ATE346165T1 - Verfahren zur trennung und/oder erkennung von dns-molekülen - Google Patents

Verfahren zur trennung und/oder erkennung von dns-molekülen

Info

Publication number
ATE346165T1
ATE346165T1 AT96940034T AT96940034T ATE346165T1 AT E346165 T1 ATE346165 T1 AT E346165T1 AT 96940034 T AT96940034 T AT 96940034T AT 96940034 T AT96940034 T AT 96940034T AT E346165 T1 ATE346165 T1 AT E346165T1
Authority
AT
Austria
Prior art keywords
dna molecules
duplexes
separating
mixture
detecting dna
Prior art date
Application number
AT96940034T
Other languages
English (en)
Inventor
Rafael Anthony Arguello
Alejandro Madrigal
Original Assignee
Anthony Nolan Bone Marrow Trus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9524379.6A external-priority patent/GB9524379D0/en
Priority claimed from GBGB9600304.1A external-priority patent/GB9600304D0/en
Priority claimed from GBGB9609823.1A external-priority patent/GB9609823D0/en
Application filed by Anthony Nolan Bone Marrow Trus filed Critical Anthony Nolan Bone Marrow Trus
Application granted granted Critical
Publication of ATE346165T1 publication Critical patent/ATE346165T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT96940034T 1995-11-29 1996-11-29 Verfahren zur trennung und/oder erkennung von dns-molekülen ATE346165T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9524379.6A GB9524379D0 (en) 1995-11-29 1995-11-29 Methods for separating and identifying DNA molecules
GBGB9600304.1A GB9600304D0 (en) 1996-01-08 1996-01-08 Methods for separating and identifying DNA molecules
GBGB9609823.1A GB9609823D0 (en) 1996-05-10 1996-05-10 Methods for separating and identifying DNA molecules

Publications (1)

Publication Number Publication Date
ATE346165T1 true ATE346165T1 (de) 2006-12-15

Family

ID=27268001

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96940034T ATE346165T1 (de) 1995-11-29 1996-11-29 Verfahren zur trennung und/oder erkennung von dns-molekülen

Country Status (6)

Country Link
US (1) US6994958B2 (de)
EP (1) EP0876508B1 (de)
AT (1) ATE346165T1 (de)
AU (1) AU7703896A (de)
DE (1) DE69636725T2 (de)
WO (1) WO1997020070A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001512694A (ja) * 1997-08-11 2001-08-28 ビジブル・ジェネティクス・インコーポレーテッド Dnaのhlaクラスiタイプを決定するための方法およびキット
EP0953650A1 (de) * 1998-04-20 1999-11-03 Innogenetics N.V. Verfahren für die HLA Typisierung
FR2793809B1 (fr) 1999-05-20 2006-07-28 Biomerieux Sa Procede d'analyse de la predisposition genetique d'un patient a au moins une maladie et amplification adaptee a un tel procede
US20080113445A1 (en) * 2006-11-02 2008-05-15 Abraham Yaniv Non-metallic laboratory implement and method of its use
CN109563543B (zh) 2016-07-15 2022-08-30 加利福尼亚大学董事会 产生核酸库的方法
JP7296969B2 (ja) 2018-01-12 2023-06-23 クラレット バイオサイエンス, エルエルシー 核酸を解析するための方法および組成物
EP3802864A1 (de) 2018-06-06 2021-04-14 The Regents Of The University Of California Verfahren zur herstellung von nukleinsäurebibliotheken und zusammensetzungen und kits zur durchführung davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387505A (en) * 1990-05-04 1995-02-07 Eastman Kodak Company Preparation and isolation of single-stranded biotinylated nucleic acids by heat avidin-biotin cleavage
US5702885A (en) 1990-06-27 1997-12-30 The Blood Center Research Foundation, Inc. Method for HLA typing
WO1993005179A1 (en) 1991-08-29 1993-03-18 THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES:National Institutes of Health A method for discriminating and identifying alleles in complex loci
ZA929351B (en) * 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
GB9206567D0 (en) 1992-03-25 1992-05-06 Univ Bristol Dna analysis
EP0575845A3 (de) * 1992-06-23 1998-01-07 F. Hoffmann-La Roche Ag Verfahren für Charakterisierung von HLA-DP
WO1995001453A1 (en) * 1993-07-01 1995-01-12 The Board Of Trustees Of The Leland Stanford Junior University A heteroduplex mobility assay for the analysis of nucleic acid sequence diversity
KR970007025B1 (ko) * 1993-08-28 1997-05-02 정연보 잡종화에 의한 대립연쇄반복 dna의 동정방법

Also Published As

Publication number Publication date
EP0876508A1 (de) 1998-11-11
WO1997020070A1 (en) 1997-06-05
US6994958B2 (en) 2006-02-07
DE69636725D1 (de) 2007-01-04
AU7703896A (en) 1997-06-19
EP0876508B1 (de) 2006-11-22
DE69636725T2 (de) 2007-09-20
US20030104363A1 (en) 2003-06-05

Similar Documents

Publication Publication Date Title
EP1961826A3 (de) Verfahren zur direkten Sequenzierung von Nukleinsäuren
ATE210192T1 (de) VERFAHREN ZUR DIREKTEN SEQUENZIERUNG WÄHREND ßTEMPLATEß-AMPLIFIKATION
ATE191934T1 (de) Verfahren zur isothermer amplifikation von nukleinsäure molekülen
DE69433487D1 (de) Methoden und zusammensetzungen zur effizienten nukleinsaeuresequenzierung
DE69232677D1 (de) Verfahren zur Trennung doppelsträngiger DNA von einzelsträngiger DNA oder RNA
DE3687287D1 (de) Verfahren zur amplifikation von nukleinsaeuresequenzen.
DE69837913D1 (de) Verfahren zur vervielfältigung von nukleinsäure
ATE191513T1 (de) Verfahren zur amplifikation von nukleinsäuren
ATE470712T1 (de) Nukleinsäureliganden mit hoher affinität zu dem c5-protein des komplementsystems
DE69636656D1 (de) Oligonukleotidliganden mit hoher affinität für pdgf
ATE419388T1 (de) Nukleinsäureanreicherung
ATE255168T1 (de) Massenspektroskopische verfahren zur sequenzierung von nukleinsäuren
ATE197479T1 (de) Verfahren zur vervielfältigung von nukleinsäuresequenzen
DE69531831D1 (de) Verfahren mit einer hohen umsatzrate für das auffinden von sequenzen oder genetischen veränderungen in nukleinsäuren
DE59908447D1 (de) Verfahren zur Herstellung von hantelförmigen DNA-Molekülen als Expressionskonstrukte
DE69718054D1 (de) Verfahren zur aufreinigung von dns
ATA183094A (de) Verfahren zur quantifizierung von genomischer dna
ATE278785T1 (de) Neues verfahren zur gewinnung und reinigung von fusionsproteinen
ATE212382T1 (de) Verfahren zur sequenzierung durch oligomerhybridisierung
ATE247175T1 (de) Methode zur eliminierung von sequenzierartefakten
ATE346165T1 (de) Verfahren zur trennung und/oder erkennung von dns-molekülen
DE69711073D1 (de) Verfahren zur erkennung von lebenden mikrobiologischen verunreinigungen in einer lebensmittelprobe
DE60119173D1 (de) Methode zur analyse von oligonukleotidanaloga
WO1998026091A3 (en) Method and kit for HLA class I typing
DE50208262D1 (de) Verfahren zur bestimmung von flüchtigen substanzen in lösung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties