ATE354097T1 - Verfahren zur diagnose von leberfibrose. - Google Patents
Verfahren zur diagnose von leberfibrose.Info
- Publication number
- ATE354097T1 ATE354097T1 AT04025621T AT04025621T ATE354097T1 AT E354097 T1 ATE354097 T1 AT E354097T1 AT 04025621 T AT04025621 T AT 04025621T AT 04025621 T AT04025621 T AT 04025621T AT E354097 T1 ATE354097 T1 AT E354097T1
- Authority
- AT
- Austria
- Prior art keywords
- liver fibrosis
- severity
- optionally
- measuring
- diagnosis
- Prior art date
Links
- 208000019425 cirrhosis of liver Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title 1
- 208000019423 liver disease Diseases 0.000 abstract 2
- 102100027378 Prothrombin Human genes 0.000 abstract 1
- 108010094028 Prothrombin Proteins 0.000 abstract 1
- 102000005876 Tissue Inhibitor of Metalloproteinases Human genes 0.000 abstract 1
- 108010005246 Tissue Inhibitor of Metalloproteinases Proteins 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 229940039716 prothrombin Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/08—Hepato-biliairy disorders other than hepatitis
- G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04019134 | 2004-08-12 | ||
| EP04025621A EP1626280B1 (de) | 2004-08-12 | 2004-10-28 | Verfahren zur Diagnose von Leberfibrose. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE354097T1 true ATE354097T1 (de) | 2007-03-15 |
Family
ID=34981126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04025621T ATE354097T1 (de) | 2004-08-12 | 2004-10-28 | Verfahren zur diagnose von leberfibrose. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20070178443A1 (de) |
| EP (1) | EP1626280B1 (de) |
| JP (1) | JP4516124B2 (de) |
| CN (1) | CN101023356A (de) |
| AT (1) | ATE354097T1 (de) |
| CA (1) | CA2575475C (de) |
| DE (1) | DE602004004775T2 (de) |
| ES (1) | ES2282780T3 (de) |
| WO (1) | WO2006015874A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100999720B1 (ko) | 2008-11-13 | 2010-12-08 | 아주대학교산학협력단 | 간 경변 진단을 위한 분석방법 |
| CN102265160B (zh) * | 2008-12-24 | 2014-07-23 | 学校法人庆应义塾 | 肝病标记物、其测定方法、装置和医药品的检验方法 |
| KR101018960B1 (ko) | 2009-02-23 | 2011-03-02 | 아주대학교산학협력단 | 유의성있는 간섬유화 진단을 위한 분석 방법 |
| US9585613B2 (en) * | 2009-02-26 | 2017-03-07 | Universite D'angers | Diagnosis of liver fibrosis and cirrhosis |
| CN102439456B (zh) * | 2009-03-19 | 2016-11-02 | 昂热大学 | 用于评估肝纤维化进展的非侵入方法 |
| CN102460174B (zh) * | 2009-05-14 | 2016-03-16 | 牛津大学之校长及学者 | 使用一组新型低丰度人类血浆蛋白生物标记对肝纤维化进行临床诊断 |
| EP2327988A1 (de) | 2009-11-28 | 2011-06-01 | Assistance Publique Hôpitaux De Paris | Verfahren zur Diagnose von fibrotischen Erkrankungen |
| WO2012006512A1 (en) * | 2010-07-08 | 2012-01-12 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Adenovirus ad36 e4orf1 protein for prevention and treatment of non-alcoholic fatty liver disease |
| CN102302358B (zh) * | 2011-06-29 | 2014-04-09 | 内蒙古福瑞医疗科技股份有限公司 | 肝纤维化检测系统 |
| WO2013000246A1 (zh) * | 2011-06-29 | 2013-01-03 | 内蒙古福瑞中蒙药科技股份有限公司 | 肝纤维化检测设备和系统 |
| CN102636642B (zh) * | 2012-04-06 | 2014-04-30 | 中国人民解放军第三0二医院 | 一种肝纤维化诊断的快速定量试纸条的制备方法 |
| ES2523903B1 (es) * | 2013-04-30 | 2015-09-09 | Fundación Pública Andaluza Progreso Y Salud | Método de obtención de datos útiles para el diagnóstico diferencial de la fibrosis hepática |
| BR112016002247A2 (pt) * | 2013-08-02 | 2017-08-01 | Echosens | sistema não invasivo para o cálculo de um resultado confiável, padronizado e completo em ser humano ou animal |
| MX367294B (es) * | 2013-09-24 | 2019-08-05 | Univ Mexico Nac Autonoma | Prueba in vitro para diagnostico temprano y estadificacion de fibrosis hepatica. |
