ATE346165T1 - Verfahren zur trennung und/oder erkennung von dns-molekülen - Google Patents

Verfahren zur trennung und/oder erkennung von dns-molekülen

Info

Publication number
ATE346165T1
ATE346165T1 AT96940034T AT96940034T ATE346165T1 AT E346165 T1 ATE346165 T1 AT E346165T1 AT 96940034 T AT96940034 T AT 96940034T AT 96940034 T AT96940034 T AT 96940034T AT E346165 T1 ATE346165 T1 AT E346165T1
Authority
AT
Austria
Prior art keywords
dna molecules
duplexes
separating
mixture
detecting dna
Prior art date
Application number
AT96940034T
Other languages
English (en)
Inventor
Rafael Anthony Arguello
Alejandro Madrigal
Original Assignee
Anthony Nolan Bone Marrow Trus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9524379.6A external-priority patent/GB9524379D0/en
Priority claimed from GBGB9600304.1A external-priority patent/GB9600304D0/en
Priority claimed from GBGB9609823.1A external-priority patent/GB9609823D0/en
Application filed by Anthony Nolan Bone Marrow Trus filed Critical Anthony Nolan Bone Marrow Trus
Application granted granted Critical
Publication of ATE346165T1 publication Critical patent/ATE346165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT96940034T 1995-11-29 1996-11-29 Verfahren zur trennung und/oder erkennung von dns-molekülen ATE346165T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9524379.6A GB9524379D0 (en) 1995-11-29 1995-11-29 Methods for separating and identifying DNA molecules
GBGB9600304.1A GB9600304D0 (en) 1996-01-08 1996-01-08 Methods for separating and identifying DNA molecules
GBGB9609823.1A GB9609823D0 (en) 1996-05-10 1996-05-10 Methods for separating and identifying DNA molecules

Publications (1)

Publication Number Publication Date
ATE346165T1 true ATE346165T1 (de) 2006-12-15

Family

ID=27268001

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96940034T ATE346165T1 (de) 1995-11-29 1996-11-29 Verfahren zur trennung und/oder erkennung von dns-molekülen

Country Status (6)

Country Link
US (1) US6994958B2 (de)
EP (1) EP0876508B1 (de)
AT (1) ATE346165T1 (de)
AU (1) AU7703896A (de)
DE (1) DE69636725T2 (de)
WO (1) WO1997020070A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999007883A1 (en) * 1997-08-11 1999-02-18 Visible Genetics Inc. Method and kit for hla class i typing dna
EP0953650A1 (de) * 1998-04-20 1999-11-03 Innogenetics N.V. Verfahren für die HLA Typisierung
FR2793809B1 (fr) * 1999-05-20 2006-07-28 Biomerieux Sa Procede d'analyse de la predisposition genetique d'un patient a au moins une maladie et amplification adaptee a un tel procede
US20080113445A1 (en) * 2006-11-02 2008-05-15 Abraham Yaniv Non-metallic laboratory implement and method of its use
JP7048105B2 (ja) 2016-07-15 2022-04-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 核酸ライブラリを生成する方法
AU2019207900B2 (en) 2018-01-12 2025-07-10 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
WO2019236726A1 (en) 2018-06-06 2019-12-12 The Regents Of The University Of California Methods of producing nucleic acid libraries and compositions and kits for practicing same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387505A (en) * 1990-05-04 1995-02-07 Eastman Kodak Company Preparation and isolation of single-stranded biotinylated nucleic acids by heat avidin-biotin cleavage
US5702885A (en) * 1990-06-27 1997-12-30 The Blood Center Research Foundation, Inc. Method for HLA typing
AU2491692A (en) 1991-08-29 1993-04-05 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The A method for discriminating and identifying alleles in complex loci
ZA929351B (en) * 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
GB9206567D0 (en) 1992-03-25 1992-05-06 Univ Bristol Dna analysis
EP0575845A3 (de) * 1992-06-23 1998-01-07 F. Hoffmann-La Roche Ag Verfahren für Charakterisierung von HLA-DP
WO1995001453A1 (en) * 1993-07-01 1995-01-12 The Board Of Trustees Of The Leland Stanford Junior University A heteroduplex mobility assay for the analysis of nucleic acid sequence diversity
KR970007025B1 (ko) * 1993-08-28 1997-05-02 정연보 잡종화에 의한 대립연쇄반복 dna의 동정방법

Also Published As

Publication number Publication date
DE69636725D1 (de) 2007-01-04
DE69636725T2 (de) 2007-09-20
EP0876508B1 (de) 2006-11-22
EP0876508A1 (de) 1998-11-11
US20030104363A1 (en) 2003-06-05
AU7703896A (en) 1997-06-19
US6994958B2 (en) 2006-02-07
WO1997020070A1 (en) 1997-06-05

Similar Documents

Publication Publication Date Title
EP1961826A3 (de) Verfahren zur direkten Sequenzierung von Nukleinsäuren
ATE210192T1 (de) VERFAHREN ZUR DIREKTEN SEQUENZIERUNG WÄHREND ßTEMPLATEß-AMPLIFIKATION
ATE191934T1 (de) Verfahren zur isothermer amplifikation von nukleinsäure molekülen
DE69232677D1 (de) Verfahren zur Trennung doppelsträngiger DNA von einzelsträngiger DNA oder RNA
DE3687287D1 (de) Verfahren zur amplifikation von nukleinsaeuresequenzen.
DE69837913D1 (de) Verfahren zur vervielfältigung von nukleinsäure
BR9407712A (pt) Métodos e composiçoes para sequenciamento eficaz de ácidos nuclêicos
EP0777750A4 (de) Verfahren mit einer hohen umsatzrate für das auffinden von sequenzen oder genetischen veränderungen in nukleinsäuren
DE69329636D1 (de) Verfahren zur Vervielfältigung von Nukleinsäuresequenzen
DE69132098D1 (de) Verfahren zur amplifikation von nukleinsäuren
ATE470712T1 (de) Nukleinsäureliganden mit hoher affinität zu dem c5-protein des komplementsystems
ATE343638T1 (de) Oligonukleotidliganden mit hoher affinität für pdgf
ATE419388T1 (de) Nukleinsäureanreicherung
DE69432419D1 (de) Ein elektrochemiluminescenter nachweis von nukleinsäuren auf basis der selbsttragenden sequenzreplikation
DE60035691D1 (de) Verfahren zur Erkennung von Einzel-Nukleotid-Polymorphismen
ATE255168T1 (de) Massenspektroskopische verfahren zur sequenzierung von nukleinsäuren
ATE230034T1 (de) Verfahren zur aufreinigung von dns
ATA183094A (de) Verfahren zur quantifizierung von genomischer dna
ATE278785T1 (de) Neues verfahren zur gewinnung und reinigung von fusionsproteinen
ATE212382T1 (de) Verfahren zur sequenzierung durch oligomerhybridisierung
ATE247175T1 (de) Methode zur eliminierung von sequenzierartefakten
DE69636725D1 (de) Verfahren zur trennung und/oder erkennung von dns-molekülen
DE69604051D1 (de) Verfahren zum sensitiven nachweis von reverser transcriptase
DE69711073D1 (de) Verfahren zur erkennung von lebenden mikrobiologischen verunreinigungen in einer lebensmittelprobe
WO1998026091A3 (en) Method and kit for HLA class I typing

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties