ATE357442T1 - Verfahren zur herstellung von candesartan cilexetil - Google Patents
Verfahren zur herstellung von candesartan cilexetilInfo
- Publication number
- ATE357442T1 ATE357442T1 AT04795674T AT04795674T ATE357442T1 AT E357442 T1 ATE357442 T1 AT E357442T1 AT 04795674 T AT04795674 T AT 04795674T AT 04795674 T AT04795674 T AT 04795674T AT E357442 T1 ATE357442 T1 AT E357442T1
- Authority
- AT
- Austria
- Prior art keywords
- candesartan cilexetil
- cilexetil
- reaction
- producing
- producing candesartan
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51256603P | 2003-10-16 | 2003-10-16 | |
| US52352403P | 2003-11-18 | 2003-11-18 | |
| US53799504P | 2004-01-21 | 2004-01-21 | |
| US56864904P | 2004-05-05 | 2004-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE357442T1 true ATE357442T1 (de) | 2007-04-15 |
Family
ID=34468494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04795674T ATE357442T1 (de) | 2003-10-16 | 2004-10-18 | Verfahren zur herstellung von candesartan cilexetil |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7098342B2 (de) |
| EP (1) | EP1685126B1 (de) |
| AT (1) | ATE357442T1 (de) |
| CA (1) | CA2542499A1 (de) |
| DE (1) | DE602004005488T2 (de) |
| ES (1) | ES2284068T3 (de) |
| IL (1) | IL174868A0 (de) |
| PT (1) | PT1685126E (de) |
| WO (1) | WO2005037821A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7692023B2 (en) | 2004-02-11 | 2010-04-06 | Teva Pharmaceutical Industries Ltd. | Candesartan cilexetil polymorphs |
| CA2590894A1 (en) * | 2005-01-14 | 2006-07-20 | Teva Pharmaceutical Industries Ltd. | Preparation of crude candesartan cilexetil |
| CN100400536C (zh) * | 2005-04-30 | 2008-07-09 | 重庆圣华曦药业有限公司 | 坎地沙坦酯c-型晶体的制备方法 |
| AR053517A1 (es) * | 2005-06-06 | 2007-05-09 | Medichem Sa | Proceso para la preparacion de compuestos de tetrazolilo, uso de los mismos en el tratamiento de enfermedades circulatorias y formulaciones farmaceuticas que los contienen. |
| SI22127A (sl) | 2005-10-07 | 2007-04-30 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Postopek za pripravo kandesartan cileksetila |
| CZ302240B6 (cs) * | 2006-03-16 | 2011-01-05 | Zentiva, A. S | Zpusob odstranování trifenylmethanové chránicí skupiny u prekursoru antihypertensiv majících labilní, metabolicky odbouratelnou skupinu |
| EP2049510A1 (de) * | 2006-07-28 | 2009-04-22 | Krka Tovarna Zdravil, D.D., Novo Mesto | Verfahren zur herstellung von candesartandilexetil form i |
| KR100995755B1 (ko) | 2008-10-31 | 2010-11-19 | 일동제약주식회사 | 트리틸 칸데사르탄 실렉세틸의 개선된 제조방법 |
| WO2011080684A1 (en) | 2009-12-31 | 2011-07-07 | Ranbaxy Laboratories Limited | Process for the preparation of candesartan cilexetil |
| WO2011092666A1 (en) | 2010-01-29 | 2011-08-04 | Ranbaxy Laboratories Limited | An improved process for the preparation of candesartan cilexetil, polymorphic forms of n-trityl candesartan and their uses thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4151273A (en) * | 1974-10-31 | 1979-04-24 | The Regents Of The University Of California | Increasing the absorption rate of insoluble drugs |
| FR2408345A1 (fr) * | 1976-11-30 | 1979-06-08 | Besins Jean Louis | Nouvelle composition a action anti-conceptionnelle |
| US4302446A (en) * | 1979-10-02 | 1981-11-24 | Bristol-Myers Company | Pharmaceutical compositions |
| SE457326B (sv) * | 1986-02-14 | 1988-12-19 | Lejus Medical Ab | Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa |
| IL95975A (en) * | 1989-10-24 | 1997-06-10 | Takeda Chemical Industries Ltd | N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them |
| US5196444A (en) * | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
| US5703110A (en) * | 1990-04-27 | 1997-12-30 | Takeda Chemical Industries, Ltd. | Benzimidazole derivatives, their production and use |
| US6004989A (en) * | 1990-04-27 | 1999-12-21 | Takeda Chemical Industries, Ltd. | Benzimidazole derivatives, their production and use |
| RU1836357C (ru) * | 1990-07-23 | 1993-08-23 | Др.Карл Томэ ГмбХ | Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами |
| DE4023369A1 (de) | 1990-07-23 | 1992-01-30 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5210206A (en) * | 1990-09-10 | 1993-05-11 | Abbott Laboratories | 1,3-oxazolyl substituted biphenyl |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| US5271944A (en) * | 1991-04-05 | 1993-12-21 | Biofor, Ltd. | Pharmacologically enhanced formulations |
| TW284688B (de) * | 1991-11-20 | 1996-09-01 | Takeda Pharm Industry Co Ltd | |
| EP0550313A1 (de) * | 1991-12-30 | 1993-07-07 | Synthelabo | 2-(Tetranol-5-yl)-(1,1'-Biphenyl)derivate, ihre Herstellung und Anwendung als Zwischenverbindungen |
| DE69304709T2 (de) * | 1992-10-14 | 1997-01-23 | Unilever N.V., Rotterdam | Salatsosse |
| US5281604A (en) * | 1993-04-23 | 1994-01-25 | American Cyanamid Company | Angiotensin II receptor blocking 2,3,6-substituted quinazolinones |
| US5721263A (en) * | 1993-06-07 | 1998-02-24 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition for angiotensin II-mediated diseases |
| US5298517A (en) * | 1993-10-07 | 1994-03-29 | American Cyanamid Company | Angiotensin II receptor blocking agents |
| EP0668272B1 (de) | 1994-01-28 | 2000-07-12 | Takeda Chemical Industries, Ltd. | Ein Verfahren zur Herstellung von Tetrazolyl-Verbindungen |
| US6177587B1 (en) | 1997-05-26 | 2001-01-23 | Takeda Chemical Industries, Ltd. | Production method of aminobenzene compound |
| SE9901667D0 (sv) * | 1999-05-07 | 1999-05-07 | Astra Ab | Method and device for forming particles |
| CA2453890A1 (en) | 2001-08-03 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Crystal and process for producing the same |
| CA2594332A1 (en) * | 2005-01-06 | 2006-07-13 | Elan Pharma International Ltd. | Nanoparticulate candesartan formulations |
-
2004
- 2004-10-18 DE DE602004005488T patent/DE602004005488T2/de not_active Revoked
- 2004-10-18 ES ES04795674T patent/ES2284068T3/es not_active Expired - Lifetime
- 2004-10-18 AT AT04795674T patent/ATE357442T1/de not_active IP Right Cessation
- 2004-10-18 US US10/968,710 patent/US7098342B2/en not_active Expired - Fee Related
- 2004-10-18 CA CA002542499A patent/CA2542499A1/en not_active Abandoned
- 2004-10-18 WO PCT/US2004/034540 patent/WO2005037821A2/en not_active Ceased
- 2004-10-18 PT PT04795674T patent/PT1685126E/pt unknown
- 2004-10-18 EP EP04795674A patent/EP1685126B1/de not_active Revoked
-
2006
- 2006-04-09 IL IL174868A patent/IL174868A0/en unknown
- 2006-07-12 US US11/485,714 patent/US20060252939A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL174868A0 (en) | 2006-08-20 |
| US20060252939A1 (en) | 2006-11-09 |
| ES2284068T3 (es) | 2007-11-01 |
| EP1685126B1 (de) | 2007-03-21 |
| CA2542499A1 (en) | 2005-04-28 |
| US7098342B2 (en) | 2006-08-29 |
| WO2005037821A3 (en) | 2005-06-02 |
| DE602004005488T2 (de) | 2007-11-29 |
| DE602004005488D1 (de) | 2007-05-03 |
| US20050131037A1 (en) | 2005-06-16 |
| WO2005037821A2 (en) | 2005-04-28 |
| PT1685126E (pt) | 2007-04-30 |
| EP1685126A2 (de) | 2006-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |