ATE412737T1 - Virusreinigung mit ultrafiltration - Google Patents
Virusreinigung mit ultrafiltrationInfo
- Publication number
- ATE412737T1 ATE412737T1 AT06724513T AT06724513T ATE412737T1 AT E412737 T1 ATE412737 T1 AT E412737T1 AT 06724513 T AT06724513 T AT 06724513T AT 06724513 T AT06724513 T AT 06724513T AT E412737 T1 ATE412737 T1 AT E412737T1
- Authority
- AT
- Austria
- Prior art keywords
- ultrafiltration
- virus
- virus cleaning
- adenovirus
- cleaning
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 2
- 238000000108 ultra-filtration Methods 0.000 title abstract 2
- 238000004140 cleaning Methods 0.000 title 1
- 241000701161 unidentified adenovirus Species 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000012466 permeate Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000012465 retentate Substances 0.000 abstract 1
- 238000005199 ultracentrifugation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10051—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67006405P | 2005-04-11 | 2005-04-11 | |
| EP05102842 | 2005-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE412737T1 true ATE412737T1 (de) | 2008-11-15 |
Family
ID=36572264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06724513T ATE412737T1 (de) | 2005-04-11 | 2006-04-11 | Virusreinigung mit ultrafiltration |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8574595B2 (de) |
| EP (1) | EP1869171B2 (de) |
| CN (1) | CN101155915B (de) |
| AT (1) | ATE412737T1 (de) |
| AU (1) | AU2006233800B2 (de) |
| CA (1) | CA2602944C (de) |
| DE (1) | DE602006003420D1 (de) |
| DK (1) | DK1869171T4 (de) |
| ES (1) | ES2317517T5 (de) |
| WO (1) | WO2006108707A1 (de) |
Families Citing this family (64)
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| WO2007110409A1 (en) * | 2006-03-27 | 2007-10-04 | Crucell Holland B.V. | Compositions comprising a recombinant adenovirus and an adjuvant |
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| US20080131955A1 (en) * | 2006-11-30 | 2008-06-05 | Canon U.S. Life Sciences, Inc. | Method of Separating Target DNA from Mixed DNA |
| EP2195418B1 (de) * | 2007-10-02 | 2012-12-12 | PTC Phage Technology Center GmbH | Verfahren und system zur grosstechnischen aufreinigung von für eine bakteriophagentherapie vorgesehenen bakteriophagen |
| ATE525062T1 (de) * | 2007-12-28 | 2011-10-15 | Baxter Int | Gegendruckfiltration von proteinen |
| US10273502B2 (en) * | 2008-06-18 | 2019-04-30 | Oxford Biomedica (Uk) Limited | Virus purification |
| EA019928B1 (ru) | 2008-11-03 | 2014-07-30 | Круселл Холланд Б.В. | Способ получения аденовирусных векторов |
| FR2944292B1 (fr) | 2009-04-08 | 2013-08-23 | Sanofi Pasteur | Procede de purification du virus rabique |
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| MX2012004222A (es) | 2009-10-15 | 2012-06-08 | Crucell Holland Bv | Metodo para purificacion de particulas de adenovirus. |
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| SG184833A1 (en) | 2010-04-14 | 2012-11-29 | Emd Millipore Corp | Methods of producing high titer, high purity virus stocks and methods of use thereof |
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| EP2603234B1 (de) * | 2010-08-12 | 2017-06-28 | Yisheng Biopharma Holdings Ltd. | Verfahren zur reduktion von dna-unreinheiten bei viralen zusammensetzungen |
| CA2808556A1 (en) | 2010-09-20 | 2012-03-29 | Crucell Holland B.V. | Therapeutic vaccination against active tuberculosis |
| BR112013004582A2 (pt) | 2010-09-27 | 2016-09-06 | Crucell Holland Bv | método para induzir uma resposta imune em um sujeito contra um antígeno de um parasita que causa a malária |
| PL2697369T3 (pl) | 2011-03-25 | 2018-12-31 | F.Hoffmann-La Roche Ag | Nowe sposoby oczyszczania białek |
| KR102022952B1 (ko) * | 2011-08-05 | 2019-09-20 | 신라젠(주) | 백시니아 바이러스의 생산을 위한 방법 및 조성물 |
| CN102688485A (zh) * | 2011-09-16 | 2012-09-26 | 扬州优邦生物制药有限公司 | 一种猪细小病毒灭活疫苗的制备方法 |
| WO2013074501A1 (en) | 2011-11-14 | 2013-05-23 | Crucell Holland B.V. | Heterologous prime-boost immunization using measles virus-based vaccines |
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| US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| KR102044051B1 (ko) | 2012-03-12 | 2019-11-12 | 얀센 백신스 앤드 프리벤션 비.브이. | 터미널 말단이 변경된 재조합 아데노바이러스의 배치 |
| JP5845376B2 (ja) | 2012-03-22 | 2016-01-20 | クルセル ホランド ベー ヴェー | Rsvに対するワクチン |
| US9125870B2 (en) | 2012-03-22 | 2015-09-08 | Crucell Holland B.V. | Vaccine against RSV |
| CN103923883A (zh) * | 2013-01-16 | 2014-07-16 | 辽宁成大生物股份有限公司 | 一种流感病毒的浓缩、纯化方法 |
| PT2988780T (pt) | 2013-04-25 | 2019-03-25 | Janssen Vaccines & Prevention Bv | Polipeptídeos f de pré-fusão do rsv solúveis estabilizados |
| CN105408348B (zh) | 2013-06-17 | 2021-07-06 | 扬森疫苗与预防公司 | 稳定化的可溶性融合前rsv f多肽 |
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| CN103601793A (zh) * | 2013-10-23 | 2014-02-26 | 乾元浩生物股份有限公司 | 一种禽用疫苗抗原纯化的方法 |
| KR102707370B1 (ko) * | 2014-05-13 | 2024-09-13 | 암겐 인코포레이티드 | 필터 및 여과 공정과 함께 사용하기 위한 공정 제어 시스템 및 방법 |
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| AU2016289496B2 (en) | 2015-07-07 | 2021-02-04 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion RSV F polypeptides |
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| BR112018072865A2 (pt) | 2016-05-12 | 2019-04-30 | Janssen Vaccines & Prevention B.V. | promotor bidirecional potente e equilibrado |
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| JP6721797B2 (ja) | 2017-02-09 | 2020-07-15 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 異種遺伝子発現のための強力で短いプロモーター |
| JP7262449B2 (ja) * | 2017-05-15 | 2023-04-21 | シー‐レクタ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 酵素産物 |
| CA3061278A1 (en) | 2017-05-17 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
| CN107603959A (zh) * | 2017-08-30 | 2018-01-19 | 四川大学 | 提高缓冲液盐离子浓度纯化病毒的方法 |
| AU2018333566A1 (en) | 2017-09-15 | 2020-02-27 | Janssen Vaccines & Prevention B.V. | Method for the safe induction of immunity against RSV |
| GB201806736D0 (en) * | 2018-04-25 | 2018-06-06 | Ge Healthcare Bioprocess R&D Ab | Method for virus purification |
| PE20211469A1 (es) | 2018-11-13 | 2021-08-05 | Janssen Vaccines And Prevention B V | Proteinas f de prefusion del vrs estabilizadas |
| CN111454914A (zh) * | 2019-01-18 | 2020-07-28 | 嘉兴安宇生物科技有限公司 | 一种腺病毒快速纯化方法 |
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| CN110129287B (zh) * | 2019-05-15 | 2023-07-14 | 青岛蔚蓝生物制品有限公司 | 一种猪伪狂犬病毒双重超滤系统及纯化方法 |
| CN111394390A (zh) * | 2020-03-26 | 2020-07-10 | 赛诺(深圳)生物医药研究有限公司 | 用于新型冠状病毒基因疫苗的批量生产重组腺病毒的方法 |
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| EP3919613B1 (de) * | 2020-06-05 | 2024-08-07 | Sartorius BIA Separations d.o.o. | Verbesserte reinigung von adeno-assoziiertem virus um kontaminierende dna effektiver zu entfernen |
| CN112226418B (zh) * | 2020-09-25 | 2022-07-08 | 阜外华中心血管病医院 | 重组腺相关病毒纯化方法 |
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| US20030180936A1 (en) | 2002-03-15 | 2003-09-25 | Memarzadeh Bahram Eric | Method for the purification, production and formulation of oncolytic adenoviruses |
| JP2005521417A (ja) | 2002-03-29 | 2005-07-21 | メルク エンド カムパニー インコーポレーテッド | アデノウイルスの大規模産生方法及びアデノウイルス種子ストック |
| CA2478508C (en) | 2002-04-25 | 2013-07-02 | Crucell Holland B.V. | Stable adenoviral vectors and methods for propagation thereof |
| EP1506287B1 (de) * | 2002-05-14 | 2007-04-25 | Merck & Co., Inc. | Verfahren zur reinigung von adenovirus |
| US20050095705A1 (en) | 2003-04-15 | 2005-05-05 | Michael Kadan | Method for production of oncolytic adenoviruses |
| CA2529053A1 (en) * | 2003-06-18 | 2004-12-29 | Onyx Pharmaceuticals, Inc. | Method for purifying virus |
| CN1922308A (zh) * | 2004-02-23 | 2007-02-28 | 克鲁塞尔荷兰公司 | 病毒纯化方法 |
-
2006
- 2006-04-11 AT AT06724513T patent/ATE412737T1/de active
- 2006-04-11 WO PCT/EP2006/003722 patent/WO2006108707A1/en not_active Ceased
- 2006-04-11 CA CA2602944A patent/CA2602944C/en not_active Expired - Lifetime
- 2006-04-11 ES ES06724513.4T patent/ES2317517T5/es not_active Expired - Lifetime
- 2006-04-11 EP EP06724513.4A patent/EP1869171B2/de not_active Expired - Lifetime
- 2006-04-11 DE DE602006003420T patent/DE602006003420D1/de not_active Expired - Lifetime
- 2006-04-11 US US11/909,955 patent/US8574595B2/en not_active Expired - Fee Related
- 2006-04-11 CN CN2006800118153A patent/CN101155915B/zh not_active Expired - Fee Related
- 2006-04-11 AU AU2006233800A patent/AU2006233800B2/en not_active Ceased
- 2006-04-11 DK DK06724513.4T patent/DK1869171T4/en active
Also Published As
| Publication number | Publication date |
|---|---|
| DK1869171T3 (da) | 2009-02-16 |
| CN101155915B (zh) | 2013-12-04 |
| AU2006233800A1 (en) | 2006-10-19 |
| DE602006003420D1 (de) | 2008-12-11 |
| ES2317517T5 (es) | 2016-01-21 |
| CA2602944A1 (en) | 2006-10-19 |
| DK1869171T4 (en) | 2016-01-18 |
| US8574595B2 (en) | 2013-11-05 |
| CA2602944C (en) | 2015-08-11 |
| CN101155915A (zh) | 2008-04-02 |
| EP1869171B2 (de) | 2015-10-14 |
| EP1869171B1 (de) | 2008-10-29 |
| AU2006233800B2 (en) | 2011-07-07 |
| US20090123989A1 (en) | 2009-05-14 |
| ES2317517T3 (es) | 2009-04-16 |
| WO2006108707A1 (en) | 2006-10-19 |
| EP1869171A1 (de) | 2007-12-26 |
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