| MX356444B (es) * | 2013-09-24 | 2018-05-21 | Univ Mexico Nac Autonoma | Arreglo múltiple de anticuerpos específicos para el pronóstico, detección y vigilancia del proceso fibrogénico. |
| EP3491388B1 (de) * | 2016-08-01 | 2021-09-01 | Centre Hospitalier Universitaire d'Angers | Multi-zielgerichteten fibrosetests |
| WO2019191059A1 (en) * | 2018-03-26 | 2019-10-03 | The General Hospital Corporation | Method for objective, noninvasive staging of diffuse liver disease from ultrasound shear-wave elastography |
| CN110070942A (zh) * | 2019-04-22 | 2019-07-30 | 深圳市绘云生物科技有限公司 | 一种基于梯度提升树模型的慢性肝病风险评估系统 |
| CN114550942B (zh) * | 2022-02-16 | 2023-06-30 | 四川大学华西医院 | 一种肝脏显著纤维化预测模型及构建方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0823558B2 (ja) * | 1984-11-27 | 1996-03-06 | オ−ジエニクス リミテツド | 検定装置 |
| GB8803000D0 (en) * | 1988-02-10 | 1988-03-09 | Ekins Roger Philip | Determination of ambient concentrations of several analytes |
| ATE161964T1 (de) * | 1991-10-15 | 1998-01-15 | Multilyte Ltd | Bindungstest unter benutzung eines markierten reagens |
| DE69832628T2 (de) * | 1997-04-23 | 2006-09-07 | Instrumentation Laboratory S.P.A. | Rekombinant-kaninchengewebefaktor basiertes prothrombinzeitreagenz |
| DE19731465A1 (de) * | 1997-07-22 | 1999-01-28 | Boehringer Mannheim Gmbh | Verwendung von Kontrollflächen zur Detektion von Störproben in einem Nachweisverfahren |
| US7141380B2 (en) * | 2000-04-28 | 2006-11-28 | Michael Volker | Assessment of liver fibrosis scoring with serum marker algorithms |
| EP1150123B1 (de) * | 2000-04-28 | 2006-07-12 | Bayer Aktiengesellschaft | Diagnose von Leberfibrose mit Hilfe von Serummarkeralgorithmen |
| US6631330B1 (en) * | 2000-08-21 | 2003-10-07 | Assistance Publique-Hopitaux De Paris (Ap-Hp) | Diagnosis method of inflammatory, fibrotic or cancerous disease using biochemical markers |
| DE60026337T2 (de) * | 2000-08-21 | 2007-01-11 | Assistance Publique, Hopitaux De Paris | Verfahren zur diagnose von leberkrankheit unter verwendung von biochemischen merkmalen |
| US6986995B2 (en) * | 2002-02-28 | 2006-01-17 | Prometheus Laboratories, Inc. | Methods of diagnosing liver fibrosis |
-
2004
- 2004-10-28 ES ES04025621T patent/ES2282780T3/es not_active Expired - Lifetime
- 2004-10-28 AT AT04025621T patent/ATE354097T1/de active
- 2004-10-28 DE DE602004004775T patent/DE602004004775T2/de not_active Expired - Lifetime
- 2004-10-28 EP EP04025621A patent/EP1626280B1/de not_active Expired - Lifetime
-
2005
- 2005-08-12 WO PCT/EP2005/008778 patent/WO2006015874A2/en not_active Ceased
- 2005-08-12 JP JP2007525265A patent/JP4516124B2/ja not_active Expired - Fee Related
- 2005-08-12 CN CNA2005800273192A patent/CN101023356A/zh active Pending
- 2005-08-12 CA CA2575475A patent/CA2575475C/en not_active Expired - Fee Related
-
2007
- 2007-02-09 US US11/673,072 patent/US20070178443A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006015874A3 (en) | 2006-09-28 |
| DE602004004775T2 (de) | 2007-11-22 |
| ES2282780T3 (es) | 2007-10-16 |
| DE602004004775D1 (de) | 2007-03-29 |
| CA2575475C (en) | 2010-03-30 |
| EP1626280A1 (de) | 2006-02-15 |
| CN101023356A (zh) | 2007-08-22 |
| WO2006015874A2 (en) | 2006-02-16 |
| WO2006015874A8 (en) | 2006-04-06 |
| CA2575475A1 (en) | 2006-02-16 |
| WO2006015874B1 (en) | 2006-11-23 |
| US20070178443A1 (en) | 2007-08-02 |
| JP2008509411A (ja) | 2008-03-27 |
| EP1626280B1 (de) | 2007-02-14 |
| JP4516124B2 (ja) | 2010-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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