10-22

Publications (1)

Publication Number Publication Date
ATE336591T1 true ATE336591T1 (de) 2006-09-15

Family

ID=22579803

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00970925T ATE336591T1 (de) 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten

Country Status (8)

Country Link
US (2) US7662550B1 (fr)
EP (1) EP1230387B1 (fr)
JP (1) JP4919568B2 (fr)
AT (1) ATE336591T1 (fr)
AU (1) AU781945B2 (fr)
CA (1) CA2387306C (fr)
DE (1) DE60030145T2 (fr)
WO (1) WO2001031062A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6893868B2 (en) 1997-02-20 2005-05-17 Onco Immunin, Inc. Homo-doubly labeled compositions for the detection of enzyme activity in biological samples
US6037137A (en) 1997-02-20 2000-03-14 Oncoimmunin, Inc. Fluorogenic peptides for the detection of protease activity
US7312302B2 (en) 1997-02-20 2007-12-25 Oncolmmunin, Inc. Compositions for the detection of enzyme activity in biological samples and methods of use thereof
US7019129B1 (en) * 2000-05-09 2006-03-28 Biosearch Technologies, Inc. Dark quenchers for donor-acceptor energy transfer
EP1440311B1 (fr) * 2001-08-31 2009-01-07 Gen-Probe Incorporated Sondes presentant differentes affinites pour quantifier des polynucleotides d'un analyte
JP2005534307A (ja) * 2002-07-26 2005-11-17 ベクトン・ディキンソン・アンド・カンパニー 核酸検定の読み取り値を解析する方法、および、その装置
WO2006029014A2 (fr) * 2004-09-02 2006-03-16 The Regents Of The University Of Colorado Sondes oligonucleotidiques d'arnr de detection specifique de mycobacteries et leurs procedes d'utilisation
RU2460804C2 (ru) * 2004-10-18 2012-09-10 Брандейс Юнивесити Способ гомогенной детекции по меньшей мере одного продукта одноцепочечной амплификации
JP2006217909A (ja) * 2005-01-11 2006-08-24 Fuji Photo Film Co Ltd 抗酸菌属細菌の検出方法およびそのキット
US7584947B2 (en) * 2005-05-20 2009-09-08 The Boeing Company Reconfigurable workpiece support fixture
WO2009124150A2 (fr) 2008-04-01 2009-10-08 Biosearch Technologies, Inc. Sondes de désactiveur-fluorophore sombres d’acide nucléique stabilisé
AU2010276236B2 (en) 2009-07-21 2014-03-20 Gen-Probe Incorporated Methods and compositions for quantitative detection of nucleic acid sequences over an extended dynamic range
ES2743959T3 (es) 2009-10-21 2020-02-21 Univ Brandeis Kits para analizar secuencias de ácido nucleico monocatenario
EP3135775B1 (fr) * 2010-11-10 2018-06-27 Brandeis University Kit de detection et d'identification de mycobacterie
JP2013092393A (ja) * 2011-10-24 2013-05-16 Sony Corp ケミカルセンサ、生体分子検出装置及び生体分子検出方法
KR102047569B1 (ko) * 2011-11-30 2019-11-21 소니 주식회사 케미컬 센서, 케미컬 센서 모듈, 화학물질 검출 장치 및 화학물질 검출 방법
CN114717296B (zh) 2012-02-03 2025-04-04 加州理工学院 多路生化测定中信号的编码和解码
WO2013131083A1 (fr) 2012-03-02 2013-09-06 Winthrop-University Hospital Procédé pour l'utilisation d'une détection par pcr à l'aide d'une sonde pour mesurer les niveaux d'adn en circulation provenant de cellules bêta déméthylées, comme mesure de la perte de cellules bêta en cas de diabète
EP3901243A1 (fr) 2012-08-03 2021-10-27 California Institute of Technology Multiplexage et quantification dans pcr avec exigences et matériel réduits
LT3957753T (lt) 2014-10-10 2025-01-10 Rutgers, The State University Of New Jersey Polimerazės grandininės reakcijos pradmenys ir zondai, skirti mycobacterium tuberculosis
US20160289734A1 (en) 2015-04-03 2016-10-06 University Of Massachusetts Methods of using oligonucleotide-guided argonaute proteins
WO2017173035A1 (fr) 2016-04-01 2017-10-05 Chromacode Inc. Sondes compétitives destinées à la production d'un signal d'ingénierie
US10066263B2 (en) 2016-06-17 2018-09-04 California Institute Of Technology Nucleic acid reactions and related methods and compositions
CN107058589A (zh) * 2017-06-09 2017-08-18 苏州达麦迪生物医学科技有限公司 一种快速检测尿路感染细菌的分子信标探针、试剂盒及方法
US12454720B2 (en) 2018-04-17 2025-10-28 ChromaCode, Inc. Methods and systems for multiplex analysis
US12203129B2 (en) 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays
CN116287425A (zh) * 2021-12-21 2023-06-23 广东菲鹏生物有限公司 一种进行hpv检测或分型的探针及其引物探针组合物
CN116287107A (zh) * 2021-12-21 2023-06-23 广东菲鹏生物有限公司 一种核酸探针及其使用方法
CN118891381A (zh) * 2022-02-28 2024-11-01 新加坡国立大学 分析微生物组成物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2031659A1 (fr) * 1990-01-26 1991-07-27 John B. Findlay Reactif hydrosoluble; sonde d'acide nucleique; trousse d'essai et diagnostic; methodes de purification
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
AU713667B2 (en) * 1996-04-12 1999-12-09 Phri Properties, Inc. Detection probes, kits and assays
CA2303414C (fr) * 1997-09-12 2008-05-20 Phri Properties, Inc. Procedes de co-amplification non competitive
ATE478090T1 (de) * 1997-10-27 2010-09-15 Boston Probes Inc SICH AUF ßPNA MOLECULAR BEACONSß BEZIEHENDE VERFAHREN, TESTSÄTZE UND ZUSAMMENSETZUNGEN
CA2318880C (fr) * 1998-02-04 2010-07-27 Applied Biosystems, Llc Determination d'un genotype d'un produit d'amplification sur des sites alleliques multiples
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits

Also Published As

Publication number Publication date
US20100120048A1 (en) 2010-05-13
JP2003518924A (ja) 2003-06-17
AU781945B2 (en) 2005-06-23
US9260761B2 (en) 2016-02-16
CA2387306C (fr) 2010-04-27
JP4919568B2 (ja) 2012-04-18
EP1230387A1 (fr) 2002-08-14
DE60030145T2 (de) 2008-01-10
EP1230387A4 (fr) 2003-03-05
DE60030145D1 (de) 2006-09-28
WO2001031062A1 (fr) 2001-05-03
AU8024000A (en) 2001-05-08
EP1230387B1 (fr) 2006-08-16
CA2387306A1 (fr) 2001-05-03
US7662550B1 (en) 2010-02-16

Similar Documents

Publication Publication Date Title
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
EP1288313A3 (fr) Système et méthode pour analyser des molécules d'acide nucléique
WO2003100012A3 (fr) Jeux ordonnes de microechantillons et procede permettant de declencher une reaction d'hybridation pour plusieurs echantillons sur un seul jeu ordonne
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
DE60016415D1 (de) Genetisches versuchssystem
DE69724209D1 (de) Erkennung einer genetischen prädisposition fur osteoporose
ATE368125T1 (de) Verfahren zur erkennung von einzel-nukleotid- polymorphismen
DE60140120D1 (de) Toxizitätstypisierung unter verwendung von leberstammzellen
DK0805876T3 (da) Nukleinsyreamplifikationsoligonukleotider og prober til Lyme-sygdom-associeret Borrelia
WO2000034525A8 (fr) Typage de toxicite utilisant des corps embryoides
DE69917636D1 (en) Polymerasesignalversuch
DK0975800T3 (da) Analyse af nukleotider i opløsning under anvendelse af PNA-prober
DE60143314D1 (de) Estimmung der präsenz von cryptosporidium organismen in einer testprobe
ATE264922T1 (de) Verfahren zur erkennung von klonalen populationen von transformierten zellen in einer genomisch heterogenen zellulären probe
IL149791A0 (en) Oligonucleotides and assemblies thereof useful in the detection of the presence or absence of target nucleic acid sequences in a sample
WO2005027710A3 (fr) Procedes d'identification de sujets a risque pour le melanome et traitements correspondants
WO2001029262A3 (fr) Reactifs de genotypage, kits et procedes d'utilisation desdits reactifs
RU99100445A (ru) Способ индикации микроорганизмов
DE59814032D1 (de) Nucleinsäuremolekül, kit und verwendung
WO2004000995A3 (fr) Procedes, sondes et molecules accessoires permettant de detecter des polymorphismes nucleotidiques uniques
ATE298786T1 (de) In situ-hybridisierungs-anordnung zum spezifischen nachweis von mikroorganismen
DE69636917D1 (de) Nucleinsäuresonden und Amplifizierungsoligonukleotide für Neisseria Spezies
WO2001040522A3 (fr) Sequences nucleotidiques partagees courtes
WO2003048770A3 (fr) Procede pour effectuer un diagnostic in vitro au moyen de mecanismes de regulation genetique et trousse de diagnostic correspondante
WO2003014879A3 (fr) Systeme et methode d'identification d'un facteur de risque genetique pour une maladie ou une pathologie

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties