ATE412737T1 - Virusreinigung mit ultrafiltration - Google Patents
Virusreinigung mit ultrafiltrationInfo
- Publication number
- ATE412737T1 ATE412737T1 AT06724513T AT06724513T ATE412737T1 AT E412737 T1 ATE412737 T1 AT E412737T1 AT 06724513 T AT06724513 T AT 06724513T AT 06724513 T AT06724513 T AT 06724513T AT E412737 T1 ATE412737 T1 AT E412737T1
- Authority
- AT
- Austria
- Prior art keywords
- ultrafiltration
- virus
- virus cleaning
- adenovirus
- cleaning
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 2
- 238000000108 ultra-filtration Methods 0.000 title abstract 2
- 238000004140 cleaning Methods 0.000 title 1
- 241000701161 unidentified adenovirus Species 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000012466 permeate Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000012465 retentate Substances 0.000 abstract 1
- 238000005199 ultracentrifugation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10051—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67006405P | 2005-04-11 | 2005-04-11 | |
| EP05102842 | 2005-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE412737T1 true ATE412737T1 (de) | 2008-11-15 |
Family
ID=36572264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06724513T ATE412737T1 (de) | 2005-04-11 | 2006-04-11 | Virusreinigung mit ultrafiltration |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8574595B2 (de) |
| EP (1) | EP1869171B2 (de) |
| CN (1) | CN101155915B (de) |
| AT (1) | ATE412737T1 (de) |
| AU (1) | AU2006233800B2 (de) |
| CA (1) | CA2602944C (de) |
| DE (1) | DE602006003420D1 (de) |
| DK (1) | DK1869171T4 (de) |
| ES (1) | ES2317517T5 (de) |
| WO (1) | WO2006108707A1 (de) |
Families Citing this family (62)
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| EP1815029A4 (de) * | 2004-11-03 | 2009-06-10 | Introgen Therapeutics Inc | Neues verfahren zur herstellung und reinigung von adenovirusvektoren |
| EP1998804B1 (de) * | 2006-03-27 | 2014-04-16 | Crucell Holland B.V. | Zusammensetzungen, die einen rekombinanten adenovirus und ein adjuvans umfassen |
| FR2907453B1 (fr) | 2006-10-24 | 2008-12-26 | Sanofi Aventis Sa | Nouveaux derives du fluorene,compositions les contenant et utilisation |
| US20080131955A1 (en) * | 2006-11-30 | 2008-06-05 | Canon U.S. Life Sciences, Inc. | Method of Separating Target DNA from Mixed DNA |
| PL2195418T3 (pl) * | 2007-10-02 | 2013-05-31 | Ptc Phage Tech Center Gmbh | Sposób i układ do oczyszczania na skalę przemysłową bakteriofagów z przeznaczeniem do terapii bakteriofagowej |
| AU2008345218B2 (en) * | 2007-12-28 | 2015-02-19 | Takeda Pharmaceutical Company Limited | Counter-pressure filtration of proteins |
| US10273502B2 (en) * | 2008-06-18 | 2019-04-30 | Oxford Biomedica (Uk) Limited | Virus purification |
| US10041049B2 (en) | 2008-11-03 | 2018-08-07 | Janssen Vaccines & Prevention B.V. | Method for the production of adenoviral vectors |
| FR2944292B1 (fr) | 2009-04-08 | 2013-08-23 | Sanofi Pasteur | Procede de purification du virus rabique |
| CA2777116C (en) | 2009-10-15 | 2020-09-01 | Crucell Holland B.V. | Process for adenovirus purification from high cell density cultures |
| EA028623B1 (ru) | 2009-10-15 | 2017-12-29 | Янссен Вэксинс Энд Превеншн Б.В. | Способ очистки аденовирусных частиц |
| KR101820980B1 (ko) | 2010-02-15 | 2018-01-22 | 얀센 백신스 앤드 프리벤션 비.브이. | Ad 26 아데노바이러스 벡터를 제조하는 방법 |
| US9644187B2 (en) | 2010-04-14 | 2017-05-09 | Emd Millipore Corporation | Methods of producing high titer, high purity virus stocks and methods of use thereof |
| US20130224245A1 (en) * | 2010-06-01 | 2013-08-29 | Novartis Ag | Concentration of vaccine antigens without lyophilization |
| WO2012019354A1 (en) | 2010-08-12 | 2012-02-16 | Yisheng Biopharma Holdings Ltd. | Method for reducing dna impurities in viral compositions |
| AP3390A (en) | 2010-09-20 | 2015-08-31 | Crucell Holland Bv | Therapeutic vaccination against active tuberculosis |
| WO2012041669A1 (en) | 2010-09-27 | 2012-04-05 | Crucell Holland B.V. | Heterologous prime boost vaccination regimen against malaria |
| US10906934B2 (en) * | 2011-03-25 | 2021-02-02 | Genentech, Inc. | Protein purification methods |
| WO2013022764A1 (en) | 2011-08-05 | 2013-02-14 | David Kirn | Methods and compositions for production of vaccina virus |
| CN102688485A (zh) * | 2011-09-16 | 2012-09-26 | 扬州优邦生物制药有限公司 | 一种猪细小病毒灭活疫苗的制备方法 |
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| US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| PL2825640T3 (pl) | 2012-03-12 | 2016-10-31 | Partie rekombinowanych adenowirusów o zmienionych końcach | |
| US9125870B2 (en) | 2012-03-22 | 2015-09-08 | Crucell Holland B.V. | Vaccine against RSV |
| AP2014007994A0 (en) | 2012-03-22 | 2014-10-31 | Crucell Holland Bv | Vaccine against rsv |
| CN103923883A (zh) * | 2013-01-16 | 2014-07-16 | 辽宁成大生物股份有限公司 | 一种流感病毒的浓缩、纯化方法 |
| PE20151867A1 (es) | 2013-04-25 | 2016-01-07 | Crucell Holland Bv | Polipeptidos f de prefusion del virus sincicial respiratorio (rsv )solubles y estabilizados |
| CA2914792C (en) | 2013-06-17 | 2024-02-27 | Crucell Holland B.V. | Stabilized soluble pre-fusion rsv f polypeptides |
| US11066678B2 (en) | 2013-07-18 | 2021-07-20 | Children's Hospital Medical Center | Methods of improving titer in transfection-based production systems using eukaryotic cells |
| CN103601793A (zh) * | 2013-10-23 | 2014-02-26 | 乾元浩生物股份有限公司 | 一种禽用疫苗抗原纯化的方法 |
| EP4218991A1 (de) * | 2014-05-13 | 2023-08-02 | Amgen Inc. | Prozesssteuerungssysteme und verfahren zur verwendung mit filtern und filtrationsverfahren |
| CN114797474A (zh) * | 2014-05-21 | 2022-07-29 | 非链实验室 | 用于缓冲溶液交换的系统和方法 |
| JP6385559B2 (ja) * | 2014-07-24 | 2018-09-05 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 細胞培養体からのポリオウイルスの精製プロセス |
| US10570417B2 (en) | 2015-04-14 | 2020-02-25 | Janssen Vaccines & Prevention B.V. | Recombinant adenovirus expressing two transgenes with a bidirectional promoter |
| CN107847581B (zh) | 2015-07-07 | 2022-03-22 | 扬森疫苗与预防公司 | 稳定化的可溶性融合前rsv f多肽 |
| CA2991002C (en) | 2015-07-07 | 2023-11-28 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
| MY193584A (en) | 2016-04-05 | 2022-10-19 | Janssen Vaccines & Prevention Bv | Vaccine against rsv |
| PT3439672T (pt) | 2016-04-05 | 2021-02-24 | Janssen Vaccines & Prevention Bv | Proteína f do rsv pré-fusão solúvel e estabilizada para uso na profilaxia de infeção por rsv |
| KR102573534B1 (ko) | 2016-05-12 | 2023-08-31 | 얀센 백신스 앤드 프리벤션 비.브이. | 강력하고 균형 잡힌 양방향성 프로모터 |
| US10953087B2 (en) | 2016-05-30 | 2021-03-23 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion RSV F proteins |
| WO2017220499A1 (en) | 2016-06-20 | 2017-12-28 | Janssen Vaccines & Prevention B.V. | Potent and balanced bidirectional promoter |
| WO2018011196A1 (en) | 2016-07-14 | 2018-01-18 | Janssen Vaccines & Prevention B.V. | Hpv vaccines |
| EP3559216A1 (de) * | 2016-12-22 | 2019-10-30 | Blue Sky Vaccines GmbH | Verfahren zur reinigung eines virus |
| CA3053212C (en) | 2017-02-09 | 2021-04-13 | Janssen Vaccines & Prevention B.V. | Potent and short promoter for expression of heterologous genes |
| CN110959038A (zh) * | 2017-05-15 | 2020-04-03 | C-乐克塔股份有限公司 | 酶产物 |
| US11229692B2 (en) | 2017-05-17 | 2022-01-25 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
| CN107603959A (zh) * | 2017-08-30 | 2018-01-19 | 四川大学 | 提高缓冲液盐离子浓度纯化病毒的方法 |
| CN111163800A (zh) | 2017-09-15 | 2020-05-15 | 扬森疫苗与预防公司 | 用于安全诱导针对rsv的免疫的方法 |
| GB201806736D0 (en) * | 2018-04-25 | 2018-06-06 | Ge Healthcare Bioprocess R&D Ab | Method for virus purification |
| EP3880243A1 (de) | 2018-11-13 | 2021-09-22 | Janssen Vaccines & Prevention B.V. | Stabilisierte präfusionierte rsv-f-proteine |
| CN111454914A (zh) * | 2019-01-18 | 2020-07-28 | 嘉兴安宇生物科技有限公司 | 一种腺病毒快速纯化方法 |
| PH12021552797A1 (en) * | 2019-05-14 | 2022-09-19 | Janssen Biotech Inc | Ultrafiltration/diafiltration (uf/df) process |
| CN110129287B (zh) * | 2019-05-15 | 2023-07-14 | 青岛蔚蓝生物制品有限公司 | 一种猪伪狂犬病毒双重超滤系统及纯化方法 |
| CN111394390A (zh) * | 2020-03-26 | 2020-07-10 | 赛诺(深圳)生物医药研究有限公司 | 用于新型冠状病毒基因疫苗的批量生产重组腺病毒的方法 |
| CN111575244B (zh) * | 2020-05-06 | 2021-07-23 | 江苏金迪克生物技术股份有限公司 | 一种低Vero细胞残留DNA狂犬病疫苗原液的制备方法 |
| CN112226418B (zh) * | 2020-09-25 | 2022-07-08 | 阜外华中心血管病医院 | 重组腺相关病毒纯化方法 |
| CA3203570A1 (en) * | 2020-12-10 | 2022-06-16 | Astrazeneca Uk Limited | Methods of purifying adenovirus |
| CN112899242A (zh) * | 2021-02-03 | 2021-06-04 | 苏州博腾生物制药有限公司 | 慢病毒纯化工艺 |
| CN113373120B (zh) * | 2021-06-18 | 2022-04-26 | 浙江康佰裕生物科技有限公司 | Gmp级逆转录病毒载体的纯化方法与应用 |
| CN113817689B (zh) * | 2021-11-22 | 2023-10-03 | 北京艺妙神州医药科技有限公司 | 慢病毒纯化工艺 |
| CN115747017B (zh) * | 2022-10-25 | 2023-06-09 | 上海华新生物高技术有限公司 | 一种腺病毒纯化装置 |
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| AU2004249199B2 (en) | 2003-06-18 | 2008-07-24 | Onyx Pharmaceuticals, Inc. | Method for purifying virus |
| AU2005214090B2 (en) | 2004-02-23 | 2008-09-11 | Crucell Holland B.V. | Virus purification methods |
-
2006
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- 2006-04-11 ES ES06724513.4T patent/ES2317517T5/es active Active
- 2006-04-11 EP EP06724513.4A patent/EP1869171B2/de active Active
- 2006-04-11 WO PCT/EP2006/003722 patent/WO2006108707A1/en not_active Ceased
- 2006-04-11 CN CN2006800118153A patent/CN101155915B/zh not_active Expired - Fee Related
- 2006-04-11 CA CA2602944A patent/CA2602944C/en active Active
- 2006-04-11 DE DE602006003420T patent/DE602006003420D1/de active Active
- 2006-04-11 DK DK06724513.4T patent/DK1869171T4/en active
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2006233800A1 (en) | 2006-10-19 |
| EP1869171B2 (de) | 2015-10-14 |
| CN101155915A (zh) | 2008-04-02 |
| CN101155915B (zh) | 2013-12-04 |
| WO2006108707A1 (en) | 2006-10-19 |
| US20090123989A1 (en) | 2009-05-14 |
| ES2317517T3 (es) | 2009-04-16 |
| DK1869171T4 (en) | 2016-01-18 |
| EP1869171A1 (de) | 2007-12-26 |
| AU2006233800B2 (en) | 2011-07-07 |
| DK1869171T3 (da) | 2009-02-16 |
| US8574595B2 (en) | 2013-11-05 |
| ES2317517T5 (es) | 2016-01-21 |
| CA2602944C (en) | 2015-08-11 |
| EP1869171B1 (de) | 2008-10-29 |
| CA2602944A1 (en) | 2006-10-19 |
| DE602006003420D1 (de) | 2008-12-11 |
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