ATE361930T1 - Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht - Google Patents

Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht

Info

Publication number
ATE361930T1
ATE361930T1 AT98926586T AT98926586T ATE361930T1 AT E361930 T1 ATE361930 T1 AT E361930T1 AT 98926586 T AT98926586 T AT 98926586T AT 98926586 T AT98926586 T AT 98926586T AT E361930 T1 ATE361930 T1 AT E361930T1
Authority
AT
Austria
Prior art keywords
chromatography
protein purification
subsequent filtration
loaded layer
composition
Prior art date
Application number
AT98926586T
Other languages
English (en)
Inventor
Gregory Blank
Daljit Narindray
Gerardo Zapata
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21968517&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE361930(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE361930T1 publication Critical patent/ATE361930T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98926586T 1997-06-13 1998-06-12 Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht ATE361930T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5095197P 1997-06-13 1997-06-13

Publications (1)

Publication Number Publication Date
ATE361930T1 true ATE361930T1 (de) 2007-06-15

Family

ID=21968517

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98926586T ATE361930T1 (de) 1997-06-13 1998-06-12 Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht

Country Status (12)

Country Link
US (4) US6121428A (de)
EP (1) EP0998486B2 (de)
JP (1) JP2001510483A (de)
AT (1) ATE361930T1 (de)
AU (1) AU735883C (de)
CA (1) CA2289665C (de)
DE (1) DE69837760T3 (de)
DK (1) DK0998486T4 (de)
ES (1) ES2287976T3 (de)
IL (1) IL132838A (de)
PT (1) PT998486E (de)
WO (1) WO1998056808A1 (de)

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US6121428A (en) * 1997-06-13 2000-09-19 Genentech, Inc. Protein recovery
JP4588960B2 (ja) * 2000-02-22 2010-12-01 メルク セローノ ソシエテ アノニム ｈＣＧの精製方法及び本法により精製した組換えｈＣＧ
CA2417432C (en) 2000-09-01 2010-11-02 The Center For Blood Research, Inc. Modified polypeptides stabilized in a desired conformation and methods for producing same
WO2002060377A2 (en) * 2000-12-15 2002-08-08 The Johns Hopkins University The separation, identification and quantitation of protein mixtures
US20040067599A1 (en) * 2001-12-14 2004-04-08 Katz Joseph L. Separation identification and quantitation of protein mixtures
PL374311A1 (en) * 2001-12-21 2005-10-03 Immunex Corporation Methods for purifying protein
US20050271639A1 (en) * 2002-08-22 2005-12-08 Penn Marc S Genetically engineered cells for therapeutic applications
SI1539798T1 (sl) 2002-09-06 2011-03-31 Genentech Inc Postopek za proteinsko ekstrakcijo
AU2004230670B2 (en) * 2003-01-09 2010-11-25 Genentech, Inc. Purification of polypeptides
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
CN100526453C (zh) * 2005-05-20 2009-08-12 麦克奥迪实业集团有限公司 激光显微切割后细胞收集方法
EP1926751A1 (de) * 2005-09-20 2008-06-04 Amgen Inc. Verfahren zur erzeugung von f(ab')2-antikörperfragmenten
WO2007075283A2 (en) * 2005-12-06 2007-07-05 Amgen Inc. Polishing steps used in multi-step protein purification processes
WO2008079280A1 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
ES2520044T3 (es) * 2007-03-30 2014-11-11 The Cleveland Clinic Foundation SDF-1 para su uso en el tratamiento de trastornos vasculares periféricos isquémicos
MX2009012786A (es) 2007-06-01 2009-12-10 Hoffmann La Roche Purificacion de inmunoglobulina.
CA2709398C (en) * 2007-12-14 2017-11-07 The Cleveland Clinic Foundation Use of stromal cell-derived factor 1 for promoting wound healing
US20100190963A1 (en) 2008-12-16 2010-07-29 Millipore Corporation Stirred Tank Reactor And Method
EP2379108B1 (de) 2008-12-22 2014-06-25 F. Hoffmann-La Roche AG Immunoglobulin-reinigung
JP5856059B2 (ja) 2009-08-28 2016-02-09 ザ クリーブランド クリニック ファウンデーション 虚血組織を治療するためのｓｄｆ−１送達
CA2773428A1 (en) * 2009-09-10 2011-03-17 Lonza Biologics Plc Method and system for polypeptide purification
EP2571903B1 (de) 2010-05-17 2019-09-04 EMD Millipore Corporation Stimulusreaktive polymere zur aufreinigung von biomolekülen
MX350957B (es) 2011-11-23 2017-09-27 Medimmune Llc Moleculas de union especificas para her3 y usos de las mismas.
WO2015048008A2 (en) 2013-09-24 2015-04-02 Medimmune, Llc Binding molecules specific for her3 and uses thereof
US10745490B2 (en) 2014-04-11 2020-08-18 Celldex Therapeutics, Inc. Anti-ErbB antibodies and methods of use thereof

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CA1044537A (en) * 1973-05-09 1978-12-19 Amf Incorporated Filter medium and process
FR2413974A1 (fr) * 1978-01-06 1979-08-03 David Bernard Sechoir pour feuilles imprimees par serigraphie
CA1148872A (en) * 1979-04-06 1983-06-28 Eugene A. Ostreicher Filter with inorganic cationic colloidal silica
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
SE451843B (sv) * 1983-05-09 1987-11-02 Gambro Lundia Ab Forfarande for utvinning av en forening
US4604208A (en) * 1983-12-29 1986-08-05 Chaokang Chu Liquid filtration using an anionic microporous membrane
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GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
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WO1993008829A1 (en) * 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
DE69233528T2 (de) * 1991-11-25 2006-03-16 Enzon, Inc. Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
US5932448A (en) * 1991-11-29 1999-08-03 Protein Design Labs., Inc. Bispecific antibody heterodimers
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JP3505283B2 (ja) 1995-08-01 2004-03-08 日本ファイリング株式会社 電動台車の荷位置制御装置
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Also Published As

Publication number Publication date
IL132838A (en) 2004-08-31
EP0998486A1 (de) 2000-05-10
US20040138426A1 (en) 2004-07-15
US6121428A (en) 2000-09-19
IL132838A0 (en) 2001-03-19
US6716598B2 (en) 2004-04-06
US6322997B1 (en) 2001-11-27
PT998486E (pt) 2007-08-21
EP0998486B2 (de) 2012-02-01
US20020058324A1 (en) 2002-05-16
DK0998486T3 (da) 2007-09-10
DK0998486T4 (da) 2012-05-14
AU7838898A (en) 1998-12-30
CA2289665A1 (en) 1998-12-17
CA2289665C (en) 2005-08-09
DE69837760D1 (de) 2007-06-21
AU735883B2 (en) 2001-07-19
AU735883C (en) 2002-02-07
DE69837760T3 (de) 2012-06-21
DE69837760T2 (de) 2008-02-28
WO1998056808A1 (en) 1998-12-17
JP2001510483A (ja) 2001-07-31
ES2287976T3 (es) 2007-12-16
EP0998486B1 (de) 2007-05-09

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