ATE357265T1 - Ladung und abgabe von wasser unlöslicher arzneimittel - Google Patents

Ladung und abgabe von wasser unlöslicher arzneimittel

Info

Publication number
ATE357265T1
ATE357265T1 AT99954837T AT99954837T ATE357265T1 AT E357265 T1 ATE357265 T1 AT E357265T1 AT 99954837 T AT99954837 T AT 99954837T AT 99954837 T AT99954837 T AT 99954837T AT E357265 T1 ATE357265 T1 AT E357265T1
Authority
AT
Austria
Prior art keywords
water
dispensing
loading
medicinal products
medical device
Prior art date
Application number
AT99954837T
Other languages
English (en)
Inventor
James J Barry
Maria Palasis
Original Assignee
Boston Scient Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22626067&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE357265(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boston Scient Ltd filed Critical Boston Scient Ltd
Application granted granted Critical
Publication of ATE357265T1 publication Critical patent/ATE357265T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1027—Making of balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00—Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02—Dilators made of swellable material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • A61L2300/222—Steroids, e.g. corticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1075—Balloon catheters with special features or adapted for special applications having a balloon composed of several layers, e.g. by coating or embedding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1081—Balloon catheters with special features or adapted for special applications having sheaths or the like for covering the balloon but not forming a permanent part of the balloon, e.g. retractable, dissolvable or tearable sheaths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1088—Balloon catheters with special features or adapted for special applications having special surface characteristics depending on material properties or added substances, e.g. for reducing friction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT99954837T 1998-10-14 1999-10-14 Ladung und abgabe von wasser unlöslicher arzneimittel ATE357265T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/172,026 US6306166B1 (en) 1997-08-13 1998-10-14 Loading and release of water-insoluble drugs

Publications (1)

Publication Number Publication Date
ATE357265T1 true ATE357265T1 (de) 2007-04-15

Family

ID=22626067

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99954837T ATE357265T1 (de) 1998-10-14 1999-10-14 Ladung und abgabe von wasser unlöslicher arzneimittel

Country Status (6)

Country Link
US (7) US6306166B1 (de)
EP (2) EP1121162B1 (de)
AT (1) ATE357265T1 (de)
AU (1) AU1108800A (de)
DE (1) DE69935605T2 (de)
WO (1) WO2000021584A1 (de)

Families Citing this family (291)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7846202B2 (en) 1995-06-07 2010-12-07 Cook Incorporated Coated implantable medical device
US7550005B2 (en) 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US7896914B2 (en) 1995-06-07 2011-03-01 Cook Incorporated Coated implantable medical device
US7867275B2 (en) 1995-06-07 2011-01-11 Cook Incorporated Coated implantable medical device method
US7611533B2 (en) 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US20060030826A1 (en) * 1996-06-04 2006-02-09 Vance Products Incorporated,d/b/a Cook Urological Incorporated Implantable medical device with anti-neoplastic drug
US20060052757A1 (en) * 1996-06-04 2006-03-09 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with analgesic or anesthetic
US20060025726A1 (en) * 1996-06-04 2006-02-02 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with pharmacologically active layer
US20030093143A1 (en) * 1999-03-01 2003-05-15 Yiju Zhao Medical device having surface depressions containing nitric oxide releasing compound
US6273913B1 (en) 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6433154B1 (en) * 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US7399480B2 (en) 1997-09-26 2008-07-15 Abbott Laboratories Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
US6890546B2 (en) 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US7445792B2 (en) 2003-03-10 2008-11-04 Abbott Laboratories Medical device having a hydration inhibitor
US8257726B2 (en) * 1997-09-26 2012-09-04 Abbott Laboratories Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
US8057816B2 (en) * 1997-09-26 2011-11-15 Abbott Laboratories Compositions and methods of administering paclitaxel with other drugs using medical devices
US20070093889A1 (en) * 1999-01-27 2007-04-26 Wu Benjamin M Non-Fragmenting Low Friction Bioactive Absorbable Coils for Brain Aneurysm Therapy
US6241762B1 (en) 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US7208011B2 (en) 2001-08-20 2007-04-24 Conor Medsystems, Inc. Implantable medical device with drug filled holes
US20040254635A1 (en) 1998-03-30 2004-12-16 Shanley John F. Expandable medical device for delivery of beneficial agent
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US8029561B1 (en) 2000-05-12 2011-10-04 Cordis Corporation Drug combination useful for prevention of restenosis
US8177743B2 (en) 1998-05-18 2012-05-15 Boston Scientific Scimed, Inc. Localized delivery of drug agents
CA2340652C (en) * 1998-08-20 2013-09-24 Cook Incorporated Coated implantable medical device comprising paclitaxel
US20050171594A1 (en) * 1998-12-31 2005-08-04 Angiotech International Ag Stent grafts with bioactive coatings
US20020065546A1 (en) * 1998-12-31 2002-05-30 Machan Lindsay S. Stent grafts with bioactive coatings
US6709465B2 (en) 1999-03-18 2004-03-23 Fossa Medical, Inc. Radially expanding ureteral device
US7214229B2 (en) 1999-03-18 2007-05-08 Fossa Medical, Inc. Radially expanding stents
US6258121B1 (en) * 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
US7300662B2 (en) 2000-05-12 2007-11-27 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
US6764720B2 (en) * 2000-05-16 2004-07-20 Regents Of The University Of Minnesota High mass throughput particle generation using multiple nozzle spraying
US6974473B2 (en) * 2000-06-30 2005-12-13 Vascular Architects, Inc. Function-enhanced thrombolytic AV fistula and method
ATE404140T1 (de) 2000-08-30 2008-08-15 Univ Johns Hopkins Vorrichtung zur intraokularen wirkstoffverabreichung
US6620196B1 (en) * 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US7261735B2 (en) 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
AU9486901A (en) 2000-09-29 2002-04-08 Cordis Corp Coated medical devices
US20020111590A1 (en) 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
PT1328213E (pt) 2000-10-16 2005-10-31 Conor Medsystems Inc Dispositivo medico expansivel para a administracao de um agente benefico
US6607553B1 (en) 2000-11-17 2003-08-19 B. Braun Medical, Inc. Method for deploying a thermo-mechanically expandable stent
EP1339502B1 (de) * 2000-12-04 2004-09-29 Grüssner, Uwe Emil Vorrichtung zur Beschichtung eines Gegenstands mit einem Wirkstoff und Verfahren zur Herstellung eines partiellen oder vollständigen Wirkstoffüberzuges auf und im Implantaten und Onplantaten sowie Verwendung dieses Verfahrens und durch dieses Verfahren hergestelltes Erzeugnis
US20040220660A1 (en) * 2001-02-05 2004-11-04 Shanley John F. Bioresorbable stent with beneficial agent reservoirs
US20040073294A1 (en) 2002-09-20 2004-04-15 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
US8182527B2 (en) 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
US7247338B2 (en) * 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
US6656216B1 (en) 2001-06-29 2003-12-02 Advanced Cardiovascular Systems, Inc. Composite stent with regioselective material
US7842083B2 (en) 2001-08-20 2010-11-30 Innovational Holdings, Llc. Expandable medical device with improved spatial distribution
US7056338B2 (en) 2003-03-28 2006-06-06 Conor Medsystems, Inc. Therapeutic agent delivery device with controlled therapeutic agent release rates
WO2003020331A1 (de) * 2001-09-03 2003-03-13 Oxigene, Inc. Implantate mit combretastatin a-4
US8303651B1 (en) 2001-09-07 2012-11-06 Advanced Cardiovascular Systems, Inc. Polymeric coating for reducing the rate of release of a therapeutic substance from a stent
GB0121980D0 (en) * 2001-09-11 2001-10-31 Cathnet Science Holding As Expandable stent
US20050025808A1 (en) * 2001-09-24 2005-02-03 Herrmann Robert A. Medical devices and methods for inhibiting smooth muscle cell proliferation
AU2007202976B2 (en) * 2001-09-24 2008-12-04 Boston Scientific Limited Optimized dosing for drug coated stents
WO2003035135A1 (en) * 2001-09-24 2003-05-01 Boston Scientific Limited Optimized dosing for drug coated stents
US7195640B2 (en) 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US7108701B2 (en) 2001-09-28 2006-09-19 Ethicon, Inc. Drug releasing anastomosis devices and methods for treating anastomotic sites
SI1438065T1 (sl) * 2001-10-01 2013-03-29 Martizyme Pharma Corporation Uporaba kolagenaze za olajšanje prehoda vodilne žice skozi kronične arterijske okluzije
US20030065382A1 (en) * 2001-10-02 2003-04-03 Fischell Robert E. Means and method for the treatment of coronary artery obstructions
US20030077310A1 (en) 2001-10-22 2003-04-24 Chandrashekhar Pathak Stent coatings containing HMG-CoA reductase inhibitors
US20040111108A1 (en) 2001-11-09 2004-06-10 Farnan Robert C. Balloon catheter with non-deployable stent
EP1441669B1 (de) 2001-11-09 2009-03-25 AngioScore, Inc. Ballonkatheter mit nicht ablegbarem stent
WO2003041757A2 (en) * 2001-11-14 2003-05-22 Alza Corporation Catheter injectable depot compositions and uses thereof
US20070196415A1 (en) * 2002-11-14 2007-08-23 Guohua Chen Depot compositions with multiple drug release rate controls and uses thereof
US8080048B2 (en) 2001-12-03 2011-12-20 Xtent, Inc. Stent delivery for bifurcated vessels
US20030135266A1 (en) * 2001-12-03 2003-07-17 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7147656B2 (en) * 2001-12-03 2006-12-12 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US20040186551A1 (en) * 2003-01-17 2004-09-23 Xtent, Inc. Multiple independent nested stent structures and methods for their preparation and deployment
US7309350B2 (en) * 2001-12-03 2007-12-18 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US7351255B2 (en) * 2001-12-03 2008-04-01 Xtent, Inc. Stent delivery apparatus and method
US7892273B2 (en) * 2001-12-03 2011-02-22 Xtent, Inc. Custom length stent apparatus
US7294146B2 (en) 2001-12-03 2007-11-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US7137993B2 (en) 2001-12-03 2006-11-21 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7182779B2 (en) * 2001-12-03 2007-02-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US7270668B2 (en) * 2001-12-03 2007-09-18 Xtent, Inc. Apparatus and methods for delivering coiled prostheses
AU2002360712A1 (en) * 2001-12-21 2003-07-30 The Trustees Of Columbia University In The City Of New York C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis
US8142412B2 (en) * 2002-01-03 2012-03-27 Oxira Medical Inc. Method and apparatus for delivering oxygen and/or other gases to tissue
US7008979B2 (en) 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
US7709048B2 (en) * 2002-05-02 2010-05-04 Labcoat, Ltd. Method and apparatus for coating a medical device
US6645547B1 (en) * 2002-05-02 2003-11-11 Labcoat Ltd. Stent coating device
US7048962B2 (en) * 2002-05-02 2006-05-23 Labcoat, Ltd. Stent coating device
US20030208166A1 (en) * 2002-05-06 2003-11-06 Schwartz Anthony H. Implantable device with free-flowing exit and uses thereof
DE50310322D1 (de) * 2002-05-09 2008-09-25 Hemoteq Ag Hemokompatibel beschichtete medizinprodukte, deren herstellung und verwendung
DE10221055B4 (de) * 2002-05-10 2007-10-25 Hemoteq Ag Verbindungen zur hämokompatiblen Beschichtung von Oberflächen, Verfahren zu deren Herstellung und deren Verwendung
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
CA2484761C (en) * 2002-05-24 2010-11-09 Angiotech International Ag Compositions and methods for coating medical implants
US7105175B2 (en) * 2002-06-19 2006-09-12 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US8211455B2 (en) * 2002-06-19 2012-07-03 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US7939094B2 (en) * 2002-06-19 2011-05-10 Boston Scientific Scimed, Inc. Multiphase polymeric drug release region
US6994867B1 (en) 2002-06-21 2006-02-07 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing L-arginine
US7011842B1 (en) 2002-06-21 2006-03-14 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of making the same
US7070798B1 (en) 2002-06-21 2006-07-04 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine
US7056523B1 (en) 2002-06-21 2006-06-06 Advanced Cardiovascular Systems, Inc. Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine
US7033602B1 (en) 2002-06-21 2006-04-25 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of coating implantable medical devices
US8506617B1 (en) 2002-06-21 2013-08-13 Advanced Cardiovascular Systems, Inc. Micronized peptide coated stent
US7794743B2 (en) 2002-06-21 2010-09-14 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of making the same
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US20040001889A1 (en) * 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
CA2484383C (en) 2002-07-12 2016-05-31 Cook Incorporated Medical device coated with a bioactive agent
US7622146B2 (en) * 2002-07-18 2009-11-24 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices and methods for fabrication thereof
WO2004011054A2 (en) * 2002-07-31 2004-02-05 Alza Corporation Injectable multimodal polymer depot compositions and uses thereof
KR20050038008A (ko) * 2002-07-31 2005-04-25 알자 코포레이션 주사용 저장형 조성물 및 이의 용도
US20040024448A1 (en) 2002-08-05 2004-02-05 Chang James W. Thermoplastic fluoropolymer-coated medical devices
US7438925B2 (en) * 2002-08-26 2008-10-21 Biovention Holdings Ltd. Drug eluting coatings for medical implants
US7758636B2 (en) 2002-09-20 2010-07-20 Innovational Holdings Llc Expandable medical device with openings for delivery of multiple beneficial agents
DE10244847A1 (de) * 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
US7094256B1 (en) 2002-12-16 2006-08-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical device containing polycationic peptides
CA2511484A1 (en) * 2002-12-30 2004-07-22 Angiotech International Ag Silk-containing stent graft
US8080026B2 (en) 2003-01-21 2011-12-20 Angioscore, Inc. Apparatus and methods for treating hardened vascular lesions
US8313759B2 (en) * 2003-03-06 2012-11-20 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing miscible polymer blends for controlled delivery of a therapeutic agent
AU2004226327A1 (en) 2003-03-28 2004-10-14 Innovational Holdings, Llc Implantable medical device with beneficial agent concentration gradient
CA2525393A1 (en) * 2003-05-28 2004-12-23 Conor Medsystems, Inc. Methods of delivering anti-restenotic agents from a stent
US7241308B2 (en) * 2003-06-09 2007-07-10 Xtent, Inc. Stent deployment systems and methods
US7318945B2 (en) * 2003-07-09 2008-01-15 Medtronic Vascular, Inc. Laminated drug-polymer coated stent having dipped layers
US7335185B2 (en) * 2003-07-18 2008-02-26 Boston Scientific Scimed, Inc. Protective coatings for medical devices
US6840569B1 (en) * 2003-07-22 2005-01-11 Arthur Donald Leigh Caravan
US7744645B2 (en) * 2003-09-29 2010-06-29 Medtronic Vascular, Inc. Laminated drug-polymer coated stent with dipped and cured layers
US7553324B2 (en) * 2003-10-14 2009-06-30 Xtent, Inc. Fixed stent delivery devices and methods
US20050080475A1 (en) * 2003-10-14 2005-04-14 Xtent, Inc. A Delaware Corporation Stent delivery devices and methods
US7192440B2 (en) * 2003-10-15 2007-03-20 Xtent, Inc. Implantable stent delivery devices and methods
US7553326B2 (en) 2003-11-24 2009-06-30 Sweet Richard M Method and apparatus for preventing dialysis graft intimal hyperplasia
US7403966B2 (en) * 2003-12-08 2008-07-22 Freescale Semiconductor, Inc. Hardware for performing an arithmetic function
US20070156225A1 (en) * 2003-12-23 2007-07-05 Xtent, Inc. Automated control mechanisms and methods for custom length stent apparatus
US7326236B2 (en) 2003-12-23 2008-02-05 Xtent, Inc. Devices and methods for controlling and indicating the length of an interventional element
US8309112B2 (en) * 2003-12-24 2012-11-13 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same
DE102004009318B4 (de) * 2004-02-26 2006-05-04 Siemens Ag Vorrichtung zur wiederholten semi-invasiven Abrasion von Veränderungen an den Wänden von Hohlorganen
AU2005222719B2 (en) * 2004-03-19 2011-03-24 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
US20070027523A1 (en) * 2004-03-19 2007-02-01 Toner John L Method of treating vascular disease at a bifurcated vessel using coated balloon
US8431145B2 (en) 2004-03-19 2013-04-30 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
US20100030183A1 (en) * 2004-03-19 2010-02-04 Toner John L Method of treating vascular disease at a bifurcated vessel using a coated balloon
US7323006B2 (en) * 2004-03-30 2008-01-29 Xtent, Inc. Rapid exchange interventional devices and methods
US20050226991A1 (en) * 2004-04-07 2005-10-13 Hossainy Syed F Methods for modifying balloon of a catheter assembly
US20050228477A1 (en) * 2004-04-09 2005-10-13 Xtent, Inc. Topographic coatings and coating methods for medical devices
WO2005105171A1 (en) * 2004-04-29 2005-11-10 Cube Medical A/S A balloon for use in angioplasty with an outer layer of nanofibers
US20050255230A1 (en) * 2004-05-17 2005-11-17 Clerc Claude O Method of manufacturing a covered stent
WO2005118016A1 (en) * 2004-05-27 2005-12-15 Medtronic, Inc. Medical device comprising a biologically active agent
US20050288766A1 (en) * 2004-06-28 2005-12-29 Xtent, Inc. Devices and methods for controlling expandable prostheses during deployment
US8317859B2 (en) 2004-06-28 2012-11-27 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
USD516723S1 (en) 2004-07-06 2006-03-07 Conor Medsystems, Inc. Stent wall structure
WO2006017275A1 (en) 2004-07-13 2006-02-16 The University Of Tennessee Research Foundation Adhesive composition for carrying therapeutic agents as delivery vehicle on coatings applied to vascular grafts
EP1791496B1 (de) 2004-08-31 2019-07-31 C.R. Bard, Inc. Selbstschliessendes ptfe-implantat mit knickbeständigkeit
US20060069424A1 (en) * 2004-09-27 2006-03-30 Xtent, Inc. Self-constrained segmented stents and methods for their deployment
US9011831B2 (en) * 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
US20060093643A1 (en) * 2004-11-04 2006-05-04 Stenzel Eric B Medical device for delivering therapeutic agents over different time periods
US20060142234A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
US20060206139A1 (en) * 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US7402168B2 (en) * 2005-04-11 2008-07-22 Xtent, Inc. Custom-length stent delivery system with independently operable expansion elements
US10076641B2 (en) 2005-05-11 2018-09-18 The Spectranetics Corporation Methods and systems for delivering substances into luminal walls
JP2008543376A (ja) * 2005-06-08 2008-12-04 シー・アール・バード・インコーポレーテッド 無機生体適合性カルシウム塩を有するグラフト及びステント
WO2007001472A2 (en) 2005-06-17 2007-01-04 C. R. Bard, Inc. Vascular graft with kink resistance after clamping
US9101949B2 (en) 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
US7896539B2 (en) 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
JP5118042B2 (ja) * 2005-09-06 2013-01-16 シー・アール・バード・インコーポレーテッド 薬物結晶を含有する移植用インプラント
US8900620B2 (en) 2005-10-13 2014-12-02 DePuy Synthes Products, LLC Drug-impregnated encasement
US8636794B2 (en) 2005-11-09 2014-01-28 C. R. Bard, Inc. Grafts and stent grafts having a radiopaque marker
CN1962155A (zh) * 2005-11-10 2007-05-16 鸿富锦精密工业（深圳）有限公司 一种二氧化碳激光焊接装置
US20080286325A1 (en) * 2006-01-05 2008-11-20 Med Institute, Inc. Cyclodextrin elution media for medical device coatings comprising a taxane therapeutic agent
US7919108B2 (en) * 2006-03-10 2011-04-05 Cook Incorporated Taxane coatings for implantable medical devices
US8092819B2 (en) * 2006-01-27 2012-01-10 Cook Medical Technologies LLC. Implantable medical device coated with a bioactive agent
US20070179587A1 (en) * 2006-01-30 2007-08-02 Xtent, Inc. Apparatus and methods for deployment of custom-length prostheses
US7951428B2 (en) 2006-01-31 2011-05-31 Regents Of The University Of Minnesota Electrospray coating of objects
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
EP2529761B1 (de) * 2006-01-31 2017-06-14 Nanocopoeia, Inc. Oberflächenbeschichtung mit nanoteilchen
US7875284B2 (en) * 2006-03-10 2011-01-25 Cook Incorporated Methods of manufacturing and modifying taxane coatings for implantable medical devices
AU2007227000A1 (en) 2006-03-20 2007-09-27 Xtent, Inc. Apparatus and methods for deployment of linked prosthetic segments
US20070281117A1 (en) * 2006-06-02 2007-12-06 Xtent, Inc. Use of plasma in formation of biodegradable stent coating
US8703167B2 (en) * 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
CA2656635C (en) * 2006-07-03 2013-05-28 Hemoteq Ag Stent with polymeric coating comprising rapamycin as an active agent
US20080051702A1 (en) * 2006-08-24 2008-02-28 Herrmann Robert A Therapeutic agent delivery for the treatment of asthma via implantable and insertable medical devices
US8394488B2 (en) * 2006-10-06 2013-03-12 Cordis Corporation Bioabsorbable device having composite structure for accelerating degradation
EP2079575B1 (de) 2006-10-12 2021-06-02 C.R. Bard, Inc. Herstellungsverfahren für gefässtransplantate mit mehreren kanälen
US20080175887A1 (en) 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US9040816B2 (en) * 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
US20080152784A1 (en) * 2006-12-22 2008-06-26 Boston Scientific Scimed, Inc. Methods of manufacturing coatings and coated medical devices
NZ578341A (en) 2007-01-21 2011-06-30 Hemoteq Ag Method for producing a coated catheter balloon
DE102007003184A1 (de) * 2007-01-22 2008-07-24 Orlowski, Michael, Dr. Verfahren zur Beladung von strukturierten Oberflächen
US20080199510A1 (en) 2007-02-20 2008-08-21 Xtent, Inc. Thermo-mechanically controlled implants and methods of use
US8486132B2 (en) 2007-03-22 2013-07-16 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
GR20070100224A (el) * 2007-04-13 2008-11-14 Κωνστατινος Σπαργιας Μπαλονι βαλβιδοπλαστικης για την στενωση αορτικησβαλβιδας που φερει επιστρωση εκλυομενης φαρμακευτικης ουσιας η οποια επιδρα προληπτικα κατα της επαναστενωσης.
GR20070100291A (el) * 2007-05-14 2008-12-19 Κωνστατινος Σπαργιας Μπαλονια βαλβιδοπλαστικης για την στενωση αορτικης βαλβιδας που φερουν επιστρωση εκλυομενης φαρμακευτικης ουσιας η οποια επιδρα προληπτικα κατα της επαναστενωσης
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
DE102007036685A1 (de) 2007-08-03 2009-02-05 Innora Gmbh Verbesserte arzneimittelbeschichtete Medizinprodukte deren Herstellung und Verwendung
DE102007040868A1 (de) * 2007-08-29 2009-04-16 Innora Gmbh Ballonkatheter mit Schutz vor Auffaltung
US20090076584A1 (en) * 2007-09-19 2009-03-19 Xtent, Inc. Apparatus and methods for deployment of multiple custom-length prostheses
CN103549986B (zh) 2008-02-22 2015-12-09 泰科保健集团有限合伙公司 可去除的结合的血栓装置团块
US20110150961A1 (en) * 2008-02-22 2011-06-23 Angiotech International Ag Anti-infective catheters
US9101503B2 (en) * 2008-03-06 2015-08-11 J.W. Medical Systems Ltd. Apparatus having variable strut length and methods of use
EP2262547B1 (de) * 2008-03-06 2013-01-09 Boston Scientific Scimed, Inc. Ballonkathetervorrichtungen mit in lösungsmittel quellbarem polymer
WO2009124570A1 (de) * 2008-04-09 2009-10-15 Ruebben Alexander Verfahren zur erzeugung einer bioaktiven oberfläche auf einer endoprothese oder auf dem ballon eines ballonkatheters
WO2009135125A2 (en) 2008-05-01 2009-11-05 Bayer Schering Pharma Ag Catheter balloon drug adherence techniques and methods
DE102008034826A1 (de) * 2008-07-22 2010-01-28 Alexander Rübben Verfahren zur Erzeugung einer bioaktiven Oberfläche auf dem Ballon eines Ballonkatheters
WO2010024898A2 (en) 2008-08-29 2010-03-04 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US9198968B2 (en) * 2008-09-15 2015-12-01 The Spectranetics Corporation Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8128951B2 (en) 2008-09-15 2012-03-06 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8114429B2 (en) 2008-09-15 2012-02-14 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8257722B2 (en) 2008-09-15 2012-09-04 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8808347B2 (en) 2008-09-25 2014-08-19 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US12076258B2 (en) 2008-09-25 2024-09-03 Advanced Bifurcation Systems Inc. Selective stent crimping
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US8821562B2 (en) 2008-09-25 2014-09-02 Advanced Bifurcation Systems, Inc. Partially crimped stent
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
US11298252B2 (en) 2008-09-25 2022-04-12 Advanced Bifurcation Systems Inc. Stent alignment during treatment of a bifurcation
US8769796B2 (en) 2008-09-25 2014-07-08 Advanced Bifurcation Systems, Inc. Selective stent crimping
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
AU2009296415B2 (en) 2008-09-25 2015-11-19 Advanced Bifurcation Systems Inc. Partially crimped stent
US12324756B2 (en) 2008-09-25 2025-06-10 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation
DE202009004536U1 (de) * 2009-03-25 2010-08-12 Marx, Karl-Heinz Set zur Schaffung eines künstlichen Mageneinganges
US20100285085A1 (en) * 2009-05-07 2010-11-11 Abbott Cardiovascular Systems Inc. Balloon coating with drug transfer control via coating thickness
EP2944332B1 (de) 2009-07-10 2016-08-17 Boston Scientific Scimed, Inc. Verwendung von nanokristallen für einen wirkstofffreisetzungsballon
EP2453938B1 (de) 2009-07-17 2015-08-19 Boston Scientific Scimed, Inc. Nukleierung von wirkstofffreisetzungsballons für verbesserte kristallgrösse und -dichte
US8951595B2 (en) 2009-12-11 2015-02-10 Abbott Cardiovascular Systems Inc. Coatings with tunable molecular architecture for drug-coated balloon
US8480620B2 (en) * 2009-12-11 2013-07-09 Abbott Cardiovascular Systems Inc. Coatings with tunable solubility profile for drug-coated balloon
JP2013514278A (ja) 2009-12-18 2013-04-25 インターフェース バイオロジクス，インコーポレーテッド 自己集合コーティングからの薬物の局所送達
EP2338534A2 (de) * 2009-12-21 2011-06-29 Biotronik VI Patent AG Medizinisches Implantat, Beschichtungsverfahren sowie Implantationsverfahren
US20110160645A1 (en) * 2009-12-31 2011-06-30 Boston Scientific Scimed, Inc. Cryo Activated Drug Delivery and Cutting Balloons
WO2011119536A1 (en) 2010-03-22 2011-09-29 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
CA2794064A1 (en) 2010-03-24 2011-09-29 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
EP2549952A4 (de) 2010-03-24 2017-01-04 Advanced Bifurcation Systems, Inc. System und verfahren zur behandlung einer bifurkation
EP2380604A1 (de) 2010-04-19 2011-10-26 InnoRa Gmbh Verbesserte Beschichtungsformulierung zum Einritzen oder Schneiden von Ballonkathetern
EP2383000A1 (de) 2010-04-19 2011-11-02 InnoRa Gmbh Limusbeschichtete medizinische Vorrichtungen
EP2380605A1 (de) 2010-04-19 2011-10-26 InnoRa Gmbh Verbesserte Formulierungen für wirkstoffbeschichtete medizinische Vorrichtungen
US8840542B2 (en) 2010-06-10 2014-09-23 Myriad Medical, Llc Intracavity balloon catheter
EP2611476B1 (de) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Beschichtungsverfahren für wirkstofffreisetzungsballons mit wärmeinduziertem rewrap-gedächtnis
US8632559B2 (en) 2010-09-21 2014-01-21 Angioscore, Inc. Method and system for treating valve stenosis
WO2012039884A1 (en) 2010-09-23 2012-03-29 Boston Scientific Scimed, Inc. Drug coated balloon with transferable coating
ES2673026T3 (es) * 2010-12-04 2018-06-19 Aachen Scientific International Pte. Ltd. Revestimiento y procedimiento de revestimiento para el balón de un catéter de balón, así como catéter de balón con balón revestido
EP2654874B1 (de) 2010-12-21 2018-04-11 Invatec Technology Center GMBH Strukturierter wirkstoff-freisetzender ballon zur behandlung von stenosen und verfahren zur herstellung des ballons
EP2672932B1 (de) 2011-02-08 2018-09-19 Advanced Bifurcation Systems, Inc. System zur behandlung einer gabelung mit einem vollständig gecrimpten stent
EP2672925B1 (de) 2011-02-08 2017-05-03 Advanced Bifurcation Systems, Inc. Multi-stent- und multi-ballon-vorrichtung zur behandlung von abzweigungen
US9415193B2 (en) 2011-03-04 2016-08-16 W. L. Gore & Associates, Inc. Eluting medical devices
US20130030406A1 (en) 2011-07-26 2013-01-31 Medtronic Vascular, Inc. Textured Dilatation Balloon and Methods
WO2013022458A1 (en) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
JP2014530067A (ja) 2011-10-14 2014-11-17 イノラ ゲーエムベーハ 薬剤被覆医療装置用の改良された製剤
WO2013091722A1 (en) 2011-12-23 2013-06-27 Innora Gmbh Drug-coated medical devices
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
AU2013238160B2 (en) 2012-03-27 2016-03-31 Terumo Kabushiki Kaisha Coating composition and medical device
CN104168927B (zh) * 2012-03-27 2016-10-05 泰尔茂株式会社 涂布组合物及医疗器械
US9220584B2 (en) 2012-03-30 2015-12-29 Abbott Cardiovascular Systems Inc. Treatment of diabetic patients with a stent and locally administered adjunctive therapy
MX351261B (es) 2012-06-01 2017-10-06 Surmodics Inc Aparato y método para recubrir catéteres con globo.
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
US10173038B2 (en) 2012-09-05 2019-01-08 W. L. Gore & Associates, Inc. Retractable sheath devices, systems, and methods
US10850076B2 (en) 2012-10-26 2020-12-01 Urotronic, Inc. Balloon catheters for body lumens
WO2016172343A1 (en) 2015-04-24 2016-10-27 Urotronic, Inc. Drug coated balloon catheters for nonvascular strictures
US11504450B2 (en) 2012-10-26 2022-11-22 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US10898700B2 (en) 2012-10-26 2021-01-26 Urotronic, Inc. Balloon catheters for body lumens
JP2015536709A (ja) 2012-10-26 2015-12-24 ウロトロニック・インコーポレイテッドＵｒｏｔｒｏｎｉｃ， Ｉｎｃ． 非血管狭窄のための薬物被覆バルーンカテーテル
US11938287B2 (en) 2012-10-26 2024-03-26 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US10806830B2 (en) 2012-10-26 2020-10-20 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US10881839B2 (en) 2012-10-26 2021-01-05 Urotronic, Inc. Drug-coated balloon catheters for body lumens
WO2014070792A1 (en) 2012-10-29 2014-05-08 Ariste Medical, Inc. Polymer coating compositions and coated products
AU2014281010B2 (en) 2013-06-21 2018-05-10 DePuy Synthes Products, Inc. Films and methods of manufacture
US10117668B2 (en) 2013-10-08 2018-11-06 The Spectranetics Corporation Balloon catheter with non-deployable stent having improved stability
US20160303242A1 (en) 2013-12-09 2016-10-20 Durect Corporation Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same
US10525171B2 (en) 2014-01-24 2020-01-07 The Spectranetics Corporation Coatings for medical devices
GB2537770B (en) 2014-04-22 2017-09-13 Ariste Medical Llc Methods and processes for application of drug delivery polymeric coatings
JP6008213B2 (ja) * 2014-08-06 2016-10-19 リューベン，アレクサンダー 体内プロテーゼ上又はバルーンカテーテルのバルーン上の生体活性表面の製造方法
CN107427612A (zh) * 2014-10-07 2017-12-01 耶路撒冷希伯来大学伊森姆研究发展有限公司 按需可降解的医疗装置
EP3042687B1 (de) 2015-01-08 2020-10-14 Myriad Medical LLC Intrakavitärer ballonkatheter
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
US11904072B2 (en) 2015-04-24 2024-02-20 Urotronic, Inc. Drug coated balloon catheters for nonvascular strictures
US11969567B2 (en) * 2015-11-18 2024-04-30 Spectranetics Llc Balloon angioplasty catheter coating to encourage vessel repair and further reduce restenosis
CN107865982B (zh) * 2016-09-28 2020-09-25 先健科技(深圳)有限公司 药物涂层球囊
JP2020536955A (ja) 2017-10-06 2020-12-17 ファウンドリー セラピューティクス， インコーポレイテッド 治療剤の制御放出のための埋込み可能なデポー
EP3737433A1 (de) * 2018-01-08 2020-11-18 Foundry Therapeutics, Inc. Vorrichtungen, systeme und verfahren zur behandlung von intraluminalem krebs durch kontrollierte abgabe von therapeutika
WO2019221853A1 (en) 2018-05-12 2019-11-21 Foundry Therapeutics, Inc. Implantable depots for the controlled release of therapeutic agents
JP2021531061A (ja) 2018-05-22 2021-11-18 インターフェース バイオロジクス，インコーポレーテッド 薬物を脈管壁に送達するための組成物及び方法
EP3843710A1 (de) 2018-08-28 2021-07-07 Foundry Therapeutics, Inc. Polymerimplantate
WO2020112816A1 (en) 2018-11-29 2020-06-04 Surmodics, Inc. Apparatus and methods for coating medical devices
EP4223352A3 (de) 2019-02-22 2023-11-01 Urotronic, Inc. Medikamentenbeschichtete ballonkatheter für körperlumen
US11819590B2 (en) 2019-05-13 2023-11-21 Surmodics, Inc. Apparatus and methods for coating medical devices
CA3167217A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CN119236187A (zh) 2020-02-21 2025-01-03 吉益医疗公司 聚合物包封的药物颗粒
US12496612B2 (en) 2021-01-08 2025-12-16 Surmodics, Inc. Coating application system and methods for coating rotatable medical devices
CN116940358A (zh) 2021-01-12 2023-10-24 度勒科特公司 持续释放药物递送系统和有关的方法
US20240269353A1 (en) * 2021-05-21 2024-08-15 Know Bio, Llc Nitric oxide-releasing devices

Family Cites Families (211)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US304121A (en) * 1884-08-26 Helm munch
US556922A (en) * 1896-03-24 gilpatrick
CS173836B1 (de) 1974-03-19 1977-03-31
US4186745A (en) * 1976-07-30 1980-02-05 Kauzlarich James J Porous catheters
US4481323A (en) 1980-05-07 1984-11-06 Medical Research Associates, Ltd. #2 Hydrocarbon block copolymer with dispersed polysiloxane
US4515593A (en) 1981-12-31 1985-05-07 C. R. Bard, Inc. Medical tubing having exterior hydrophilic coating for microbiocide absorption therein and method for using same
CA1191064A (en) 1981-12-31 1985-07-30 Bard (C. R.), Inc. Catheter with selectively rigidified portion
US4769013A (en) 1982-09-13 1988-09-06 Hydromer, Inc. Bio-effecting medical material and device
NZ205680A (en) 1982-10-01 1986-05-09 Ethicon Inc Glycolide/epsilon-caprolactone copolymers and sterile surgical articles made therefrom
US4603152A (en) 1982-11-05 1986-07-29 Baxter Travenol Laboratories, Inc. Antimicrobial compositions
US4644936A (en) * 1982-11-19 1987-02-24 Iabp Percutaneous intra-aortic balloon and method for using same
US4693243A (en) 1983-01-14 1987-09-15 Buras Sharon Y Conduit system for directly administering topical anaesthesia to blocked laryngeal-tracheal areas
US4589873A (en) 1984-05-29 1986-05-20 Becton, Dickinson And Company Method of applying a hydrophilic coating to a polymeric substrate and articles prepared thereby
US4733665C2 (en) * 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4784647A (en) 1986-07-30 1988-11-15 The Kendal Company Catheter meatal pad device
US4800882A (en) * 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US4796629A (en) * 1987-06-03 1989-01-10 Joseph Grayzel Stiffened dilation balloon catheter device
US4886062A (en) * 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
US4950256A (en) 1988-04-07 1990-08-21 Luther Medical Products, Inc. Non-thrombogenic intravascular time release catheter
JP2683750B2 (ja) 1988-06-06 1997-12-03 住友電気工業株式会社 カテーテル用バルーン
DE3821544C2 (de) 1988-06-25 1994-04-28 H Prof Dr Med Just Dilatationskatheter
US6730105B2 (en) * 1988-07-29 2004-05-04 Samuel Shiber Clover leaf shaped tubular medical device
US4950239A (en) * 1988-08-09 1990-08-21 Worldwide Medical Plastics Inc. Angioplasty balloons and balloon catheters
US4906244A (en) * 1988-10-04 1990-03-06 Cordis Corporation Balloons for medical devices and fabrication thereof
US5091205A (en) 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
FR2642474B1 (fr) * 1989-01-27 1992-05-15 Floquet Monopole Axe creux, en particulier pour piston de moteur a combustion interne, et son procede de fabrication
US5087244A (en) 1989-01-31 1992-02-11 C. R. Bard, Inc. Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen
US5041100A (en) 1989-04-28 1991-08-20 Cordis Corporation Catheter and hydrophilic, friction-reducing coating thereon
US4994033A (en) 1989-05-25 1991-02-19 Schneider (Usa) Inc. Intravascular drug delivery dilatation catheter
US5049131A (en) * 1989-05-31 1991-09-17 Ashridge Ag Balloon catheter
US5026607A (en) 1989-06-23 1991-06-25 C. R. Bard, Inc. Medical apparatus having protective, lubricious coating
US5135516A (en) 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5674192A (en) 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
US5545208A (en) 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
WO1991012779A1 (en) 1990-02-28 1991-09-05 Medtronic, Inc. Intralumenal drug eluting prosthesis
AU7998091A (en) 1990-05-17 1991-12-10 Harbor Medical Devices, Inc. Medical device polymer
US5320634A (en) * 1990-07-03 1994-06-14 Interventional Technologies, Inc. Balloon catheter with seated cutting edges
US5196024A (en) * 1990-07-03 1993-03-23 Cedars-Sinai Medical Center Balloon catheter with cutting edge
US5180366A (en) * 1990-10-10 1993-01-19 Woods W T Apparatus and method for angioplasty and for preventing re-stenosis
EP0556316B1 (de) * 1990-11-09 1997-01-22 Boston Scientific Corporation Führungsdraht zum durchqueren von okklusionen in blutgefässen
US5102402A (en) 1991-01-04 1992-04-07 Medtronic, Inc. Releasable coatings on balloon catheters
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5500013A (en) 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
JP3053029B2 (ja) * 1991-10-08 2000-06-19 テルモ株式会社 血管拡張用カテーテルバルーン
US5282823A (en) 1992-03-19 1994-02-01 Medtronic, Inc. Intravascular radially expandable stent
US5599352A (en) 1992-03-19 1997-02-04 Medtronic, Inc. Method of making a drug eluting stent
US5571166A (en) 1992-03-19 1996-11-05 Medtronic, Inc. Method of making an intraluminal stent
DE69311847T2 (de) * 1992-04-06 1997-11-13 Terumo Corp Ballonkatheter
US5629008A (en) 1992-06-02 1997-05-13 C.R. Bard, Inc. Method and device for long-term delivery of drugs
US5383928A (en) 1992-06-10 1995-01-24 Emory University Stent sheath for local drug delivery
US5500180A (en) * 1992-09-30 1996-03-19 C. R. Bard, Inc. Method of making a distensible dilatation balloon using a block copolymer
US5489525A (en) * 1992-10-08 1996-02-06 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies to prostate cells
GB9221220D0 (en) * 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5302634A (en) * 1992-10-15 1994-04-12 Hoppmann Corporation Cured unsaturated polyester-polyurethane hybrid highly filled resin foams
US5634901A (en) * 1992-11-02 1997-06-03 Localmed, Inc. Method of using a catheter sleeve
US5578075B1 (en) 1992-11-04 2000-02-08 Daynke Res Inc Minimally invasive bioactivated endoprosthesis for vessel repair
US5449382A (en) 1992-11-04 1995-09-12 Dayton; Michael P. Minimally invasive bioactivated endoprosthesis for vessel repair
US5419760A (en) 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
JPH08507715A (ja) 1993-03-18 1996-08-20 シーダーズ サイナイ メディカル センター 生体人工部材のための薬剤導入性および放出性重合性コーティング
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
JP3470270B2 (ja) * 1993-06-02 2003-11-25 シメッド ライフ システムズ、インコーポレーテッド バルーンカテーテルにおける潤滑性被膜の選択的配置
US5716981A (en) * 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
CN1502331A (zh) 1993-07-19 2004-06-09 Ѫ�ܼ���ҩ�﹫˾ 抗血管生长组合物及使用方法
US5380299A (en) 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
JP3577082B2 (ja) * 1993-10-01 2004-10-13 ボストン・サイエンティフィック・コーポレーション 熱可塑性エラストマーから成る医療装置用バルーン
JP3494654B2 (ja) * 1994-03-02 2004-02-09 シメッド ライフ システムズ インコーポレイテッド ブロックコポリマーエラストマー・カテーテル・バルーン
DE4421878B4 (de) * 1994-06-23 2007-09-27 Valeo Wischersysteme Gmbh Schwingungsdämpfende Befestigung einer Scheibenwischerantriebseinrichtung
US5626862A (en) * 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
DE4428851C2 (de) * 1994-08-04 2000-05-04 Diagnostikforschung Inst Eisen enthaltende Nanopartikel, ihre Herstellung und Anwendung in der Diagnostik und Therapie
US5891108A (en) * 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
US5869127A (en) * 1995-02-22 1999-02-09 Boston Scientific Corporation Method of providing a substrate with a bio-active/biocompatible coating
CA2213403C (en) 1995-02-22 2007-01-16 Menlo Care, Inc. Covered expanding mesh stent
US5605696A (en) 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
US5609629A (en) 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US5830879A (en) * 1995-10-02 1998-11-03 St. Elizabeth's Medical Center Of Boston, Inc. Treatment of vascular injury using vascular endothelial growth factor
US6283951B1 (en) * 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US6234951B1 (en) * 1996-02-29 2001-05-22 Scimed Life Systems, Inc. Intravascular radiation delivery system
US5855546A (en) * 1996-02-29 1999-01-05 Sci-Med Life Systems Perfusion balloon and radioactive wire delivery system
US6099454A (en) * 1996-02-29 2000-08-08 Scimed Life Systems, Inc. Perfusion balloon and radioactive wire delivery system
US5977163A (en) * 1996-03-12 1999-11-02 Pg-Txl Company, L. P. Water soluble paclitaxel prodrugs
DE19614136A1 (de) * 1996-04-10 1997-10-16 Inst Neue Mat Gemein Gmbh Verfahren zur Herstellung agglomeratfreier nanoskaliger Eisenoxidteilchen mit hydrolysebeständigem Überzug
ES2248847T3 (es) * 1996-05-24 2006-03-16 Angiotech Pharmaceuticals, Inc. Composiciones y metodos para tratar o prevenir enfermedades de las vias de conduccion del cuerpo.
US5830217A (en) * 1996-08-09 1998-11-03 Thomas J. Fogarty Soluble fixation device and method for stent delivery catheters
US6511477B2 (en) * 1997-03-13 2003-01-28 Biocardia, Inc. Method of drug delivery to interstitial regions of the myocardium
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern
US5902299A (en) * 1997-07-29 1999-05-11 Jayaraman; Swaminathan Cryotherapy method for reducing tissue injury after balloon angioplasty or stent implantation
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
JP2001514936A (ja) 1997-08-13 2001-09-18 ボストン サイエンティフィック コーポレイション 水不溶性薬剤の装填および放出
US5854382A (en) * 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
US5971979A (en) * 1997-12-02 1999-10-26 Odyssey Technologies, Inc. Method for cryogenic inhibition of hyperplasia
US6093463A (en) * 1997-12-12 2000-07-25 Intella Interventional Systems, Inc. Medical devices made from improved polymer blends
US6364856B1 (en) * 1998-04-14 2002-04-02 Boston Scientific Corporation Medical device with sponge coating for controlled drug release
US6240407B1 (en) * 1998-04-29 2001-05-29 International Business Machines Corp. Method and apparatus for creating an index in a database system
CA2340652C (en) * 1998-08-20 2013-09-24 Cook Incorporated Coated implantable medical device comprising paclitaxel
US6432102B2 (en) * 1999-03-15 2002-08-13 Cryovascular Systems, Inc. Cryosurgical fluid supply
US6514245B1 (en) * 1999-03-15 2003-02-04 Cryovascular Systems, Inc. Safety cryotherapy catheter
US6468297B1 (en) * 1999-02-24 2002-10-22 Cryovascular Systems, Inc. Cryogenically enhanced intravascular interventions
AU778081B2 (en) * 1999-03-25 2004-11-11 Tepha, Inc. Medical devices and applications of polyhydroxyalkanoate polymers
US6186745B1 (en) * 1999-04-28 2001-02-13 Chemand Corporation Gas pressurized liquid pump with intermediate chamber
US6203551B1 (en) * 1999-10-04 2001-03-20 Advanced Cardiovascular Systems, Inc. Chamber for applying therapeutic substances to an implant device
US6733513B2 (en) * 1999-11-04 2004-05-11 Advanced Bioprosthetic Surfaces, Ltd. Balloon catheter having metal balloon and method of making same
US6418448B1 (en) * 1999-12-06 2002-07-09 Shyam Sundar Sarkar Method and apparatus for processing markup language specifications for data and metadata used inside multiple related internet documents to navigate, query and manipulate information from a plurality of object relational databases over the web
US6527740B1 (en) * 1999-12-22 2003-03-04 Advanced Cardiovascular Systems, Inc. Medical regrooming and drug delivery device
US7166098B1 (en) * 1999-12-30 2007-01-23 Advanced Cardiovascular Systems, Inc. Medical assembly with transducer for local delivery of a therapeutic substance and method of using same
DE10031740A1 (de) * 2000-06-29 2002-02-14 Sanguibio Tech Ag Künstliche Sauerstoffträger aus vernetztem modifizierten Human- oder Schweinehämoglobin mit verbesserten Eigenschaften, Verfahren zu ihrer technisch einfachen Herstellung aus gereinigtem Material in hohen Ausbeuten, sowie deren Verwendung
DE10031742A1 (de) * 2000-06-29 2002-01-17 Sanguibio Tech Ag Verfahren zur Herstellung künstlicher Sauerstoffträger aus kovalent vernetzten Hämoglobinen mit verbesserten funktionellen Eigenschaften durch Vernetzung in Anwesenheit chemisch nicht reagierender Effektoren der Sauerstoffaffinität der Hämoglobine
JP5178984B2 (ja) * 2000-07-24 2013-04-10 グレイゼル、ジェフリー 拡張術およびステント術用の補剛バルーン・カテーテル
US6602246B1 (en) * 2000-08-18 2003-08-05 Cryovascular Systems, Inc. Cryotherapy method for detecting and treating vulnerable plaque
US6863861B1 (en) * 2000-09-28 2005-03-08 Boston Scientific Scimed, Inc. Process for forming a medical device balloon
US6545097B2 (en) * 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US7179251B2 (en) * 2001-01-17 2007-02-20 Boston Scientific Scimed, Inc. Therapeutic delivery balloon
US7247338B2 (en) * 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
US7682387B2 (en) * 2002-04-24 2010-03-23 Biosensors International Group, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US7160317B2 (en) * 2002-01-04 2007-01-09 Boston Scientific Scimed, Inc. Multiple-wing balloon catheter to reduce damage to coated expandable medical implants
WO2003061731A2 (en) * 2002-01-22 2003-07-31 Endobionics, Inc. Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia
US7186237B2 (en) * 2002-02-14 2007-03-06 Avantec Vascular Corporation Ballon catheter for creating a longitudinal channel in a lesion and method
US7762995B2 (en) * 2002-04-25 2010-07-27 The Board Of Trustees Of The Leland Stanford Junior University Expandable guide sheath and apparatus and methods using such sheaths
US7105175B2 (en) * 2002-06-19 2006-09-12 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
CA2484383C (en) * 2002-07-12 2016-05-31 Cook Incorporated Medical device coated with a bioactive agent
US7037319B2 (en) * 2002-10-15 2006-05-02 Scimed Life Systems, Inc. Nanotube paper-based medical device
DE10253634A1 (de) * 2002-11-13 2004-05-27 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Endoprothese
US20060121080A1 (en) * 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
US20040117222A1 (en) * 2002-12-14 2004-06-17 International Business Machines Corporation System and method for evaluating information aggregates by generation of knowledge capital
US7686824B2 (en) * 2003-01-21 2010-03-30 Angioscore, Inc. Apparatus and methods for treating hardened vascular lesions
WO2004089958A2 (en) * 2003-03-31 2004-10-21 TEVA Gyógyszergyár Részvénytársaság Crystallization and purification of macrolides
US7060062B2 (en) * 2003-06-04 2006-06-13 Cryo Vascular Systems, Inc. Controllable pressure cryogenic balloon treatment system and method
JP2005022590A (ja) * 2003-07-01 2005-01-27 Nissan Motor Co Ltd 車両用表示装置
US20050025848A1 (en) * 2003-07-30 2005-02-03 Ruey-Fa Huang Air filter shaping mold
US8740844B2 (en) * 2003-08-20 2014-06-03 Boston Scientific Scimed, Inc. Medical device with drug delivery member
US20050129731A1 (en) * 2003-11-03 2005-06-16 Roland Horres Biocompatible, biostable coating of medical surfaces
US20100030183A1 (en) * 2004-03-19 2010-02-04 Toner John L Method of treating vascular disease at a bifurcated vessel using a coated balloon
US20070027523A1 (en) * 2004-03-19 2007-02-01 Toner John L Method of treating vascular disease at a bifurcated vessel using coated balloon
US8431145B2 (en) * 2004-03-19 2013-04-30 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
US9555223B2 (en) * 2004-03-23 2017-01-31 Medtronic Cryocath Lp Method and apparatus for inflating and deflating balloon catheters
US20050226991A1 (en) * 2004-04-07 2005-10-13 Hossainy Syed F Methods for modifying balloon of a catheter assembly
US7070576B2 (en) * 2004-04-30 2006-07-04 Boston Scientific Scimed, Inc. Directional cutting balloon
US7753876B2 (en) * 2004-05-10 2010-07-13 Medtronic Vascular, Inc. Expandable jaw drug delivery catheter
US20060013853A1 (en) * 2004-07-19 2006-01-19 Richard Robert E Medical devices having conductive substrate and covalently bonded coating layer
US7771740B2 (en) * 2004-07-19 2010-08-10 Boston Scientific Scimed, Inc. Medical devices containing copolymers with graft copolymer endblocks for drug delivery
US20060025848A1 (en) * 2004-07-29 2006-02-02 Jan Weber Medical device having a coating layer with structural elements therein and method of making the same
US7758541B2 (en) * 2004-08-17 2010-07-20 Boston Scientific Scimed, Inc. Targeted drug delivery device and method
US8396548B2 (en) * 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US8361490B2 (en) * 2004-09-16 2013-01-29 Theracoat Ltd. Biocompatible drug delivery apparatus and methods
US7470252B2 (en) * 2004-09-16 2008-12-30 Boston Scientific Scimed, Inc. Expandable multi-port therapeutic delivery system
US20060069385A1 (en) * 2004-09-28 2006-03-30 Scimed Life Systems, Inc. Methods and apparatus for tissue cryotherapy
US8312836B2 (en) * 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
WO2006037049A2 (en) * 2004-09-28 2006-04-06 Atrium Medical Corporation Application of a coating on a medical device
US20060083768A1 (en) * 2004-09-28 2006-04-20 Atrium Medical Corporation Method of thickening a coating using a drug
US7491188B2 (en) * 2004-10-12 2009-02-17 Boston Scientific Scimed, Inc. Reinforced and drug-eluting balloon catheters and methods for making same
US20060085058A1 (en) * 2004-10-20 2006-04-20 Rosenthal Arthur L System and method for delivering a biologically active material to a body lumen
CA2584358A1 (en) * 2004-12-01 2006-06-08 Teva Gyogyszergyar Zartkoeruen Mukoedo Reszvenytarsasag Non-hygroscopic and powdery amorphous pimecrolimus
US7658744B2 (en) * 2004-12-03 2010-02-09 Boston Scientific Scimed, Inc. Multiple balloon catheter
US7698270B2 (en) * 2004-12-29 2010-04-13 Baynote, Inc. Method and apparatus for identifying, extracting, capturing, and leveraging expertise and knowledge
US8221824B2 (en) * 2005-02-03 2012-07-17 Boston Scientific Scimed, Inc. Deforming surface of drug eluting coating to alter drug release profile of a medical device
US20060184191A1 (en) * 2005-02-11 2006-08-17 Boston Scientific Scimed, Inc. Cutting balloon catheter having increased flexibility regions
US8048028B2 (en) * 2005-02-17 2011-11-01 Boston Scientific Scimed, Inc. Reinforced medical balloon
US7527604B2 (en) * 2005-03-09 2009-05-05 Boston Scientific Scimed, Inc. Rotatable multi-port therapeutic delivery device
KR20080008364A (ko) * 2005-05-05 2008-01-23 헤모텍 아게 관 스텐트의 전면 코팅
CN1317920C (zh) * 2005-06-15 2007-05-23 华为技术有限公司 一种睡眠模式下业务指示消息发送方法
US8722074B2 (en) * 2005-07-19 2014-05-13 Boston Scientific Scimed, Inc. Medical devices containing radiation resistant polymers
US20070078413A1 (en) * 2005-08-25 2007-04-05 Stenzel Eric B Medical device having a lubricant
US20070067882A1 (en) * 2005-09-21 2007-03-22 Liliana Atanasoska Internal medical devices having polyelectrolyte-containing extruded regions
US9440003B2 (en) * 2005-11-04 2016-09-13 Boston Scientific Scimed, Inc. Medical devices having particle-containing regions with diamond-like coatings
US8137735B2 (en) * 2005-11-10 2012-03-20 Allegiance Corporation Elastomeric article with antimicrobial coating
US7693836B2 (en) * 2005-12-27 2010-04-06 Baynote, Inc. Method and apparatus for determining peer groups based upon observed usage patterns
KR100673023B1 (ko) * 2005-12-28 2007-01-24 삼성전자주식회사 파이프라인-버퍼 방식으로 프로그램되는 반도체 메모리장치
US8431060B2 (en) * 2006-01-31 2013-04-30 Abbott Cardiovascular Systems Inc. Method of fabricating an implantable medical device using gel extrusion and charge induced orientation
EP3150236B1 (de) * 2006-02-09 2018-12-26 B. Braun Melsungen AG Faltenballonbeschichtungsverfahren
US8518105B2 (en) * 2006-03-24 2013-08-27 Abbott Cardiovascular System Inc. Methods and apparatuses for coating a lesion
CA2656635C (en) * 2006-07-03 2013-05-28 Hemoteq Ag Stent with polymeric coating comprising rapamycin as an active agent
US7820812B2 (en) * 2006-07-25 2010-10-26 Abbott Laboratories Methods of manufacturing crystalline forms of rapamycin analogs
US20080027421A1 (en) * 2006-07-27 2008-01-31 Vancelette David W CryoBalloon Treatment for Postpartum Hemorrhage
US20080057102A1 (en) * 2006-08-21 2008-03-06 Wouter Roorda Methods of manufacturing medical devices for controlled drug release
US7897170B2 (en) * 2006-08-25 2011-03-01 Boston Scientific Scimed, Inc. Medical devices having improved mechanical performance
US20080050415A1 (en) * 2006-08-25 2008-02-28 Boston Scientic Scimed, Inc. Polymeric/ceramic composite materials for use in medical devices
CA2663559A1 (en) * 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
JP2010503482A (ja) * 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド 内部人工器官
US20080095847A1 (en) * 2006-10-18 2008-04-24 Thierry Glauser Stimulus-release carrier, methods of manufacture and methods of treatment
US20080175887A1 (en) * 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
EP2101779A1 (de) * 2006-12-13 2009-09-23 Angiotech Pharmaceuticals, Inc. Medizinische implantate mit einer kombination von verbindungen
DE102007008479A1 (de) * 2007-02-21 2008-09-04 Orlowski, Michael, Dr. Beschichtetes Expandierbares System
US9370642B2 (en) * 2007-06-29 2016-06-21 J.W. Medical Systems Ltd. Adjustable-length drug delivery balloon
US9192697B2 (en) * 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US8690823B2 (en) * 2007-07-13 2014-04-08 Abbott Cardiovascular Systems Inc. Drug coated balloon catheter
US8070798B2 (en) * 2007-07-20 2011-12-06 Josiah Wilcox Drug eluting medical device and method
EP2200674A2 (de) * 2007-09-10 2010-06-30 Boston Scientific Scimed, Inc. Medizinische vorrichtungen mit auslösbarem bioadhäsivem material
US8100855B2 (en) * 2007-09-17 2012-01-24 Abbott Cardiovascular Systems, Inc. Methods and devices for eluting agents to a vessel
US20090105687A1 (en) * 2007-10-05 2009-04-23 Angioscore, Inc. Scoring catheter with drug delivery membrane
US7863387B2 (en) * 2007-10-25 2011-01-04 Boston Scientific Scimed, Inc. Dehydrofluorination and surface modification of fluoropolymers for drug delivery applications
US20090112239A1 (en) * 2007-10-31 2009-04-30 Specialized Vascular Technologies, Inc. Sticky dilatation balloon and methods of using
US20100049294A1 (en) * 2008-06-04 2010-02-25 Zukowski Stanislaw L Controlled deployable medical device and method of making the same
US8187221B2 (en) * 2008-07-11 2012-05-29 Nexeon Medsystems, Inc. Nanotube-reinforced balloons for delivering therapeutic agents within or beyond the wall of blood vessels, and methods of making and using same
EP2313122B1 (de) * 2008-07-17 2019-03-06 Micell Technologies, Inc. Medizinische wirkstofffreisetzungsvorrichtung
US7774125B2 (en) * 2008-08-06 2010-08-10 Fluid Control Products, Inc. Programmable fuel pump control
US8133199B2 (en) * 2008-08-27 2012-03-13 Boston Scientific Scimed, Inc. Electroactive polymer activation system for a medical device
WO2010024898A2 (en) * 2008-08-29 2010-03-04 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US8187222B2 (en) * 2008-09-12 2012-05-29 Boston Scientific Scimed, Inc. Devices and systems for delivery of therapeutic agents to body lumens
WO2010042471A2 (en) * 2008-10-07 2010-04-15 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents to body lumens
EP2944332B1 (de) * 2009-07-10 2016-08-17 Boston Scientific Scimed, Inc. Verwendung von nanokristallen für einen wirkstofffreisetzungsballon
EP2453938B1 (de) * 2009-07-17 2015-08-19 Boston Scientific Scimed, Inc. Nukleierung von wirkstofffreisetzungsballons für verbesserte kristallgrösse und -dichte
US8424498B2 (en) * 2009-07-23 2013-04-23 Briggs & Stratton Corporation Engine blower scroll
US20110054396A1 (en) * 2009-08-27 2011-03-03 Boston Scientific Scimed, Inc. Balloon Catheter Devices With Drug-Coated Sheath
US8617136B2 (en) * 2009-08-31 2013-12-31 Boston Scientific Scimed, Inc. Balloon catheter devices with drug delivery extensions
EP2488243A1 (de) * 2009-10-14 2012-08-22 Boston Scientific Scimed, Inc. Ballonkatheter mit formgedächtnisschleuse zur freisetzung eines therapeutikums
US8366661B2 (en) * 2009-12-18 2013-02-05 Boston Scientific Scimed, Inc. Medical device with expandable body for drug delivery by capsules
WO2011090569A1 (en) * 2009-12-30 2011-07-28 Boston Scientific Scimed, Inc. Drug-delivery balloons
US20110160645A1 (en) * 2009-12-31 2011-06-30 Boston Scientific Scimed, Inc. Cryo Activated Drug Delivery and Cutting Balloons
EP2915556A1 (de) * 2010-01-21 2015-09-09 Boston Scientific Scimed, Inc. Ballonkatheter mit therapeutischen wirkstoffen in ballonfaltungen und verfahren zu ihrer herstellung
EP2629832A1 (de) * 2010-10-18 2013-08-28 Boston Scientific Scimed, Inc. Medikamentenbeschichtetes medizinprodukt mit bioklebstoffen

Also Published As

Publication number Publication date
EP1121162A1 (de) 2001-08-08
US20060002973A1 (en) 2006-01-05
WO2000021584A1 (en) 2000-04-20
US6306166B1 (en) 2001-10-23
AU1108800A (en) 2000-05-01
US20020037358A1 (en) 2002-03-28
US20110196340A1 (en) 2011-08-11
EP1121162B1 (de) 2007-03-21
US20120239001A1 (en) 2012-09-20
EP1800702A3 (de) 2008-03-05
US20130304029A1 (en) 2013-11-14
US20080021385A1 (en) 2008-01-24
EP1800702A2 (de) 2007-06-27
DE69935605D1 (de) 2007-05-03
DE69935605T2 (de) 2007-11-29

Similar Documents

Publication Publication Date Title
DE69935605D1 (de) Ladung und abgabe von wasser unlöslicher arzneimittel
ATE344063T1 (de) Beschichtete medizinische geräte
ATE343969T1 (de) Beschichtete medizinische geräte
DE602004019224D1 (de) Herstellung von langzeit-arzneimittelabgabevorrichtungen mit polymeren auf polyurethanbasis
ATE432096T1 (de) Beschichtete gefässvorrichtungen
ATE361093T1 (de) Selektiv auf die leber wirkende pharmazeutisch aktive substanz
EP2196226A3 (de) Beschichtete medizinische Geräte
HUP9904174A2 (hu) Bőrön át történő adagoláshoz szánt gyógyszerkészítmények
MA26061A1 (fr) Dispositifs transdermiques de delivrance de medicaments avec microprotuberances enrobees
DE69121881D1 (de) Hautelektrodenaufbau und dazugehöriges gerät zur transdermalen verabreichung von heilmitteln
PT740650E (pt) Co-farmacos como um metodo de administracao controlada de farmacos
DE69638364D1 (de) Formulierungen mit kontrollierter abgabe (albuterol)
ATE358505T1 (de) Beschichtete endovaskuläre vorrichtung
DK0861659T3 (da) Indretninger til administration af lægemidler med forsinket frigivelse
BR0007974A (pt) Usos de um agente farmacologicamente ativo, deum constructo de gene e de um antìgeno, métodospara produzir uma composição farmacêutica em póe para administrar uma droga a um indivìduo emnecessidade dela, composição farmacêutica, formade dosagem unitária, e, artigo de manufatura parasuprimento transdérmico ou transmucoso de umagente farmacologicamente ativo a um indivìduo
AU6158101A (en) Delivery devices for treatment of vascular disease
MX9308184A (es) Sistema de administracion controlado, plastificado, capaz de erosionarse biologicamente.
NO884474L (no) Implanterbart, biologisk nedbrytbart virkestoff-frigjoeringssystem.
CO4910114A1 (es) Formulaciones farmaceuticas para suministro de droga soste- nido
DE60112777D1 (de) Beschichtete medizinische geräte und verfahren zur sterilisation
GR3030732T3 (en) Pharmaceutical compositions including a drug, a cross-linked polymeric substance, an oil, and a surface active agent.
WO2004012676A3 (en) Drug-loaded biological material chemically treated with genipin
ATE292453T1 (de) Antivirale arznei
ATE469644T1 (de) Pharmazeutische zubereitung enthaltend n-ä2-(1,6, 7,8-tetrahydro-2h-indenoä5,4 büfuran-8- yl)ethylüpropionamid ummantelt mit einer copolyvidon-enthaltenden, polyäthylenglykolfreien umhüllung
SE9301877D0 (sv) In situ gel for therapeutic use

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties