ATE358674T1 - 4-tetrazolyl-4-phenylpiperidindervate zur schmerzbehandlung - Google Patents

4-tetrazolyl-4-phenylpiperidindervate zur schmerzbehandlung

Info

Publication number
ATE358674T1
ATE358674T1 AT03789796T AT03789796T ATE358674T1 AT E358674 T1 ATE358674 T1 AT E358674T1 AT 03789796 T AT03789796 T AT 03789796T AT 03789796 T AT03789796 T AT 03789796T AT E358674 T1 ATE358674 T1 AT E358674T1
Authority
AT
Austria
Prior art keywords
tetrazolyl
pain treatment
phenylpiperidine derivatives
phenylpiperidine
derivatives
Prior art date
Application number
AT03789796T
Other languages
English (en)
Inventor
Zhengming Chen
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of ATE358674T1 publication Critical patent/ATE358674T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT03789796T 2002-11-18 2003-11-17 4-tetrazolyl-4-phenylpiperidindervate zur schmerzbehandlung ATE358674T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42738102P 2002-11-18 2002-11-18
US46027803P 2003-04-03 2003-04-03
US48848803P 2003-07-17 2003-07-17
US10/714,066 US7202259B2 (en) 2002-11-18 2003-11-13 Therapeutic agents useful for treating pain

Publications (1)

Publication Number Publication Date
ATE358674T1 true ATE358674T1 (de) 2007-04-15

Family

ID=32777221

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03789796T ATE358674T1 (de) 2002-11-18 2003-11-17 4-tetrazolyl-4-phenylpiperidindervate zur schmerzbehandlung
AT07006697T ATE402167T1 (de) 2002-11-18 2003-11-17 4-tetrazolyl-4-phenylpiperidinderivate zur schmerzbehandlung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT07006697T ATE402167T1 (de) 2002-11-18 2003-11-17 4-tetrazolyl-4-phenylpiperidinderivate zur schmerzbehandlung

Country Status (36)

