ATE361366T1 - Aus bacillus stammende transglutaminase - Google Patents

Aus bacillus stammende transglutaminase

Info

Publication number
ATE361366T1
ATE361366T1 AT96101905T AT96101905T ATE361366T1 AT E361366 T1 ATE361366 T1 AT E361366T1 AT 96101905 T AT96101905 T AT 96101905T AT 96101905 T AT96101905 T AT 96101905T AT E361366 T1 ATE361366 T1 AT E361366T1
Authority
AT
Austria
Prior art keywords
transglutaminase
bacillus
transglutaminase derived
relates
bacilli
Prior art date
Application number
AT96101905T
Other languages
English (en)
Inventor
Katsunori Kobayashi
Shigeru Yamanaka
Kiyoshi Miwa
Shunichi Suzuki
Yuzuru Eto
Yuko Tanita
Kenzo Yokozeki
Kenichi Hashiguchi
Ajinomoto Ken
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE361366T1 publication Critical patent/ATE361366T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96101905T 1995-02-09 1996-02-09 Aus bacillus stammende transglutaminase ATE361366T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2196395 1995-02-09
JP22631695 1995-09-04
JP01307296A JP3669390B2 (ja) 1995-02-09 1996-01-29 バチルス属細菌由来のトランスグルタミナーゼ

Publications (1)

Publication Number Publication Date
ATE361366T1 true ATE361366T1 (de) 2007-05-15

Family

ID=27280100

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96101905T ATE361366T1 (de) 1995-02-09 1996-02-09 Aus bacillus stammende transglutaminase

Country Status (9)

Country Link
US (2) US5731183A (de)
EP (1) EP0726317B1 (de)
JP (1) JP3669390B2 (de)
KR (1) KR100358824B1 (de)
AT (1) ATE361366T1 (de)
AU (1) AU691714B2 (de)
CA (1) CA2169249A1 (de)
DE (1) DE69637054T2 (de)
TW (1) TW403785B (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
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EP0851029A4 (de) 1995-06-08 2001-05-23 Ajinomoto Kk Mikrobieller przess zur produktion von transglutaminase
JP3635801B2 (ja) * 1996-08-01 2005-04-06 味の素株式会社 乳ホエイ蛋白含有粉末及びこれを使用した加工食品
US6821763B2 (en) * 1997-07-04 2004-11-23 Ajinomoto Co., Inc. Process for producing microbial transglutaminase
DE69822251T2 (de) * 1997-07-04 2005-01-27 Ajinomoto Co., Inc. Verfahren zur Herstellung von mikrobieller Transglutaminase
DE19732917C1 (de) * 1997-07-30 1998-10-15 Fuchsbauer Hans Lothar Verfahren zum Transglutaminase-katalysierten Koppeln von Protein oder Peptid an einen Träger
DE19814860A1 (de) * 1998-04-02 1999-10-07 Fuchsbauer Hans Lothar Bakterielle Transglutaminasen
ES2420905T3 (es) * 1999-03-31 2013-08-27 U-Nica Technology Ag Acoplamiento covalente, sin enlazadores, de bacteriorrodopsina en forma de membrana púrpura
US6093424A (en) * 1999-04-27 2000-07-25 Kraft Foods, Inc. Process for making cheese using transglutaminase and a non-rennet protease
US6251445B1 (en) 1999-05-19 2001-06-26 Kraft Foods, Inc. Method for producing enzyme-modified cheese flavorings
US6270814B1 (en) 1999-06-03 2001-08-07 Kraft Foods, Inc. Incorporation of whey into process cheese
US6224914B1 (en) 1999-06-03 2001-05-01 Kraft Foods, Inc. Process for incorporating whey proteins into cheese using transglutaminase
AU776775B2 (en) 1999-09-17 2004-09-23 Ajinomoto Co., Inc. Salting agent for food processing
KR20010078440A (ko) * 2001-01-11 2001-08-21 김형순,성문희 고분자량의 폴리-감마-글루탐산을 생산하는 내염성 균주바실러스 서브틸리스 청국장
US6416797B1 (en) 2001-02-14 2002-07-09 Kraft Foods Holdings, Inc. Process for making a wheyless cream cheese using transglutaminase
US6572901B2 (en) 2001-05-02 2003-06-03 Kraft Foods Holdings, Inc. Process for making a cheese product using transglutaminase
ES2223227B1 (es) 2002-05-31 2006-04-16 Consejo Sup. Investig. Cientificas Secuencia de nucleotidos de maiz codificante de una proteina con actividad transglutaminasa, y su uso.
KR100399091B1 (en) * 2002-07-10 2003-09-22 Bioleaders Corp Macromolecular weight poly(gamma-glutamic acid) and its use
US7069233B2 (en) * 2002-12-31 2006-06-27 Bracken Foster & Associates, Llc System and method for identification and notification of elevated over-the-counter medication sales with response coordination
US6908634B2 (en) * 2003-03-20 2005-06-21 Solae, Llc Transglutaminase soy fish and meat products and analogs thereof
EP2033662B1 (de) 2004-01-21 2012-10-17 Novo Nordisk Health Care AG Transglutaminase vermittelte konjugation von peptiden.
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CN101854960B (zh) 2006-12-15 2014-06-25 生命连结有限公司 明胶-转谷氨酰胺酶止血敷料和密封材料
HUE048086T2 (hu) 2007-09-20 2020-05-28 Bayer Cropscience Lp Fungicid törzset és legalább egy további fungicidet tartalmazó kombinációk
US20110086014A1 (en) * 2008-06-18 2011-04-14 Ishay Attar Method for enzymatic cross-linking of a protein
AU2009261559B2 (en) 2008-06-18 2014-01-16 Lifebond Ltd Improved cross-linked compositions
WO2009153748A2 (en) * 2008-06-18 2009-12-23 Lifebond Ltd Methods and devices for use with sealants
WO2010015668A1 (en) * 2008-08-06 2010-02-11 Novo Nordisk A/S Conjugated proteins with prolonged in vivo efficacy
JP5816097B2 (ja) 2009-01-22 2015-11-18 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 安定な成長ホルモン化合物
US20110306551A1 (en) 2009-02-19 2011-12-15 Novo Nordisk A/S Modification of Factor VIII
GB0907323D0 (en) * 2009-04-29 2009-06-10 Dynea Oy Composite material comprising crosslinkable resin of proteinous material
US20100316764A1 (en) * 2009-06-10 2010-12-16 Engrain, LLC Flour supplement compositions and methods for preparing wheat flour
WO2011015649A1 (en) 2009-08-06 2011-02-10 Novo Nordisk Health Care Ag Growth hormones with prolonged in-vivo efficacy
EP2963111A1 (de) 2009-12-22 2016-01-06 Lifebond Ltd Modifizierung von enzymatischen vernetzern zur steuerung der eigenschaften vernetzter matrizen
PL2525834T3 (pl) 2010-01-22 2020-10-19 Novo Nordisk Health Care Ag Hormony wzrostu o przedłużonej skuteczności in-vivo
RU2012134974A (ru) 2010-01-22 2014-02-27 Ново Нордиск Хелс Кеа Аг Стабилизированное соединение гормона роста
ITPD20100155A1 (it) 2010-05-19 2011-11-20 Univ Padova Metodo per la preparazione di coniugati mediante transglutaminasi
DK2600910T3 (en) 2010-08-05 2016-04-04 Lifebond Ltd Wound dressings and adhesives COMPREHENSIVE DRYING FORMATIONS
CN101984052B (zh) * 2010-12-09 2012-09-26 江南大学 一种谷氨酰胺转胺酶的分离纯化方法
CN102146361B (zh) * 2011-02-01 2013-06-19 泰兴市一鸣生物制品有限公司 一种分离纯化谷氨酰胺转胺酶的方法
FI126431B (fi) * 2011-06-16 2016-11-30 Valio Oy Juusto ja sen valmistus
CA2858806A1 (en) 2011-12-23 2013-06-27 Innate Pharma Enzymatic conjugation of polypeptides
EP2872894B1 (de) 2012-07-13 2019-04-17 Innate Pharma Screening von konjugierten antikörpern
EP2916872B1 (de) 2012-11-09 2019-02-27 Innate Pharma Kennungen für tgase-vermittelte konjugation
US10611824B2 (en) 2013-03-15 2020-04-07 Innate Pharma Solid phase TGase-mediated conjugation of antibodies
ES2841123T3 (es) 2013-04-05 2021-07-07 Formulacion Del Compuesto De La Hormona De Crecimiento Formulación del compuesto de la hormona de crecimiento
WO2014202773A1 (en) 2013-06-20 2014-12-24 Innate Pharma Enzymatic conjugation of polypeptides
KR20160042871A (ko) 2013-06-21 2016-04-20 이나뜨 파르마, 에스.아. 폴리펩티드의 효소적 콘쥬게이션
KR20160040556A (ko) 2013-07-11 2016-04-14 노파르티스 아게 미생물 트랜스글루타미나제를 사용한 리신-특이적 화학효소적 단백질 변형
CA2951887A1 (en) 2014-06-12 2015-12-17 Cspc Dophen Corporation Homogenous antibody drug conjugates via enzymatic methods
CN105754892B (zh) * 2016-02-01 2019-09-06 华东师范大学 一种微生物谷氨酰胺转氨酶的分离纯化方法
EP3419670A2 (de) 2016-02-26 2019-01-02 Regeneron Pharmaceuticals, Inc. Optimierte ortsspezifische transglutaminase-antikörperkonjugation
SI3455425T1 (sl) 2016-05-13 2021-11-30 Rockwool International A/S Metoda za zagotavljanje izolacije strukture
WO2019092148A1 (en) 2017-11-10 2019-05-16 Innate Pharma Antibodies with functionalized glutamine residues
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
CN111349594A (zh) * 2018-12-21 2020-06-30 南京百斯杰生物工程有限公司 一株能够生产谷氨酰胺转氨酶的菌株
CN114245802B (zh) 2019-06-20 2024-10-15 石药集团巨石生物制药有限公司 修饰的il-2蛋白、peg偶联物及其用途
US11771105B2 (en) 2021-08-17 2023-10-03 New Culture Inc. Dairy-like compositions and related methods
JP2025505835A (ja) 2022-02-22 2025-02-28 アーデーセー セラピューティクス ソシエテ アノニム トリミングされたｎ－グリカンを含むｆｃ領域でのトランスグルタミナーゼを伴うコンジュゲーション方法
EP4541376A1 (de) 2023-10-17 2025-04-23 ADC Therapeutics SA Antikörper-wirkstoff-konjugate
CN117063780B (zh) * 2023-10-17 2023-12-26 四川朕源生物科技有限公司 一种冬虫夏草子囊孢子采收培养基及其采收方法
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WO2026044143A1 (en) * 2024-08-21 2026-02-26 New Culture Inc. Compositions made from crosslinked single casein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665280B2 (ja) * 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
EP0481504B1 (de) * 1990-10-19 1996-01-17 Amano Pharmaceutical Co., Ltd. Rekombinante Transglutaminase
US5736356A (en) * 1994-01-28 1998-04-07 Ajinomoto Co., Inc. Transglutaminase originating from Crassostrea gigas
EP0777726B1 (de) * 1994-08-26 2006-06-07 Novozymes A/S Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung

Also Published As

Publication number Publication date
US5731183A (en) 1998-03-24
US5948662A (en) 1999-09-07
AU691714B2 (en) 1998-05-21
DE69637054T2 (de) 2007-12-27
EP0726317B1 (de) 2007-05-02
EP0726317A3 (de) 1999-06-09
DE69637054D1 (de) 2007-06-14
TW403785B (en) 2000-09-01
KR100358824B1 (ko) 2003-01-24
CA2169249A1 (en) 1996-08-10
KR960031608A (ko) 1996-09-17
AU4337196A (en) 1996-08-15
EP0726317A2 (de) 1996-08-14
JP3669390B2 (ja) 2005-07-06
JPH09131180A (ja) 1997-05-20

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