DK0998486T3 - Proteinudvinding ved kromatografi efterfulgt af filtrering på en ladet fase - Google Patents

Proteinudvinding ved kromatografi efterfulgt af filtrering på en ladet fase

Info

Publication number
DK0998486T3
DK0998486T3 DK98926586T DK98926586T DK0998486T3 DK 0998486 T3 DK0998486 T3 DK 0998486T3 DK 98926586 T DK98926586 T DK 98926586T DK 98926586 T DK98926586 T DK 98926586T DK 0998486 T3 DK0998486 T3 DK 0998486T3
Authority
DK
Denmark
Prior art keywords
filtration
protein recovery
chromatography followed
composition
reagent
Prior art date
Application number
DK98926586T
Other languages
English (en)
Other versions
DK0998486T4 (da
Inventor
Gerardo A Zapata
Gregory S Blank
Daljit S Narindray
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21968517&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0998486(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DK0998486T3 publication Critical patent/DK0998486T3/da
Application granted granted Critical
Publication of DK0998486T4 publication Critical patent/DK0998486T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK98926586.3T 1997-06-13 1998-06-12 Proteinoprensning ved kromatografi efterfulgt af filtrering på en ladet fase DK0998486T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5095197P 1997-06-13 1997-06-13
PCT/US1998/012334 WO1998056808A1 (en) 1997-06-13 1998-06-12 Protein recovery by chromatography followed by filtration upon a charged layer

Publications (2)

Publication Number Publication Date
DK0998486T3 true DK0998486T3 (da) 2007-09-10
DK0998486T4 DK0998486T4 (da) 2012-05-14

Family

ID=21968517

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98926586.3T DK0998486T4 (da) 1997-06-13 1998-06-12 Proteinoprensning ved kromatografi efterfulgt af filtrering på en ladet fase

Country Status (12)

Country Link
US (4) US6121428A (da)
EP (1) EP0998486B2 (da)
JP (1) JP2001510483A (da)
AT (1) ATE361930T1 (da)
AU (1) AU735883C (da)
CA (1) CA2289665C (da)
DE (1) DE69837760T3 (da)
DK (1) DK0998486T4 (da)
ES (1) ES2287976T3 (da)
IL (1) IL132838A (da)
PT (1) PT998486E (da)
WO (1) WO1998056808A1 (da)

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CA2289665C (en) * 1997-06-13 2005-08-09 Genentech, Inc. Protein recovery by chromatography followed by filtration upon a charged layer
IL151308A0 (en) * 2000-02-22 2003-04-10 Applied Research Systems PURIFICATION OF hCG AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
AU2001287000A1 (en) * 2000-09-01 2002-03-13 The Center For Blood Research, Inc. Modified polypeptides stabilized in a desired conformation and methods for producing same
AU2002246621A1 (en) * 2000-12-15 2002-08-12 The Johns Hopkins University The separation, identification and quantitation of protein mixtures
US20040067599A1 (en) * 2001-12-14 2004-04-08 Katz Joseph L. Separation identification and quantitation of protein mixtures
WO2003059935A2 (en) * 2001-12-21 2003-07-24 Immunex Corporation Methods for purifying protein
US20050271639A1 (en) * 2002-08-22 2005-12-08 Penn Marc S Genetically engineered cells for therapeutic applications
US6967241B2 (en) * 2002-09-06 2005-11-22 Genentech, Inc. Process for protein extraction
JP2006517415A (ja) 2003-01-09 2006-07-27 ジェネンテック・インコーポレーテッド ポリペプチドの精製
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
CN100526453C (zh) * 2005-05-20 2009-08-12 麦克奥迪实业集团有限公司 激光显微切割后细胞收集方法
EP1926751A1 (en) * 2005-09-20 2008-06-04 Amgen Inc. Method for generating f(ab')2 antibody fragments
WO2007075283A2 (en) * 2005-12-06 2007-07-05 Amgen Inc. Polishing steps used in multi-step protein purification processes
WO2008079280A1 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
JP2010523496A (ja) 2007-03-30 2010-07-15 ザ クリーブランド クリニック ファウンデーション 虚血障害の治療方法
BRPI0812288A2 (pt) 2007-06-01 2014-11-25 Hoffmann La Roche Purificação de imunoglobulina.
WO2009079451A2 (en) 2007-12-14 2009-06-25 The Cleveland Clinic Foundation Compositions and methods of promoting wound healing
CN102257122B (zh) 2008-12-16 2015-07-29 Emd密理博公司 搅拌槽反应器及方法
ES2488542T3 (es) 2008-12-22 2014-08-27 F. Hoffmann-La Roche Ag Purificación de inmunoglobulinas
CA2772610C (en) 2009-08-28 2018-01-23 The Cleveland Clinic Foundation Sdf-1 delivery for treating ischemic tissue
EP2475678B1 (en) * 2009-09-10 2014-10-08 Lonza Biologics Plc. Method and system for polypeptide purification
CN107312062B (zh) 2010-05-17 2021-03-16 Emd密理博公司 用于纯化生物分子的刺激响应性聚合物
JP6180425B2 (ja) 2011-11-23 2017-08-23 メディミューン，エルエルシー Ｈｅｒ３に特異的な結合分子及びそれらの使用
US11305012B2 (en) 2013-09-24 2022-04-19 Medimmune, Llc Binding molecules specific for HER3 and uses thereof
US10745490B2 (en) 2014-04-11 2020-08-18 Celldex Therapeutics, Inc. Anti-ErbB antibodies and methods of use thereof

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CA1044537A (en) * 1973-05-09 1978-12-19 Amf Incorporated Filter medium and process
FR2413974A1 (fr) * 1978-01-06 1979-08-03 David Bernard Sechoir pour feuilles imprimees par serigraphie
CA1148872A (en) * 1979-04-06 1983-06-28 Eugene A. Ostreicher Filter with inorganic cationic colloidal silica
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
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US4604208A (en) * 1983-12-29 1986-08-05 Chaokang Chu Liquid filtration using an anionic microporous membrane
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US4983722A (en) † 1988-06-08 1991-01-08 Miles Inc. Removal of protein A from antibody preparations
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US4981591A (en) * 1989-04-07 1991-01-01 Cuno, Incorporated Cationic charge modified filter media
DE3920358A1 (de) * 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
ES2096590T3 (es) * 1989-06-29 1997-03-16 Medarex Inc Reactivos biespecificos para la terapia del sida.
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CA2289665C (en) * 1997-06-13 2005-08-09 Genentech, Inc. Protein recovery by chromatography followed by filtration upon a charged layer

Also Published As

Publication number Publication date
DE69837760D1 (de) 2007-06-21
DE69837760T2 (de) 2008-02-28
IL132838A (en) 2004-08-31
AU7838898A (en) 1998-12-30
DE69837760T3 (de) 2012-06-21
JP2001510483A (ja) 2001-07-31
CA2289665A1 (en) 1998-12-17
AU735883B2 (en) 2001-07-19
EP0998486B2 (en) 2012-02-01
DK0998486T4 (da) 2012-05-14
US6716598B2 (en) 2004-04-06
AU735883C (en) 2002-02-07
US20040138426A1 (en) 2004-07-15
WO1998056808A1 (en) 1998-12-17
IL132838A0 (en) 2001-03-19
ATE361930T1 (de) 2007-06-15
US6121428A (en) 2000-09-19
US20020058324A1 (en) 2002-05-16
CA2289665C (en) 2005-08-09
US6322997B1 (en) 2001-11-27
ES2287976T3 (es) 2007-12-16
EP0998486A1 (en) 2000-05-10
EP0998486B1 (en) 2007-05-09
PT998486E (pt) 2007-08-21

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