ATE348176T1 - Komplex aus peptid und mhc-peptid auf oberfläche von phagen - Google Patents

Komplex aus peptid und mhc-peptid auf oberfläche von phagen

Info

Publication number
ATE348176T1
ATE348176T1 AT99918065T AT99918065T ATE348176T1 AT E348176 T1 ATE348176 T1 AT E348176T1 AT 99918065 T AT99918065 T AT 99918065T AT 99918065 T AT99918065 T AT 99918065T AT E348176 T1 ATE348176 T1 AT E348176T1
Authority
AT
Austria
Prior art keywords
peptide
complex
mhc
concerns
micro
Prior art date
Application number
AT99918065T
Other languages
English (en)
Inventor
Guy Gorochov
Bernard Piqueras
Doussal Jean-Marc Le
Patrice Debre
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE348176T1 publication Critical patent/ATE348176T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14111—Inoviridae
    • C12N2795/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Paints Or Removers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT99918065T 1998-05-14 1999-05-12 Komplex aus peptid und mhc-peptid auf oberfläche von phagen ATE348176T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9806213A FR2778669B1 (fr) 1998-05-14 1998-05-14 Procede d'expression d'un complexe forme d'au moins un produit du complexe majeur d'histocompatibilite et d'un peptide chez un phage, phages et complexes ainsi obtenus et leurs applications

Publications (1)

Publication Number Publication Date
ATE348176T1 true ATE348176T1 (de) 2007-01-15

Family

ID=9526436

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99918065T ATE348176T1 (de) 1998-05-14 1999-05-12 Komplex aus peptid und mhc-peptid auf oberfläche von phagen

Country Status (8)

Country Link
EP (1) EP1078078B1 (de)
JP (1) JP2002514431A (de)
AT (1) ATE348176T1 (de)
AU (1) AU3612099A (de)
CA (1) CA2331061A1 (de)
DE (1) DE69934399D1 (de)
FR (1) FR2778669B1 (de)
WO (1) WO1999058693A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1118661A1 (de) * 2000-01-13 2001-07-25 Het Nederlands Kanker Instituut T-Zellrezeptor-Bibliotheken
US6800463B1 (en) 2000-04-20 2004-10-05 Virco Bvba Method for mutation detection in HIV-1 using pol sequencing
AU2001256318B8 (en) * 2000-04-20 2007-03-22 Virco Bvba Method for mutation detection in HIV using pol sequencing
US20020165149A1 (en) * 2000-12-08 2002-11-07 Kranz David M. Mutated class II major histocompatibility proteins
GB0110547D0 (en) * 2001-04-30 2001-06-20 Avidex Ltd Method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658197B1 (fr) * 1990-02-14 1992-05-22 Inst Nat Sante Rech Med Anticorps monoclonaux restreints reconnaissant un peptide associe a un antigene du complexe majeur d'histocompatibilite - applications au diagnostic et au traitement.
US5734023A (en) * 1991-11-19 1998-03-31 Anergen Inc. MHC class II β chain/peptide complexes useful in ameliorating deleterious immune responses
US8211422B2 (en) * 1992-03-18 2012-07-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric receptor genes and cells transformed therewith
DE4224542A1 (de) * 1992-07-24 1994-01-27 Deutsches Krebsforsch Verfahren zur Herstellung von monoklonalen MHC Klasse I-puls-Peptid-restringierten Antikörpern
WO1996004314A1 (en) * 1994-07-29 1996-02-15 Dade International, Inc. Mhc complexes and uses thereof
CA2224205A1 (en) * 1995-06-07 1996-12-19 Zymogenetics, Inc. Fused soluble mhc heterodimer-peptide complexes and their uses
JPH11510375A (ja) * 1995-06-30 1999-09-14 コベンハブンズ ユニバーサイテッド ペプチド−ｍｈｃ複合体を指向するファージディスプレイライブラリーからの組換え抗体
US6056952A (en) * 1995-08-30 2000-05-02 The United States Of America As Represented By The Department Of Health And Human Services Selective elimination of T cells that recognize specific preselected targets
US6211342B1 (en) * 1996-07-18 2001-04-03 Children's Hospital Medical Center Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function
JP2000516470A (ja) * 1996-08-16 2000-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ 可溶性一価および多価ｍｈｃクラスｉｉ融合タンパク質およびそれらの使用

Also Published As

Publication number Publication date
CA2331061A1 (fr) 1999-11-18
FR2778669B1 (fr) 2002-06-14
FR2778669A1 (fr) 1999-11-19
AU3612099A (en) 1999-11-29
DE69934399D1 (de) 2007-01-25
JP2002514431A (ja) 2002-05-21
EP1078078B1 (de) 2006-12-13
EP1078078A1 (de) 2001-02-28
WO1999058693A1 (fr) 1999-11-18

Similar Documents

Publication Publication Date Title
IL143243A0 (en) A cultured tissue construct containing fibroblast cells and methods for the production thereof
ATE368054T1 (de) Verbindungen und methoden zur modulierung von occludin-abhängiger gewebepermeabilität
PT1053256E (pt) Anticorpos para o receptor de morte 4 (dr4) e utilizações destes
TW428026B (en) Bifunctional protein, preparation and use
IL117425A0 (en) Receptor activation by gas6
TR199902426T2 (xx) Bitki b�ceklerinin kontrol�.
ATE295416T1 (de) Humanisiertes grünes-fluoreszenzprotein und methoden
ES2151921T3 (es) Analogo de dolastatina.
CA2413156A1 (en) Expression vectors
NO20030856L (no) Membranpenetrerende peptider og anvendelse av disse
NO980976D0 (no) Materialer og fremgangsmåter for å feste og fremvise stoffer på celleoverflater
WO2006127809A3 (en) Methods for expansion and analysis of cultured hematopoietic stem cells
ATE324030T1 (de) Brassica-transformation durch teilchenbeschuss
FR2662698B1 (de)
DE69631972D1 (de) Proliferationsinhibitor von endothellzellen und dessen verwendung
EP1135531A4 (de) Methoden zur introduktion heterologer zellen in fische
ATE348176T1 (de) Komplex aus peptid und mhc-peptid auf oberfläche von phagen
EP2311960A3 (de) Bv8-Nukleinsäuren und Polypeptide mit mitogener Aktivität
CA2318432A1 (en) The use of isolated domains of type iv collagen to modify cell and tissue interactions
DK0939769T3 (da) Vertebrat-Smoothened-proteiner
GB2379446A (en) Cells,culture methods and their uses
DE69737597D1 (de) Vektoren zur inhibierung von viralem und tumorwachstum
DE69838615D1 (de) ppGpp-SYNTHETASE UND EXPRESSIONSSYSTEME ZUR VERBESSERTEN HERSTELLUNG VON PROTEINEN
DE60132466D1 (de) Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen
ATE175122T1 (de) Endothelzell-ligand für den leukocyten cr3 erkennender antikörper

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties