ATE361366T1 - Aus bacillus stammende transglutaminase - Google Patents

Aus bacillus stammende transglutaminase

Info

Publication number
ATE361366T1
ATE361366T1 AT96101905T AT96101905T ATE361366T1 AT E361366 T1 ATE361366 T1 AT E361366T1 AT 96101905 T AT96101905 T AT 96101905T AT 96101905 T AT96101905 T AT 96101905T AT E361366 T1 ATE361366 T1 AT E361366T1
Authority
AT
Austria
Prior art keywords
transglutaminase
bacillus
transglutaminase derived
relates
bacilli
Prior art date
Application number
AT96101905T
Other languages
English (en)
Inventor
Katsunori Kobayashi
Shigeru Yamanaka
Kiyoshi Miwa
Shunichi Suzuki
Yuzuru Eto
Yuko Tanita
Kenzo Yokozeki
Kenichi Hashiguchi
Ajinomoto Ken
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE361366T1 publication Critical patent/ATE361366T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96101905T 1995-02-09 1996-02-09 Aus bacillus stammende transglutaminase ATE361366T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2196395 1995-02-09
JP22631695 1995-09-04
JP01307296A JP3669390B2 (ja) 1995-02-09 1996-01-29 バチルス属細菌由来のトランスグルタミナーゼ

Publications (1)

Publication Number Publication Date
ATE361366T1 true ATE361366T1 (de) 2007-05-15

Family

ID=27280100

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96101905T ATE361366T1 (de) 1995-02-09 1996-02-09 Aus bacillus stammende transglutaminase

Country Status (9)

Country Link
US (2) US5731183A (de)
EP (1) EP0726317B1 (de)
JP (1) JP3669390B2 (de)
KR (1) KR100358824B1 (de)
AT (1) ATE361366T1 (de)
AU (1) AU691714B2 (de)
CA (1) CA2169249A1 (de)
DE (1) DE69637054T2 (de)
TW (1) TW403785B (de)

Families Citing this family (60)

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EP0851029A4 (de) 1995-06-08 2001-05-23 Ajinomoto Kk Mikrobieller przess zur produktion von transglutaminase
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US6821763B2 (en) * 1997-07-04 2004-11-23 Ajinomoto Co., Inc. Process for producing microbial transglutaminase
DE69822251T2 (de) * 1997-07-04 2005-01-27 Ajinomoto Co., Inc. Verfahren zur Herstellung von mikrobieller Transglutaminase
DE19732917C1 (de) * 1997-07-30 1998-10-15 Fuchsbauer Hans Lothar Verfahren zum Transglutaminase-katalysierten Koppeln von Protein oder Peptid an einen Träger
DE19814860A1 (de) * 1998-04-02 1999-10-07 Fuchsbauer Hans Lothar Bakterielle Transglutaminasen
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US6093424A (en) * 1999-04-27 2000-07-25 Kraft Foods, Inc. Process for making cheese using transglutaminase and a non-rennet protease
US6251445B1 (en) 1999-05-19 2001-06-26 Kraft Foods, Inc. Method for producing enzyme-modified cheese flavorings
US6224914B1 (en) 1999-06-03 2001-05-01 Kraft Foods, Inc. Process for incorporating whey proteins into cheese using transglutaminase
US6270814B1 (en) 1999-06-03 2001-08-07 Kraft Foods, Inc. Incorporation of whey into process cheese
AU776775B2 (en) * 1999-09-17 2004-09-23 Ajinomoto Co., Inc. Salting agent for food processing
KR20010078440A (ko) * 2001-01-11 2001-08-21 김형순,성문희 고분자량의 폴리-감마-글루탐산을 생산하는 내염성 균주바실러스 서브틸리스 청국장
US6416797B1 (en) 2001-02-14 2002-07-09 Kraft Foods Holdings, Inc. Process for making a wheyless cream cheese using transglutaminase
US6572901B2 (en) 2001-05-02 2003-06-03 Kraft Foods Holdings, Inc. Process for making a cheese product using transglutaminase
ES2223227B1 (es) * 2002-05-31 2006-04-16 Consejo Sup. Investig. Cientificas Secuencia de nucleotidos de maiz codificante de una proteina con actividad transglutaminasa, y su uso.
KR100399091B1 (en) * 2002-07-10 2003-09-22 Bioleaders Corp Macromolecular weight poly(gamma-glutamic acid) and its use
US7069233B2 (en) * 2002-12-31 2006-06-27 Bracken Foster & Associates, Llc System and method for identification and notification of elevated over-the-counter medication sales with response coordination
US6908634B2 (en) * 2003-03-20 2005-06-21 Solae, Llc Transglutaminase soy fish and meat products and analogs thereof
ES2642214T3 (es) 2004-01-21 2017-11-15 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
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MX2009006369A (es) 2006-12-15 2010-02-24 Lifebond Ltd Apositos y selladores hemostaticos de gelatina-transglutaminasa.
EA019932B1 (ru) 2007-09-20 2014-07-30 Басф Се Составы, содержащие фунгицидный штамм и активное соединение
CN104031393B (zh) 2008-06-18 2017-08-01 生命连结有限公司 改进的交联组合物
EP2303344A2 (de) * 2008-06-18 2011-04-06 Lifebond Ltd Verfahren und vorrichtungen zur verwendung mit dichtungsmitteln
WO2009153751A2 (en) * 2008-06-18 2009-12-23 Lifebond Ltd A method for enzymatic cross-linking of a protein
AU2009279090A1 (en) * 2008-08-06 2010-02-11 Novo Nordisk Health Care Ag Conjugated proteins with prolonged in vivo efficacy
CA2747825A1 (en) 2009-01-22 2010-07-29 Novo Nordisk Health Care Ag Stable growth hormone compounds
JP2012518029A (ja) 2009-02-19 2012-08-09 ノヴォ・ノルディスク・アー／エス 第ｖｉｉｉ因子の修飾
GB0907323D0 (en) * 2009-04-29 2009-06-10 Dynea Oy Composite material comprising crosslinkable resin of proteinous material
US20100316764A1 (en) * 2009-06-10 2010-12-16 Engrain, LLC Flour supplement compositions and methods for preparing wheat flour
EP2461831B1 (de) 2009-08-06 2018-11-21 Novo Nordisk Health Care AG Wachstumshormone mit verlängerter in-vivo-wirksamkeit
JP5796860B2 (ja) 2009-12-22 2015-10-21 ライフボンド リミテッドＬｉｆｅｂｏｎｄ Ｌｔｄ 架橋マトリックスの特性を調節するための酵素的架橋剤の改変
RU2012134974A (ru) 2010-01-22 2014-02-27 Ново Нордиск Хелс Кеа Аг Стабилизированное соединение гормона роста
RU2605627C2 (ru) 2010-01-22 2016-12-27 Ново Нордиск Хелс Кеа Аг Гормоны роста с пролонгированной эффективностью in vivo
ITPD20100155A1 (it) 2010-05-19 2011-11-20 Univ Padova Metodo per la preparazione di coniugati mediante transglutaminasi
EP2600910B1 (de) 2010-08-05 2016-01-20 Lifebond Ltd Wundverbände mit einer trockenzusammung und haftstoffe
CN101984052B (zh) * 2010-12-09 2012-09-26 江南大学 一种谷氨酰胺转胺酶的分离纯化方法
CN102146361B (zh) * 2011-02-01 2013-06-19 泰兴市一鸣生物制品有限公司 一种分离纯化谷氨酰胺转胺酶的方法
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WO2014009426A2 (en) 2012-07-13 2014-01-16 Innate Pharma Screening of conjugated antibodies
EP2916872B1 (de) 2012-11-09 2019-02-27 Innate Pharma Kennungen für tgase-vermittelte konjugation
WO2014140300A1 (en) 2013-03-15 2014-09-18 Innate Pharma Solid phase tgase-mediated conjugation of antibodies
EP2981282B1 (de) 2013-04-05 2020-11-04 Novo Nordisk Health Care AG Wachstumshormonverbindungsformulierung
WO2014202773A1 (en) 2013-06-20 2014-12-24 Innate Pharma Enzymatic conjugation of polypeptides
JP6744212B2 (ja) 2013-06-21 2020-08-19 イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． ポリペプチドの酵素的結合
BR112016000585A2 (pt) 2013-07-11 2018-03-20 Novartis Ag modificações quimioenzimáticas sítio-específicas de proteína
RU2728235C2 (ru) 2014-06-12 2020-07-28 СиЭсПиСи ДОФЕН КОРПОРЕЙШН Конъюгат антитела и лекарственного средства, композиции на его основе и способы их получения
CN105754892B (zh) * 2016-02-01 2019-09-06 华东师范大学 一种微生物谷氨酰胺转氨酶的分离纯化方法
US11786603B2 (en) 2016-02-26 2023-10-17 Regeneron Pharmaceuticals, Inc. Optimized transglutaminase site-specific antibody conjugation
RS61928B1 (sr) 2016-05-13 2021-06-30 Rockwool Int Proizvodi od mineralne vune
WO2019092148A1 (en) 2017-11-10 2019-05-16 Innate Pharma Antibodies with functionalized glutamine residues
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CN111349594A (zh) * 2018-12-21 2020-06-30 南京百斯杰生物工程有限公司 一株能够生产谷氨酰胺转氨酶的菌株
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CN117063780B (zh) * 2023-10-17 2023-12-26 四川朕源生物科技有限公司 一种冬虫夏草子囊孢子采收培养基及其采收方法
EP4541376A1 (de) 2023-10-17 2025-04-23 ADC Therapeutics SA Antikörper-wirkstoff-konjugate
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Family Cites Families (4)

* Cited by examiner, † Cited by third party
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JPH0665280B2 (ja) * 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
EP0481504B1 (de) * 1990-10-19 1996-01-17 Amano Pharmaceutical Co., Ltd. Rekombinante Transglutaminase
EP0693556B1 (de) * 1994-01-28 2004-10-06 Ajinomoto Co., Inc. Transglutominase aus japanischer auster
DE69535037T2 (de) * 1994-08-26 2006-12-07 Novozymes A/S Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung

Also Published As

Publication number Publication date
EP0726317A2 (de) 1996-08-14
TW403785B (en) 2000-09-01
KR100358824B1 (ko) 2003-01-24
CA2169249A1 (en) 1996-08-10
JPH09131180A (ja) 1997-05-20
AU691714B2 (en) 1998-05-21
US5731183A (en) 1998-03-24
EP0726317B1 (de) 2007-05-02
DE69637054D1 (de) 2007-06-14
AU4337196A (en) 1996-08-15
JP3669390B2 (ja) 2005-07-06
EP0726317A3 (de) 1999-06-09
KR960031608A (ko) 1996-09-17
DE69637054T2 (de) 2007-12-27
US5948662A (en) 1999-09-07

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