ATE351911T1 - Verfahren zur herstellung von heterologen proteinen in fungi - Google Patents

Verfahren zur herstellung von heterologen proteinen in fungi

Info

Publication number
ATE351911T1
ATE351911T1 AT01270616T AT01270616T ATE351911T1 AT E351911 T1 ATE351911 T1 AT E351911T1 AT 01270616 T AT01270616 T AT 01270616T AT 01270616 T AT01270616 T AT 01270616T AT E351911 T1 ATE351911 T1 AT E351911T1
Authority
AT
Austria
Prior art keywords
heterologue
fungi
proteins
producing
inducer
Prior art date
Application number
AT01270616T
Other languages
English (en)
Inventor
De Laar Antonius M J Van
Nigel M Lindner
Peter Nieuwpoort
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Application granted granted Critical
Publication of ATE351911T1 publication Critical patent/ATE351911T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
AT01270616T 2000-12-13 2001-11-16 Verfahren zur herstellung von heterologen proteinen in fungi ATE351911T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00311095 2000-12-13

Publications (1)

Publication Number Publication Date
ATE351911T1 true ATE351911T1 (de) 2007-02-15

Family

ID=8173440

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01270616T ATE351911T1 (de) 2000-12-13 2001-11-16 Verfahren zur herstellung von heterologen proteinen in fungi

Country Status (18)

Country Link
US (1) US7560249B2 (de)
EP (1) EP1349945B1 (de)
JP (1) JP4494716B2 (de)
CN (1) CN1481439A (de)
AT (1) ATE351911T1 (de)
AU (2) AU1604902A (de)
BR (1) BR0116675A (de)
CA (1) CA2427665C (de)
CZ (1) CZ303983B6 (de)
DE (1) DE60126148T2 (de)
ES (1) ES2278681T3 (de)
HU (1) HU228689B1 (de)
IL (1) IL156438A0 (de)
MX (1) MXPA03005358A (de)
PL (1) PL204737B1 (de)
SK (1) SK287621B6 (de)
WO (1) WO2002048382A2 (de)
ZA (1) ZA200303353B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008079228A1 (en) * 2006-12-20 2008-07-03 Danisco Us, Inc., Genencor Division Assays for improved fungal strains
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
AU2016273912B2 (en) * 2011-05-20 2018-08-02 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
MX368546B (es) * 2011-05-20 2019-10-07 Alderbio Holdings Llc Producción en alta pureza de proteínas multi-subunitarias tales como anticuerpos en microbios transformados tal como pichia pastoris.
US10150968B2 (en) 2011-08-19 2018-12-11 Alderbio Holdings Llc Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US20140273094A1 (en) 2013-03-15 2014-09-18 Bristol-Myers Squibb Company Methods of enhancing protein quality and quantity by yeast fed-batch fermentation
CN105960451A (zh) * 2013-09-19 2016-09-21 纽约城市大学研究基金 用于增加酵母生物量的方法
WO2016156474A1 (en) 2015-03-31 2016-10-06 Vhsquared Limited Polypeptide comprising an immunoglobulin chain variable domain which binds to clostridium difficile toxin a
WO2016156468A1 (en) 2015-03-31 2016-10-06 Vhsquared Limited Polypeptides
SG11201706840WA (en) 2015-03-31 2017-09-28 Vhsquared Ltd Peptide construct having a protease-cleavable linker
EP3277706A1 (de) 2015-03-31 2018-02-07 VHsquared Limited Polypeptid mit immunglobulinkettenvariabler domäne mit bindung an clostridium-difficile-toxin b
CA3255406A1 (en) 2015-03-31 2025-07-03 Sorriso Pharmaceuticals, Inc. Tnf-alpha binding polypeptides
EP3519438A1 (de) 2016-09-30 2019-08-07 VHsquared Limited Zusammensetzungen
KR20220063148A (ko) 2019-06-21 2022-05-17 소리소 파마슈티컬스 인크. 조성물
US12559552B2 (en) 2019-06-21 2026-02-24 Sorriso Pharmaceuticals, Inc. IL-23 and TNF-alpha binding bi-specific heavy chain polypeptides
CA3144567A1 (en) 2019-06-21 2020-12-24 Scott Crowe Polypeptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991000920A2 (en) 1989-07-07 1991-01-24 Unilever N.V. Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector
CN1149285C (zh) 1995-07-05 2004-05-12 尤尼利弗公司 在可食用生物中表达海洋鱼类的抗冻肽以及其在食品生产中的应用
ES2324280T3 (es) 2000-03-14 2009-08-04 Unilever N.V. Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos.

Also Published As

Publication number Publication date
SK7402003A3 (en) 2003-09-11
BR0116675A (pt) 2003-11-04
EP1349945B1 (de) 2007-01-17
HUP0302655A2 (hu) 2003-11-28
EP1349945A2 (de) 2003-10-08
CZ20031659A3 (cs) 2003-11-12
JP4494716B2 (ja) 2010-06-30
CA2427665A1 (en) 2002-06-20
WO2002048382A2 (en) 2002-06-20
IL156438A0 (en) 2004-01-04
PL204737B1 (pl) 2010-02-26
CA2427665C (en) 2011-10-11
US7560249B2 (en) 2009-07-14
HU228689B1 (hu) 2013-05-28
CN1481439A (zh) 2004-03-10
DE60126148D1 (de) 2007-03-08
HUP0302655A3 (en) 2004-10-28
WO2002048382A3 (en) 2003-01-30
MXPA03005358A (es) 2003-10-06
AU1604902A (en) 2002-06-24
ZA200303353B (en) 2004-04-30
SK287621B6 (sk) 2011-04-05
ES2278681T3 (es) 2007-08-16
DE60126148T2 (de) 2007-05-31
PL362773A1 (en) 2004-11-02
JP2004515249A (ja) 2004-05-27
US20040077069A1 (en) 2004-04-22
CZ303983B6 (cs) 2013-07-31
AU2002216049B2 (en) 2005-11-24

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