ATE354582T1 - Klonierung und identifizierung des motilin- rezeptors - Google Patents

Klonierung und identifizierung des motilin- rezeptors

Info

Publication number
ATE354582T1
ATE354582T1 AT99928453T AT99928453T ATE354582T1 AT E354582 T1 ATE354582 T1 AT E354582T1 AT 99928453 T AT99928453 T AT 99928453T AT 99928453 T AT99928453 T AT 99928453T AT E354582 T1 ATE354582 T1 AT E354582T1
Authority
AT
Austria
Prior art keywords
motilin receptor
identification
cloning
receptor
motilin
Prior art date
Application number
AT99928453T
Other languages
English (en)
Inventor
Scott D Feighner
Arthur A Patchett
Carina Tan
Karen Mckee
Douglas Macneil
Andrew D Howard
Sheng-Shung Pong
Roy G Smith
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE354582T1 publication Critical patent/ATE354582T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99928453T 1998-06-12 1999-06-08 Klonierung und identifizierung des motilin- rezeptors ATE354582T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8909898P 1998-06-12 1998-06-12

Publications (1)

Publication Number Publication Date
ATE354582T1 true ATE354582T1 (de) 2007-03-15

Family

ID=22215674

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99928453T ATE354582T1 (de) 1998-06-12 1999-06-08 Klonierung und identifizierung des motilin- rezeptors

Country Status (6)

Country Link
EP (1) EP1086117B1 (de)
JP (1) JP2002517507A (de)
AT (1) ATE354582T1 (de)
CA (1) CA2330251A1 (de)
DE (1) DE69935219D1 (de)
WO (1) WO1999064436A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030229216A1 (en) 1998-10-13 2003-12-11 Ruoping Chen Constitutively activated human G protein coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
EP1228096A4 (de) * 1999-10-29 2003-07-23 Merck & Co Inc Hund- und kaninchen-orthologedes motilinrezeptors
WO2001064836A2 (en) * 2000-03-01 2001-09-07 Smithkline Beecham Corporation Cloning of a gpr38 variant
US20050009204A1 (en) * 2003-07-11 2005-01-13 Ye Fang Multiplexed binding assays for receptor arrays
CN1708309A (zh) * 2002-10-25 2005-12-14 中外制药株式会社 排便功能障碍的治疗和/或预防剂
CA2528375C (en) 2003-06-18 2013-11-19 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
MY150098A (en) * 2005-07-26 2013-11-29 Glaxo Group Ltd Benzylpiperazine derivates and their medical use
EP2431380A3 (de) 2006-09-11 2013-07-03 Tranzyme Pharma, Inc. Makrozyklischer Antagonist des Motilinrezeptors zur Behandlung von Magen-Darm-Motilitätsstörungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B

Also Published As

Publication number Publication date
WO1999064436A1 (en) 1999-12-16
JP2002517507A (ja) 2002-06-18
EP1086117B1 (de) 2007-02-21
DE69935219D1 (de) 2007-04-05
CA2330251A1 (en) 1999-12-16
EP1086117A1 (de) 2001-03-28
EP1086117A4 (de) 2005-05-04

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Legal Events

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