Country Link
US (3) US7202259B2 (de)
EP (2) EP1803718B1 (de)
JP (2) JP4601429B2 (de)
KR (1) KR20050115221A (de)
CN (2) CN101648941A (de)
AP (1) AP2210A (de)
AR (1) AR047008A1 (de)
AT (2) ATE358674T1 (de)
AU (2) AU2003294313B2 (de)
BR (1) BR0316305A (de)
CA (1) CA2506242C (de)
CO (1) CO5690588A2 (de)
CR (2) CR7877A (de)
CY (2) CY1107682T1 (de)
DE (2) DE60322451D1 (de)
DK (2) DK1562932T3 (de)
EA (1) EA008621B1 (de)
EC (1) ECSP055840A (de)
ES (2) ES2312150T3 (de)
GE (1) GEP20084539B (de)
IL (1) IL209352A0 (de)
IS (2) IS2720B (de)
MA (1) MA27565A1 (de)
ME (1) MEP48108A (de)
MX (1) MXPA05004669A (de)
MY (1) MY135647A (de)
NI (1) NI200500087A (de)
NO (1) NO20052894L (de)
NZ (2) NZ572685A (de)
OA (1) OA13010A (de)
PT (2) PT1803718E (de)
RS (1) RS51047B (de)
SG (1) SG165998A1 (de)
SI (2) SI1562932T1 (de)
TW (2) TWI343917B (de)
WO (1) WO2004046132A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7202259B2 (en) * 2002-11-18 2007-04-10 Euro-Celtique S.A. Therapeutic agents useful for treating pain
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
AR047936A1 (es) 2003-04-30 2006-03-15 Purdue Pharma Ltd Forma de dosificacion transdermica resistente a la manipulacion
WO2005075455A2 (en) 2004-01-30 2005-08-18 Euro-Celtique S.A. Methods for making 4-tetrazolyl-4-phenylpiperidine compounds
SE0401656D0 (sv) * 2004-06-24 2004-06-24 Astrazeneca Ab Chemical compounds
EA013510B1 (ru) * 2005-11-21 2010-06-30 Пэдью Фарма Л.П. Соединения 4-оксадиазолилпиперидина и их применение
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
US8771693B2 (en) 2009-10-27 2014-07-08 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
CA2810356C (en) 2010-09-21 2016-06-14 Purdue Pharma L.P. Buprenorphine analogs
CN102648915B (zh) * 2011-02-28 2015-04-15 鲁南制药集团股份有限公司 一种治疗或预防神经病理性疼痛的药物组合物
WO2012149334A2 (en) 2011-04-27 2012-11-01 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
US10138207B2 (en) 2012-11-09 2018-11-27 Purdue Pharma, L.P. Benzomorphan analogs and the use thereof
EP2931729B1 (de) 2012-12-07 2019-02-06 Purdue Pharma LP Buprenorphinanaloga als opiodrezeptormodulatoren
WO2014091297A1 (en) 2012-12-14 2014-06-19 Purdue Pharma L.P. Spirocyclic morphinans and their use
ES2631197T3 (es) 2012-12-14 2017-08-29 Purdue Pharma Lp Análogos de piridonamorfinano y actividad biológica sobre los receptores opiodes
CA2900023A1 (en) 2013-01-31 2014-08-07 Purdue Pharma L.P. Benzomorphan analogs and the use thereof
US8969358B2 (en) 2013-03-15 2015-03-03 Purdue Pharma L.P. Buprenorphine analogs
EP3087073B1 (de) 2013-12-26 2018-07-04 Purdue Pharma LP 10-substituierte morphinanhydantoine
US9656962B2 (en) 2013-12-26 2017-05-23 Purdue Pharma L.P. Ring-contracted morphinans and the use thereof
US9340542B2 (en) 2013-12-26 2016-05-17 Purdue Pharma L.P. Propellane-based compounds and the use thereof
US9862726B2 (en) 2013-12-26 2018-01-09 Purdue Pharma L.P. Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans
EP3087078B1 (de) 2013-12-26 2019-05-15 Purdue Pharma LP 7-beta-alkyl-analoga von orvinolen
EP3086790A4 (de) 2013-12-27 2017-07-19 Purdue Pharma LP 6-substituierte und 7-substituierte morphinanaloge und verwendungen davon
EP3148535A4 (de) 2014-05-27 2017-11-29 Purdue Pharma LP Spirocyclische morphinane und verwendung davon
CA2951697A1 (en) 2014-06-13 2015-12-17 Purdue Pharma L.P. Azamophinan derivatives and use thereof
MA41125A (fr) 2014-12-05 2017-10-10 Purdue Pharma Lp Dérivés de 6.7-cyclomorphinane et leur utilisation
CA3018750A1 (en) 2016-03-22 2017-09-28 Regents Of The University Of Minnesota Combination for treating pain
CN119606965A (zh) 2016-07-29 2025-03-14 詹森药业有限公司 治疗前列腺癌的方法
WO2018125716A1 (en) 2017-01-02 2018-07-05 Purdue Pharma L.P. Morphinan derivatives and use thereof
CN117750958A (zh) * 2021-05-21 2024-03-22 普渡制药公司 治疗间质性膀胱炎/膀胱疼痛综合征的方法
JP2025521597A (ja) * 2022-06-24 2025-07-10 パーデュー、ファーマ、リミテッド、パートナーシップ 過活動膀胱症候群を治療または予防する方法

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) * 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
BE775611A (fr) 1970-11-24 1972-03-16 Synthelabo Derives de la (diphenyl-3,3 propyl-1)-1 piperidine, leur preparation etles medicaments qui en contiennent
US4076717A (en) * 1971-12-15 1978-02-28 G. D. Searle & Co. Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
DK162087D0 (da) * 1987-03-31 1987-03-31 Ferrosan As Piperidinforbindelser, deres fremstilling og anvendelse
US4831192A (en) * 1987-12-31 1989-05-16 Boc, Inc. Methods of preparing 4-heteropentacyclic-4-(N-phenyl)amido) piperidine derivatives and intermediate compounds
US5073543A (en) * 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) * 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5733566A (en) * 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5698155A (en) * 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5449989A (en) 1992-07-31 1995-09-12 Correa; Paulo N. Energy conversion system
US5736523A (en) 1992-11-09 1998-04-07 Biochem Pharma Inc. Antineoplastic heteronapthoquinones
US5606037A (en) 1992-11-09 1997-02-25 Biochem Pharma Inc. Processes antineoplastic heteronaphthoquinones
US5591767A (en) * 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US6166085A (en) 1995-04-14 2000-12-26 The Regents Of The University Of California Method of producing analgesia
US5849737A (en) 1995-04-14 1998-12-15 The Regents Of The University Of California Compositions and methods for treating pain
WO1996041626A1 (en) * 1995-06-12 1996-12-27 G.D. Searle & Co. Compositions comprising a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US5849761A (en) 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
AU1208397A (en) 1995-12-28 1997-07-28 Takeda Chemical Industries Ltd. Diphenylmethane derivatives as mip-1alpha/rantes receptor antagonists
US6221888B1 (en) 1997-05-29 2001-04-24 Merck & Co., Inc. Sulfonamides as cell adhesion inhibitors
EE03970B1 (et) * 1997-06-10 2003-02-17 Synthon B.V. 4-fenüülpiperidiinühend, selle valmistamine ja kasutamine ning seda sisaldav ravim
CN1291984A (zh) 1998-03-06 2001-04-18 詹森药业有限公司 甘氨酸传输抑制剂
US6423519B1 (en) * 1998-07-15 2002-07-23 Gpc Biotech Inc. Compositions and methods for inhibiting fungal growth
PE20001420A1 (es) 1998-12-23 2000-12-18 Pfizer Moduladores de ccr5
US7217714B1 (en) 1998-12-23 2007-05-15 Agouron Pharmaceuticals, Inc. CCR5 modulators
HUP0202248A3 (en) 1999-03-12 2006-06-28 Boehringer Ingelheim Pharma Compounds useful as anti-inflammatory agents
WO2001021169A1 (en) 1999-09-20 2001-03-29 Takeda Chemical Industries, Ltd. Mch antagonists
CA2324330A1 (en) 1999-11-08 2001-05-08 Ssp Co., Ltd. 4-hydroxy-4-phenylpiperidine derivatives and pharmaceuticals containing the same
EP1242085B1 (de) 1999-12-06 2005-08-24 Euro-Celtique, S.A. Benzimidazolverbindungen die nociceptinrezeptoraffinität haben
EP1244678A1 (de) 1999-12-22 2002-10-02 Merck Frosst Canada Inc. Phosphonsäurederivate als inhibitoren der protein tyrosin phosphatase 1b (ptp-1b)
US6608052B2 (en) 2000-02-16 2003-08-19 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as anti-inflammatory agents
US6703525B2 (en) 2000-02-16 2004-03-09 Boehringer Ingelheim Pharmaceuticals, Inc. Sulfonamide intermediates and methods of producing same
AU2001242744B2 (en) * 2000-03-24 2005-07-21 Meiji Seika Kaisha Ltd Diphenylalkylamine derivatives useful as opioid delta receptor ligands
US6544981B2 (en) 2000-06-09 2003-04-08 Bristol-Myers Squibb Company Lactam inhibitors of factor Xa and method
WO2002030896A1 (en) 2000-10-12 2002-04-18 Ssp Co., Ltd. 2,2-diphenylbutanamide derivatives and medicines containing the same
WO2002038185A2 (en) 2000-11-13 2002-05-16 Atrix Laboratories, Inc. Injectable sustained release delivery system with loperamide
US7202259B2 (en) * 2002-11-18 2007-04-10 Euro-Celtique S.A. Therapeutic agents useful for treating pain
WO2005075455A2 (en) * 2004-01-30 2005-08-18 Euro-Celtique S.A. Methods for making 4-tetrazolyl-4-phenylpiperidine compounds

Also Published As

Publication number Publication date
CY1108422T1 (el) 2014-04-09
AP2210A (en) 2011-02-25
AU2003294313A1 (en) 2004-06-15
JP2006525944A (ja) 2006-11-16
NO20052894D0 (no) 2005-06-14
KR20050115221A (ko) 2005-12-07
AU2003294313B2 (en) 2010-08-26
DE60322451D1 (de) 2008-09-04
ES2285235T3 (es) 2007-11-16
HK1086829A1 (zh) 2006-09-29
CA2506242A1 (en) 2004-06-03
JP2010163452A (ja) 2010-07-29
DE60313021D1 (de) 2007-05-16
DK1562932T3 (da) 2007-08-13
TW200418828A (en) 2004-10-01
EP1803718B1 (de) 2008-07-23
EP1562932B1 (de) 2007-04-04
OA13010A (en) 2006-11-10
US8026254B2 (en) 2011-09-27
IS2720B (is) 2011-02-15
SI1562932T1 (sl) 2007-08-31
IS8913A (is) 2010-07-21
CN101648941A (zh) 2010-02-17
IS7812A (is) 2005-04-19
CN100567288C (zh) 2009-12-09
US7202259B2 (en) 2007-04-10
MA27565A1 (fr) 2005-10-03
AU2010246411A1 (en) 2010-12-16
CR11037A (es) 2009-10-29
US20040152689A1 (en) 2004-08-05
DE60313021T2 (de) 2007-12-13
NO20052894L (no) 2005-06-14
PT1803718E (pt) 2008-09-26
TW200819436A (en) 2008-05-01
MY135647A (en) 2008-06-30
US20100069437A1 (en) 2010-03-18
ES2312150T3 (es) 2009-02-16
EA008621B1 (ru) 2007-06-29
BR0316305A (pt) 2005-09-27
ECSP055840A (es) 2005-08-11
EA200500726A1 (ru) 2005-10-27
JP4601429B2 (ja) 2010-12-22
ATE402167T1 (de) 2008-08-15
CY1107682T1 (el) 2013-04-18
SI1803718T1 (sl) 2008-12-31
NI200500087A (es) 2007-07-24
DK1803718T3 (da) 2008-10-27
AR047008A1 (es) 2006-01-04
US20070179141A1 (en) 2007-08-02
NZ572685A (en) 2010-06-25
NZ540068A (en) 2007-07-27
RS20050375A (sr) 2007-11-15
PT1562932E (pt) 2007-07-02
WO2004046132A1 (en) 2004-06-03
IL209352A0 (en) 2011-01-31
EP1803718A1 (de) 2007-07-04
CO5690588A2 (es) 2006-10-31
TWI343917B (en) 2011-06-21
SG165998A1 (en) 2010-11-29
US7687518B2 (en) 2010-03-30
CR7877A (es) 2005-11-30
EP1562932A1 (de) 2005-08-17
GEP20084539B (en) 2008-11-25
AP2005003297A0 (en) 2005-06-30
RS51047B (sr) 2010-10-31
EP1562932B9 (de) 2007-09-12
CA2506242C (en) 2011-07-05
CN1711256A (zh) 2005-12-21
MXPA05004669A (es) 2005-06-08
MEP48108A (en) 2011-02-10

Similar Documents

Publication Publication Date Title
ATE402167T1 (de) 4-tetrazolyl-4-phenylpiperidinderivate zur schmerzbehandlung
DE60328797D1 (de) Blutbehandlungsgerät
NO20035156L (no) Fremgangsmåter for brønnbehandling
AT6199U3 (de) Handgerät zur schmerzreduktion
DK1638502T3 (da) Dentalt behandlingselement
DE60311298D1 (de) Kopfhautbehandlung
ATE326842T1 (de) Zusammensetzung zur saatgutbehandlung
ATE389742T1 (de) Gewebebehandlungsmittel
NO20063443L (no) Piperziner effektive for behandling av smerte
DE60111520D1 (de) Hydroxyphenyl-piperazinyl-methyl-benzamid-derivate zur schmerzbehandlung
ATA13602003A (de) Therapeutisches behandlungsgerät
DE502004006513D1 (de) Rollnahtgeschweisster körper zur abgasbehandlung
DK1553950T3 (da) Terapeutisk behandling
PL1653982T3 (pl) Leczenie halitozy
DE60321507D1 (de) Katheter zur künstlichen Befruchtung
DE60221068D1 (de) Gerät zur tiefenwirksamen Hauttherapie
DE60312992D1 (de) Medizinisches implantat
BR0312187B1 (pt) método para o tratamento de sementes
DE60229887D1 (de) Oberflächenbehandlungssystem
ATE482707T1 (de) 1-ä2h-1-benzopyran-2-on-8-ylü- piperazin- derivate zur behandlung von schmerzen
DE60328516D1 (de) Thia-epothilon derivate zur krebsbehandlung
FI20021374A7 (fi) Jätevedenkäsittely-yksikkö
GB0211297D0 (en) Pain treatment
NO20042850L (no) Kreftbehandling
GB2432322B (en) Gel for tissue treatment

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1562932

Country of ref document: EP